-
1
-
-
0036366824
-
Classifying the medulloblastoma: Insights from morphology and molecular genetics
-
Ellison D. 2002. Classifying the medulloblastoma: insights from morphology and molecular genetics. Neuropathol. Appl. Neurobiol. 28:257-82
-
(2002)
Neuropathol. Appl. Neurobiol
, vol.28
, pp. 257-282
-
-
Ellison, D.1
-
2
-
-
1842614251
-
Clinical, histopathologic, and molecular markers of prognosis: Toward a new disease risk stratification system for medulloblastoma
-
Gajjar A, Hernan R, Kocak M, Fuller C, Lee Y, et al. 2004. Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma. J. Clin. Oncol. 22:984-93
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 984-993
-
-
Gajjar, A.1
Hernan, R.2
Kocak, M.3
Fuller, C.4
Lee, Y.5
-
6
-
-
0015812215
-
Primitive neuroectodermal tumors of the brain in children
-
Hart MN, Earle KM. 1973. Primitive neuroectodermal tumors of the brain in children. Cancer 32:890-7
-
(1973)
Cancer
, vol.32
, pp. 890-897
-
-
Hart, M.N.1
Earle, K.M.2
-
7
-
-
84938457755
-
The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors
-
Rorke LB. 1983. The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors. J. Neuropathol. Exp. Neurol. 42:1-15
-
(1983)
J. Neuropathol. Exp. Neurol
, vol.42
, pp. 1-15
-
-
Rorke, L.B.1
-
8
-
-
33947521508
-
Nodule formation and desmoplasia in medulloblastomas: Defining the nodular/desmoplastic variant and its biological behaviour
-
McManamy CS, Pears J, Weston CL, Hanzely Z, Ironside JW, et al. 2007. Nodule formation and desmoplasia in medulloblastomas: defining the nodular/desmoplastic variant and its biological behaviour. Brain Pathol. 17:151-64
-
(2007)
Brain Pathol
, vol.17
, pp. 151-164
-
-
McManamy, C.S.1
Pears, J.2
Weston, C.L.3
Hanzely, Z.4
Ironside, J.W.5
-
9
-
-
0021854696
-
Embryonal central neuroepithelial tumors and their differentiating potential. A cytogenetic view of a complex neuro-oncological problem
-
Rubinstein LJ. 1985. Embryonal central neuroepithelial tumors and their differentiating potential. A cytogenetic view of a complex neuro-oncological problem. J. Neurosurg. 62:795-805
-
(1985)
J. Neurosurg
, vol.62
, pp. 795-805
-
-
Rubinstein, L.J.1
-
12
-
-
0026043909
-
The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma
-
Evans DG, Farndon PA, Burnell LD, Gattamaneni HR, Birch JM. 1991. The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br. J. Cancer 64:959-61
-
(1991)
Br. J. Cancer
, vol.64
, pp. 959-961
-
-
Evans, D.G.1
Farndon, P.A.2
Burnell, L.D.3
Gattamaneni, H.R.4
Birch, J.M.5
-
13
-
-
0030798827
-
Brain tumor-polyposis syndrome: Two genetic diseases?
-
Paraf F, Jothy S, Van Meir EG. 1997. Brain tumor-polyposis syndrome: two genetic diseases? J. Clin. Oncol. 15:2744-58
-
(1997)
J. Clin. Oncol
, vol.15
, pp. 2744-2758
-
-
Paraf, F.1
Jothy, S.2
Van Meir, E.G.3
-
14
-
-
0031672984
-
Pineoblastoma presenting in familial adenomatous polyposis (FAP): Random association, FAP variant or Turcot syndrome?
-
Ikeda J, Sawamura Y, van Meir EG. 1998. Pineoblastoma presenting in familial adenomatous polyposis (FAP): random association, FAP variant or Turcot syndrome? Br. J. Neurosurg. 12:576-78
-
(1998)
Br. J. Neurosurg
, vol.12
, pp. 576-578
-
-
Ikeda, J.1
Sawamura, Y.2
van Meir, E.G.3
-
15
-
-
0033565715
-
Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors
-
Russo C, Pellarin M, Tingby O, Bollen AW, Lamborn KR, et al. 1999. Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors. Cancer 86:331-39
-
(1999)
Cancer
, vol.86
, pp. 331-339
-
-
Russo, C.1
Pellarin, M.2
Tingby, O.3
Bollen, A.W.4
Lamborn, K.R.5
-
16
-
-
0026663357
-
Large-cell medulloblastomas. A distinct variant with highly aggressive behavior
-
Giangaspero F, Rigobello L, Badiali M, Loda M, Andreini L, et al. 1992. Large-cell medulloblastomas. A distinct variant with highly aggressive behavior. Am. J. Surg. Pathol. 16:687-93
-
(1992)
Am. J. Surg. Pathol
, vol.16
, pp. 687-693
-
-
Giangaspero, F.1
Rigobello, L.2
Badiali, M.3
Loda, M.4
Andreini, L.5
-
17
-
-
0037604509
-
Morphophenotypic variation predicts clinical behavior in childhood nondesmoplastic medulloblastomas
-
McManamy CS, Lamont JM, Taylor RE, Cole M, Pearson AD, et al. 2003. Morphophenotypic variation predicts clinical behavior in childhood nondesmoplastic medulloblastomas. J. Neuropathol. Exp. Neurol. 62:627-32
-
(2003)
J. Neuropathol. Exp. Neurol
, vol.62
, pp. 627-632
-
-
McManamy, C.S.1
Lamont, J.M.2
Taylor, R.E.3
Cole, M.4
Pearson, A.D.5
-
18
-
-
0030968658
-
Mitotic percentage index: A new prognostic factor for childhood medulloblastoma
-
Gilbertson RJ, Jaros E, Perry RH, Kelly PJ, Lunec J, et al. 1997. Mitotic percentage index: a new prognostic factor for childhood medulloblastoma. Eur. J. Cancer 33:609-15
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 609-615
-
-
Gilbertson, R.J.1
Jaros, E.2
Perry, R.H.3
Kelly, P.J.4
Lunec, J.5
-
19
-
-
0032728334
-
Medulloblastoma with extensive nodularity: A variant with favorable prognosis
-
Giangaspero F, Perilongo G, Fondelli MP, Brisigotti M, Carollo C, et al. 1999. Medulloblastoma with extensive nodularity: a variant with favorable prognosis. J. Neurosurg. 91:971-77
-
(1999)
J. Neurosurg
, vol.91
, pp. 971-977
-
-
Giangaspero, F.1
Perilongo, G.2
Fondelli, M.P.3
Brisigotti, M.4
Carollo, C.5
-
20
-
-
0033791188
-
Large cell/anaplastic medulloblastomas: A Pediatric Oncology Group Study
-
Brown HG, Kepner JL, Perlman EJ, Friedman HS, Strother DR, et al. 2000. "Large cell/anaplastic" medulloblastomas: a Pediatric Oncology Group Study. J. Neuropathol. Exp. Neurol. 59:857-65
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 857-865
-
-
Brown, H.G.1
Kepner, J.L.2
Perlman, E.J.3
Friedman, H.S.4
Strother, D.R.5
-
21
-
-
0037080303
-
Histopathologic grading of medulloblastomas: A Pediatric Oncology Group study
-
Eberhart CG, Kepner JL, Goldthwaite PT, Kun LE, Duffner PK, et al. 2002. Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study. Cancer 94:552-60
-
(2002)
Cancer
, vol.94
, pp. 552-560
-
-
Eberhart, C.G.1
Kepner, J.L.2
Goldthwaite, P.T.3
Kun, L.E.4
Duffner, P.K.5
-
22
-
-
0036204622
-
Paediatric embryonic brain tumours. Biological and clinical relevance of molecular genetic abnormalities
-
Gilbertson R. 2002. Paediatric embryonic brain tumours. Biological and clinical relevance of molecular genetic abnormalities. Eur. J. Cancer 38:675-85
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 675-685
-
-
Gilbertson, R.1
-
23
-
-
0034027968
-
Cytogenetic and molecular genetic abnormalities in primitive neuroectodermal tumors of the central nervous system
-
Goussia AC, Bruner JM, Kyritsis AP, Agnantis NJ, Fuller GN. 2000. Cytogenetic and molecular genetic abnormalities in primitive neuroectodermal tumors of the central nervous system. Anticancer Res. 20:65-73
-
(2000)
Anticancer Res
, vol.20
, pp. 65-73
-
-
Goussia, A.C.1
Bruner, J.M.2
Kyritsis, A.P.3
Agnantis, N.J.4
Fuller, G.N.5
-
24
-
-
0023831581
-
Chromosome abnormalities in pediatric brain tumors
-
Griffin CA, Hawkins AL, Packer RJ, Rorke LB, Emanuel BS. 1988. Chromosome abnormalities in pediatric brain tumors. Cancer Res. 48:175-80
-
(1988)
Cancer Res
, vol.48
, pp. 175-180
-
-
Griffin, C.A.1
Hawkins, A.L.2
Packer, R.J.3
Rorke, L.B.4
Emanuel, B.S.5
-
25
-
-
0035445646
-
Clinical and molecular stratification of disease risk in medulloblastoma
-
Gilbertson R, Wickramasinghe C, Hernan R, Balaji V, Hunt D, et al. 2001. Clinical and molecular stratification of disease risk in medulloblastoma. Br. J. Cancer 85:705-12
-
(2001)
Br. J. Cancer
, vol.85
, pp. 705-712
-
-
Gilbertson, R.1
Wickramasinghe, C.2
Hernan, R.3
Balaji, V.4
Hunt, D.5
-
26
-
-
4143081483
-
Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients
-
Lamont JM, McManamy CS, Pearson AD, Clifford SC, Ellison DW. 2004. Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients. Clin. Cancer Res. 10:5482-93
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 5482-5493
-
-
Lamont, J.M.1
McManamy, C.S.2
Pearson, A.D.3
Clifford, S.C.4
Ellison, D.W.5
-
27
-
-
0034865073
-
Large cell/anaplastic medulloblastomas and medullomyoblastomas: Clinicopathological and genetic features
-
Leonard JR, Cai DX, Rivet DJ, Kaufman BA, Park TS, et al. 2001. Large cell/anaplastic medulloblastomas and medullomyoblastomas: clinicopathological and genetic features. J. Neurosurg. 95:82-88
-
(2001)
J. Neurosurg
, vol.95
, pp. 82-88
-
-
Leonard, J.R.1
Cai, D.X.2
Rivet, D.J.3
Kaufman, B.A.4
Park, T.S.5
-
28
-
-
0032987525
-
Comparative genomic hybridization and histological variation in primitive neuroectodermal tumours
-
Nicholson JC, Ross FM, Kohler JA, Ellison DW. 1999. Comparative genomic hybridization and histological variation in primitive neuroectodermal tumours. Br. J. Cancer 80:1322-31
-
(1999)
Br. J. Cancer
, vol.80
, pp. 1322-1331
-
-
Nicholson, J.C.1
Ross, F.M.2
Kohler, J.A.3
Ellison, D.W.4
-
29
-
-
33646362581
-
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
-
Thompson MC, Fuller C, Hogg TL, Dalton J, Finkelstein D, et al. 2006. Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J. Clin. Oncol. 24:1924-31
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 1924-1931
-
-
Thompson, M.C.1
Fuller, C.2
Hogg, T.L.3
Dalton, J.4
Finkelstein, D.5
-
30
-
-
0029031125
-
Prognostic implications of chromosome 17p deletions in human medulloblastomas
-
Batra SK, McLendon RE, Koo JS, Castelino-Prabhu S, Fuchs HE, et al. 1995. Prognostic implications of chromosome 17p deletions in human medulloblastomas. J. Neuro Oncol. 24:39-45
-
(1995)
J. Neuro Oncol
, vol.24
, pp. 39-45
-
-
Batra, S.K.1
McLendon, R.E.2
Koo, J.S.3
Castelino-Prabhu, S.4
Fuchs, H.E.5
-
31
-
-
0026378708
-
Prognostic significance of molecular genetic markers in childhood brain tumors
-
Cogen PH. 1991. Prognostic significance of molecular genetic markers in childhood brain tumors. Pediatr. Neurosurg. 17:245-50
-
(1991)
Pediatr. Neurosurg
, vol.17
, pp. 245-250
-
-
Cogen, P.H.1
-
32
-
-
0031803734
-
Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome
-
Scheurlen WG, Schwabe GC, Joos S, Mollenhauer J, Sorensen N, et al. 1998. Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. J. Clin. Oncol. 16:2478-85
-
(1998)
J. Clin. Oncol
, vol.16
, pp. 2478-2485
-
-
Scheurlen, W.G.1
Schwabe, G.C.2
Joos, S.3
Mollenhauer, J.4
Sorensen, N.5
-
33
-
-
33751234205
-
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular subgroup of medulloblastomas associated with a favorable prognosis
-
Clifford SC, Lusher ME, Lindsey JC, Langdon JA, Gilbertson RJ, et al. 2006. Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular subgroup of medulloblastomas associated with a favorable prognosis. Cell Cycle 5:2666-70
-
(2006)
Cell Cycle
, vol.5
, pp. 2666-2670
-
-
Clifford, S.C.1
Lusher, M.E.2
Lindsey, J.C.3
Langdon, J.A.4
Gilbertson, R.J.5
-
34
-
-
32944461274
-
β-Catenin status predicts a favorable outcome in childhood medulloblastoma
-
Ellison DW, Onilude OE, Lindsey JC, Lusher ME, Weston CL, et al. 2005. β-Catenin status predicts a favorable outcome in childhood medulloblastoma. J. Clin. Oncol. 23:7951-57
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 7951-7957
-
-
Ellison, D.W.1
Onilude, O.E.2
Lindsey, J.C.3
Lusher, M.E.4
Weston, C.L.5
-
35
-
-
33749044182
-
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): Long-term results from a prospective, multicentre trial
-
Gajjar A, Chintagumpala M, Ashley D, Kellie S, Kun LE, et al. 2006. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol. 7:813-20
-
(2006)
Lancet Oncol
, vol.7
, pp. 813-820
-
-
Gajjar, A.1
Chintagumpala, M.2
Ashley, D.3
Kellie, S.4
Kun, L.E.5
-
36
-
-
0028798253
-
Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas
-
Schofield D, West DC, Anthony DC, Marshal R, Sklar J. 1995. Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas. Am. J. Pathol. 146:472-80
-
(1995)
Am. J. Pathol
, vol.146
, pp. 472-480
-
-
Schofield, D.1
West, D.C.2
Anthony, D.C.3
Marshal, R.4
Sklar, J.5
-
37
-
-
31544466779
-
c-myc overexpression causes anaplasia in medulloblastoma
-
Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, et al. 2006. c-myc overexpression causes anaplasia in medulloblastoma. Cancer Res. 66:673-81
-
(2006)
Cancer Res
, vol.66
, pp. 673-681
-
-
Stearns, D.1
Chaudhry, A.2
Abel, T.W.3
Burger, P.C.4
Dang, C.V.5
-
38
-
-
0003170636
-
Neurocytoma or neuroblastoma, a kind of tumour not generally recognised
-
Wright JS. 1910. Neurocytoma or neuroblastoma, a kind of tumour not generally recognised. J. Exp. Med. 12:556-61
-
(1910)
J. Exp. Med
, vol.12
, pp. 556-561
-
-
Wright, J.S.1
-
39
-
-
0000030724
-
An autoradiographic analysis of histogenesis in the mouse cerebellum
-
Miale IL, Sidman RL. 1961. An autoradiographic analysis of histogenesis in the mouse cerebellum. Exp. Neurol. 4:277-96
-
(1961)
Exp. Neurol
, vol.4
, pp. 277-296
-
-
Miale, I.L.1
Sidman, R.L.2
-
40
-
-
33644998123
-
Development of the deep cerebellar nuclei: Transcription factors and cell migration from the rhombic lip
-
Fink AJ, Englund C, Daza RA, Pham D, Lau C, et al. 2006. Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J. Neurosci. 26:3066-76
-
(2006)
J. Neurosci
, vol.26
, pp. 3066-3076
-
-
Fink, A.J.1
Englund, C.2
Daza, R.A.3
Pham, D.4
Lau, C.5
-
41
-
-
0021967883
-
Embryonic development of the rat cerebellum. I. Delineation of the cerebellar primordium and early cell movements
-
Altman J, Bayer SA. 1985. Embryonic development of the rat cerebellum. I. Delineation of the cerebellar primordium and early cell movements. J. Comp. Neurol. 231:1-26
-
(1985)
J. Comp. Neurol
, vol.231
, pp. 1-26
-
-
Altman, J.1
Bayer, S.A.2
-
42
-
-
0033566108
-
Biphasic dispersion of clones containing Purkinje cells and glia in the developing chick cerebellum
-
Lin JC, Cepko CL. 1999. Biphasic dispersion of clones containing Purkinje cells and glia in the developing chick cerebellum. Dev. Biol. 211:177-97
-
(1999)
Dev. Biol
, vol.211
, pp. 177-197
-
-
Lin, J.C.1
Cepko, C.L.2
-
43
-
-
0030729233
-
Retrospective clonal analysis of the cerebellum using genetic laacZ/lacZ mouse mosaics
-
Mathis L, Bonnerot C, Puelles L, Nicolas JF. 1997. Retrospective clonal analysis of the cerebellum using genetic laacZ/lacZ mouse mosaics. Development 124:4089-104
-
(1997)
Development
, vol.124
, pp. 4089-4104
-
-
Mathis, L.1
Bonnerot, C.2
Puelles, L.3
Nicolas, J.F.4
-
44
-
-
33751348770
-
Molecular markers of neuronal progenitors in the embryonic cerebellar anlage
-
Morales D, Hatten ME. 2006. Molecular markers of neuronal progenitors in the embryonic cerebellar anlage. J. Neurosci. 26:12226-36
-
(2006)
J. Neurosci
, vol.26
, pp. 12226-12236
-
-
Morales, D.1
Hatten, M.E.2
-
45
-
-
0030025016
-
Generation of cerebellar interneurons from dividing progenitors in white matter
-
Zhang L, Goldman JE. 1996. Generation of cerebellar interneurons from dividing progenitors in white matter. Neuron 16:47-54
-
(1996)
Neuron
, vol.16
, pp. 47-54
-
-
Zhang, L.1
Goldman, J.E.2
-
46
-
-
22844437215
-
Isolation of neural stem cells from the postnatal cerebellum
-
Lee A, Kessler JD, Read TA, Kaiser C, Corbeil D, et al. 2005. Isolation of neural stem cells from the postnatal cerebellum. Nat. Neurosci. 8:723-29
-
(2005)
Nat. Neurosci
, vol.8
, pp. 723-729
-
-
Lee, A.1
Kessler, J.D.2
Read, T.A.3
Kaiser, C.4
Corbeil, D.5
-
47
-
-
0033363492
-
Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells
-
Alder J, Lee KJ, Jessell TM, Hatten ME. 1999. Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells. Nat. Neurosci. 2:535-40
-
(1999)
Nat. Neurosci
, vol.2
, pp. 535-540
-
-
Alder, J.1
Lee, K.J.2
Jessell, T.M.3
Hatten, M.E.4
-
48
-
-
0032796826
-
Sonic hedgehog regulates the growth and patterning of the cerebellum
-
Dahmane N, Ruiz-i-Altaba A. 1999. Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 126:3089-100
-
(1999)
Development
, vol.126
, pp. 3089-3100
-
-
Dahmane, N.1
Ruiz-i-Altaba, A.2
-
49
-
-
2942530769
-
Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum
-
Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP. 2004. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev. Biol. 270:393-410
-
(2004)
Dev. Biol
, vol.270
, pp. 393-410
-
-
Lewis, P.M.1
Gritli-Linde, A.2
Smeyne, R.3
Kottmann, A.4
McMahon, A.P.5
-
51
-
-
0037232580
-
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
-
Kenney AM, Cole MD, Rowitch DH. 2003. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 130:15-28
-
(2003)
Development
, vol.130
, pp. 15-28
-
-
Kenney, A.M.1
Cole, M.D.2
Rowitch, D.H.3
-
52
-
-
0038132179
-
Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors
-
Oliver TG, Grasfeder LL, Carroll AL, Kaiser C, Gillingham CL, et al. 2003. Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors. Proc. Natl. Acad. Sci. USA 100:7331-36
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7331-7336
-
-
Oliver, T.G.1
Grasfeder, L.L.2
Carroll, A.L.3
Kaiser, C.4
Gillingham, C.L.5
-
53
-
-
1642474000
-
Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors
-
Kenney AM, Widlund HR, Rowitch DH. 2004. Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors. Development 131:217-28
-
(2004)
Development
, vol.131
, pp. 217-228
-
-
Kenney, A.M.1
Widlund, H.R.2
Rowitch, D.H.3
-
54
-
-
24144441250
-
The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors
-
Sjostrom SK, Finn G, Hahn WC, Rowitch DH, Kenney AM. 2005. The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors. Dev. Cell 9:327-38
-
(2005)
Dev. Cell
, vol.9
, pp. 327-338
-
-
Sjostrom, S.K.1
Finn, G.2
Hahn, W.C.3
Rowitch, D.H.4
Kenney, A.M.5
-
55
-
-
33645220566
-
Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling
-
Riobo NA, Lu K, Ai X, Haines GM, Emerson CP Jr. 2006. Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling. Proc. Natl. Acad. Sci. USA 103:4505-10
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 4505-4510
-
-
Riobo, N.A.1
Lu, K.2
Ai, X.3
Haines, G.M.4
Emerson Jr., C.P.5
-
56
-
-
33847314199
-
Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells
-
Fogarty MP, Emmenegger BA, Grasfeder LL, Oliver TG, Wechsler-Reya RJ. 2007. Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells. Proc. Natl. Acad. Sci. USA. 104:2973-78
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 2973-2978
-
-
Fogarty, M.P.1
Emmenegger, B.A.2
Grasfeder, L.L.3
Oliver, T.G.4
Wechsler-Reya, R.J.5
-
57
-
-
0032959871
-
Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
-
Wechsler-Reya RJ, Scott MP. 1999. Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 22:103-14
-
(1999)
Neuron
, vol.22
, pp. 103-114
-
-
Wechsler-Reya, R.J.1
Scott, M.P.2
-
58
-
-
4043147087
-
Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling
-
Rios I, Alvarez-Rodriguez R, Marti E, Pons S. 2004. Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling. Development 131:3159-68
-
(2004)
Development
, vol.131
, pp. 3159-3168
-
-
Rios, I.1
Alvarez-Rodriguez, R.2
Marti, E.3
Pons, S.4
-
59
-
-
22844440114
-
Notch signaling in the mammalian central nervous system: Insights from mouse mutants
-
Yoon K, Gaiano N. 2005. Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nat. Neurosci. 8:709-15
-
(2005)
Nat. Neurosci
, vol.8
, pp. 709-715
-
-
Yoon, K.1
Gaiano, N.2
-
60
-
-
0036897569
-
Asymmetric segregation of Numb: A mechanism for neural specification from Drosophila to mammals
-
Cayouette M, Raff M. 2002. Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals. Nat. Neurosci. 5:1265-69
-
(2002)
Nat. Neurosci
, vol.5
, pp. 1265-1269
-
-
Cayouette, M.1
Raff, M.2
-
61
-
-
0037154292
-
Protein degradation: Four E3s for the notch pathway
-
Lai EC. 2002. Protein degradation: four E3s for the notch pathway. Curr. Biol. 12: R74-78
-
(2002)
Curr. Biol
, vol.12
-
-
Lai, E.C.1
-
62
-
-
0035974898
-
Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation
-
Solecki DJ, Liu XL, Tomoda T, Fang Y, Hatten ME. 2001. Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron 31:557-68
-
(2001)
Neuron
, vol.31
, pp. 557-568
-
-
Solecki, D.J.1
Liu, X.L.2
Tomoda, T.3
Fang, Y.4
Hatten, M.E.5
-
63
-
-
0347722279
-
Murine numb regulates granule cell maturation in the cerebellum
-
Klein AL, Zilian O, Suter U, Taylor V. 2004. Murine numb regulates granule cell maturation in the cerebellum. Dev. Biol. 266:161-77
-
(2004)
Dev. Biol
, vol.266
, pp. 161-177
-
-
Klein, A.L.1
Zilian, O.2
Suter, U.3
Taylor, V.4
-
64
-
-
33751503224
-
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination
-
Di Marcotullio L, Ferretti E, Greco A, De Smaele E, Po A, et al. 2006. Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination. Nat. Cell Biol. 8:1415-23
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 1415-1423
-
-
Di Marcotullio, L.1
Ferretti, E.2
Greco, A.3
De Smaele, E.4
Po, A.5
-
65
-
-
0036023380
-
Notch1 is required for neuronal and glial differentiation in the cerebellum
-
Lutolf S, Radtke F, Aguet M, Suter U, Taylor V. 2002. Notch1 is required for neuronal and glial differentiation in the cerebellum. Development 129:373-85
-
(2002)
Development
, vol.129
, pp. 373-385
-
-
Lutolf, S.1
Radtke, F.2
Aguet, M.3
Suter, U.4
Taylor, V.5
-
66
-
-
0037218819
-
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
-
Lai K, Kaspar BK, Gage FH, Schaffer DV. 2003. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat. Neurosci. 6:21-27
-
(2003)
Nat. Neurosci
, vol.6
, pp. 21-27
-
-
Lai, K.1
Kaspar, B.K.2
Gage, F.H.3
Schaffer, D.V.4
-
67
-
-
10744230965
-
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
-
Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, et al. 2003. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39:937-50
-
(2003)
Neuron
, vol.39
, pp. 937-950
-
-
Machold, R.1
Hayashi, S.2
Rutlin, M.3
Muzumdar, M.D.4
Nery, S.5
-
68
-
-
13344282140
-
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
-
Palma V, Lim DA, Dahmane N, Sanchez P, Brionne TC, et al. 2005. Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development 132:335-44
-
(2005)
Development
, vol.132
, pp. 335-344
-
-
Palma, V.1
Lim, D.A.2
Dahmane, N.3
Sanchez, P.4
Brionne, T.C.5
-
69
-
-
17844366846
-
WNTs in the vertebrate nervous system: From patterning to neuronal connectivity
-
Ciani L, Salinas PC. 2005. WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat. Rev. Neurosci. 6:351-62
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 351-362
-
-
Ciani, L.1
Salinas, P.C.2
-
70
-
-
0036747385
-
The ins and outs of APC and β-catenin nuclear transport
-
3:834-39
-
Henderson BR, Fagotto F. 2002. The ins and outs of APC and β-catenin nuclear transport. EMBO Rep. 3:834-39
-
(2002)
EMBO Rep
-
-
Henderson, B.R.1
Fagotto, F.2
-
71
-
-
0025188130
-
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
-
McMahon AP, Bradley A. 1990. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62:1073-85
-
(1990)
Cell
, vol.62
, pp. 1073-1085
-
-
McMahon, A.P.1
Bradley, A.2
-
72
-
-
0025074908
-
Targeted disruption of the murine int-1 protooncogene resulting in severe abnormalities in midbrain and cerebellar development
-
Thomas KR, Capecchi MR. 1990. Targeted disruption of the murine int-1 protooncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346:847-50
-
(1990)
Nature
, vol.346
, pp. 847-850
-
-
Thomas, K.R.1
Capecchi, M.R.2
-
73
-
-
33646045010
-
Stem cells and cancer: Two faces of Eve
-
Clarke MF, Fuller M. 2006. Stem cells and cancer: two faces of Eve. Cell 124:1111-15
-
(2006)
Cell
, vol.124
, pp. 1111-1115
-
-
Clarke, M.F.1
Fuller, M.2
-
74
-
-
0345059767
-
Applying the principles of stem-cell biology to cancer
-
Pardal R, Clarke MF, Morrison SJ. 2003. Applying the principles of stem-cell biology to cancer. Nat. Rev. Cancer 3:895-902
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 895-902
-
-
Pardal, R.1
Clarke, M.F.2
Morrison, S.J.3
-
75
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. 1997. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3:730-37
-
(1997)
Nat. Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
76
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, et al. 2003. Cancerous stem cells can arise from pediatric brain tumors. Proc. Natl. Acad. Sci. USA 100:15178-83
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
Masterman-Smith, M.4
Geschwind, D.H.5
-
77
-
-
0036737914
-
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
-
Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, et al. 2002. Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39:193-206
-
(2002)
Glia
, vol.39
, pp. 193-206
-
-
Ignatova, T.N.1
Kukekov, V.G.2
Laywell, E.D.3
Suslov, O.N.4
Vrionis, F.D.5
-
78
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, et al. 1994. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367:645-48
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
-
79
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, et al. 2004. Identification of human brain tumour initiating cells. Nature 432:396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
-
80
-
-
26644435531
-
Radial glia cells are candidate stem cells of ependymoma
-
Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, et al. 2005. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8:323-35
-
(2005)
Cancer Cell
, vol.8
, pp. 323-335
-
-
Taylor, M.D.1
Poppleton, H.2
Fuller, C.3
Su, X.4
Liu, Y.5
-
81
-
-
33750313208
-
Cancer stem cells: Perspectives on current status and future directions: AACR Workshop on Cancer Stem Cells
-
Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, et al. 2006. Cancer stem cells: perspectives on current status and future directions: AACR Workshop on Cancer Stem Cells. Cancer Res. 66:9339-44
-
(2006)
Cancer Res
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Jamieson, C.H.5
-
82
-
-
0034687840
-
Direct isolation of human central nervous system stem cells
-
Uchida N, Buck DW, He D, Reitsma MJ, Masek M, et al. 2000. Direct isolation of human central nervous system stem cells. Proc. Natl. Acad. Sci. USA 97:14720-25
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14720-14725
-
-
Uchida, N.1
Buck, D.W.2
He, D.3
Reitsma, M.J.4
Masek, M.5
-
83
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, et al. 2007. A perivascular niche for brain tumor stem cells. Cancer Cell 11:69-82
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
-
84
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, et al. 2002. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 1:269-77
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
Sharpless, N.E.4
Chan, S.S.5
-
85
-
-
33746498580
-
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, et al. 2006. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 442:818-22
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
Stubbs, M.C.4
Wang, Y.5
-
86
-
-
33847068802
-
Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin
-
Sharma MK, Mansur DB, Reifenberger G, Perry A, Leonard JR, et al. 2007. Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin. Cancer Res. 67:890-900
-
(2007)
Cancer Res
, vol.67
, pp. 890-900
-
-
Sharma, M.K.1
Mansur, D.B.2
Reifenberger, G.3
Perry, A.4
Leonard, J.R.5
-
87
-
-
0034017036
-
Expression of the neurotrophin receptor p75NTR in medulloblastomas is correlated with distinct histological and clinical features: Evidence for a medulloblastoma subtype derived from the external granule cell layer
-
Buhren J, Christoph AH, Buslei R, Albrecht S, Wiestler OD, et al. 2000. Expression of the neurotrophin receptor p75NTR in medulloblastomas is correlated with distinct histological and clinical features: evidence for a medulloblastoma subtype derived from the external granule cell layer. J. Neuropathol. Exp. Neurol. 59:229-40
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 229-240
-
-
Buhren, J.1
Christoph, A.H.2
Buslei, R.3
Albrecht, S.4
Wiestler, O.D.5
-
89
-
-
5644266355
-
Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma subtypes
-
Salsano E, Pollo B, Eoli M, Giordana MT, Finocchiaro G. 2004. Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma subtypes. Neurosci. Lett. 370:180-85
-
(2004)
Neurosci. Lett
, vol.370
, pp. 180-185
-
-
Salsano, E.1
Pollo, B.2
Eoli, M.3
Giordana, M.T.4
Finocchiaro, G.5
-
90
-
-
0030066459
-
Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma
-
Yokota N, Aruga J, Takai S, Yamada K, Hamazaki M, et al. 1996. Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma. Cancer Res. 56:377-83
-
(1996)
Cancer Res
, vol.56
, pp. 377-383
-
-
Yokota, N.1
Aruga, J.2
Takai, S.3
Yamada, K.4
Hamazaki, M.5
-
91
-
-
0026627965
-
Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9
-
Gailani MR, Bale SJ, Leffell DJ, DiGiovanna JJ, Peck GL, et al. 1992. Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9. Cell 69:111-17
-
(1992)
Cell
, vol.69
, pp. 111-117
-
-
Gailani, M.R.1
Bale, S.J.2
Leffell, D.J.3
DiGiovanna, J.J.4
Peck, G.L.5
-
92
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, et al. 1996. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85:841-51
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
Gailani, M.R.4
Shanley, S.5
-
93
-
-
0031002840
-
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome
-
Kimonis VE, Goldstein AM, Pastakia B, Yang ML, Kase R, et al. 1997. Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome. Am. J. Med. Genet. 69:299-308
-
(1997)
Am. J. Med. Genet
, vol.69
, pp. 299-308
-
-
Kimonis, V.E.1
Goldstein, A.M.2
Pastakia, B.3
Yang, M.L.4
Kase, R.5
-
94
-
-
0030913169
-
Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched
-
Pietsch T, Waha A, Koch A, Kraus J, Albrecht S, et al. 1997. Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res. 57:2085-88
-
(1997)
Cancer Res
, vol.57
, pp. 2085-2088
-
-
Pietsch, T.1
Waha, A.2
Koch, A.3
Kraus, J.4
Albrecht, S.5
-
95
-
-
0031036694
-
Sporadic medulloblastomas contain PTCH mutations
-
Raffel C, Jenkins RB, Frederick L, Hebrink D, Alderete B, et al. 1997. Sporadic medulloblastomas contain PTCH mutations. Cancer Res. 57:842-45
-
(1997)
Cancer Res
, vol.57
, pp. 842-845
-
-
Raffel, C.1
Jenkins, R.B.2
Frederick, L.3
Hebrink, D.4
Alderete, B.5
-
96
-
-
0030874617
-
Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours
-
Vorechovsky I, Tingby O, Hartman M, Stromberg B, Nister M, et al. 1997. Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours. Oncogene 15:361-66
-
(1997)
Oncogene
, vol.15
, pp. 361-366
-
-
Vorechovsky, I.1
Tingby, O.2
Hartman, M.3
Stromberg, B.4
Nister, M.5
-
97
-
-
0030738693
-
Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system
-
Wolter M, Reifenberger J, Sommer C, Ruzicka T, Reifenberger G. 1997. Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res. 57:2581-85
-
(1997)
Cancer Res
, vol.57
, pp. 2581-2585
-
-
Wolter, M.1
Reifenberger, J.2
Sommer, C.3
Ruzicka, T.4
Reifenberger, G.5
-
98
-
-
15644373337
-
Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors
-
Xie J, Johnson RL, Zhang X, Bare JW, Waldman FM, et al. 1997. Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors. Cancer Res. 57:2369-72
-
(1997)
Cancer Res
, vol.57
, pp. 2369-2372
-
-
Xie, J.1
Johnson, R.L.2
Zhang, X.3
Bare, J.W.4
Waldman, F.M.5
-
99
-
-
0033990220
-
Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma
-
Zurawel RH, Allen C, Chiappa S, Cato W, Biegel J, et al. 2000. Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma. Genes Chromos. Cancer 27:44-51
-
(2000)
Genes Chromos. Cancer
, vol.27
, pp. 44-51
-
-
Zurawel, R.H.1
Allen, C.2
Chiappa, S.3
Cato, W.4
Biegel, J.5
-
100
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse patched mutants
-
Goodrich LV, Milenkovic L, Higgins KM, Scott MP. 1997. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277:1109-13
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenkovic, L.2
Higgins, K.M.3
Scott, M.P.4
-
101
-
-
0141816821
-
A molecular fingerprint for medulloblastoma
-
Lee Y, Miller HL, Jensen P, Hernan R, Connelly M, et al. 2003. A molecular fingerprint for medulloblastoma. Cancer Res. 63:5428-37
-
(2003)
Cancer Res
, vol.63
, pp. 5428-5437
-
-
Lee, Y.1
Miller, H.L.2
Jensen, P.3
Hernan, R.4
Connelly, M.5
-
102
-
-
31744451535
-
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
-
Svard J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, et al. 2006. Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev. Cell 10:187-97
-
(2006)
Dev. Cell
, vol.10
, pp. 187-197
-
-
Svard, J.1
Heby-Henricson, K.2
Persson-Lek, M.3
Rozell, B.4
Lauth, M.5
-
103
-
-
0036648241
-
Mutations in SUFU predispose to medulloblastoma
-
Taylor MD, Liu L, Raffel C, Hui CC, Mainprize TG, et al. 2002. Mutations in SUFU predispose to medulloblastoma. Nat. Genet. 31:306-10
-
(2002)
Nat. Genet
, vol.31
, pp. 306-310
-
-
Taylor, M.D.1
Liu, L.2
Raffel, C.3
Hui, C.C.4
Mainprize, T.G.5
-
104
-
-
7044233735
-
No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours
-
Koch A, Waha A, Hartmann W, Milde U, Goodyer CG, et al. 2004. No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours. Neuropathol. Appl. Neurobiol. 30:532-39
-
(2004)
Neuropathol. Appl. Neurobiol
, vol.30
, pp. 532-539
-
-
Koch, A.1
Waha, A.2
Hartmann, W.3
Milde, U.4
Goodyer, C.G.5
-
105
-
-
0032898184
-
Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32
-
Smyth I, Narang MA, Evans T, Heimann C, Nakamura Y, et al. 1999. Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32. Hum. Mol. Genet. 8:291-97
-
(1999)
Hum. Mol. Genet
, vol.8
, pp. 291-297
-
-
Smyth, I.1
Narang, M.A.2
Evans, T.3
Heimann, C.4
Nakamura, Y.5
-
106
-
-
33746879125
-
Patched2 modulates tumorigenesis in patchedl heterozygous mice
-
Lee Y, Miller HL, Russell HR, Boyd K, Curran T, et al. 2006. Patched2 modulates tumorigenesis in patchedl heterozygous mice. Cancer Res. 66:6964-71
-
(2006)
Cancer Res
, vol.66
, pp. 6964-6971
-
-
Lee, Y.1
Miller, H.L.2
Russell, H.R.3
Boyd, K.4
Curran, T.5
-
107
-
-
3242722919
-
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
-
Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, et al. 2004. REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. Proc. Natl. Acad. Sci. USA 101:10833-38
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10833-10838
-
-
Di Marcotullio, L.1
Ferretti, E.2
De Smaele, E.3
Argenti, B.4
Mincione, C.5
-
108
-
-
0142074790
-
Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice
-
Kim JYH, Nelson AL, Algon SA, Graves O, Sturla LM, et al. 2003. Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. Dev. Biol. 263:50-66
-
(2003)
Dev. Biol
, vol.263
, pp. 50-66
-
-
Kim, J.Y.H.1
Nelson, A.L.2
Algon, S.A.3
Graves, O.4
Sturla, L.M.5
-
109
-
-
21044435675
-
Loss of patched and disruption of granule cell development in a preneoplastic stage of medulloblastoma
-
Oliver TG, Read TA, Kessler JD, Mehmeti A, Wells JF, et al. 2005. Loss of patched and disruption of granule cell development in a preneoplastic stage of medulloblastoma. Development 132:2425-39
-
(2005)
Development
, vol.132
, pp. 2425-2439
-
-
Oliver, T.G.1
Read, T.A.2
Kessler, J.D.3
Mehmeti, A.4
Wells, J.F.5
-
110
-
-
0037112420
-
Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1
-
Weiner HL, Bakst R, Hurlbert MS, Ruggiero J, Ahn E, et al. 2002. Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1. Cancer Res. 62:6385-89
-
(2002)
Cancer Res
, vol.62
, pp. 6385-6389
-
-
Weiner, H.L.1
Bakst, R.2
Hurlbert, M.S.3
Ruggiero, J.4
Ahn, E.5
-
111
-
-
7444228699
-
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas
-
Hallahan AR, Pritchard JI, Hansen S, Benson M, Stoeck J, et al. 2004. The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas. Cancer Res. 64:7794-800
-
(2004)
Cancer Res
, vol.64
, pp. 7794-7800
-
-
Hallahan, A.R.1
Pritchard, J.I.2
Hansen, S.3
Benson, M.4
Stoeck, J.5
-
112
-
-
34047263220
-
Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors
-
Zindy F, Uziel T, Ayrault O, Calabrese C, Valentine M, et al. 2007. Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors. Cancer Res. 67:2676-84
-
(2007)
Cancer Res
, vol.67
, pp. 2676-2684
-
-
Zindy, F.1
Uziel, T.2
Ayrault, O.3
Calabrese, C.4
Valentine, M.5
-
113
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
Hamilton SR, Liu B, Parsons RE, Papadopoulos N, Jen J, et al. 1995. The molecular basis of Turcot's syndrome. N. Engl. J. Med. 332:839-47
-
(1995)
N. Engl. J. Med
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
Liu, B.2
Parsons, R.E.3
Papadopoulos, N.4
Jen, J.5
-
114
-
-
33846896438
-
Brain tumors in individuals with familial adenomatous polyposis: A cancer registry experience and pooled case report analysis
-
Attard TM, Giglio P, Koppula S, Snyder C, Lynch HT. 2007. Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis. Cancer 109:761-66
-
(2007)
Cancer
, vol.109
, pp. 761-766
-
-
Attard, T.M.1
Giglio, P.2
Koppula, S.3
Snyder, C.4
Lynch, H.T.5
-
115
-
-
0037473082
-
AXIN1 mutations but not deletions in cerebellar medulloblastomas
-
Baeza N, Masuoka J, Kleihues P, Ohgaki H. 2003. AXIN1 mutations but not deletions in cerebellar medulloblastomas. Oncogene 22:632-36
-
(2003)
Oncogene
, vol.22
, pp. 632-636
-
-
Baeza, N.1
Masuoka, J.2
Kleihues, P.3
Ohgaki, H.4
-
117
-
-
0033883092
-
APC mutations in sporadic medulloblastomas
-
Huang H, Mahler-Araujo BM, Sankila A, Chimelli L, Yonekawa Y, et al. 2000. APC mutations in sporadic medulloblastomas. Am. J. Pathol. 156:433-37
-
(2000)
Am. J. Pathol
, vol.156
, pp. 433-437
-
-
Huang, H.1
Mahler-Araujo, B.M.2
Sankila, A.3
Chimelli, L.4
Yonekawa, Y.5
-
118
-
-
0035427076
-
Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors
-
Koch A, Waha A, Tonn JC, Sorensen N, Berthold F, et al. 2001. Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors. Int. J. Cancer 93:445-49
-
(2001)
Int. J. Cancer
, vol.93
, pp. 445-449
-
-
Koch, A.1
Waha, A.2
Tonn, J.C.3
Sorensen, N.4
Berthold, F.5
-
119
-
-
0037056236
-
Role of Wnt pathway in medulloblastoma oncogenesis
-
Yokota N, Nishizawa S, Ohta S, Date H, Sugimura H, et al. 2002. Role of Wnt pathway in medulloblastoma oncogenesis. Int. J. Cancer 101:198-201
-
(2002)
Int. J. Cancer
, vol.101
, pp. 198-201
-
-
Yokota, N.1
Nishizawa, S.2
Ohta, S.3
Date, H.4
Sugimura, H.5
-
120
-
-
0032030894
-
Sporadic medulloblastomas contain oncogenic β-catenin mutations
-
Zurawel RH, Chiappa SA, Allen C, Raffel C. 1998. Sporadic medulloblastomas contain oncogenic β-catenin mutations. Cancer Res. 58:896-99
-
(1998)
Cancer Res
, vol.58
, pp. 896-899
-
-
Zurawel, R.H.1
Chiappa, S.A.2
Allen, C.3
Raffel, C.4
-
121
-
-
0037011776
-
Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation
-
Kratz JE, Stearns D, Huso DL, Slunt HH, Price DL, et al. 2002. Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation. BMC Cancer 2:33
-
(2002)
BMC Cancer
, vol.2
, pp. 33
-
-
Kratz, J.E.1
Stearns, D.2
Huso, D.L.3
Slunt, H.H.4
Price, D.L.5
-
122
-
-
7444224783
-
Notch1 and notch2 have opposite effects on embryonal brain tumor growth
-
Fan X, Mikolaenko I, Elhassan I, Ni X, Wang Y, et al. 2004. Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Res. 64:7787-93
-
(2004)
Cancer Res
, vol.64
, pp. 7787-7793
-
-
Fan, X.1
Mikolaenko, I.2
Elhassan, I.3
Ni, X.4
Wang, Y.5
-
123
-
-
33747874155
-
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
-
Fan X, Matsui W, Khaki L, Stearns D, Chun J, et al. 2006. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res. 66:7445-52
-
(2006)
Cancer Res
, vol.66
, pp. 7445-7452
-
-
Fan, X.1
Matsui, W.2
Khaki, L.3
Stearns, D.4
Chun, J.5
-
124
-
-
18944390248
-
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
-
Jagtap P, Szabo C. 2005. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat. Rev. Drug Discov. 4:421-40
-
(2005)
Nat. Rev. Drug Discov
, vol.4
, pp. 421-440
-
-
Jagtap, P.1
Szabo, C.2
-
125
-
-
0142054687
-
Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia
-
Offit K, Levran O, Mullaney B, Mah K, Nafa K, et al. 2003. Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia. J. Natl. Cancer Inst. 95:1548-51
-
(2003)
J. Natl. Cancer Inst
, vol.95
, pp. 1548-1551
-
-
Offit, K.1
Levran, O.2
Mullaney, B.3
Mah, K.4
Nafa, K.5
-
126
-
-
0037441757
-
A 20-year perspective on the International Fanconi Anemia Registry (IFAR)
-
Kutler DI, Singh B, Satagopan J, Batish SD, Berwick M, et al. 2003. A 20-year perspective on the International Fanconi Anemia Registry (IFAR). Blood 101:1249-56
-
(2003)
Blood
, vol.101
, pp. 1249-1256
-
-
Kutler, D.I.1
Singh, B.2
Satagopan, J.3
Batish, S.D.4
Berwick, M.5
-
127
-
-
33846569450
-
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
-
Reid S, Schindler D, Hanenberg H, Barker K, Hanks S, et al. 2007. Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat. Genet. 39:162-64
-
(2007)
Nat. Genet
, vol.39
, pp. 162-164
-
-
Reid, S.1
Schindler, D.2
Hanenberg, H.3
Barker, K.4
Hanks, S.5
-
128
-
-
33744481750
-
Molecular pathogenesis of Fanconi anemia: Recent progress
-
Taniguchi T, D'Andrea AD. 2006. Molecular pathogenesis of Fanconi anemia: recent progress. Blood 107:4223-33
-
(2006)
Blood
, vol.107
, pp. 4223-4233
-
-
Taniguchi, T.1
D'Andrea, A.D.2
-
129
-
-
1642315917
-
Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood
-
Hirsch B, Shimamura A, Moreau L, Baidinger S, Hag-alshiekh M, et al. 2004. Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood. Blood 103:2554-59
-
(2004)
Blood
, vol.103
, pp. 2554-2559
-
-
Hirsch, B.1
Shimamura, A.2
Moreau, L.3
Baidinger, S.4
Hag-alshiekh, M.5
-
130
-
-
0037112505
-
DNA ligase FV suppresses medulloblastoma formation
-
Lee Y, McKinnon PJ. 2002. DNA ligase FV suppresses medulloblastoma formation. Cancer Res. 62:6395-99
-
(2002)
Cancer Res
, vol.62
, pp. 6395-6399
-
-
Lee, Y.1
McKinnon, P.J.2
-
132
-
-
33646550838
-
XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice
-
Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, et al. 2006. XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proc. Natl. Acad. Sci USA 103:7378-83
-
(2006)
Proc. Natl. Acad. Sci USA
, vol.103
, pp. 7378-7383
-
-
Yan, C.T.1
Kaushal, D.2
Murphy, M.3
Zhang, Y.4
Datta, A.5
-
133
-
-
31144459985
-
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
-
Bild AH, Yao G, Chang JT, Wang Q, Potti A, et al. 2006. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 439:353-57
-
(2006)
Nature
, vol.439
, pp. 353-357
-
-
Bild, A.H.1
Yao, G.2
Chang, J.T.3
Wang, Q.4
Potti, A.5
-
134
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. 2006. MicroRNA signatures in human cancers. Nat. Rev. Cancer 6:857-66
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
135
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. 2005. MicroRNA expression profiles classify human cancers. Nature 435:834-38
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
-
136
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, et al. 2006. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9:157-73
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
-
137
-
-
33744957443
-
Microarray analysis and tumor classification
-
Quackenbush J. 2006. Microarray analysis and tumor classification. N. Engl. J. Med. 354:2463-72
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 2463-2472
-
-
Quackenbush, J.1
-
138
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, et al. 2003. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc. Natl. Acad. Sci. USA 100:10393-98
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
Korn, E.L.4
Long, P.M.5
-
139
-
-
0034794796
-
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease
-
MacDonald TJ, Brown KM, LaFleur B, Peterson K, Lawlor C, et al. 2001. Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. Nat. Genet. 29:143-52
-
(2001)
Nat. Genet
, vol.29
, pp. 143-152
-
-
MacDonald, T.J.1
Brown, K.M.2
LaFleur, B.3
Peterson, K.4
Lawlor, C.5
-
140
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, et al. 2002. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415:436-42
-
(2002)
Nature
, vol.415
, pp. 436-442
-
-
Pomeroy, S.L.1
Tamayo, P.2
Gaasenbeek, M.3
Sturla, L.M.4
Angelo, M.5
-
141
-
-
33845350493
-
Single nucleotide polymorphism array analysis of cancer
-
Dutt A, Beroukhim R. 2007. Single nucleotide polymorphism array analysis of cancer. Curr. Opin. Oncol. 19:43-49
-
(2007)
Curr. Opin. Oncol
, vol.19
, pp. 43-49
-
-
Dutt, A.1
Beroukhim, R.2
-
142
-
-
33645124451
-
Using high-throughput SNP technologies to study cancer
-
Engle LJ, Simpson CL, Landers JE. 2006. Using high-throughput SNP technologies to study cancer. Oncogene 25:1594-601
-
(2006)
Oncogene
, vol.25
, pp. 1594-1601
-
-
Engle, L.J.1
Simpson, C.L.2
Landers, J.E.3
-
144
-
-
20044384522
-
Mapping of genetic and epigenetic regulatory networks using microarrays
-
van Steensel B. 2005. Mapping of genetic and epigenetic regulatory networks using microarrays. Nat. Genet. 37(Suppl):18-24
-
(2005)
Nat. Genet
, vol.37
, Issue.SUPPL.
, pp. 18-24
-
-
van Steensel, B.1
-
145
-
-
33644853907
-
The colorectal microRNAome
-
Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, et al. 2006. The colorectal microRNAome. Proc. Natl. Acad. Sci. USA 103:3687-92
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3687-3692
-
-
Cummins, J.M.1
He, Y.2
Leary, R.J.3
Pagliarini, R.4
Diaz Jr, L.A.5
|