Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation

GLIA

Volumn 47, Issue 2, 2004, Pages 180-188

  Uhlmann, Erik J ^a   Li, Wen ^a   Scheidenhelm, Danielle K ^a   Gau, Chia Ling ^b   Tamanoi, Fuyuhiko ^b   Gutmann, David H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Glia; GTPase; Hamartin; mTOR

Indexed keywords

DIMETHYL SULFOXIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; HAMARTIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN KINASE B; PROTEIN TSC1; RAPAMYCIN; S6 KINASE; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; TUBERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL SIZE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUBEROUS SCLEROSIS; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; CELL DIFFERENTIATION; CELL SIZE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CONTACT INHIBITION; DOWN-REGULATION; ENZYME INHIBITORS; MICE; MICE, KNOCKOUT; MONOMERIC GTP-BINDING PROTEINS; NEUROPEPTIDES; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 3943106696     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.20036     Document Type: Article

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