Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats

Pharmacological Research

Volumn 57, Issue 3, 2008, Pages 223-233

  Siniscalco, Dario ^a   Giordano, Catia ^a   Fuccio, Carlo ^a   Luongo, Livio ^a   Ferraraccio, Franca ^a   Rossi, Francesca ^a   de Novellis, Vito ^a   Roth, Kevin A ^b   Maione, Sabatino ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b University of Alabama at Birmingham   (United States)

Author keywords

Apoptosis; Caspase 7; Metabotropic glutamate receptor; Neuropathic pain

Indexed keywords

(3,4 DIHYDRO 2H PYRANO[2,3 B]QUINOLIN 7 YL) (4 METHOXYCYCLOHEXYL)METHANONE; 1 AMINO 1,5 INDANDICARBOXYLIC ACID; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 7; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; JNJ 16259685; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR ANTAGONIST; NESTIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTROCYTOSIS; CONTROLLED STUDY; DRUG EFFICACY; GENE EXPRESSION; GLIOSIS; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MALE; MARKER GENE; MICROSCOPY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NEUROPATHY; SPINAL CORD DORSAL HORN;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BEHAVIOR, ANIMAL; CASPASE 7; CONSTRICTION, PATHOLOGIC; DNA, NEOPLASM; EXCITATORY AMINO ACID ANTAGONISTS; GLIOSIS; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INDANS; MALE; PAIN; PAIN MEASUREMENT; POSTERIOR HORN CELLS; QUINOLINES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SCIATIC NEUROPATHY; SPINAL CORD;

EID: 41549085936     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2008.01.007     Document Type: Article

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