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Volumn 10, Issue 16, 2004, Pages 5482-5493

Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC MEDULLOBLASTOMA; ARTICLE; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER RISK; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; CHROMOSOME 10Q; CHROMOSOME 17P; CHROMOSOME 9Q; CHROMOSOME ABERRATION; CHROMOSOME LOSS; CLINICAL TRIAL; CYTOGENETICS; DESMOPLASTIC MEDULLOBLASTOMA; GENE; GENE AMPLIFICATION; HIGH RISK POPULATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LARGE CELL MEDULLOBLASTOMA; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MEDULLOBLASTOMA; METASTASIS; MOLECULAR GENETICS; MYCC GENE; MYCN GENE; NODULAR MEDULLOBLASTOMA; ONCOGENE MYC; PATIENT CODING; PRIORITY JOURNAL; PROGNOSIS;

EID: 4143081483     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0721     Document Type: Article
Times cited : (194)

References (41)
  • 1
    • 0032836716 scopus 로고    scopus 로고
    • Posterior fossa medulloblastoma in children and young adults (0-19 years): Survival and performance
    • Helseth E, Due-Tonnessen B, Wesenberg F, Lote K, Lundar T. Posterior fossa medulloblastoma in children and young adults (0-19 years): survival and performance. Childs Nerv Syst 1999;15:451-5.
    • (1999) Childs Nerv Syst , vol.15 , pp. 451-455
    • Helseth, E.1    Due-Tonnessen, B.2    Wesenberg, F.3    Lote, K.4    Lundar, T.5
  • 2
    • 0035407296 scopus 로고    scopus 로고
    • Survival and recurrence factors in adult medulloblastoma: The M.D. Anderson Cancer Center experience from 1978 to 1998
    • Kunschner LJ, Kuttesch J, Hess K, Yung WK. Survival and recurrence factors in adult medulloblastoma: the M.D. Anderson Cancer Center experience from 1978 to 1998. Neurooncology 2001;3:167-73.
    • (2001) Neurooncology , vol.3 , pp. 167-173
    • Kunschner, L.J.1    Kuttesch, J.2    Hess, K.3    Yung, W.K.4
  • 3
    • 0032804331 scopus 로고    scopus 로고
    • Survival and neurodevelopmental outcome of young children with medulloblastoma at St Jude Children's Research Hospital
    • Walter AW, Mulhern RK, Gajjar A, et al. Survival and neurodevelopmental outcome of young children with medulloblastoma at St Jude Children's Research Hospital. J Clin Oncol 1999;17:3720-8.
    • (1999) J Clin Oncol , vol.17 , pp. 3720-3728
    • Walter, A.W.1    Mulhern, R.K.2    Gajjar, A.3
  • 4
    • 0033050817 scopus 로고    scopus 로고
    • Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: Conclusions from the Children's Cancer Group 921 randomized phase III study
    • Zeltzer PM, Boyett JM, Finlay JL, et al. Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study. J Clin Oncol 1999;17:832-45.
    • (1999) J Clin Oncol , vol.17 , pp. 832-845
    • Zeltzer, P.M.1    Boyett, J.M.2    Finlay, J.L.3
  • 5
    • 0029119268 scopus 로고
    • Prospective randomised trial of chemotherapy given before radiotherapy in childhood medulloblastoma. International Society of Paediatric Oncology (SIOP) and the (German) Society of Paediatric Oncology (GPO): SIOP II
    • Bailey CC, Gnekow A, Wellek S, et al. Prospective randomised trial of chemotherapy given before radiotherapy in childhood medulloblastoma. International Society of Paediatric Oncology (SIOP) and the (German) Society of Paediatric Oncology (GPO): SIOP II. Med Pediatr Oncol 1995;25:166-78.
    • (1995) Med Pediatr Oncol , vol.25 , pp. 166-178
    • Bailey, C.C.1    Gnekow, A.2    Wellek, S.3
  • 8
    • 0033791188 scopus 로고    scopus 로고
    • "Large cell/anaplastic" medulloblastomas: A Pediatric Oncology Group Study
    • Brown HG, Kepner JL, Perlman EJ, et al. "Large cell/anaplastic" medulloblastomas: a Pediatric Oncology Group Study. J Neuropathol Exp Neurol 2000;59:857-65.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 857-865
    • Brown, H.G.1    Kepner, J.L.2    Perlman, E.J.3
  • 9
    • 0037080303 scopus 로고    scopus 로고
    • Histopathologic grading of medulloblastomas: A Pediatric Oncology Group study
    • Eberhart CG, Kepner JL, Goldthwaite PT, et al. Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study. Cancer 2002;94:552-60.
    • (2002) Cancer , vol.94 , pp. 552-560
    • Eberhart, C.G.1    Kepner, J.L.2    Goldthwaite, P.T.3
  • 10
    • 0037604509 scopus 로고    scopus 로고
    • Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas
    • McManamy CS, Lamont JM, Taylor RE, et al. Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas. J Neuropathol Exp Neurol 2003;62:627-32.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 627-632
    • McManamy, C.S.1    Lamont, J.M.2    Taylor, R.E.3
  • 11
    • 0041625921 scopus 로고    scopus 로고
    • Anaplasia and grading in medulloblastomas
    • Eberhart CG, Burger PC. Anaplasia and grading in medulloblastomas. Brain Pathol 2003;13:376-85.
    • (2003) Brain Pathol , vol.13 , pp. 376-385
    • Eberhart, C.G.1    Burger, P.C.2
  • 12
    • 0036366824 scopus 로고    scopus 로고
    • Classifying the medulloblastoma: Insights from morphology and molecular genetics
    • Ellison D. Classifying the medulloblastoma: insights from morphology and molecular genetics. Neuropathol Appl Neurobiol 2002;28: 257-82.
    • (2002) Neuropathol Appl Neurobiol , vol.28 , pp. 257-282
    • Ellison, D.1
  • 13
    • 0032728334 scopus 로고    scopus 로고
    • Medulloblastoma with extensive nodularity: A variant with favorable prognosis
    • Giangaspero F, Perilongo G, Fondelli MP, et al. Medulloblastoma with extensive nodularity: a variant with favorable prognosis. J Neurosurg 1999;91:971-7.
    • (1999) J Neurosurg , vol.91 , pp. 971-977
    • Giangaspero, F.1    Perilongo, G.2    Fondelli, M.P.3
  • 14
    • 0029620728 scopus 로고
    • Prognostic factors in adult medulloblastoma. A clinico-pathologic study
    • Giordana MT, Cavalla P, Chio A, et al. Prognostic factors in adult medulloblastoma. A clinico-pathologic study. Tumori 1995;81:338-46.
    • (1995) Tumori , vol.81 , pp. 338-346
    • Giordana, M.T.1    Cavalla, P.2    Chio, A.3
  • 16
    • 0028878530 scopus 로고
    • Staging, scoring and grading of medulloblastoma. A postoperative prognosis predicting system based on the cases of a single institute
    • Sure U, Berghom WJ, Bertalanffy H, et al. Staging, scoring and grading of medulloblastoma. A postoperative prognosis predicting system based on the cases of a single institute. Acta Neurochir (Wien) 1995;132:59-65.
    • (1995) Acta Neurochir (Wien) , vol.132 , pp. 59-65
    • Sure, U.1    Berghom, W.J.2    Bertalanffy, H.3
  • 17
    • 0036245047 scopus 로고    scopus 로고
    • MYCC and MYCN oncogene amplification in medulloblastoma
    • Aldosari N, Bigner SH, Burger PC, et al. MYCC and MYCN oncogene amplification in medulloblastoma. Arch Pathol Lab Med 2002;126:540-4.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 540-544
    • Aldosari, N.1    Bigner, S.H.2    Burger, P.C.3
  • 18
    • 0025891733 scopus 로고
    • N-myc and c-myc oncogenes amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification
    • Badiali M, Pession A, Basso G, et al. N-myc and c-myc oncogenes amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification. Tumori 1991;77:118-21.
    • (1991) Tumori , vol.77 , pp. 118-121
    • Badiali, M.1    Pession, A.2    Basso, G.3
  • 19
    • 0034890563 scopus 로고    scopus 로고
    • MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma
    • Grotzer MA, Hogarty MD, Janss AJ, et al. MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma. Clin Cancer Res 2001;7:2425-33.
    • (2001) Clin Cancer Res , vol.7 , pp. 2425-2433
    • Grotzer, M.A.1    Hogarty, M.D.2    Janss, A.J.3
  • 20
    • 0033801873 scopus 로고    scopus 로고
    • C-MYC expression in medulloblastoma and its prognostic value
    • Herms J, Neidt I, Luscher B, et al. C-MYC expression in medulloblastoma and its prognostic value. Int J Cancer 2000;89:395-402.
    • (2000) Int J Cancer , vol.89 , pp. 395-402
    • Herms, J.1    Neidt, I.2    Luscher, B.3
  • 21
    • 0028316608 scopus 로고
    • Aggressive medulloblastoma with high-level N-myc amplification
    • Tomlinson FH, Jenkins RB, Scheithauer BW, et al. Aggressive medulloblastoma with high-level N-myc amplification. Mayo Clin Proc 1994;69:359-65.
    • (1994) Mayo Clin Proc , vol.69 , pp. 359-365
    • Tomlinson, F.H.1    Jenkins, R.B.2    Scheithauer, B.W.3
  • 22
    • 0029031125 scopus 로고
    • Prognostic implications of chromosome 17p deletions in human medulloblastomas
    • Batra SK, McLendon RE, Koo JS, et al. Prognostic implications of chromosome 17p deletions in human medulloblastomas. J Neurooncol 1995;24:39-45.
    • (1995) J Neurooncol , vol.24 , pp. 39-45
    • Batra, S.K.1    McLendon, R.E.2    Koo, J.S.3
  • 23
    • 0030741967 scopus 로고    scopus 로고
    • Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma
    • Gilbertson RJ, Perry RH, Kelly PJ, Pearson AD, Lunec J. Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma. Cancer Res 1997;57:3272-80.
    • (1997) Cancer Res , vol.57 , pp. 3272-3280
    • Gilbertson, R.J.1    Perry, R.H.2    Kelly, P.J.3    Pearson, A.D.4    Lunec, J.5
  • 24
    • 0035445646 scopus 로고    scopus 로고
    • Clinical and molecular stratification of disease risk in medulloblastoma
    • Gilbertson R, Wickramasinghe C, Heman R, et al. Clinical and molecular stratification of disease risk in medulloblastoma. Br J Cancer 2001;85:705-12.
    • (2001) Br J Cancer , vol.85 , pp. 705-712
    • Gilbertson, R.1    Wickramasinghe, C.2    Heman, R.3
  • 25
    • 0033994659 scopus 로고    scopus 로고
    • TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors
    • Grotzer MA, Janss AJ, Fung K, et al. TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors. J Clin Oncol 2000;18:1027-35.
    • (2000) J Clin Oncol , vol.18 , pp. 1027-1035
    • Grotzer, M.A.1    Janss, A.J.2    Fung, K.3
  • 26
    • 0036132648 scopus 로고    scopus 로고
    • Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas
    • Eberhart CG, Kratz JE, Schuster A, et al. Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas. Brain Pathol 2002;12:36-44.
    • (2002) Brain Pathol , vol.12 , pp. 36-44
    • Eberhart, C.G.1    Kratz, J.E.2    Schuster, A.3
  • 27
    • 0026663357 scopus 로고
    • Large-cell medulloblastomas. A distinct variant with highly aggressive behavior
    • Giangaspero F, Rigobello L, Badiali M, et al. Large-cell medulloblastomas. A distinct variant with highly aggressive behavior. Am J Surg Pathol 1992;16:687-93.
    • (1992) Am J Surg Pathol , vol.16 , pp. 687-693
    • Giangaspero, F.1    Rigobello, L.2    Badiali, M.3
  • 28
    • 0033429115 scopus 로고    scopus 로고
    • Oncogene amplification in medulloblastoma: Analysis of a case by comparative genomic hybridization and fluorescence in situ hybridization
    • Jay V, Squire J, Bayani J, Alkhani AM, Rutka JT, Zielenska M. Oncogene amplification in medulloblastoma: analysis of a case by comparative genomic hybridization and fluorescence in situ hybridization. Pathology 1999;31:337-44.
    • (1999) Pathology , vol.31 , pp. 337-344
    • Jay, V.1    Squire, J.2    Bayani, J.3    Alkhani, A.M.4    Rutka, J.T.5    Zielenska, M.6
  • 29
    • 0030913169 scopus 로고    scopus 로고
    • Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched
    • Pietsch T, Waha A, Koch A, et al. Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res 1997;57:2085-8.
    • (1997) Cancer Res , vol.57 , pp. 2085-2088
    • Pietsch, T.1    Waha, A.2    Koch, A.3
  • 30
    • 0031036694 scopus 로고    scopus 로고
    • Sporadic medulloblastomas contain PTCH mutations
    • Raffel C, Jenkins RB, Frederick L, et al. Sporadic medulloblastomas contain PTCH mutations. Cancer Res 1997;57:842-5.
    • (1997) Cancer Res , vol.57 , pp. 842-845
    • Raffel, C.1    Jenkins, R.B.2    Frederick, L.3
  • 31
    • 0028798253 scopus 로고
    • Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas
    • Schofield D, West DC, Anthony DC, Marshal R, Sklar J. Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas. Am J Pathol 1995;146:472-80.
    • (1995) Am J Pathol , vol.146 , pp. 472-480
    • Schofield, D.1    West, D.C.2    Anthony, D.C.3    Marshal, R.4    Sklar, J.5
  • 32
    • 0036648241 scopus 로고    scopus 로고
    • Mutations in SUFU predispose to medulloblastoma
    • Taylor MD, Liu L, Raffel C, et al. Mutations in SUFU predispose to medulloblastoma. Nat Genet 2002;31:306-10.
    • (2002) Nat Genet , vol.31 , pp. 306-310
    • Taylor, M.D.1    Liu, L.2    Raffel, C.3
  • 33
    • 0037842140 scopus 로고    scopus 로고
    • Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for non-metastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study
    • Taylor RE, Bailey CC, Robinson K, et al. Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for non-metastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study. J Clin Oncol 2003;21:1581-91.
    • (2003) J Clin Oncol , vol.21 , pp. 1581-1591
    • Taylor, R.E.1    Bailey, C.C.2    Robinson, K.3
  • 34
    • 0033669529 scopus 로고    scopus 로고
    • Imbalances of chromosome 17 in medulloblastomas determined by comparative genomic hybridisation and fluorescence in situ hybridisation
    • Nicholson J, Wickramasinghe C, Ross F, Crolla J, Ellison D. Imbalances of chromosome 17 in medulloblastomas determined by comparative genomic hybridisation and fluorescence in situ hybridisation. Mol Pathol 2000;53:313-9.
    • (2000) Mol Pathol , vol.53 , pp. 313-319
    • Nicholson, J.1    Wickramasinghe, C.2    Ross, F.3    Crolla, J.4    Ellison, D.5
  • 35
    • 0031803734 scopus 로고    scopus 로고
    • Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome
    • Scheurlen WG, Schwabe GC, Joos S, Mollenhauer J, Sorensen N, Kuhl J. Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. J Clin Oncol 1998;16:2478-85.
    • (1998) J Clin Oncol , vol.16 , pp. 2478-2485
    • Scheurlen, W.G.1    Schwabe, G.C.2    Joos, S.3    Mollenhauer, J.4    Sorensen, N.5    Kuhl, J.6
  • 37
    • 0025971967 scopus 로고
    • "Desmoplastic" versus "classic" medulloblastoma: Comparison of DNA content, histopathology and differentiation
    • Giangaspero F, Chieco P, Ceccarelli C, et al. "Desmoplastic" versus "classic" medulloblastoma: comparison of DNA content, histopathology and differentiation. Virchows Arch A Pathol Anat Histopathol 1991; 418:207-14.
    • (1991) Virchows Arch A Pathol Anat Histopathol , vol.418 , pp. 207-214
    • Giangaspero, F.1    Chieco, P.2    Ceccarelli, C.3
  • 38
    • 0027508405 scopus 로고
    • Relation of tumor-cell ploidy to survival in children with medulloblastoma
    • Gajjar AJ, Heideman RL, Douglass EC, et al. Relation of tumor-cell ploidy to survival in children with medulloblastoma. J Clin Oncol 1993;11:2211-7.
    • (1993) J Clin Oncol , vol.11 , pp. 2211-2217
    • Gajjar, A.J.1    Heideman, R.L.2    Douglass, E.C.3
  • 39
    • 0027528491 scopus 로고
    • Prognostic factors in medulloblastoma, including DNA ploidy
    • Zerbini C, Gelber RD, Weinberg D, et al. Prognostic factors in medulloblastoma, including DNA ploidy. J Clin Oncol 1993;11: 616-22.
    • (1993) J Clin Oncol , vol.11 , pp. 616-622
    • Zerbini, C.1    Gelber, R.D.2    Weinberg, D.3
  • 40
    • 0028040905 scopus 로고
    • Physical mapping of chromosome 17p13.3 in the region of a putative tumor suppressor gene important in medulloblastoma
    • McDonald JD, Daneshvar L, Willert JR, Matsumura K, Waldman F, Cogen PH. Physical mapping of chromosome 17p13.3 in the region of a putative tumor suppressor gene important in medulloblastoma. Genomics 1994;23:229-32.
    • (1994) Genomics , vol.23 , pp. 229-232
    • McDonald, J.D.1    Daneshvar, L.2    Willert, J.R.3    Matsumura, K.4    Waldman, F.5    Cogen, P.H.6
  • 41
    • 0033849398 scopus 로고    scopus 로고
    • Multiple genomic alterations including N-myc amplification in a primary large cell medulloblastoma
    • Reardon DA, Jenkins JJ, Sublett JE, Burger PC, Kun LK. Multiple genomic alterations including N-myc amplification in a primary large cell medulloblastoma. Pediatr Neurosurg 2000;32:187-91.
    • (2000) Pediatr Neurosurg , vol.32 , pp. 187-191
    • Reardon, D.A.1    Jenkins, J.J.2    Sublett, J.E.3    Burger, P.C.4    Kun, L.K.5


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