Monosodium urate and calcium pyrophosphate dihydrate (CPPD) crystals, inflammation, and cellular signaling

Joint Bone Spine

Volumn 72, Issue 4, 2005, Pages 295-302

  Liu Bryan, Ru ^a   Lioté, Frédéric ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTRE VIGGO PETERSEN   (France)

Author keywords

Arthritis; Calcium pyrophosphate dihydrate; Cellular signaling; Crystal; Inflammation; Monosodium urate

Indexed keywords

CALCIUM PYROPHOSPHATE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROSTANOID; PROTEIN TYROSINE KINASE; PROTEINASE; URATE;

BONE LESION; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL ACTIVATION; CELL TYPE; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; FIBROBLAST; HUMAN; INFLAMMATION; LEUKOCYTE ACTIVATION; MACROPHAGE; MONOCYTE; NEUTROPHIL; REVIEW; SIGNAL TRANSDUCTION; SYNOVITIS;

EID: 22344446188     PISSN: 1297319X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbspin.2004.12.010     Document Type: Short Survey

References (88)

1. R. Terkeltaub Pathogenesis and treatment of crystal-induced inflammation W. Koopman Arthritis and allied conditions 2001 Lippincott Williams and Wilkins Philadelphia 2329 2347
2. D. McCarty Crystals and arthritis Dis. Mon. 6 1994 255 299
3. R. Terkeltaub Gout and mechanisms of crystal-induced inflammation Curr. Opin. Rheumatol. 5 1993 510 516
4. T. Gordon, R. Terkeltaub, and M. Ginsberg Gout: Crystal-induced inflammation J. Gallin I. Goldstein R. Snyderman Inflammation: basic principles and clinical correlates 1988 Raven New York 775
5. S. McColl, and P. Naccache Crystal-induced arthropathies J. Gallin R. Snyderman Inflammation: basic principles and clinical correlates 1999 Williams and Wilkins Philadelphia 1039 1046
6. P. Guerne, R. Terkeltaub, B. Zuraw, and M. Lotz Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes Arthritis Rheum. 32 1989 1443 1452
7. R. Terkeltaub, C. Zachariae, D. Santoro, J. Martin, P. Peveri, and K. Matsushima Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potent mediator of crystal-induced inflammation Arthritis Rheum. 34 1991 894 903
8. M. Hachicha, P. Naccache, and S. McColl Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin-8 by human neutrophils: a possible mechanism of neutrophil recruitment to sites of inflammation in synovitis J. Exp. Med. 182 1995 2019 2025
9. E. Miller, and W. Brelsford Interleukin 8: the major neutrophil chemotaxin in a case of pseudogout J. Rheumatol. 20 1993 1250 1251
10. R. Terkeltaub, S. Baird, P. Searas, R. Santiago, and W. Boisvert The murine homolog of the interleukin-8 receptor CXCR2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis Arthritis Rheum. 41 1998 900 909
11. A. Nishimura, T. Akahoshi, M. Takahashi, K. Takagishi, M. Itoman, and H. Kondo Attenuation of monosodium urate crystals-induced arthritis in rabbits by a neutralizing antibody against interleukin-8 J. Leukoc. Biol. 62 1997 444 449
12. R. Liu, M. O'Connell, K. Johnson, K. Pritzker, N. Mackman, and R. Terkeltaub ERK-1/ERK-2 mitogen activated protein kinase signaling and activation of activator protein-1 and nuclear factor-kB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate dehydrate crystals in monocytic cells Arthritis Rheum. 43 2000 1145 1155
13. R. Liu, K. Aupperle, and R. Terkeltaub Src family protein tyrosine kinase signaling mediates monosodium urate crystal-induced IL-8 expression by monocytic THP-1 cells J. Leukoc. Biol. 70 2001 961 968
14. R. Hoch, I. Schraufstatter, and C. Cochrane In vivo, in vitro, and molecular aspects of interleukin-8 and the interlrukin-8 receptors J. Lab. Clin. Med. 128 1996 134 145
15. P. Detmers, S. Lo, E. Olsen-Egbert, A. Walz, M. Baggiolini, and Z. Cohn Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils J. Exp. Med. 171 1990 1155 1162
16. A. Matsukawa, T. Yoshimura, T. Maeda, S. Ohkawara, K. Takagi, and M. Yoshinaga Neutrophil accumulation and activation by homologous IL-8 in rabbits: IL-8 induces destruction of cartilage and production of IL-1 and IL-1 receptor antagonist in vivo J. Immunol. 154 1995 5418 5425
17. A. Nishimura, T. Akahoshi, M. Takahashi, K. Takagishi, M. Itoman, and H. Kondo Attenuation of monosodium urate crystal-induced arthritis in rabbits by a neutralizing antibody against interleukin-8 J. Leukoc. Biol. 62 1997 444 449
18. J. Roth, T. Vogl, C. Sorg, and C. Sunderkotter Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules Trends Immunol. 24 2003 155 158
19. C. Ryckman, C. Gilbert, R. De Ḿdicis, A. Lussier, K. Vandal, and P.A. Tessier Monosodium urate monohydrate crystals induce the release of the proinflammatory protein S100A8/A9 from neutrophils J. Leukoc. Biol. 76 2004 433 440
20. C. Ryckman, S. McColl, K. Vandal, R. de Ḿdicis, A. Lussier, and P. Poubelle Role of S100A8 and S100A9 in neutrophil recruitment in response to monosodium urate monohydrate crystals in the air-pouch model of acute gouty arthritis Arthritis Rheum. 48 2003 2310 2320
21. M.P. Manitz, B. Horst, S. Seeliger, A. Strey, B.V. Skryabin, and M. Gunzer Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro Mol. Cell. Biol. 23 2003 1034 1043
22. H. Ginsberg, F. Kozin, D. Chow, J. May, and J.L. Skosey Adsorption of polymorphonuclear leukocytes lysosomal enzymes to urate crystals Arthritis Rheum. 18 1977 1538 1542
23. L. Simchowitz, J.P. Atkinson, and I. Spilberg Stimulation of the respiratory burst in human neutrophils by crystals phagocytosis Arthritis Rheum. 25 1982 181 188
24. S. Abramson, S.T. Hoffstein, and G. Weissmann Superoxide anion generation by human neutrophils exposed to monosodium urate Arthritis Rheum. 25 1982 174 180
25. C.N. Serhan, U. Lindberg, G. Weissmann, and B. Samuelsson Formation of leukotrienes and hydroxy acids by human leukocytes exposed to monosodium urate Prostaglandines 27 1984 563 581
26. P.E. Poubelle, R. de Ḿdicis, and P.H. Naccache Monosodium urate and calcium pyrophosphate crystals differentially activate the excitation-coupling sequence of human neutrophils Biochem. Biophys. Res. Commun. 149 1987 649 657
27. C.J. Roberge, R. de Ḿdicis, J.M. Dayer, M. Rola-Pleszczynski, P.H. Naccache, and P.E. Poubelle Crystal-induced neutrophil activation. IV. Differential production of biologically activate IL-1 and IL-1 receptor antagonist J. Immunol. 152 1994 5485 5494
28. J.S. Bomalaski, and D.G. Baker Brophy LM, Clark MA. Monosodium urate crystals stimulate phospholipase A2 enzyme activities and the synthesis of a phospholipase A2-activating protein J. Immunol. 145 1990 3391 3397
29. P.H. Naccache, S. Bourgoin, E. Plante, G.J. Roberge, R. de Ḿdicis, and A. Lussier Crystal-induced neutrophil activation. II. Evidence for the activation of phosphatidylcholine-specific phospholipase D Arthritis Rheum. 36 1993 117 125
30. R.A. Terkeltaub, L.A. Sklar, and H. Mueller Neutrophil activation by inflammatory microcrystals of monosodium urate monohydrate utilizes pertussis toxin-insensitive and -sensitive pathways J. Immunol. 144 1990 2719 2724
31. P.H. Naccache, M. Grimard, G.J. Roberge, C. Gilbert, A. Lussier, and R. de Ḿdicis Crystal-induced neutrophil activation. I. Initiation and modulation of calcium mobilization and superoxide production by microcrystals Arthritis Rheum. 33 1991 333 342
32. E. Onello, A. Traynor-Kaplan, L. Sklar, and R. Terkeltaub Mechanism of neutrophil activation by an unopsonized inflammatory particulate. Monosodium urate crystals induce pertussis toxin-insensitive hydrolysis of phosphatidylinositol 4,5-bisphosphate J. Immunol. 146 1991 4289 4294
33. C. Gilbert, P.E. Poubelle, P. Borgeat, M. Pouliot, and P.H. Naccache Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals Arthritis Rheum. 48 2003 1137 1148
34. M. Gaudry, C.J. Roberge, R. de Ḿdicis, A. Lussier, P.E. Poubelle, and P.H. Naccache Crystal-induced neutrophil activation. III. Inflammatory microcrystals induce a distinct pattern of tyrosine phosphorylation by human neutrophils J. Clin. Invest. 91 1993 1649 1655
35. C.J. Roberge, M. Gaudry, R. de Ḿdicis, A. Lussier, P.E. Poubelle, and P.H. Naccache Crystal-induced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine J. Clin. Invest. 92 1993 1722 1729
36. H. Burt, J.K. Jackson, P. Dryden, and H. Salari Crystal-induced protein tyrosine phosphorylation in neutrophils and the effect of a tyrosine kinase inhibitor on neutrophil responses Mol. Pharmacol. 43 1993 30 46
37. F. Barabe, C. Gillbert, N. Liao, S.G. Bourgoin, and P.H. Naccache Crystal-induced neutrophil activation.VI. Involvement of Fc gamma RIIIB (CD16) and CD11b in response to inflammatory microcrystals FASEB J. 12 1998 209 220
38. M. Gaudry, C. Gillbert, F. Barabe, P.E. Poubelle, and P.H. Naccache Activation of Lyn is a common element of the stimulation of human neutrophils by soluble and particulate agonists Blood 86 1995 3567 3574
39. P. Desaulniers, M. Fernandes, C. Gilbert, S.G. Bourgoin, and P.H. Naccache Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals J. Leukoc. Biol. 70 2001 659 668
40. J. Jackson, C. Tudan, and H. Burt The involvement of phospholipase C in crystal-induced human neutrophil activation J. Rheumatol. 27 2000 2877 2885
41. J. Jackson, R. Lauener, V. Duronio, and H. Burt The involvement of phosphatidylinositol 3-kinase in crystal induced human neutrophil activation J. Rheumatol. 24 1997 341 348
42. C. Gilbert, F. Barabe, E. Rollet-labelle, S.G. Bourgoin, S.R. McColl, and B. Damaj Evidence for a role of SAM68 in the responses of human neutrophils to ligation of CD32 and to monosodium urate crystals J. Immunol. 166 2001 4664 4671
43. C. Tudan, J. Jackson, L. Charlton, S.L. Pelech, B. Sahl, and H. Burt Activation of S6 kinase in human neutrophils by calcium pyrophosphate dihydrate crystals: protein kinase C-dependent and phosphatidylinositol 3-kinase-independent pathways Biochem. J. 331 1998 531 537
44. M.K. Whyte, J. Savill, L.C. Meagher, A. Lee, and C. Haslett Coupling of neutrophil apoptosis to recognition by macrophages: coordinated acceleration by protein synthesis inhibitors J. Leukoc. Biol. 62 1997 195 202
45. C. Haslett Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes Clin. Sci. 83 1992 639 648
46. M.B. Hallett, and D. Lloyds Neutrophil priming: the cellular signals that say "amber" not "green" Immunol. Today 16 1995 264
47. C. Tudan, J.K. Jackson, L. Blanis, S.L. Pelech, and H.M. Burt Inhibition of TNF-alpha-induced neutrophil apoptosis by crystals of calcium pyrophosphate dihydrate is mediated by the extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways up-stream of caspase 3 J. Immunol. 165 2000 5798 5806
48. C. Tudan, D. Fong, V. Duronio, H.M. Burt, and J.K. Jackson The inhibition of spontaneous and tumor necrosis factor-alpha induced neutrophil apoptosis by crystals of calcium pyrophosphate dihydrate and monosodium urate monohydrate J. Rheumatol. 27 2000 2463 2472
49. J.K. Jackson, C. Tudan, B. Sahl, S. Pelech, and H.M. Burt Calcium pyrophosphate dihydrate crystals activate MAP kinase in human neutrophils: inhibition of MAP kinase, oxidase activation and degranulation responses of neutrophils by taxol Immunology 90 1997 502 510
50. E. Berra, M.T. Diaz-Meco, and J. Moscat The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway J. Biol. Chem. 273 1998 10792 10797
51. G.W. Duff, E. Atkins, and S.E. Malawista The fever of gout: urate crystals activate endogenous pyrogen production from human and rabbit mononuclear phagocytes Trans. Assoc. Am. Physicians 96 1983 234 245
52. F.S. Di Giovine, S.E. Malawista, E. Thornton, and G.W. Duff Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution J. Clin. Invest. 87 1991 1375 1381
53. P.T. Chapman, H. Yarwood, A.A. Harrison, C.J. Stocker, F. Jamar, and R.H. Gundel Endothelial activation in monosodium urate monohydrate crystal-induced inflammation: in vitro and in vivo studies on the roles of tumor necrosis factor alpha and interleukin-1 Arthritis Rheum. 40 1997 955 965
54. P.T. Chapman, F. Jamar, A.A. Harrison, R.M. Binns, A.M. Peters, and D.O. Haskard Noninvasive imaging of E-selectin expression by activated endothelium in urate crystal-induced arthritis Arthritis Rheum. 37 1994 1752 1756
55. P.T. Chapman, F. Jamar, A.A. Harrison, J.B. Schofield, A.M. Peters, and R.M. Binns Characterization of E-selectin expression, leucocyte traffic and clinical sequelae in urate crystal-induced inflammation: an insight into gout Br. J. Rheumatol. 35 1996 323 334
56. J.E. Seegmiller, and R.R. Howell The inflammatory reaction to sodium urate J. Am. Med. Assoc. 180 1962 469 475
57. E. Pascual, and V. Jovani A quantitative study of the phagocytosis of urate crystals in the synovial fluid of asymptomatic joints of patients with gout Br. J. Rheumatol. 34 1995 724 726
58. D.R. Yagnik, P. Hillyer, D. Marshall, C.D. Smythe, T. Krausz, and D.O. Haskard Noninflammatory phagocytosis of monosodium urate monohydrate crystals by mouse macrophages. Implications for the control of joint inflammation in gout Arthritis Rheum. 43 2000 1779 1789
59. R.C. Landis, D.R. Yagnik, O. Florey, P. Philippidis, V. Emons, and J.C. Mason Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages Arthritis Rheum. 46 2002 3026 3033
60. D.O. Haskard, and R.C. Landis Interactions between leukocytes and endothelial cells in gout: lessons from a self-limiting inflammatory response Arthritis Res. 4 2002 S91 S97
61. C.K. Glass Potential roles of the peroxisome proliferator-activated receptor-gamma in macrophage biology and atherosclerosis J. Endocrinol. 169 2001 461 464
62. T. Akahoshi, R. Namai, Y. Murakami, M. Watanabe, T. Matsui, and A. Nishimura Rapid induction of peroxisome proliferator-activated receptor gamma expression in human monocytes by monosodium urate monohydrate crystals Arthritis Rheum. 48 2003 231 239
63. M. Pouliot, M.J. James, S.R. McColl, P.H. Naccache, and L.G. Cleland Monosodium urate microcrystals induce cyclooxygenase-2 in human monocytes Blood 91 1998 1769 1776
64. J.Y. Fu, J.L. Masferrer, K. Seibert, A. Raz, and P. Needleman The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes J. Biol. Chem. 265 1990 16737 16740
65. S.L. Smith, P. Borgeat, and F.A. Fitzpatrick The eicosanoids: cyclooxygenase, lipoxygenase and epoxygenase pathways D.E. Vance J. Vance Biochemistry of lipids, lipoproteins and membranes 1991 Elsevier New York, NY 297
66. M.K. Urban COX-2 specific inhibitors offer improved advantages over traditional NSAIDs Orthopedics 23 2000 S761 S764
67. M.T. Nurmohamed, V.P. van Halm, and B.A. Dijkmans Cardiovascular risk profile of antirheumatic agents in patients with osteoarthritis and rheumatoid arthritis Drugs 62 2002 1599 1609
68. M. Kagoshima, K. Ito, B. Cosio, and I.M. Adcock Glucocorticoid suppression of nuclear factor-kappa B: a role for histone modifications Biochem. Soc. Trans. 31 2003 60 65
69. M.G. Belvisi, T.J. Brown, S. Wicks, and M.L. Foster New glucocorticosteroids with an improved therapeutic ratio? Pulm. Pharmacol. Ther. 14 2001 221 227
70. Y. Molad Update on colchicine and its mechanism of action Curr. Rheumatol. Rep. 4 2002 252 256
71. K.T. Rott, and C.A. Agudelo Gout J. Am. Med. Assoc. 289 2003 2857 2860
72. G.M. McCarthy, C.R. Barthelemy, J.A. Veum, and R.L. Wortmann Influence of antihyperuricemic therapy on the clinical and radiographic progression of gout Arthritis Rheum. 34 1991 1489 1494
73. R. Liu, F. Liot́, D.M. Rose, D. Merz, and R. Terkeltaub Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes Arthritis Rheum. 50 2004 247 258
74. A.H. Baker, D.R. Edwards, and G. Murphy Metalloproteinase inhibitors: biological actions and therapeutic opportunities J. Cell Sci. 115 2002 3719 3727
75. M. Goldring The role of the chondrocyte in osteoarthritis Arthritis Rheum. 43 2000 1916 1926
76. R.M.J. Palmer, M.S. Hickery, I.G. Charles, S. Moncada, and M.T. Bayliss Induction of inducible nitric oxide synthase in human chondrocytes Biochem. Biophys. Res. Commun. 193 1993 398 405
77. D. Taskiran, M. Stefanovic-Racic, H.I. Georgescu, and C.H. Evans Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1 Biochem. Biophys. Res. Commun. 200 1994 142 148
78. F.J. Blanco, R.L. Ochs, H. Schwarz, and M. Lotz Chondrocyte apoptosis induced by nitric oxide Am. J. Pathol. 146 1995 75 85
79. G.A. Murrell, D. Jang, and R.J. Williams Nitric oxide activates metalloprotease enzymes in articular cartilage Biochem. Biophys. Res. Commun. 206 1995 15 21
80. Z. Gu, M. Kaul, B. Yan, S.J. Kridel, J. Cui, and A. Strongin S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death Science 297 2002 1186 1190
81. D.D. Schlaepfer, C.R. Hauck, and D.J. Sieg Signaling through focal adhesion kinase Prog. Biophys. Mol. Biol. 71 1999 435 478
82. P. Hasselbacher Stimulation of synovial fibroblasts by calcium oxalate and monosodium urate monohydrate. A mechanism of connective tissue degradation in oxalosis and gout J. Lab. Clin. Med. 100 1982 977 985
83. M.S. Hsieh, H.C. Ho, D.T. Chou, S. Pan, Y.C. Liang, and T.Y. Hsieh Expression of matrix metalloproteinase-9 (gelatinase B) in gouty arthritis and stimulation of MMP-9 by urate crystals in macrophages J. Cell. Biochem. 89 2003 791 799
84. H.S. Cheung, T.R. Devine, and W. Hubbard Calcium phosphate particle induction of metalloproteinase and mitogenesis: effect of particle sizes Osteoarthritis Cartilage 5 1997 145 151
85. D. Nair, R.P. Misra, J.D. Sallis, and H.S. Cheung Phosphocitrate inhibits a basic calcium phosphate and calcium pyrophosphate dihydrate crystal-induced mitogen-activated protein kinase cascade signal transduction pathway J. Biol. Chem. 272 1997 18920 18925
86. H.S. Cheung, J.D. Sallis, and J.A. Struve Specific inhibition of basic calcium phosphate and calcium pyrophosphate crystal-induction of metalloproteinase synthesis by phosphocitrate Biochim. Biophys. Acta 1315 1996 105 111
87. L. Bouchard, R. de Ḿdicis, A. Lussier, P.H. Naccache, and P.E. Poubelle Inflammatory microcrystals alter the functional phenotype of human osteoblast-like cells in vitro: synergism with IL-1 to overexpress cyclooxygenase-2 J. Immunol. 168 2002 5310 5317
88. S. Elliott, and T. Cawston The clinical potential of matrix metalloproteinase inhibitors in the rheumatic disorders Drugs Aging 18 2001 87 99