Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons

Neuropharmacology

Volumn 36, Issue 8, 1997, Pages 1047-1055

  Ugolini, A ^a   Corsi, M ^a   Bordi, F ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

1S,3R ACPD; 4CPG; Chelerytrine chloride; DHPG; Ionotropic glutamate receptor agonists; MCPG; Metabotropic glutamate receptor agonists; Nociception; Plasticity; Protein kinase C

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 (CARBOXYCYCLOPROPYL)GLYCINE; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 3,5 DIHYDROXYPHENYLGLYCINE; 4 CARBOXYPHENYLGLYCINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; CHELERYTHRINE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; IONOTROPIC RECEPTOR; KAINIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RECEPTOR SUBTYPE; STAUROSPORINE; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG ANTAGONISM; DRUG POTENTIATION; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL PLASTICITY; NEWBORN; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD HEMISECTION; SPINAL CORD MOTONEURON; VENTRAL ROOT;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CYCLOLEUCINE; DRUG SYNERGISM; EXCITATORY AMINO ACID AGONISTS; GLYCINE; MALE; MEMBRANE POTENTIALS; MOTOR NEURONS; N-METHYLASPARTATE; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RESORCINOLS; SPINAL CORD;

EID: 0030745304     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00103-2     Document Type: Article

References (34)

1. Aiba A., Chen C., Herrup K., Rosenmund C., Stevens C. F. and Tonegawa S. (1994) Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice. Cell 79: 365-375.
2. Anikszejn L., Otani S. and Ben-Ari Y. (1992) Quisqualate metabotropic receptors modulate NMDA currents and facilitate induction of long-term potentiation through protein kinase C. European Journal of Neuroscience 4: 500-504.
3. Birse E. F., Eaton S. A., Jane D. E., Jones P. L., Porter R. H., Pook P. C., Sunter D. C., Udvarhelyi P. M., Wharton B., Roberts P. J., Salt T. E. and Watkins J. C. (1993) Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience 52: 481-488.
4. Bleakman D., Rusin K. I., Chard P. S., Glaum S. R. and Miller R. J. (1992) Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn. Molecular Pharmacology 42: 192-196.
5. Bliss T. V. P. and Collingridge G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39.
6. Bortolotto Z. A., Bashir Z. I., Davies C. H. and Collingridge G. L. (1994) A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation. Nature 368: 740-743.
7. Cerne R. and Randic M. (1992) Modulation of AMPA and NMDA responses in rat spinal dorsal horn neurons by trans-1-aminocyclopentane-1,3-dicarboxylic acid. Neuroscience Letters 144: 180-184.
8. Collingridge G. L., Kehl S. J. and McLennan H. (1983) Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. Journal of Physiology 334: 33-46.
9. Conquet F., Bashir Z. I., Davies C. H., Daniel H., Ferraguti F., Bordi F., Franz-Bacon K., Reggiani A., Matarese V., Condé F., Collingridge G. L. and Crépel F. (1983) Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature 372: 237-243.
10. Corsi M., Quartaroli M., Maraia G., Chiamulera C., Ugolini A., Conquet F., Ratti E. and Ferraguti F. (1996) PLC-coupled-mGLURs and their possible role in pain. Neuropharmacology 35: A9.
11. Fitzjohn S. M., Irving A. J., Palmer M. J., Harvey J., Lodge D. and Collingridge G. L. (1996) Activation of group I mGLURs potentiates NMDA responses in rat hippocampal slices. Neuroscience Letters 203: 211-213.
12. Harvey J. and Collingridge G. L. (1993) Signal transduction patways involved in the acute potentatiation of NMDA responses by 1S,3R-ACPD in rat hippocampal slices. British Journal of Pharmacology 109: 1085-1090.
13. Hayashi Y., Sekiyama N., Nakanishi S., Jane D. E., Sunter D. C., Birse E. F., Udvarhelyi P. M. and Watkins J. C. (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. Journal of Neuroscience 14: 3370-3377.
14. Jane D. E., Jones P. L. S. J., Pook P. C.-K., Tse H.-W. and Watkins J. C. (1993) Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord. British Journal of Pharmacology 112: 809-816.
15. Jones M. W. and Headley P. M. (1995) Interaction between metabotropic and ionotropic glutamate receptor agonist in the rat spinal cord in vivo. Neuropharmacology 34: 1025-1031.
16. Kelso S. R., Nelson T. E. and Leonard J. P. (1992) Protein kinase C-mediated enhancement of NMDA currents by metabotropic glutamate receptors in Xenopus oocytes. Journal of Physiology (London) 449: 705-718.
17. Kinney G. A. and Slater N. T. (1993) Potentiation of NMDA receptor-mediated transmission in turtle cerebbelar granule cells by activation of metabotropic glutamate receptors. Journal of Neurophysiology 69: 585-594.
18. Ko F.-N., Chen I.-S., Wu S.-J., Lee L.-G., Haung T.-F. and Teng C. M. (1990) Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans. Biochimica and Biophysica Acta 1052: 360-365.
19. Malenka R. C. and Nicoll R. A. (1993) NMDA receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends in Neuroscience 16: 521-526.
20. Mannaioni G., Carla V. and Moroni F. (1996) Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations. British Journal of Pharmacology 118: 1530-1536.
21. McGuiness N., Anwyl R. and Rowan M. (1991) Trans-ACPD enhances long-term potentiation in the hippocampus. European Journal of Pharmacology 197: 231-232.
22. Meller S. T., Dykstra C. L. and Gebhart G. F. (1993) Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors. NeuroReport 4: 879-882.
23. Nakanishi S. and Masu M. (1994) Molecular diversity and functions of glutamate receptors. Annual Reviews in Biophysical and Biomolecular Structure 23: 319-348.
24. Pin J.-P. and Duvoisin R. (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34: 1-26.
25. Pook P. C.-K., Sunter D. C., Udvarhelyi P. M. and Watkins J. C. (1992) Evidence for presynaptic depression of monosynaptic excitation in neonatal rat motoneurones by (1S,3S)- and (15,3R)-ACPD. Experimental Physiology 77: 529-532.
26. Rahman S. and Neuman R. S. (1996) Characterization of metabotropic glutamate receptor-mediated facilitation of N-methyl-D-aspartate depolarization of neocortical neurones. British Journal of Pharmacology 117: 675-683.
27. Roche K. W., Tingley W. G. and Huganir R. L. (1994) Glutamate receptor phosphorylation and synaptic plasticity. Current Opinion on Neurobiology 4: 383-388.
28. Shigemoto R., Nakanishi S. and Mizuno N. (1992) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. Journal of Comparative Neurology 322: 121-135.
29. ++ dependent protein kinase. Biochemical and Biophysical Research Communications 135: 397-420.
30. Ugolini A. and Bordi F. (1995) Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus. European Journal of Pharmacology 294: 403-410.
31. Vidnyánszky Z., Hámori J., Négyessy L., Rüegg D., Knöpfel T., Kuhn R. and Görcs T. J. (1994) Cellular and subcellular localization of the mGluR5a metabotropic glutamate receptor in rat spinal cord. NeuroReport 6: 209-213.
32. Wang X. F. and Daw N. W. (1996) Metabotropic glutamate receptors potentiate responses to NMDA and AMPA from layer V cells in rat visual cortex. Journal of Neurophysiology 76: 808-815.
33. Watkins J. and Collingridge G. (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends in Pharmacological Sciences 15: 333-342.
34. Young M. R., Fleetwood-Walker S. M., Mitchell R. and Munro F. E. (1994) The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons. Neuropharmacology 33: 141-144