Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, interleukin-1β and TNF-α

Mediators of Inflammation

Volumn 9, Issue 3-4, 2000, Pages 155-160

  Sasaki, M ^a   Kashima, M ^a   Ito, T ^a   Watanabe, A ^a   Izumiyama, N ^a   Sano, M ^a   Kagaya, M ^a   Shioya, T ^a   Miura, M ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Human; IL 1 ; Lung fibroblast; Metalloproteinase; PDGF; TNF 1

Indexed keywords

COLLAGENASE; INTERLEUKIN 1BETA; METALLOPROTEINASE; PLATELET DERIVED GROWTH FACTOR; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; ENZYME IMMUNOASSAY; ENZYME REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG FUNCTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS INHIBITION;

EID: 0033669058     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629350020002895     Document Type: Article

References (38)

1. The role of intraalveolar fibrosis in the process of pulmonary structural remodeling in patients with diffuse alveolar damage
2. Production of collagenase and tissue inhibitor of metalloproteinases by fibroblasts derived from normal and fibrotic human lungs
3. Interleukin-1 and transforming growth factor-α: Synergistic stimulation of metalloproteinases, PGE2 and proliferation in human fibroblasts
4. Alteration of chemotactic response of human skin fibroblasts to PDGF by growth factors
5. Platelet-derived growth factor is chemotactic for fibroblasts
6. TNF-α stimulation of fibroblast proliferation
7. Interleukin-1, a potent regulator of fibroblast proliferation
8. Differential regulation of collagen, glycosaminoglycan, fibronectin, collagenase activity production in cultured human adult dermal fibroblasts interleukin 1-alpha and beta and tumor necrosis factor-alpha and beta
9. Quantitative in vitro assay for tumor cell invasion through extracellular matrix or into protein gels
10. Efficient purification of TIMP-2 from culture medium conditioned by human hepatoma cell line, and its inhibitory effects on metalloproteinases and in vitro tumor invasion
11. Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin(pump-1), secreted from human rectal carcinoma cell line
12. Expression of type IV collagenase and procollageneses and its correlation with tumorigenic invasive, and metastatic abilities of oncogene-transformed human bronchial epithelial cells
13. Stromelysin/transin and tumor progression
14. Stromelysin, a connective tissue-degrading metaloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase
15. Control of collagen deposition in mammalian lung
16. Coccentration, biosynthesis and degradation of collagen in idiopathic pulmonary fibrosis
17. Production of fibronectin by human alveolar macrophage: Mechanism for the recruitment of fibroblast to sites of tissue injury in interstitial lung diseases
18. Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis
19. Platelet-derived growth factor in pulmonary fibrosis
20. Presence of platelet-derived growth factor in normal and fibrofic lung is specifically associated with interstitial macrophages, while both interstitial macrophages and alveolar epithelial cells express the c-sis protooncogene
21. Stimulation of human synovial fibroblast DNA synthesis by platelet-derived growth factor and fibroblast growth factor
22. Expression of platelet-derived growth factor-β receptors on human fibroblasts
23. Expression of a 2.8-kb PDGF-/c-sis transcript and synthesis of PDGF-like protein by human lung fibroblasts
24. Tumor necrosis factor-induced expression of platelet-derived growth factor A chain messenger RNA in fibroblasts
25. TNF-α stimulation of fibroblast proliferation dependence on platelet -derived growth factor (PDGF) secretion and alternation of PDGF receptor expression
26. Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts
27. Regulation of human lung fibroblast collagen production by recombinant interleukin-1, tumor necrosis factor, and interferon-γ
28. Differential regulation of the expression of proteinases/antiproteinases in fibroblasts
29. Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis
30. Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice
31. The biology of platelet-derived growth factor
32. Chemotactic activity of platelet alpha granile proteins for fibroblasts
33. Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor
34. Interleukin-1induces the accumulation of cytosolic phospholipase A2 and the release of prostaglandin E2 in human fibroblasts
35. Synergistic stimulasion of fibroblast prostaglandine production by recombinant interleukin 1 and tumor necrosis factor
36. Interleukin-1 enhances the response of osteoblasts to platelet-derived growth factor through the receptor-specific up-regulation
37. Induction of fibroblast growth factor receptor-1 mRNA and protein by platelet-derived growth factor bb