메뉴 건너뛰기




Volumn 22, Issue 5, 2003, Pages 1147-1157

FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts

Author keywords

Akt; Fusion; Myoblast; Rhabdomyosarcoma

Indexed keywords

HYBRID PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

EID: 0037416153     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg116     Document Type: Article
Times cited : (147)

References (38)
  • 1
    • 0035909313 scopus 로고    scopus 로고
    • Forkhead transcription factors contribute to execution of the mitotic programme in mammals
    • Alvarez, B., Martinez, A.C., Burgering, B.M. and Carrera, A.C. (2001) Forkhead transcription factors contribute to execution of the mitotic programme in mammals. Nature, 413, 744-747.
    • (2001) Nature , vol.413 , pp. 744-747
    • Alvarez, B.1    Martinez, A.C.2    Burgering, B.M.3    Carrera, A.C.4
  • 2
    • 0032191350 scopus 로고    scopus 로고
    • Muscle differentiation: More complexity to the network of myogenic regulators
    • Arnold, H.H. and Winter, B. (1998) Muscle differentiation: more complexity to the network of myogenic regulators. Curr. Opin. Genet. Dev., 8, 539-544.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 539-544
    • Arnold, H.H.1    Winter, B.2
  • 4
    • 0035839886 scopus 로고    scopus 로고
    • Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
    • Barr, F.G. (2001) Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene, 20, 5736-5746.
    • (2001) Oncogene , vol.20 , pp. 5736-5746
    • Barr, F.G.1
  • 6
    • 0023932371 scopus 로고
    • Secreted placenta1 alkaline phosphatase: A powerful new quantitative indicator of gene expression in eukaryotic cells
    • Berger, J., Hauber, J., Hauber, R., Geiger, R. and Cullen, B.R. (1988) Secreted placenta1 alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells. Gene, 66, 1-10.
    • (1988) Gene , vol.66 , pp. 1-10
    • Berger, J.1    Hauber, J.2    Hauber, R.3    Geiger, R.4    Cullen, B.R.5
  • 7
    • 0033595011 scopus 로고    scopus 로고
    • Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
    • Biggs, W.H., 3rd, Meisenhelder, J., Hunter, T., Cavenee, W.K. and Arden, K.C. (1999) Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl Acad. Sci. USA, 96, 7421-7426.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7421-7426
    • Biggs W.H. III1    Meisenhelder, J.2    Hunter, T.3    Cavenee, W.K.4    Arden, K.C.5
  • 8
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen, P. and Hunter, T. (2001) Oncogenic kinase signalling. Nature, 411, 355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 9
    • 0035034038 scopus 로고    scopus 로고
    • Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX
    • Brownawell, A.M., Kops, G.J., Macara, I.G. and Burgering, B.M. (2001) Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Mol. Cell. Biol., 21, 3534-3546.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3534-3546
    • Brownawell, A.M.1    Kops, G.J.2    Macara, I.G.3    Burgering, B.M.4
  • 10
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet, A. et al. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell, 96, 857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1
  • 11
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • Brunet, A., Park, J., Tran, H., Hu, L.S., Hemmings, B.A. and Greenberg, M.E. (2001) Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol. Cell. Biol., 21, 952-965.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5    Greenberg, M.E.6
  • 12
    • 0034698170 scopus 로고    scopus 로고
    • Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1
    • Collado, M. et al. (2000) Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1. J. Biol. Chem., 275, 21960-21968.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21960-21968
    • Collado, M.1
  • 13
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross, D.A., Alessi, D.R., Cohen, P., Andjelkovich, M. and Hemmings, B.A. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature, 378, 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 14
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
    • Davis, R.J., D'Cruz, C.M., Lovell, M.A., Biegel, J.A. and Barr, F.G. (1994) Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res., 54, 2869-2872.
    • (1994) Cancer Res. , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lovell, M.A.3    Biegel, J.A.4    Barr, F.G.5
  • 15
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers, P.F., Medema, R.H., Lammers, J.W., Koenderman, L. and Coffer, P.J. (2000a) Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr. Biol., 10, 1201-1204.
    • (2000) Curr. Biol. , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 16
    • 0034459180 scopus 로고    scopus 로고
    • Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1)
    • Dijkers, P.F. et al. (2000b) Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). Mol. Cell. Biol., 20, 9138-9148.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 9138-9148
    • Dijkers, P.F.1
  • 18
    • 0034661826 scopus 로고    scopus 로고
    • Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
    • Furuyama, T., Nakazawa, T., Nakano, I. and Mori, N. (2000) Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem. J., 349, 629-634.
    • (2000) Biochem. J. , vol.349 , pp. 629-634
    • Furuyama, T.1    Nakazawa, T.2    Nakano, I.3    Mori, N.4
  • 19
    • 0027521658 scopus 로고
    • Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
    • published erratum appears in Nat. Genet. 1994 Feb;6(2):214
    • Galili, N., Davis, R.J., Fredericks, W.J., Mukhopadhyay, S., Rauscher, F.J.D., Emanuel, B.S., Rovera, G. and Barr, F.G. (1993) Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma [published erratum appears in Nat. Genet. 1994 Feb;6(2):214]. Nat. Genet., 5, 230-235.
    • (1993) Nat. Genet. , vol.5 , pp. 230-235
    • Galili, N.1    Davis, R.J.2    Fredericks, W.J.3    Mukhopadhyay, S.4    Rauscher, F.J.D.5    Emanuel, B.S.6    Rovera, G.7    Barr, F.G.8
  • 20
    • 0033546192 scopus 로고    scopus 로고
    • Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
    • Guo, S., Rena, G., Cichy, S., He, X., Cohen, P. and Unterman, T. (1999) Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J. Biol. Chem., 274, 17184-17192.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17184-17192
    • Guo, S.1    Rena, G.2    Cichy, S.3    He, X.4    Cohen, P.5    Unterman, T.6
  • 21
    • 0033785487 scopus 로고    scopus 로고
    • Role of the forkhead transcription family member, FKHR, in thymocyte differentiation
    • Leenders, H., Whiffield, S., Benoist, C. and Mathis, D. (2000) Role of the forkhead transcription family member, FKHR, in thymocyte differentiation. Eur. J. Immunol., 30, 2980-2990.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2980-2990
    • Leenders, H.1    Whiffield, S.2    Benoist, C.3    Mathis, D.4
  • 22
    • 0034643331 scopus 로고    scopus 로고
    • AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
    • Medema, R.H., Kops, G.J., Bos, J.L. and Burgering, B.M. (2000) AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature, 404, 782-787.
    • (2000) Nature , vol.404 , pp. 782-787
    • Medema, R.H.1    Kops, G.J.2    Bos, J.L.3    Burgering, B.M.4
  • 23
    • 0033522897 scopus 로고    scopus 로고
    • Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a wortmannin-sensitive pathway
    • Nakae, J., Park, B.C. and Accili, D. (1999) Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a wortmannin-sensitive pathway. J. Biol. Chem., 274, 15982-15985.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15982-15985
    • Nakae, J.1    Park, B.C.2    Accili, D.3
  • 24
    • 0034161544 scopus 로고    scopus 로고
    • Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
    • Nakae, J., Barr, V., and Accili, D. (2000) Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR. EMBO J., 19, 989-996.
    • (2000) EMBO J. , vol.19 , pp. 989-996
    • Nakae, J.1    Barr, V.2    Accili, D.3
  • 25
    • 0035797921 scopus 로고    scopus 로고
    • Insulin regulation of gene expression through the forkhead transcription factor Foxol (Fkhr) requires kinases distinct from Akt
    • Nakae, J., Kitamura, T., Ogawa, W., Kasuga, M. and Accili, D. (2001) Insulin regulation of gene expression through the forkhead transcription factor Foxol (Fkhr) requires kinases distinct from Akt. Biochemistry, 40, 11768-11776.
    • (2001) Biochemistry , vol.40 , pp. 11768-11776
    • Nakae, J.1    Kitamura, T.2    Ogawa, W.3    Kasuga, M.4    Accili, D.5
  • 26
    • 0034462121 scopus 로고    scopus 로고
    • Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN
    • Nakamura, N., Ramaswamy, S., Vazquez, F., Signoretti, S., Loda, M. and Sellers, W.R. (2000) Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. Mol. Cell. Biol., 20, 8969-8982.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8969-8982
    • Nakamura, N.1    Ramaswamy, S.2    Vazquez, F.3    Signoretti, S.4    Loda, M.5    Sellers, W.R.6
  • 27
    • 0030748907 scopus 로고    scopus 로고
    • Evidence for a role of CRM1 in signal-mediated nuclear protein export
    • Ossareh-Nazari, B., Bachelerie, F. and Dargemont, C. (1997) Evidence for a role of CRM1 in signal-mediated nuclear protein export. Science, 278, 141-144.
    • (1997) Science , vol.278 , pp. 141-144
    • Ossareh-Nazari, B.1    Bachelerie, F.2    Dargemont, C.3
  • 28
    • 0028264320 scopus 로고
    • Primary mouse myoblast purification, characterization and transplantation for cell-mediated gene therapy
    • Rando, T.A. and Blau, H.M. (1994) Primary mouse myoblast purification, characterization and transplantation for cell-mediated gene therapy. J. Cell Biol., 125, 1275-1287.
    • (1994) J. Cell Biol. , vol.125 , pp. 1275-1287
    • Rando, T.A.1    Blau, H.M.2
  • 29
    • 0033546439 scopus 로고    scopus 로고
    • Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
    • Rena, G., Guo, S., Cichy, S.C., Unterman, T.G. and Cohen, P. (1999) Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J. Biol. Chem., 274, 17179-17183.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17179-17183
    • Rena, G.1    Guo, S.2    Cichy, S.C.3    Unterman, T.G.4    Cohen, P.5
  • 30
    • 0035000532 scopus 로고    scopus 로고
    • Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury
    • Rende, M. et al. (2001) Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury. Muscle Nerve, 24, 799-808.
    • (2001) Muscle Nerve , vol.24 , pp. 799-808
    • Rende, M.1
  • 31
    • 0036134975 scopus 로고    scopus 로고
    • Suppression of Akt signaling induces Fas ligand expression: Involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation
    • Suhara, T., Kim, H.S., Kirshenbaum, L.A. and Walsh, K. (2002) Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation. Mol. Cell. Biol., 22, 680-691.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 680-691
    • Suhara, T.1    Kim, H.S.2    Kirshenbaum, L.A.3    Walsh, K.4
  • 32
    • 45149083131 scopus 로고    scopus 로고
    • Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems
    • Coligan, J.E., Kruisbeek, A.M., Margulies, D.H., Shevach, E.M. and Strober, W. (eds). John Wiley and Sons, Harvard
    • Swift, S., Lorens, J., Achacoso, P. and Nolan, G.P. (1999) Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems. In Coligan, J.E., Kruisbeek, A.M., Margulies, D.H., Shevach, E.M. and Strober, W. (eds), Current Protocols in Immunology. John Wiley and Sons, Harvard, Vol. 2, p. 10.28.
    • (1999) Current Protocols in Immunology , vol.2 , pp. 1028
    • Swift, S.1    Lorens, J.2    Achacoso, P.3    Nolan, G.P.4
  • 33
    • 0039425278 scopus 로고    scopus 로고
    • Negative regulation of the forkhead transcription factor FKHR by Akt
    • Tang, E.D., Nunez, G., Barr, F.G. and Guan, K.L. (1999) Negative regulation of the forkhead transcription factor FKHR by Akt. J. Biol. Chem., 274, 16741-16746.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16741-16746
    • Tang, E.D.1    Nunez, G.2    Barr, F.G.3    Guan, K.L.4
  • 34
    • 0034629298 scopus 로고    scopus 로고
    • Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription
    • Tomizawa, M., Kumar, A., Perrot, V., Nakae, J., Accili, D., Rechler, M.M. and Kumaro, A. (2000) Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription. J. Biol. Chem., 275, 7289-7295.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7289-7295
    • Tomizawa, M.1    Kumar, A.2    Perrot, V.3    Nakae, J.4    Accili, D.5    Rechler, M.M.6    Kumaro, A.7
  • 35
    • 0034426034 scopus 로고    scopus 로고
    • Hot-stop PCR: A simple and general assay for linear quantitation of allele ratios
    • Uejima, H., Lee, M.P., Cui, H. and Feinberg, A.P. (2000) Hot-stop PCR: a simple and general assay for linear quantitation of allele ratios. Nat. Genet., 25, 375-376.
    • (2000) Nat. Genet. , vol.25 , pp. 375-376
    • Uejima, H.1    Lee, M.P.2    Cui, H.3    Feinberg, A.P.4
  • 36
    • 0029884657 scopus 로고    scopus 로고
    • Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain
    • Virbasius, J.V., Guilherme, A. and Czech, M.P. (1996) Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain. J. Biol. Chem., 271, 13304-13307.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13304-13307
    • Virbasius, J.V.1    Guilherme, A.2    Czech, M.P.3
  • 37
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos, C.J., Matter, W.F., Hui, K.Y. and Brown, R.F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem., 269, 5241-5248.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 38
    • 0035399638 scopus 로고    scopus 로고
    • Progressive cerebellar, auditory and esophageal dysfunction caused by targeted disruption of the frizzled-4 gene
    • Wang, Y., Huso, D., Cahill, H., Ryugo, D. and Nathans, J. (2001) Progressive cerebellar, auditory and esophageal dysfunction caused by targeted disruption of the frizzled-4 gene. J Neurosci., 21, 4761-4771.
    • (2001) J Neurosci. , vol.21 , pp. 4761-4771
    • Wang, Y.1    Huso, D.2    Cahill, H.3    Ryugo, D.4    Nathans, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.