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Volumn 28, Issue 5, 1997, Pages 633-638

The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord

Author keywords

c fos; GABA; glutamate; LTP (long term potentiation); NMDA; Nociception; spinal cord

Indexed keywords

EXCITATORY AMINO ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 0030974434     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(96)00359-X     Document Type: Review
Times cited : (369)

References (62)
  • 1
    • 0025696555 scopus 로고
    • The non-NMDA receptors: Types, protein structure and molecular biology
    • Barnard E. and Henley J. M. (1990) The non-NMDA receptors: Types, protein structure and molecular biology. Trends Pharm. Sci. 11, 500-507.
    • (1990) Trends Pharm. Sci. , vol.11 , pp. 500-507
    • Barnard, E.1    Henley, J.M.2
  • 2
    • 0026875034 scopus 로고
    • Synaptic plasticity: Long term potentiation in the hippocampus
    • Bashir Z. I. and Collingridge G. L. (1992) Synaptic plasticity: Long term potentiation in the hippocampus. Curr. Opin. Neurobiol. 2, 328-335.
    • (1992) Curr. Opin. Neurobiol. , vol.2 , pp. 328-335
    • Bashir, Z.I.1    Collingridge, G.L.2
  • 3
    • 0024209819 scopus 로고
    • Coexistence of glutamate and substance P in dorsal root ganglion cells of the rat and monkey
    • Battaglia G. and Rustioni A. (1988) Coexistence of glutamate and substance P in dorsal root ganglion cells of the rat and monkey. J. Comp. Neurol. 277, 302-312.
    • (1988) J. Comp. Neurol. , vol.277 , pp. 302-312
    • Battaglia, G.1    Rustioni, A.2
  • 5
    • 0028942137 scopus 로고
    • Synaptic interactions between primary afferent terminals and GABA and nitric oxide-synthesizing neurons in superficial laminae of the rat spinal cord
    • Bernardi P, S., Valtschanoff J. G., Weinberg R. J., Schmidt H. H. H. W. and Rustioni A. (1995) Synaptic interactions between primary afferent terminals and GABA and nitric oxide-synthesizing neurons in superficial laminae of the rat spinal cord. J. Neurosci. 15, 1363-1371.
    • (1995) J. Neurosci. , vol.15 , pp. 1363-1371
    • Bernardi, P.S.1    Valtschanoff, J.G.2    Weinberg, R.J.3    Schmidt, H.H.H.W.4    Rustioni, A.5
  • 6
    • 0023093009 scopus 로고
    • Peripheral and spinal mechanisms of nociception
    • Besson J, M. and Chaouch A. (1987) Peripheral and spinal mechanisms of nociception. Physiol. Rev. 67, 67-186.
    • (1987) Physiol. Rev. , vol.67 , pp. 67-186
    • Besson, J.M.1    Chaouch, A.2
  • 7
    • 0029659012 scopus 로고    scopus 로고
    • B receptor mediated events to inflammatory pain processing: Carrageenan oedema and associated spinal c-Fos expression
    • B receptor mediated events to inflammatory pain processing: Carrageenan oedema and associated spinal c-Fos expression, Neuroscience. 73, 487-496.
    • (1996) Neuroscience , vol.73 , pp. 487-496
    • Buritova, J.1    Chapman, V.2    Honor, P.3    Besson, J.-M.4
  • 8
    • 0027242053 scopus 로고
    • GABA decreases in the spinal cord dorsal horn after peripheral neurectomy
    • Castro-Lopes J. M., Tavares I. and Coimbra A. (1993) GABA decreases in the spinal cord dorsal horn after peripheral neurectomy. Brain Res. 620, 287-291.
    • (1993) Brain Res. , vol.620 , pp. 287-291
    • Castro-Lopes, J.M.1    Tavares, I.2    Coimbra, A.3
  • 9
    • 0028036175 scopus 로고
    • Carrageenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment
    • Castro-Lopes J. M., Tavares I., Tolle T. R. and Coimbra A. (1994) Carrageenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment. Pain 56, 193-201.
    • (1994) Pain , vol.56 , pp. 193-201
    • Castro-Lopes, J.M.1    Tavares, I.2    Tolle, T.R.3    Coimbra, A.4
  • 10
    • 0026527237 scopus 로고
    • The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn
    • Chapman V. and Dickenson A. H. (1992) The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn. Brain Res. 573, 321-323.
    • (1992) Brain Res. , vol.573 , pp. 321-323
    • Chapman, V.1    Dickenson, A.H.2
  • 11
    • 0029080690 scopus 로고
    • The contribution of NMDA receptor activation to spinal c-Fos expression in a model of inflammatory pain
    • Chapman V., Honoré P., Buritova J. and Besson J. M. (1995) The contribution of NMDA receptor activation to spinal c-Fos expression in a model of inflammatory pain. Br. J. Pharmac. 116, 1628-1634.
    • (1995) Br. J. Pharmac. , vol.116 , pp. 1628-1634
    • Chapman, V.1    Honoré, P.2    Buritova, J.3    Besson, J.M.4
  • 12
    • 0026640290 scopus 로고
    • The contribution of excitatory amino-acids to central sensitization and persistent nociception after formalin-induced tissue injury
    • Coderre T. J. and Melzack R. (1992) The contribution of excitatory amino-acids to central sensitization and persistent nociception after formalin-induced tissue injury. J. Neurosci 12, 3665-3670.
    • (1992) J. Neurosci , vol.12 , pp. 3665-3670
    • Coderre, T.J.1    Melzack, R.2
  • 13
    • 0026570984 scopus 로고
    • Benzodiazepines and pain: Effects of midazolam on the activities of nociceptive non-specific dorsal horn neurons in the rat spinal cord
    • Clavier N., Lombard M.-C. and Besson J.-M. (1992) Benzodiazepines and pain: Effects of midazolam on the activities of nociceptive non-specific dorsal horn neurons in the rat spinal cord. Pain 48, 61-71.
    • (1992) Pain , vol.48 , pp. 61-71
    • Clavier, N.1    Lombard, M.-C.2    Besson, J.-M.3
  • 15
    • 0001244862 scopus 로고
    • NMDA receptor antagonists as analgesics
    • Edited by Fields H. L. and Liebeskind J. C., IASP Press, Seattle, WA
    • Dickenson A. H. (1994a) NMDA receptor antagonists as analgesics (Edited by Fields H. L. and Liebeskind J. C.), pp. 173-187. Progress in Pain Research and Management. IASP Press, Seattle, WA.
    • (1994) Progress in Pain Research and Management , pp. 173-187
    • Dickenson, A.H.1
  • 17
    • 0026008423 scopus 로고
    • Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat
    • Dickenson A. H. and Aydar E. (1991) Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat. Neurosci. Lett. 121, 263-266.
    • (1991) Neurosci. Lett. , vol.121 , pp. 263-266
    • Dickenson, A.H.1    Aydar, E.2
  • 18
    • 0022000832 scopus 로고
    • Effects of topical baclofen on C fibre-evoked neuronal activity in the rat dorsal horn
    • Dickenson A. H., Brewer C. M. and Hayes N. A. (1985) Effects of topical baclofen on C fibre-evoked neuronal activity in the rat dorsal horn. Neuroscience 14, 557-562.
    • (1985) Neuroscience , vol.14 , pp. 557-562
    • Dickenson, A.H.1    Brewer, C.M.2    Hayes, N.A.3
  • 19
    • 0023501963 scopus 로고
    • Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones
    • Dickenson A. H. and Sullivan A. F. (1987) Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones. Neurosci. Lett. 83, 207-211.
    • (1987) Neurosci. Lett. , vol.83 , pp. 207-211
    • Dickenson, A.H.1    Sullivan, A.F.2
  • 20
    • 0028802694 scopus 로고
    • Intrathecal baclofen and muscimol, but not midazolam, are antinociceptive using the rat-formalin model
    • Dirig D. M. and Yaksh T. L. (1995) Intrathecal baclofen and muscimol, but not midazolam, are antinociceptive using the rat-formalin model. J. Pharmac. Exp. Ther. 275, 219-227.
    • (1995) J. Pharmac. Exp. Ther. , vol.275 , pp. 219-227
    • Dirig, D.M.1    Yaksh, T.L.2
  • 21
    • 0028038355 scopus 로고
    • Relief of post-herpetic neuralgia with the N-methyl-D-aspartate receptor antagonist ketamine: A double blind, cross-over comparison with morphine and placebo
    • Eide P. K., Jorum E., Stubhaug A., Bremnez J. and Breivik H. (1994) Relief of post-herpetic neuralgia with the N-methyl-D-aspartate receptor antagonist ketamine: A double blind, cross-over comparison with morphine and placebo. Pain 58, 347-354.
    • (1994) Pain , vol.58 , pp. 347-354
    • Eide, P.K.1    Jorum, E.2    Stubhaug, A.3    Bremnez, J.4    Breivik, H.5
  • 22
    • 0028210650 scopus 로고
    • The effects of the clinically tested NMDA receptor antagonist memantine on carrageenin-induced thermal hyperalgesia in rats
    • Eisenberg E., LaCross S. and Strassman A. M. (1994) The effects of the clinically tested NMDA receptor antagonist memantine on carrageenin-induced thermal hyperalgesia in rats. Eur. J. Pharmac. 255, 123-129.
    • (1994) Eur. J. Pharmac. , vol.255 , pp. 123-129
    • Eisenberg, E.1    LaCross, S.2    Strassman, A.M.3
  • 24
    • 0027408318 scopus 로고
    • Painful neuropathy: Altered central processing maintained dynamically by peripheral input
    • Gracely R., Lynch S. A., Bennet G. J. (1993) Painful neuropathy: Altered central processing maintained dynamically by peripheral input. Pain 52, 251-253.
    • (1993) Pain , vol.52 , pp. 251-253
    • Gracely, R.1    Lynch, S.A.2    Bennet, G.J.3
  • 25
    • 0025307284 scopus 로고
    • Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat
    • Haley J. E., Sullivan A. F. and Dickenson A. H. (1990) Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat. Brain Res. 518, 218-226.
    • (1990) Brain Res. , vol.518 , pp. 218-226
    • Haley, J.E.1    Sullivan, A.F.2    Dickenson, A.H.3
  • 26
    • 0020382552 scopus 로고
    • Pharmacological studies on the prolonged depressant effects of baclofen on lumber dorsal horn units in the cat
    • Henry J. L. (1982) Pharmacological studies on the prolonged depressant effects of baclofen on lumber dorsal horn units in the cat. Neuropharmacology 21, 1085-1093.
    • (1982) Neuropharmacology , vol.21 , pp. 1085-1093
    • Henry, J.L.1
  • 27
    • 0028306527 scopus 로고
    • Role of excitatory amino acid receptors in the mediation of the nociceptive response to formalin in the rat
    • Hunter J. C. and Singh L. (1994) Role of excitatory amino acid receptors in the mediation of the nociceptive response to formalin in the rat. Neurosci. Lett. 174, 217-221.
    • (1994) Neurosci. Lett. , vol.174 , pp. 217-221
    • Hunter, J.C.1    Singh, L.2
  • 28
    • 0018824936 scopus 로고
    • Baclofen; stereoselective inhibition of excitatory amino acid release
    • Johnston G. A. R., Hailstone M. H. and Freeman C. G. (1980) Baclofen; stereoselective inhibition of excitatory amino acid release. J. Pharm. Pharmac. 32, 230-231.
    • (1980) J. Pharm. Pharmac. , vol.32 , pp. 230-231
    • Johnston, G.A.R.1    Hailstone, M.H.2    Freeman, C.G.3
  • 29
    • 0007402545 scopus 로고
    • Endogenous opioid systems in the modulation of pain: Behavioural studies in rat models of persistent hyperalgesia
    • Edited by Gebhart G. F., Hammond D. L. and Jensen T., IASP Press, Seattle, WA
    • Kayser V. (1994) Endogenous opioid systems in the modulation of pain: Behavioural studies in rat models of persistent hyperalgesia In Proceedings of the 7th World Congress on Pain, Progress in Pain Research and Management (Vol. 2) (Edited by Gebhart G. F., Hammond D. L. and Jensen T.), pp. 553-568. IASP Press, Seattle, WA.
    • (1994) Proceedings of the 7th World Congress on Pain, Progress in Pain Research and Management , vol.2 , pp. 553-568
    • Kayser, V.1
  • 30
    • 0001271781 scopus 로고
    • The NMDA antagonist MK801 reduces noxious stimulus-evoked FOS expression in the spinal cord dorsal horn
    • Edited by Bond, Charlton and Woolf, Elsevier, Amsterdam
    • Kehl L. J., Gogas K. R., Lichtblau L., Pollack C. H., Mayes M., Basbaum A. I. and Wilcox G. L. (1991) The NMDA antagonist MK801 reduces noxious stimulus-evoked FOS expression in the spinal cord dorsal horn In Proceedings of the IVth World Congress on Pain. (Edited by Bond, Charlton and Woolf), p. 307. Elsevier, Amsterdam.
    • (1991) Proceedings of the IVth World Congress on Pain , pp. 307
    • Kehl, L.J.1    Gogas, K.R.2    Lichtblau, L.3    Pollack, C.H.4    Mayes, M.5    Basbaum, A.I.6    Wilcox, G.L.7
  • 31
    • 0028327701 scopus 로고
    • Simultaneous LTP of non-NMDA- and LTD of NMDA-receptor-mediated responses in the nucleus accumbens
    • Kombain S. B. and Malenka R. C. (1994) Simultaneous LTP of non-NMDA- and LTD of NMDA-receptor-mediated responses in the nucleus accumbens. Nature 368, 242-246.
    • (1994) Nature , vol.368 , pp. 242-246
    • Kombain, S.B.1    Malenka, R.C.2
  • 32
    • 0028148852 scopus 로고
    • Spinal cord SP release and hyperalgesia in monoarthritic rats; involvement of the GABA B receptor system
    • Malcangio M. and Bowery N. (1994) Spinal cord SP release and hyperalgesia in monoarthritic rats; involvement of the GABA B receptor system. Br. J. Pharmac. 113, 1561-1566.
    • (1994) Br. J. Pharmac. , vol.113 , pp. 1561-1566
    • Malcangio, M.1    Bowery, N.2
  • 33
    • 0027942571 scopus 로고
    • Release of adenosine by activation of NMDA receptors in the hippocampus
    • Manzoni O. J., Manabe T. and Nicoll R. A. (1994) Release of adenosine by activation of NMDA receptors in the hippocampus. Science 265, 2098-2101.
    • (1994) Science , vol.265 , pp. 2098-2101
    • Manzoni, O.J.1    Manabe, T.2    Nicoll, R.A.3
  • 34
    • 0027466924 scopus 로고
    • Intrathecal treatment with dextrophan or ketamine potently reduces pain related behaviours in a rat model of peripheral mononeuropathy
    • Mao J., Price D. D., Hayes R. L., Lu J., Mayer D. J. and Frenk H. (1993) Intrathecal treatment with dextrophan or ketamine potently reduces pain related behaviours in a rat model of peripheral mononeuropathy. Brain Res. 605, 164-168.
    • (1993) Brain Res. , vol.605 , pp. 164-168
    • Mao, J.1    Price, D.D.2    Hayes, R.L.3    Lu, J.4    Mayer, D.J.5    Frenk, H.6
  • 35
    • 0023492484 scopus 로고
    • Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones
    • Mayer M. L. and Westbrook G. L. (1987) Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. J. Physiol. (Lond) 394, 501-527.
    • (1987) J. Physiol. (Lond) , vol.394 , pp. 501-527
    • Mayer, M.L.1    Westbrook, G.L.2
  • 36
    • 0028133361 scopus 로고
    • Chemically-diverse ligands at the glycine B site coupled to N-methyl-D-aspartate (NMDA) receptors selectively block the late phase of formalin-induced pain in mice
    • Millan M. J. and Segiun L. (1994) Chemically-diverse ligands at the glycine B site coupled to N-methyl-D-aspartate (NMDA) receptors selectively block the late phase of formalin-induced pain in mice. Neurosci. Lett. 178, 139-143.
    • (1994) Neurosci. Lett. , vol.178 , pp. 139-143
    • Millan, M.J.1    Segiun, L.2
  • 38
    • 0027988694 scopus 로고
    • The N-methyl-D-aspartate antagonist dextromethorphan selectively reduces temporal summation of second pain
    • Price D. D., Mao J., Frenk H. and Mayer D. J. (1994) The N-methyl-D-aspartate antagonist dextromethorphan selectively reduces temporal summation of second pain. Pain 59, 165-174.
    • (1994) Pain , vol.59 , pp. 165-174
    • Price, D.D.1    Mao, J.2    Frenk, H.3    Mayer, D.J.4
  • 39
    • 0028883696 scopus 로고
    • The roles of adenosine in the control of acute and more persistent nociceptive responses of dorsal horn neurones in the anaesthetized rat
    • Reeve A. J. and Dickenson A. H. (1995) The roles of adenosine in the control of acute and more persistent nociceptive responses of dorsal horn neurones in the anaesthetized rat. Br. J. Pharm. 116, 2221-2228.
    • (1995) Br. J. Pharm. , vol.116 , pp. 2221-2228
    • Reeve, A.J.1    Dickenson, A.H.2
  • 40
    • 0026669928 scopus 로고
    • The intrathecal administration of excitatory amino-acid antagonists selectively attenuates carrageenan-induced behavioral hyperalgesia in rats
    • Ren K., Williams G. M., Hylden L. K., Ruda M. A. and Dubner R. (1992) The intrathecal administration of excitatory amino-acid antagonists selectively attenuates carrageenan-induced behavioral hyperalgesia in rats. Eur. J. Pharmac. 219, 235-243.
    • (1992) Eur. J. Pharmac. , vol.219 , pp. 235-243
    • Ren, K.1    Williams, G.M.2    Hylden, L.K.3    Ruda, M.A.4    Dubner, R.5
  • 41
    • 0027414445 scopus 로고
    • Evidence that neuropeptide Y is present in GABAergic neurons in the superficial dorsal horn of the rat spinal cord
    • Rowan S., Todd A. J. and Spike R. C. (1993) Evidence that neuropeptide Y is present in GABAergic neurons in the superficial dorsal horn of the rat spinal cord. Neuroscience 53, 537-545.
    • (1993) Neuroscience , vol.53 , pp. 537-545
    • Rowan, S.1    Todd, A.J.2    Spike, R.C.3
  • 42
    • 0023137280 scopus 로고
    • GABAergic mechanisms of analgesia; an update
    • Sawynok J. (1987) GABAergic mechanisms of analgesia; an update. Pharmac. Biochem. Behav. 26, 463-474.
    • (1987) Pharmac. Biochem. Behav. , vol.26 , pp. 463-474
    • Sawynok, J.1
  • 43
    • 0025824690 scopus 로고
    • The effects of NMDA antagonists on neuronal activity in cat spinal cord evoked by acute inflammation in the knee joint
    • Schaible H. G., Grubb B. D., Neugebauer V. and Oppmann M. (1991) The effects of NMDA antagonists on neuronal activity in cat spinal cord evoked by acute inflammation in the knee joint. Eur. J. Neurosci. 3, 981-991.
    • (1991) Eur. J. Neurosci. , vol.3 , pp. 981-991
    • Schaible, H.G.1    Grubb, B.D.2    Neugebauer, V.3    Oppmann, M.4
  • 44
    • 0025889989 scopus 로고
    • Modulation of neuropathic pain in rats by spinal disinhibition and NMDA receptor blockade of injury discharge
    • Seltzer Z., Cohn S., Ginzburg R. and Beilin B. (1991) Modulation of neuropathic pain in rats by spinal disinhibition and NMDA receptor blockade of injury discharge. Pain 45, 69-75.
    • (1991) Pain , vol.45 , pp. 69-75
    • Seltzer, Z.1    Cohn, S.2    Ginzburg, R.3    Beilin, B.4
  • 45
    • 0025310703 scopus 로고
    • N-Methyl-D-aspartate receptors mediate responses of rat dorsal horn neurones to hindlimb ischaemia
    • Sher G. and Mitchell D. (1990) N-Methyl-D-aspartate receptors mediate responses of rat dorsal horn neurones to hindlimb ischaemia. Brain Res. 522, 55-62.
    • (1990) Brain Res. , vol.522 , pp. 55-62
    • Sher, G.1    Mitchell, D.2
  • 46
    • 0026615116 scopus 로고
    • - channels modulated by multiple drug-binding sites
    • - channels modulated by multiple drug-binding sites. Trends Pharm. Sci. 13, 446-451.
    • (1992) Trends Pharm. Sci. , vol.13 , pp. 446-451
    • Sieghart, W.1
  • 47
    • 0028968635 scopus 로고
    • Galanin is contained in GABAergic neurons in the rat spinal dorsal horn
    • Simmons D. R., Spike R. C. and Todd A. J. (1995) Galanin is contained in GABAergic neurons in the rat spinal dorsal horn. Neurosci. Lett. 187, 119-122.
    • (1995) Neurosci. Lett. , vol.187 , pp. 119-122
    • Simmons, D.R.1    Spike, R.C.2    Todd, A.J.3
  • 48
    • 0028168576 scopus 로고
    • A and glycine receptors to central sensitization: Disinhibition and touch-evoked allodynia in the spinal cord
    • A and glycine receptors to central sensitization: Disinhibition and touch-evoked allodynia in the spinal cord. J. Neurophysiol. 72, 169-179.
    • (1994) J. Neurophysiol. , vol.72 , pp. 169-179
    • Sivilotti, L.1    Woolf, C.2
  • 50
    • 0026761106 scopus 로고
    • Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan induced inflammation
    • Stanfa L. C., Sullivan A. F. and Dickenson A. H. (1992) Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan induced inflammation. Pain 50, 345-354.
    • (1992) Pain , vol.50 , pp. 345-354
    • Stanfa, L.C.1    Sullivan, A.F.2    Dickenson, A.H.3
  • 51
    • 0028848216 scopus 로고
    • Persistent cardiovascular and behavioral responses to subcutaneous formalin require peripheral nerve input
    • Taylor B. K., Peterson M. A. and Basbaum A. I. (1995) Persistent cardiovascular and behavioral responses to subcutaneous formalin require peripheral nerve input. J. Neurosci. 15, 7575-7584.
    • (1995) J. Neurosci. , vol.15 , pp. 7575-7584
    • Taylor, B.K.1    Peterson, M.A.2    Basbaum, A.I.3
  • 52
    • 0024835205 scopus 로고
    • GABA-immunoreactive neurons in the dorsal horn of the rat spinal cord
    • Todd A. J. and McKenzie J. (1989) GABA-immunoreactive neurons in the dorsal horn of the rat spinal cord. Neuroscience 31, 799-806.
    • (1989) Neuroscience , vol.31 , pp. 799-806
    • Todd, A.J.1    McKenzie, J.2
  • 53
    • 0026752966 scopus 로고
    • Immunohistochemical evidence that Met-enkephalin and GABA coexist in some neurones in rat dorsal horn
    • Todd A. J. and Spike R. C. (1992) Immunohistochemical evidence that Met-enkephalin and GABA coexist in some neurones in rat dorsal horn. Brain Res. 584, 149-156.
    • (1992) Brain Res. , vol.584 , pp. 149-156
    • Todd, A.J.1    Spike, R.C.2
  • 54
    • 0029927346 scopus 로고    scopus 로고
    • Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord
    • Todd A. J., Watt C., Spike R. C. and Sieghart W. (1996) Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord. J. Neurosci. 16, 974-982.
    • (1996) J. Neurosci. , vol.16 , pp. 974-982
    • Todd, A.J.1    Watt, C.2    Spike, R.C.3    Sieghart, W.4
  • 55
    • 0000411529 scopus 로고
    • c-Fos induction in the spinal cord following noxious stimulation: Prevention by opiates but not by NMDA antagonists
    • Edited by Bond, Charlton and Woolf, Elsevier, Amsterdam
    • Tölle T. R., Castro-Lopes J. M., Evan G. and Zieglgänsberger W. (1991) c-Fos induction in the spinal cord following noxious stimulation: Prevention by opiates but not by NMDA antagonists In Proceedings of the IVth World Congress on Pain. (Edited by Bond, Charlton and Woolf), p. 299. Elsevier, Amsterdam.
    • (1991) Proceedings of the IVth World Congress on Pain , pp. 299
    • Tölle, T.R.1    Castro-Lopes, J.M.2    Evan, G.3    Zieglgänsberger, W.4
  • 56
    • 0027196757 scopus 로고
    • NMDA receptor antagonists, MK-801 and ACEA-1011, prevent the development of tonic pain following subcutaneous formalin
    • Vaccarino A. L., Marek P., Kest B., Weber E., Keana J. F. and Liebeskind J. C. (1993) NMDA receptor antagonists, MK-801 and ACEA-1011, prevent the development of tonic pain following subcutaneous formalin. Brain Res. 615, 331-334.
    • (1993) Brain Res. , vol.615 , pp. 331-334
    • Vaccarino, A.L.1    Marek, P.2    Kest, B.3    Weber, E.4    Keana, J.F.5    Liebeskind, J.C.6
  • 57
    • 0027992583 scopus 로고
    • Phenylglycine derivative as antagonists of metatotropic glutamate receptors
    • Watkins J. and Collingridge G. (1994) Phenylglycine derivative as antagonists of metatotropic glutamate receptors. Trends Pharm. Sci. 15, 333-342.
    • (1994) Trends Pharm. Sci. , vol.15 , pp. 333-342
    • Watkins, J.1    Collingridge, G.2
  • 58
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury hypersensitivity states
    • Woolf C. J. and Thompson S. W. N. (1991) The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury hypersensitivity states. Pain 44, 293-299.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.N.2
  • 59
    • 0024602581 scopus 로고
    • Behavioural and autonomie correlates of the tactile evoked allodynia produced by spinal glycine inhibition: Effects of modulatory receptor systems and excitatory amino acid antagonists
    • Yaksh T. L. (1989) Behavioural and autonomie correlates of the tactile evoked allodynia produced by spinal glycine inhibition: Effects of modulatory receptor systems and excitatory amino acid antagonists. Pain 37, 111-123.
    • (1989) Pain , vol.37 , pp. 111-123
    • Yaksh, T.L.1
  • 60
    • 0026629818 scopus 로고
    • Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat
    • Yamamoto T. and Yaksh T. L. (1992a) Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat. Anesthesiology 77, 757-763.
    • (1992) Anesthesiology , vol.77 , pp. 757-763
    • Yamamoto, T.1    Yaksh, T.L.2
  • 61
    • 0026545821 scopus 로고
    • Studies on the spinal interaction of morphine and the NMDA antagonist MK-801 on the hyperesthesia observed in a rat model of sciatic mononeuropathy
    • Yamamoto T. and Yaksh T. L. (1992b) Studies on the spinal interaction of morphine and the NMDA antagonist MK-801 on the hyperesthesia observed in a rat model of sciatic mononeuropathy. Neurosci. Lett. 135, 67-70.
    • (1992) Neurosci. Lett. , vol.135 , pp. 67-70
    • Yamamoto, T.1    Yaksh, T.L.2
  • 62
    • 0027300596 scopus 로고
    • Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801
    • Yamamoto T. and Yaksh T. L. (1993) Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801. Pain 54, 79-84.
    • (1993) Pain , vol.54 , pp. 79-84
    • Yamamoto, T.1    Yaksh, T.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.