gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

Cell

Volumn 96, Issue 4, 1999, Pages 529-539

  Ito, Naoto ^a   Rubin, Gerald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL PROLIFERATION; DROSOPHILA MELANOGASTER; GENE MUTATION; GENE SEQUENCE; GROWTH REGULATION; HUMAN; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TUBEROUS SCLEROSIS;

DROSOPHILA;

EID: 0033582748     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80657-1     Document Type: Article

References (56)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D.J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Basler, K., and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
3. Braet, F., De Zanger, R., and Wisse, E. (1997). Drying cells for SEM, AFM and TEM by hexamethyldisilazane: a study on hepatic endothelial cells. J. Microsc. 186, 84-87.
4. Canal, I., Fariñas, I., Gho, M., and Ferrús, A. (1994). The presynaptic cell determines the number of synapses in the Drosophila optic ganglia. Eur. J. Neurosci. 6, 1423-1431.
5. Chou, T.B., Noll, E., and Perrimon, N. (1993). Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germ line chimeras. Development 119, 1359-1369.
6. Dahmann, C., Diffley, J.F.X., and Nasmyth, K.A. (1995). S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state. Curr. Biol. 5, 1257-1269.
7. Fain, M.J., and Stevens, B. (1982). Alterations in the cell cycle of Drosophila imaginai disc cells precede metamophosis. Dev. Biol. 92, 247-258.
8. Fen, S., and Ready, D.F. (1997). Glued participates in distinct micro-tubule-based activities in Drosophila eye development. Development 124, 1497-1507.
9. Ferrús, A., and García-Bellido, A. (1976). Morphogenetic mutants detected in mitotic recombination clones. Nature 260, 425-426.
10. Gateff, E. (1994). Tumor suppressor and overgrowth suppressor genes of Drosophila melanogaster. Developmental aspects. Int. J. Dev. Biol. 38, 565-590.
11. Gomez, M.R. (1988). Tuberous Sclerosis, Second Edition (New York: Raven Press).
12. Gomez, M.R. (1991). Phenotypes of the tuberous sclerosis complex with a revision of diagnostic criteria. Ann. N.Y. Acad. Sci. 675, 1-7.
13. Green, A.J., Smith, M., and Yates, J.R.W. (1994). Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients. Nat. Genet. 6, 193-196.
14. Hayashi, S. (1996). A Cdc2 dependent checkpoint maintains diploidy in Drosophila. Development 122, 1051-1058.
15. Hendzel, M.J., Wei, Y., Mancini, M.A., Van Hooser, A., Ranalli, T., Brinkley, B.R., Bazett-Jones, D.P., and Allis, C.D. (1997). Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 106, 348-360.
16. Henske, E.P., Neumann, H.P.H., Scheithauer, B.W., Herbst, E.W., Short, M.P., and Kwiatkowski, D.J. (1995). Loss of heterozygosity in the tuberous sclerosis (TSC2) region of chromosome band 16p13 occurs in sporadic as well as TSC-associated renal angiomyolipomas. Genes Chromosomes Cancer 13, 295-298.
17. Johnson, W.G., Yoshidome, H., Sternroos, E.S., and Davidson, M.M. (1991). Origin of the neuron-like cells in tuberous sclerosis tissues. Ann. N.Y. Acad. Sci. 675, 211-219.
18. Karim, F.D., Chang, H.C., Therrien, M., Wasserman, D.A., Laverty, T., and Rubin, G.M. (1996). A screen for genes that function down-stream of Ras1 during Drosophila eye development. Genetics 143, 315-329.
19. Kimmel, B.E., Heberlein, U., and Rubin, G.M. (1990). The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 4, 712-727.
20. Kimmerly, W., Stultz, K., Lewis, S., Lewis, K., Lustre, V., Romero, R., Benke, J., Sun, D., Shirley, G., Martin, C., and Palazzolo, M. (1996). A P1-based physical map of the Drosophila euchromatic genome. Genome Res. 6, 414-430.
21. Knoblich, J.A., and Lehner, C.F. (1993). Synergistic action of Drosophila cyclins A and B during the G2-M transition. EMBO J. 12, 65-74.
22. Kylsten, P., and Saint, R. (1997). Imaginai tissues of Drosophila melanogaster exhibit different modes of cell proliferation control. Dev. Biol. 192, 509-522.
23. Maheshwar, M.M., Sandford, R., Nellist, M., Cheadle, J.P., Sgotto, B., Vaudin, M., and Sampson, J.R. (1996). Comparative analysis and genomic structure of the tuberous sclerosis 2 (TSC2) gene in human and pufferfish. Hum. Mol. Genet. 5, 131-137.
24. Maki, C., Rhoads, D.D., Stewart, M.J., Van Slyke, B., and Roufa, D.J. (1989). The Drosophila melanogaster RPS17 gene encoding ribosomal protein S17. Gene 79, 289-298.
25. Morgan, D.O. (1997). Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 13, 261-291.
26. Neufeld, T.P., de la Cruz, A.F.A., Johnston, L.A., and Edgar, B.A. (1998a). Coordination of growth and cell division in the Drosophila wing. Cell 93, 1183-1193.
27. Neufeld, T.P., Tang, A.H., and Rubin, G.M. (1998b). A genetic screen to identify components of the sina signaling pathway in Drosophila eye development. Genetics 148, 277-286.
28. Pirrotta, V., Bickel, S., and Mariani, C. (1988). Developmental expression of the Drosophila zeste gene and localization of zeste protein on polytene chromosomes. Genes Dev. 2, 1839-1850.
29. Povey, S., Burley, M.W., Attwood, J., Benham, F., Hunt, D., Jeremiah, S.J., Franklin, D., Gillet, G., Malas, S., Robson, E.B., et al. (1994). Two loci for tuberous sclerosis: one on 9q34 and one on 16p13. Ann. Hum. Genet. 58, 107-127.
30. Ready, D.F., Hanson, T.E., and Benzer, S. (1976). Development of the Drosophila retina, a neurocrystalline lattice. Dev. Biol. 53, 217-240.
31. Robinow, S., and White, K. (1991). Characterization and spatial distribution of the ELAVprotein during Drosophila melanogaster development. J. Neurobiol. 22, 443-461.
32. Sanger, F., Nicklen, S., and Coulson, A. (1977). DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
33. Scheffzek, K., Ahmadian, M.R., and Wittinghofer, A. (1998). GTPase-activating proteins: helping hands to complement an active site. Trends Biochem. Sci. 23, 257-262.
34. Sigrist, S., Jacobs, H., Stratmann, R., and Lehner, C.F. (1995). Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B, and B3. EMBO J. 14, 4827-4838.
35. Simpson, P., and Morata, G. (1981). Differential mitotic rates and patterns of growth in compartments in the Drosophila wing. Dev. Biol. 85, 299-308.
36. Spradling, A.C., Stern, D.M., Kiss, I., Laverty, T., and Rubin, G.M. (1995). Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92, 10824-10830.
37. Stillman, B. (1996). Cell cycle control of DNA replication. Science 274, 1659-1664.
38. Su, T.T., and O'Farrell, P.H. (1998). Size control: cell proliferation does not equal growth. Curr. Biol. 8, R687-R689.
39. Su, T.T., Follette, P.J., and O'Farrell, P.H. (1995). Qualifying for the license to replicate. Cell 81, 825-828.
40. The European Chromosome 16 Tuberous Sclerosis Consortium. (1993). Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell 75, 1305-1315.
41. Thomas, B.J., Gunning, D.A., Cho, J., and Zipursky, S.L. (1994). Cell cycle progression in the developing Drosophila eye: roughex encodes a novel protein required for the establishment of G1. Cell 77, 1003-1014.
42. Thomas, B.J., Zavitz, K.H., Dong, X., Lane, M.E., Weigmann, K., Finley, R.L., Jr., Brent, R., Lehner, C.F., and Zipursky, S.L. (1997). roughex down-regulates G2 cyclins in G1. Genes Dev. 11, 1289-1298.
43. Thompson, J.D., Higgins, D.G., and Gibson, T.J. (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680.
44. Tomlinson, A., and Ready, D.F. (1987a). Cell fate in the Drosophila ommatidium. Dev. Biol. 123, 264-275.
45. Tomlinson, A., and Ready, D.F. (1987b). Neuronal differentiation in the Drosophila ommatidium. Dev. Biol. 120, 366-376.
46. Tsuchiya, H., Orimoto, K., Kobayashi, T., and Hino, O. (1996). Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (TSC2) gene product of the Eker rat model. Cancer Res. 56, 429-433.
47. van Slegtenhorst, M., de Hoogt, R., Hermans, C., Nellist, M., Janssen, B., Verhoef, S., Lindhout, D., van den Ouwerland, A., Halley, D., Young, J., et al. (1997). Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science 277, 805-808.
48. Vincent, J.-P., Girdham, C.H., and O'Farrell, P.M. (1994). A cell-autonomous, ubiquitous marker for the analysis of Drosophila genetic mosaics. Dev. Biol. 764, 328-331.
49. Weigmann, K., Cohen, S.M., and Lehner, C.F. (1997). Cell cycle progression, growth and patterning in imaginai discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. Development 124, 3555-3563.
50. Wienecke, R., König, A., and DeClue, J.E. (1995). Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity. J. Biol. Chem. 270, 16409-16414.
51. Wienecke, R., Maize, J.C., Jr., Shoarinejad, F., Vass, W.C., Reed, J., Bonifacino, J.S., Resau, J.H., de Gunzburg, J., Yeung, R.S., and DeClue, J.E. (1996). Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus. Oncogene 13, 913-923.
52. Wilson, P.J., Ramesh, V., Kristiansen, A., Bove, C., Jozwiak, S., Kwiatkowski, D.J., Short, M.P., and Haines, J.L. (1996). Novel mutations detected in the TSC2 gene from both sporadic and familial TSC patients. Hum. Mol. Genet. 5, 249-256.
53. Winberg, M.L., Perez, S.E., and Steller, H. (1992). Generation and early differentiation of glial cells in the first optic ganglion of Drosophila melanogaster. Development 115, 903-911.
54. Wolff, T., and Ready, D.F. (1993). Pattern formation in the Drosophila retina. In The Development of Drosophila melanogaster, M. Bate and A.M. Arias, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Press), pp. 1277-1325.
55. Xiao, G.-H., Shoarinejad, F., Jin, F., Golemis, E.A., and Yeung, R.S. (1997). The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis. J. Biol. Chem. 272, 6097-6100.
56. Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.