Comparative genomic hybridization and histological variation in primitive neuroectodermal tumours

British Journal of Cancer

Volumn 80, Issue 9, 1999, Pages 1322-1331

  Nicholson, J C ^a,b   Ross, F M ^a   Kohler, J A ^b   Ellison, D W ^b  

^a WESSEX REGIONAL GENETICS LABORATORY   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cerebral PNET; Comparative genomic hybridization; Glial fibrillary acidic protein; Isochromosome 17q; Medulloblastoma; Monosomy 22

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BRAIN TUMOR; CHILD; CHROMOSOME 17Q; CHROMOSOME 9Q; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; INFANT; MEDULLOBLASTOMA; NEUROECTODERM TUMOR; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ADULT; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; NEUROECTODERMAL TUMORS, PRIMITIVE; NUCLEIC ACID HYBRIDIZATION;

EID: 0032987525     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690525     Document Type: Article

References (48)

1. Bailey CC, Gnekow A, Wellek S, Jones M, Round C, Brown J, Philips A and Neidhardt MK (1995) Prospective randomised trial of chemotherapy given before radiotherapy in childhood medulloblastoma. International Society of Paediatric Oncology (SIOP) and the (German) Society of Paediatric Oncology (GPO): SIOP H. Med Pediatr Oncol 25: 166-178
2. Batra SK, Rasheed BKA, Bigner SH and Bigner DD (1994) Oncogenes and anti-oncogenes in human central nervous system tumours. Lab Invest 71: 621-637
3. Batra SK, McLendon RE, Koo JS, Castelino-Prabhu S, Fuchs HE, Krischer JP, Friedman HS, Bigner DD and Bigner SH (1995) Prognostic implications of chromosome 17p deletions in human medulloblastomas. J Neurooncol 24: 39-45
4. Bhattacharjee MB, Armstrong DD, Vogel H and Cooley LD (1997) Cytogenetic analysis of 120 primary brain tumours and literature review. Cancer Genet Cytogenet 97: 39-53
5. Biegel JA, Rorke LB, Packer RJ, Sutton LN, Schut L, Bonner K and Emanuel BS (1989) Isochromosome 17q in primitive neuroectodermal tumours of the central nervous system. Genes Chromosomes Cancer 1: 139-147
6. Biegel JA, Rorke LB, Packer RJ and Emanuel BS (1990) Monosomy 22 in rhabdoid or atypical tumours of the brain. J Neurosurg 73: 710-714
7. Biegel JA, Rorke LB, Janss AJ, Sutton LN and Parmiter AH (1995) Isochromosome 17q demonstrated by interphase fluorescence in situ hybridization in primitive neuroectodermal tumours of the central nervous system. Genes Chromosomes Cancer 14: 85-96
8. Bigner SH and Vogelstein B (1990) Cytogenetics and molecular genetics of malignant gliomas and medulloblastoma. Brain Pathol 1: 12-18
9. Bigner SH, McLendon RE, Fuchs H, McKeever PE and Friedman HS (1997) Chromosomal characteristics of childhood brain tumours. Cancer Genet Cytogenet 97: 125-134
10. Blaeker H, Rasheed BKA, McLendon RE, Friedman HS, Batra SK, Fuchs HE and Bigner SH (1996) Microsatellite analysis of childhood brain tumours. Genes Chromosomes Cancer 15: 54-63
11. Brenner M (1994) Structure and transcriptional regulation of the GFAP gene. Brain Pathol 4: 245-257
12. Burnett ME, White EC, Sih S, von Haken MS and Cogen PH (1997) Chromosome arm 17p deletion analysis reveals molecular genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system. Cancer Genet Cytogenet 97: 25-31
13. Choux M, Lena G and Hassoun J (1983) Prognosis and long-term follow-up in patients with medulloblastoma. Clin Neurosurg 30: 246-277
14. Cogen PH, Daneshvar L, Metzger AK and Edwards MSB (1990) Deletion mapping of the medulloblastoma locus on chromosome 17p. Genomics 8: 279-285
15. Ellison DW, Steart PV, Gatter KC and Weller RO (1995) Apoptosis in cerebral astrocytic tumours and its relationship to expression of the Bcl-2 and P53 proteins. Neuropathol Appl Neurobiol 21: 352-361
16. Ellison DW and Love S (Eds) (1998) Embryonal neuroepithelial neoplasms of the CNS. In: Neuropathology, Mosby: London.
17. Emadian SM, McDonald JD, Gerken SC and Fults D (1996) Correlation of chromosome 17p loss with clinical outcome in medulloblastoma. Clin Cancer Res 2: 1559-1564
18. Fazioli F, Minichiello L, Matoska V, Castagnino, Miki T, Wong WT and Di Fiore PP (1993) Eps8, a substrate for the epidermal growth factor receptor kinase, enhanced EGF-dependent mitogenic signals. EMBO J 12: 3799-3508
19. Geyer JR, Zeltzer PM, Boyett JM, Rorke LB, Stanley P, Albright L, Wisoff JH, Milstein JM, Allen JC, Finlay JL, Ayers GD, Shurin SB, Stevens KR and Bleyer WA (1994) Survival of infants with primitive neuroectodermal tumours or malignant ependymomas of the CNS treated with eight drugs in 1 day: a report from the children's cancer group. J Clin Oncol 12: 1607-1615
20. Giangaspero F, Chieco P, Ceccarelli C, Lisignoli G, Pozzuoli R, Gambacorta M, Rossi G and Burger PC (1991) 'Desmoplastic' versus 'classic' medulloblastoma: comparison of DNA content, histopathology and differentiation. Virchows Archiv A Pathol Anal 418: 207-214
21. Gilbertson RJ, Perry RH, Kelly PJ, Pearson ADJ and Lunec J (1997) Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma. Cancer Res 57: 3272-3280
22. Heim S and Mitelman F (1995) Tumours of the nervous system. In: Cancer Cytogenetics: Chromosomal and Molecular Genetic Aberrations of Tumour Cells, 2nd edn, pp. 432-454. Wiley-Liss: New York
23. Hubbard JL, Scheithauer BW, Kispert DB, Carpenter SM, Wick MR and Laws ER Jr (1989) Adult cerebellar medulloblastomas: the pathological, radiographic and clinical disease spectrum. J Neurosurg 70: 536-544
24. ISCN (1995) An International System for Human Cytogenetic Nomenclature, Mitelman F (ed). S Karger: Basel
25. Janss AJ, Yachnis AT, Silber JH, Trojanowski JQ, Lee VM-Y, Sutton LN, Perilongo G, Rorke LB and Phillips PC (1996) Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumours. Ann Neurol 39: 481-489
26. Jaros E, Lunec J, Perry RH, Kelly PJ and Pearson ADJ (1993) p53 overexpression identifies a group of central primitive neuroectodermal tumours with a poor prognosis. Br J Cancer 68: 801-807
27. Kallioniemi O-P, Kallioniemi A, Piper J, Isola J, Waldman FM, Gray JW and Pinkel D (1994) Optimising comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumours. Genes Chromosomes Cancer 10: 231-243
28. Kleihues P, Burger PC and Scheithauer BW (1993) Histological Typing of Tumours of the Central Nervous System. Springer: Berlin
29. Maraziotis T, Perentes E, Karamitopoulo E, Nakagawa Y, Gessaga EC, Probst A and Frankfurter A (1992) Neuron-associated class III b-tubulin isotype, retinal S-antigen, synaptophysin, and glial fibrillary acidic protein in human medulloblastomas: a clinicopathological analysis of 36 cases. Acta Neuropathol 84: 355-363
30. McDonald JD, Daneshvar L, Willert JR, Matsumura K, Waldman F and Cogen PH (1994) Physical mappiug of chromosome 17p13.3 in the region of a putative tumour suppressor gene important medulloblastoma. Genomics 23: 229-232
31. Mertens F, Johansson B and Mitelman F (1994) Isochromosomes in neoplasia. Genes Chromosomes Cancer 10: 221-230
32. Miller SA, Dykes DD and Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215-1215
33. Packer RJ (1995) Brain tumours in children. Curr Opin Ped 7: 64-72
34. Phelan CM, Liu L, Ruttledge MH, Müntzning K, Ridderheim P-A and Collins VP (1995) Chromosomes 17 abnormalities and lack of TP53 mutations in paediatric central nervous system tumours. Hum Genet 96: 684-690
35. Pinkel D, Landegent J, Collins C, Fuscoe J, Segraves R, Lucas J and Gray J (1988) Fluorescence in situ hybridization with human chromosome specific libraries: detection of trisomy 21 and translocations of chromosome 4. Proc Natl Acad Sci USA 85: 9138-9142
36. Reardon DA, Michalkiewicz, Boyett JM, Sublett JE, Entrekin RE, Ragsdale ST, Valentine MB, Behm FG, Li H, Heideman RL, Kun LE, Shapiro DN and Look AT (1997) Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization. Cancer Rev 57: 4042-4047
37. Rorke LB (1997) Atypical teratoid/rhabdoid tumours. In Tumours of the Nervous System, Kleihues P and Cavance WK (eds). pp 110-111. International Agency for Research on Cancer: Lyon
38. Schofield D, West DC, Anthony DC, Marshal R and Sklar J (1995) Correlation of loss of heterozygosity at chromosome 9q with histological sub-type in medulloblastomas. Am J Pathol 146 (2): 472-480
39. Schröck E, Thiel G, Lözanova T, du Manoir S, Meffert M-C, Jauch A, Speicher MR, Nürnberg P, Vogel S, Jänisch W, Donis-Keller H, Ried T, Witkowski R and Cremer T (1994) Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses. Am J Pathol 144: 1203-1218
40. Schütz BR, Scheurlen W, Krauss J, du Manoir S, Joos S, Bentz M and Lichter P (1996) Mapping of chromosomal gains and lossen in primitive neuroectodermal tumours by comparative genomic hybridization. Genes Chromosomes Cancer 16: 196-203
41. Sozzi G, Tornielli S, Tagliabue E, Sard L, Pezella F, Pastorino U, Minoletti F, Pilooti S, Ratcliffe C, Veronese ML, Goldstraw P, Huebner K, Croce CM and Pierotti MA (1997) Absence of Fhit protein in primary lung tumours and cell lines with FHIT gene abnormalities. Cancer Res 57: 5207-5212
42. Tait DM, Thornton Jones H, Bloom HJG, Lemerle J and Morris-Jones P (1990) Adjuvant chemotherapy for medulloblastoma: the first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I). Eur J Cancer 26: 464-469
43. Tomlinson FH, Scheithauer BW and Jenkins RB (1992) Medulloblastoma. II: a pathobiologic overview. J Child Neurol 7: 240-252
44. Vorechovsky I, Tingby O, Hartman M, Strömberg B, Nister M, Collins VP and Toftgärd R (1997) Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours. Oncogene 15: 361-366
45. Wolter M, Reifenberger J, Sommer C, Ruzicka T and Reifenberger G (1997) Mutations in the human homologue of Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumours of the central nervous system. Cancer Res 57: 2581-2585
46. Wong WT, Carlomagno F, Druck T, Barletta C, Crose CM, Huebner K, Kraus MH and Di Fiore PP (1994) Evolutionary conservation of the EPS8 gene and its mapping to human chromosome 12q23-q24. Oncogene 9: 3057-3061
47. Xiao GH, Jin F, Klein-Szanto AJ, Goodrow TL, Linehan MW and Yeung RS (1997) The FHIT gene product is highly expressed in the cytoplasm of renal tumular epithelium and down-regulated in kidney cancers. Am J Pathol 151: 1541-1547
48. Zerbini C, Gelber RD, Weinberg D, Sallan SE, Barnes P, Kupsky W, Scott RM and Tarbell NJ (1993) Prognostic factors in medulloblastoma including DNA ploidy. J Clin Oncol 11: 616-622