Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Nature Medicine

Volumn 14, Issue 2, 2008, Pages 144-153

  Danial, Nika N ^a   Walensky, Loren D ^a,b   Zhang, Chen Yu ^c   Choi, Cheol Soo ^d   Fisher, Jill K ^a   Molina, Anthony J A ^e   Datta, Sandeep Robert ^b,h   Pitter, Kenneth L ^a,b   Bird, Gregory H ^a,b   Wikstrom, Jakob D ^e   Deeney, Jude T ^f   Robertson, Kirsten ^a   Morash, Joel ^a,b   Kulkarni, Ameya ^d   Neschen, Susanne ^d   Kim, Sheene ^d   Greenberg, Michael E ^b   Corkey, Barbara E ^f   Shirihai, Orian S ^e   Shulman, Gerald I ^d   Lowell, Bradford B ^g   Korsmeyer, Stanley J ^a,d   more..

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c NANJING UNIVERSITY   (China)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f BOSTON MEDICAL CENTER   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

^h Harvard Medical School ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINYLLEUCYLTRYPTOPHYLALANYLALANYLGLUTAMINYLARGINYLTYROSYL GLYCYLARGINYLGLUTAMYLLEUCYLARGINYLARGINYLMETHIONYLSERYLASPARTYLGLUTAMYL PHENYLALANYLGLUTAMYLGLYCYLSERYLPHENYLALANYLLYSINE; ASPARAGINYLLEUCYLTRYPTOPHYLALANYLALANYLGLUTAMINYLARGINYLTYROSYL GLYCYLARGINYLGLUTAMYLLEUCYLARGINYLARGINYLMETHIONYLSERYLASPARTYLGLUTAMYL PHENYLALANYLVALYLASPARTYLSERYLPHENYLALANYLLYSYLLYSINE; BH3 PROTEIN; GLUCOKINASE; HYDROCARBON; INSULIN; PEPTIDE; PROTEIN BAD; UNCLASSIFIED DRUG;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; GENE CONTROL; GENE FUNCTION; GENE SEQUENCE; GENETIC ANALYSIS; INSULIN RELEASE; LIPID DIET; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; BCL-ASSOCIATED DEATH PROTEIN; BLOOD GLUCOSE; CALCIUM; CELL COUNT; CELL SURVIVAL; DIET; GLUCOKINASE; GLUCOSE; HUMANS; HYDROCARBONS; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHOSERINE; PROTEIN STRUCTURE, TERTIARY;

EID: 38949140180     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1717     Document Type: Article

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