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Volumn 117, Issue 1, 2008, Pages 30-51

Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies

Author keywords

Antidepressant drugs; BDNF; Depression; Electroconvulsive treatment; Mood disorders; TrkB

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; METHIONINE;

EID: 36549089541     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2007.07.001     Document Type: Review
Times cited : (183)

References (209)
  • 1
    • 0037314177 scopus 로고    scopus 로고
    • Antidepressants: update on new agents and indications
    • Ables A.Z., and Baughman O.L. Antidepressants: update on new agents and indications. Am Fam Physician 67 (2003) 547-554
    • (2003) Am Fam Physician , vol.67 , pp. 547-554
    • Ables, A.Z.1    Baughman, O.L.2
  • 2
    • 1542380913 scopus 로고    scopus 로고
    • Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression
    • Adlard P.A., and Cotman C.W. Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression. Neuroscience 124 (2004) 985-992
    • (2004) Neuroscience , vol.124 , pp. 985-992
    • Adlard, P.A.1    Cotman, C.W.2
  • 3
    • 2442475297 scopus 로고    scopus 로고
    • The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise
    • Adlard P.A., Perreau V.M., Engesser-Cesar C., and Cotman C.W. The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise. Neurosci Lett 363 (2004) 43-48
    • (2004) Neurosci Lett , vol.363 , pp. 43-48
    • Adlard, P.A.1    Perreau, V.M.2    Engesser-Cesar, C.3    Cotman, C.W.4
  • 4
    • 0030995057 scopus 로고    scopus 로고
    • TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death
    • Alcantara S., Frisen J., del Rio J.A., Soriano E., Barbacid M., and Silos-Santiago I. TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J Neurosci 17 (1997) 3623-3633
    • (1997) J Neurosci , vol.17 , pp. 3623-3633
    • Alcantara, S.1    Frisen, J.2    del Rio, J.A.3    Soriano, E.4    Barbacid, M.5    Silos-Santiago, I.6
  • 5
    • 32144437619 scopus 로고    scopus 로고
    • Regulation of hippocampal gene expression is conserved in two species subjected to different stressors and antidepressant treatments
    • Alfonso J., Frick L.R., Silberman D.M., Palumbo M.L., Genaro A.M., and Frasch A.C. Regulation of hippocampal gene expression is conserved in two species subjected to different stressors and antidepressant treatments. Biol Psychiatry 59 (2006) 244-251
    • (2006) Biol Psychiatry , vol.59 , pp. 244-251
    • Alfonso, J.1    Frick, L.R.2    Silberman, D.M.3    Palumbo, M.L.4    Genaro, A.M.5    Frasch, A.C.6
  • 6
    • 0033079596 scopus 로고    scopus 로고
    • Neurotrophins and depression
    • Altar C.A. Neurotrophins and depression. Trends Pharmacol Sci 20 (1999) 59-61
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 59-61
    • Altar, C.A.1
  • 7
    • 0028592632 scopus 로고
    • The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra
    • Altar C.A., Boylan C.B., Fritsche M., Jackson C., Hyman C., and Lindsay R.M. The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra. Exp Neurol 130 (1994) 31-40
    • (1994) Exp Neurol , vol.130 , pp. 31-40
    • Altar, C.A.1    Boylan, C.B.2    Fritsche, M.3    Jackson, C.4    Hyman, C.5    Lindsay, R.M.6
  • 8
    • 0142040220 scopus 로고    scopus 로고
    • Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain
    • Altar C.A., Whitehead R.E., Chen R., Wortwein G., and Madsen T.M. Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain. Biol Psychiatry 54 (2003) 703-709
    • (2003) Biol Psychiatry , vol.54 , pp. 703-709
    • Altar, C.A.1    Whitehead, R.E.2    Chen, R.3    Wortwein, G.4    Madsen, T.M.5
  • 9
    • 1842557854 scopus 로고    scopus 로고
    • Expression analysis of brain-derived neurotrophic factor (BDNF) mRNA isoforms after chronic and acute antidepressant treatment
    • Altieri M., Marini F., Arban R., Vitulli G., and Jansson B.O. Expression analysis of brain-derived neurotrophic factor (BDNF) mRNA isoforms after chronic and acute antidepressant treatment. Brain Res 1000 (2004) 148-155
    • (2004) Brain Res , vol.1000 , pp. 148-155
    • Altieri, M.1    Marini, F.2    Arban, R.3    Vitulli, G.4    Jansson, B.O.5
  • 10
    • 0036399811 scopus 로고    scopus 로고
    • Electroconvulsive stimuli alter the regional concentrations of nerve growth factor, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in adult rat brain
    • Angelucci F., Aloe L., Jimenez-Vasquez P., and Mathe A.A. Electroconvulsive stimuli alter the regional concentrations of nerve growth factor, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in adult rat brain. J ECT 18 (2002) 138-143
    • (2002) J ECT , vol.18 , pp. 138-143
    • Angelucci, F.1    Aloe, L.2    Jimenez-Vasquez, P.3    Mathe, A.A.4
  • 11
    • 0035988615 scopus 로고    scopus 로고
    • Toward molecular diagnostics of mood disorders in psychiatry
    • Avissar S., and Schreiber G. Toward molecular diagnostics of mood disorders in psychiatry. Trends Mol Med 8 (2002) 294-300
    • (2002) Trends Mol Med , vol.8 , pp. 294-300
    • Avissar, S.1    Schreiber, G.2
  • 12
    • 13444273349 scopus 로고    scopus 로고
    • The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study
    • Aydemir O., Deveci A., and Taneli F. The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study. Prog Neuropsychopharmacol Biol Psychiatry 29 (2005) 261-265
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 261-265
    • Aydemir, O.1    Deveci, A.2    Taneli, F.3
  • 13
    • 33746048845 scopus 로고    scopus 로고
    • BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions
    • Bamji S.X., Rico B., Kimes N., and Reichardt L.F. BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions. J Cell Biol 174 (2006) 289-299
    • (2006) J Cell Biol , vol.174 , pp. 289-299
    • Bamji, S.X.1    Rico, B.2    Kimes, N.3    Reichardt, L.F.4
  • 14
    • 0020338405 scopus 로고
    • Purification of a new neurotrophic factor from mammalian brain
    • Barde Y.A., Edgar D., and Thoenen H. Purification of a new neurotrophic factor from mammalian brain. EMBO J 1 (1982) 549-553
    • (1982) EMBO J , vol.1 , pp. 549-553
    • Barde, Y.A.1    Edgar, D.2    Thoenen, H.3
  • 15
    • 0038452619 scopus 로고    scopus 로고
    • Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways
    • Barnabe-Heider F., and Miller F.D. Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways. J Neurosci 23 (2003) 5149-5160
    • (2003) J Neurosci , vol.23 , pp. 5149-5160
    • Barnabe-Heider, F.1    Miller, F.D.2
  • 16
    • 0036257944 scopus 로고    scopus 로고
    • Manic-depression genes and the new millennium: poised for discovery
    • Baron M. Manic-depression genes and the new millennium: poised for discovery. Mol Psychiatry 7 (2002) 342-358
    • (2002) Mol Psychiatry , vol.7 , pp. 342-358
    • Baron, M.1
  • 17
    • 0033821342 scopus 로고    scopus 로고
    • Antidepressant drug exposure is associated with mRNA levels of tyrosine receptor kinase B in major depressive disorder
    • Bayer T.A., Schramm M., Feldmann N., Knable M.B., and Falkai P. Antidepressant drug exposure is associated with mRNA levels of tyrosine receptor kinase B in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 24 (2000) 881-888
    • (2000) Prog Neuropsychopharmacol Biol Psychiatry , vol.24 , pp. 881-888
    • Bayer, T.A.1    Schramm, M.2    Feldmann, N.3    Knable, M.B.4    Falkai, P.5
  • 19
    • 0027520886 scopus 로고
    • Regulation of neurotrophin and trkA, TrkB and trkC tyrosine kinase receptor messenger RNA expression in kindling
    • Bengzon J., Kokaia Z., Ernfors P., Kokaia M., Leanza G., Nilsson O.G., et al. Regulation of neurotrophin and trkA, TrkB and trkC tyrosine kinase receptor messenger RNA expression in kindling. Neuroscience 53 (1993) 433-446
    • (1993) Neuroscience , vol.53 , pp. 433-446
    • Bengzon, J.1    Kokaia, Z.2    Ernfors, P.3    Kokaia, M.4    Leanza, G.5    Nilsson, O.G.6
  • 20
    • 0029086255 scopus 로고
    • Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system
    • Berhow M.T., Russell D.S., Terwilliger R.Z., Beitner-Johnson D., Self D.W., Lindsay R.M., et al. Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system. Neuroscience 68 (1995) 969-979
    • (1995) Neuroscience , vol.68 , pp. 969-979
    • Berhow, M.T.1    Russell, D.S.2    Terwilliger, R.Z.3    Beitner-Johnson, D.4    Self, D.W.5    Lindsay, R.M.6
  • 21
    • 0032423613 scopus 로고    scopus 로고
    • What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
    • Berridge K.C., and Robinson T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?. Brain Res Brain Res Rev 28 (1998) 309-369
    • (1998) Brain Res Brain Res Rev , vol.28 , pp. 309-369
    • Berridge, K.C.1    Robinson, T.E.2
  • 22
    • 0029045809 scopus 로고
    • Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development
    • Biffo S., Offenhauser N., Carter B.D., and Barde Y.A. Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development. Development 121 (1995) 2461-2470
    • (1995) Development , vol.121 , pp. 2461-2470
    • Biffo, S.1    Offenhauser, N.2    Carter, B.D.3    Barde, Y.A.4
  • 25
    • 0018415406 scopus 로고
    • Chronic response of rat brain norepinephrine and serotonin levels to endurance training
    • Brown B.S., Payne T., Kim C., Moore G., Krebs P., and Martin W. Chronic response of rat brain norepinephrine and serotonin levels to endurance training. J Appl Physiol 46 (1979) 19-23
    • (1979) J Appl Physiol , vol.46 , pp. 19-23
    • Brown, B.S.1    Payne, T.2    Kim, C.3    Moore, G.4    Krebs, P.5    Martin, W.6
  • 27
    • 0742271349 scopus 로고    scopus 로고
    • Neurotrophic effects of antidepressant drugs
    • Castren E. Neurotrophic effects of antidepressant drugs. Curr Opin Pharmacol 4 (2004) 58-64
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 58-64
    • Castren, E.1
  • 28
    • 0027454035 scopus 로고
    • Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain
    • Castren E., da Penha B.M., Lindholm D., and Thoenen H. Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain. Exp Neurol 122 (1993) 244-252
    • (1993) Exp Neurol , vol.122 , pp. 244-252
    • Castren, E.1    da Penha, B.M.2    Lindholm, D.3    Thoenen, H.4
  • 30
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B., Dowlatshahi D., MacQueen G.M., Wang J.F., and Young L.T. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 50 (2001) 260-265
    • (2001) Biol Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3    Wang, J.F.4    Young, L.T.5
  • 31
    • 33749649795 scopus 로고    scopus 로고
    • Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
    • Chen Z.Y., Jing D., Bath K.G., Ieraci A., Khan T., Siao C.J., et al. Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 314 (2006) 140-143
    • (2006) Science , vol.314 , pp. 140-143
    • Chen, Z.Y.1    Jing, D.2    Bath, K.G.3    Ieraci, A.4    Khan, T.5    Siao, C.J.6
  • 32
    • 0000050472 scopus 로고
    • A nerve growth-stimulating factor isolated from sarcoma as 37 and 180
    • Cohen S., Levi-Montalcini R., and Hamburger V. A nerve growth-stimulating factor isolated from sarcoma as 37 and 180. Proc Natl Acad Sci U S A 40 (1954) 1014-1018
    • (1954) Proc Natl Acad Sci U S A , vol.40 , pp. 1014-1018
    • Cohen, S.1    Levi-Montalcini, R.2    Hamburger, V.3
  • 33
    • 0037410392 scopus 로고    scopus 로고
    • Bi-phasic change in BDNF gene expression following antidepressant drug treatment
    • Coppell A.L., Pei Q., and Zetterstrom T.S. Bi-phasic change in BDNF gene expression following antidepressant drug treatment. Neuropharmacology 44 (2003) 903-910
    • (2003) Neuropharmacology , vol.44 , pp. 903-910
    • Coppell, A.L.1    Pei, Q.2    Zetterstrom, T.S.3
  • 34
    • 0037688084 scopus 로고    scopus 로고
    • Finding the intracellular signaling pathways affected by mood disorder treatments
    • Coyle J.T., and Duman R.S. Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron 38 (2003) 157-160
    • (2003) Neuron , vol.38 , pp. 157-160
    • Coyle, J.T.1    Duman, R.S.2
  • 35
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: recent developments and future needs
    • Cryan J.F., Markou A., and Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci 23 (2002) 238-245
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 238-245
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 36
    • 2542602316 scopus 로고    scopus 로고
    • Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors
    • Cryan J.F., O'Leary O.F., Jin S.H., Friedland J.C., Ouyang M., Hirsch B.R., et al. Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. Proc Natl Acad Sci U S A 101 (2004) 8186-8191
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8186-8191
    • Cryan, J.F.1    O'Leary, O.F.2    Jin, S.H.3    Friedland, J.C.4    Ouyang, M.5    Hirsch, B.R.6
  • 37
    • 4644271811 scopus 로고    scopus 로고
    • Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment
    • De Foubert G., Carney S.L., Robinson C.S., Destexhe E.J., Tomlinson R., Hicks C.A., et al. Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment. Neuroscience 128 (2004) 597-604
    • (2004) Neuroscience , vol.128 , pp. 597-604
    • De Foubert, G.1    Carney, S.L.2    Robinson, C.S.3    Destexhe, E.J.4    Tomlinson, R.5    Hicks, C.A.6
  • 38
    • 0026495421 scopus 로고
    • Exercise training: significance of regional alterations in serotonin metabolism of rat brain in relation to antidepressant effect of exercise
    • Dey S., Singh R.H., and Dey P.K. Exercise training: significance of regional alterations in serotonin metabolism of rat brain in relation to antidepressant effect of exercise. Physiol Behav 52 (1992) 1095-1099
    • (1992) Physiol Behav , vol.52 , pp. 1095-1099
    • Dey, S.1    Singh, R.H.2    Dey, P.K.3
  • 39
    • 0042196550 scopus 로고    scopus 로고
    • Differential regulation of brain derived neurotrophic factor transcripts by antidepressant treatments in the adult rat brain
    • Dias B.G., Banerjee S.B., Duman R.S., and Vaidya V.A. Differential regulation of brain derived neurotrophic factor transcripts by antidepressant treatments in the adult rat brain. Neuropharmacology 45 (2003) 553-563
    • (2003) Neuropharmacology , vol.45 , pp. 553-563
    • Dias, B.G.1    Banerjee, S.B.2    Duman, R.S.3    Vaidya, V.A.4
  • 40
    • 0035058762 scopus 로고    scopus 로고
    • Benefits from aerobic exercise in patients with major depression: a pilot study
    • Dimeo F., Bauer M., Varahram I., Proest G., and Halter U. Benefits from aerobic exercise in patients with major depression: a pilot study. Br J Sports Med 35 (2001) 114-117
    • (2001) Br J Sports Med , vol.35 , pp. 114-117
    • Dimeo, F.1    Bauer, M.2    Varahram, I.3    Proest, G.4    Halter, U.5
  • 41
    • 0034662246 scopus 로고    scopus 로고
    • Treadmill exercise training augments brain norepinephrine response to familiar and novel stress
    • Dishman R.K., Renner K.J., White-Welkley J.E., Burke K.A., and Bunnell B.N. Treadmill exercise training augments brain norepinephrine response to familiar and novel stress. Brain Res Bull 52 (2000) 337-342
    • (2000) Brain Res Bull , vol.52 , pp. 337-342
    • Dishman, R.K.1    Renner, K.J.2    White-Welkley, J.E.3    Burke, K.A.4    Bunnell, B.N.5
  • 42
    • 0037418339 scopus 로고    scopus 로고
    • Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
    • Duan W., Guo Z., Jiang H., Ware M., Li X.J., and Mattson M.P. Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proc Natl Acad Sci U S A 100 (2003) 2911-2916
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2911-2916
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Li, X.J.5    Mattson, M.P.6
  • 43
    • 0031681434 scopus 로고    scopus 로고
    • Novel therapeutic approaches beyond the serotonin receptor
    • Duman R.S. Novel therapeutic approaches beyond the serotonin receptor. Biol Psychiatry 44 (1998) 324-335
    • (1998) Biol Psychiatry , vol.44 , pp. 324-335
    • Duman, R.S.1
  • 44
    • 1642307557 scopus 로고    scopus 로고
    • Role of neurotrophic factors in the etiology and treatment of mood disorders
    • Duman R.S. Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Med 5 (2004) 11-25
    • (2004) Neuromolecular Med , vol.5 , pp. 11-25
    • Duman, R.S.1
  • 45
    • 28444447357 scopus 로고    scopus 로고
    • Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism
    • Duman R.S. Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism. Neurobiol Aging 26 Suppl 1 (2005) 88-93
    • (2005) Neurobiol Aging , vol.26 , Issue.SUPPL. 1 , pp. 88-93
    • Duman, R.S.1
  • 46
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., and Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 59 (2006) 1116-1127
    • (2006) Biol Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 47
    • 0028569188 scopus 로고
    • Molecular psychiatry: adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity
    • Duman R.S., Heninger R.S., and Nestler E.J. Molecular psychiatry: adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity. J Nerv Ment Dis 182 (1994) 692-700
    • (1994) J Nerv Ment Dis , vol.182 , pp. 692-700
    • Duman, R.S.1    Heninger, R.S.2    Nestler, E.J.3
  • 50
    • 0035020808 scopus 로고    scopus 로고
    • Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects
    • Dwivedi Y., Rizavi H.S., Roberts R.C., Conley R.C., Tamminga C.A., and Pandey G.N. Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects. J Neurochem 77 (2001) 916-928
    • (2001) J Neurochem , vol.77 , pp. 916-928
    • Dwivedi, Y.1    Rizavi, H.S.2    Roberts, R.C.3    Conley, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 51
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects
    • Dwivedi Y., Rizavi H.S., Conley R.R., Roberts R.C., Tamminga C.A., and Pandey G.N. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 60 (2003) 804-815
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Roberts, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 52
    • 33646150655 scopus 로고    scopus 로고
    • Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosterone
    • Dwivedi Y., Rizavi H.S., and Pandey G.N. Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosterone. Neuroscience 139 (2006) 1017-1029
    • (2006) Neuroscience , vol.139 , pp. 1017-1029
    • Dwivedi, Y.1    Rizavi, H.S.2    Pandey, G.N.3
  • 53
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112 (2003) 257-269
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3    Goldberg, T.E.4    Kolachana, B.S.5    Bertolino, A.6
  • 54
    • 0242559031 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression
    • Eisch A.J., Bolanos C.A., de Wit J., Simonak R.D., Pudiak C.M., Barrot M., et al. Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biol Psychiatry 54 (2003) 994-1005
    • (2003) Biol Psychiatry , vol.54 , pp. 994-1005
    • Eisch, A.J.1    Bolanos, C.A.2    de Wit, J.3    Simonak, R.D.4    Pudiak, C.M.5    Barrot, M.6
  • 55
    • 0442307920 scopus 로고    scopus 로고
    • Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo
    • Farmer J., Zhao X., van Praag H., Wodtke K., Gage F.H., and Christie B.R. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 124 (2004) 71-79
    • (2004) Neuroscience , vol.124 , pp. 71-79
    • Farmer, J.1    Zhao, X.2    van Praag, H.3    Wodtke, K.4    Gage, F.H.5    Christie, B.R.6
  • 56
    • 0032805204 scopus 로고    scopus 로고
    • BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies
    • Ferrer I., Marin C., Rey M.J., Ribalta T., Goutan E., Blanco R., et al. BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies. J Neuropathol Exp Neurol 58 (1999) 729-739
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 729-739
    • Ferrer, I.1    Marin, C.2    Rey, M.J.3    Ribalta, T.4    Goutan, E.5    Blanco, R.6
  • 58
    • 0033991319 scopus 로고    scopus 로고
    • Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus
    • Fujimaki K., Morinobu S., and Duman R.S. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology 22 (2000) 42-51
    • (2000) Neuropsychopharmacology , vol.22 , pp. 42-51
    • Fujimaki, K.1    Morinobu, S.2    Duman, R.S.3
  • 59
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
    • Fukumoto T., Morinobu S., Okamoto Y., Kagaya A., and Yamawaki S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology (Berl) 158 (2001) 100-106
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 60
    • 0027744156 scopus 로고
    • Seizure-induced changes in neurotrophin expression: implications for epilepsy
    • Gall C.M. Seizure-induced changes in neurotrophin expression: implications for epilepsy. Exp Neurol 124 (1993) 150-166
    • (1993) Exp Neurol , vol.124 , pp. 150-166
    • Gall, C.M.1
  • 61
    • 0038521071 scopus 로고    scopus 로고
    • The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity
    • Garcia C., Chen M.J., Garza A.A., Cotman C.W., and Russo-Neustadt A. The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity. Neuroscience 119 (2003) 721-732
    • (2003) Neuroscience , vol.119 , pp. 721-732
    • Garcia, C.1    Chen, M.J.2    Garza, A.A.3    Cotman, C.W.4    Russo-Neustadt, A.5
  • 63
    • 22144474412 scopus 로고    scopus 로고
    • Partial normalization of serum brain-derived neurotrophic factor in remitted patients after a major depressive episode
    • Gervasoni N., Aubry J.M., Bondolfi G., Osiek C., Schwald M., Bertschy G., et al. Partial normalization of serum brain-derived neurotrophic factor in remitted patients after a major depressive episode. Neuropsychobiology 51 (2005) 234-238
    • (2005) Neuropsychobiology , vol.51 , pp. 234-238
    • Gervasoni, N.1    Aubry, J.M.2    Bondolfi, G.3    Osiek, C.4    Schwald, M.5    Bertschy, G.6
  • 64
    • 0344837823 scopus 로고    scopus 로고
    • Signalling pathways involved in the short-term potentiation of dopamine release by BDNF
    • Goggi J., Pullar I.A., Carney S.L., and Bradford H.F. Signalling pathways involved in the short-term potentiation of dopamine release by BDNF. Brain Res 968 (2003) 156-161
    • (2003) Brain Res , vol.968 , pp. 156-161
    • Goggi, J.1    Pullar, I.A.2    Carney, S.L.3    Bradford, H.F.4
  • 66
    • 0028019114 scopus 로고
    • Neurotrophin-6 is a new member of the nerve growth factor family
    • Gotz R., Koster R., Winkler C., Raulf F., Lottspeich F., Schartl M., et al. Neurotrophin-6 is a new member of the nerve growth factor family. Nature 372 (1994) 266-269
    • (1994) Nature , vol.372 , pp. 266-269
    • Gotz, R.1    Koster, R.2    Winkler, C.3    Raulf, F.4    Lottspeich, F.5    Schartl, M.6
  • 67
    • 0037321303 scopus 로고    scopus 로고
    • Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving
    • Grimm J.W., Lu L., Hayashi T., Hope B.T., Su T.P., and Shaham Y. Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. J Neurosci 23 (2003) 742-747
    • (2003) J Neurosci , vol.23 , pp. 742-747
    • Grimm, J.W.1    Lu, L.2    Hayashi, T.3    Hope, B.T.4    Su, T.P.5    Shaham, Y.6
  • 68
    • 0036175834 scopus 로고    scopus 로고
    • Physical activity to prevent cardiovascular disease. How much is enough?
    • Haennel R.G., and Lemire F. Physical activity to prevent cardiovascular disease. How much is enough?. Can Fam Physician 48 (2002) 65-71
    • (2002) Can Fam Physician , vol.48 , pp. 65-71
    • Haennel, R.G.1    Lemire, F.2
  • 69
    • 0041884826 scopus 로고    scopus 로고
    • Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice
    • Hall F.S., Drgonova J., Goeb M., and Uhl G.R. Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice. Neuropsychopharmacology 28 (2003) 1485-1490
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1485-1490
    • Hall, F.S.1    Drgonova, J.2    Goeb, M.3    Uhl, G.R.4
  • 70
    • 0043135252 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance
    • Hariri A.R., Goldberg T.E., Mattay V.S., Kolachana B.S., Callicott J.H., Egan M.F., et al. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci 23 (2003) 6690-6694
    • (2003) J Neurosci , vol.23 , pp. 6690-6694
    • Hariri, A.R.1    Goldberg, T.E.2    Mattay, V.S.3    Kolachana, B.S.4    Callicott, J.H.5    Egan, M.F.6
  • 71
    • 2442597374 scopus 로고    scopus 로고
    • Critical role of brain-derived neurotrophic factor in mood disorders
    • Hashimoto K., Shimizu E., and Iyo M. Critical role of brain-derived neurotrophic factor in mood disorders. Brain Res Brain Res Rev 45 (2004) 104-114
    • (2004) Brain Res Brain Res Rev , vol.45 , pp. 104-114
    • Hashimoto, K.1    Shimizu, E.2    Iyo, M.3
  • 72
    • 17144446667 scopus 로고    scopus 로고
    • No linkage or linkage disequilibrium between brain-derived neurotrophic factor (BDNF) dinucleotide repeat polymorphism and schizophrenia in Irish families
    • Hawi Z., Straub R.E., O'Neill A., Kendler K.S., Walsh D., and Gill M. No linkage or linkage disequilibrium between brain-derived neurotrophic factor (BDNF) dinucleotide repeat polymorphism and schizophrenia in Irish families. Psychiatry Res 81 (1998) 111-116
    • (1998) Psychiatry Res , vol.81 , pp. 111-116
    • Hawi, Z.1    Straub, R.E.2    O'Neill, A.3    Kendler, K.S.4    Walsh, D.5    Gill, M.6
  • 73
    • 0033562567 scopus 로고    scopus 로고
    • Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor
    • Horger B.A., Iyasere C.A., Berhow M.T., Messer C.J., Nestler E.J., and Taylor J.R. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. J Neurosci 19 (1999) 4110-4122
    • (1999) J Neurosci , vol.19 , pp. 4110-4122
    • Horger, B.A.1    Iyasere, C.A.2    Berhow, M.T.3    Messer, C.J.4    Nestler, E.J.5    Taylor, J.R.6
  • 74
    • 14944358464 scopus 로고    scopus 로고
    • Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects
    • Hoshaw B.A., Malberg J.E., and Lucki I. Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects. Brain Res 1037 (2005) 204-208
    • (2005) Brain Res , vol.1037 , pp. 204-208
    • Hoshaw, B.A.1    Malberg, J.E.2    Lucki, I.3
  • 75
    • 33749996012 scopus 로고    scopus 로고
    • The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression
    • Hwang J.P., Tsai S.J., Hong C.J., Yang C.H., Lirng J.F., and Yang Y.M. The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression. Neurobiol Aging 27 (2006) 1834-1837
    • (2006) Neurobiol Aging , vol.27 , pp. 1834-1837
    • Hwang, J.P.1    Tsai, S.J.2    Hong, C.J.3    Yang, C.H.4    Lirng, J.F.5    Yang, Y.M.6
  • 76
    • 0025883295 scopus 로고
    • BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF
    • Isackson P.J., Huntsman M.M., Murray K.D., and Gall C.M. BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron 6 (1991) 937-948
    • (1991) Neuron , vol.6 , pp. 937-948
    • Isackson, P.J.1    Huntsman, M.M.2    Murray, K.D.3    Gall, C.M.4
  • 77
    • 0037621531 scopus 로고    scopus 로고
    • Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant
    • Ivy A.S., Rodriguez F.G., Garcia C., Chen M.J., and Russo-Neustadt A.A. Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant. Pharmacol Biochem Behav 75 (2003) 81-88
    • (2003) Pharmacol Biochem Behav , vol.75 , pp. 81-88
    • Ivy, A.S.1    Rodriguez, F.G.2    Garcia, C.3    Chen, M.J.4    Russo-Neustadt, A.A.5
  • 78
    • 4644250763 scopus 로고    scopus 로고
    • The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels
    • Jacobsen J.P., and Mork A. The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. Brain Res 1024 (2004) 183-192
    • (2004) Brain Res , vol.1024 , pp. 183-192
    • Jacobsen, J.P.1    Mork, A.2
  • 79
    • 0028908642 scopus 로고
    • Clinical and neuropsychological characteristics of patients with late-onset schizophrenia
    • Jeste D.V., Harris M.J., Krull A., Kuck J., McAdams L.A., and Heaton R. Clinical and neuropsychological characteristics of patients with late-onset schizophrenia. Am J Psychiatry 152 (1995) 722-730
    • (1995) Am J Psychiatry , vol.152 , pp. 722-730
    • Jeste, D.V.1    Harris, M.J.2    Krull, A.3    Kuck, J.4    McAdams, L.A.5    Heaton, R.6
  • 80
    • 0030967828 scopus 로고    scopus 로고
    • Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation
    • Kang H., Welcher A.A., Shelton D., and Schuman E.M. Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron 19 (1997) 653-664
    • (1997) Neuron , vol.19 , pp. 653-664
    • Kang, H.1    Welcher, A.A.2    Shelton, D.3    Schuman, E.M.4
  • 81
    • 0036202956 scopus 로고    scopus 로고
    • Decreased serum brain-derived neurotrophic factor levels in major depressed patients
    • Karege F., Perret G., Bondolfi G., Schwald M., Bertschy G., and Aubry J.M. Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 109 (2002) 143-148
    • (2002) Psychiatry Res , vol.109 , pp. 143-148
    • Karege, F.1    Perret, G.2    Bondolfi, G.3    Schwald, M.4    Bertschy, G.5    Aubry, J.M.6
  • 82
    • 0037119177 scopus 로고    scopus 로고
    • Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets
    • Karege F., Schwald M., and Cisse M. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 328 (2002) 261-264
    • (2002) Neurosci Lett , vol.328 , pp. 261-264
    • Karege, F.1    Schwald, M.2    Cisse, M.3
  • 83
    • 18144416532 scopus 로고    scopus 로고
    • Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity
    • Karege F., Bondolfi G., Gervasoni N., Schwald M., Aubry J.M., and Bertschy G. Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol Psychiatry 57 (2005) 1068-1072
    • (2005) Biol Psychiatry , vol.57 , pp. 1068-1072
    • Karege, F.1    Bondolfi, G.2    Gervasoni, N.3    Schwald, M.4    Aubry, J.M.5    Bertschy, G.6
  • 84
    • 33645337891 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children
    • Kaufman J., Yang B.Z., Douglas-Palumberi H., Grasso D., Lipschitz D., Houshyar S., et al. Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry 59 (2006) 673-680
    • (2006) Biol Psychiatry , vol.59 , pp. 673-680
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3    Grasso, D.4    Lipschitz, D.5    Houshyar, S.6
  • 85
    • 33746734172 scopus 로고    scopus 로고
    • Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation
    • Khundakar A.A., and Zetterstrom T.S.C. Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation. Brain Res 1106 (2006) 12-20
    • (2006) Brain Res , vol.1106 , pp. 12-20
    • Khundakar, A.A.1    Zetterstrom, T.S.C.2
  • 86
    • 0032402389 scopus 로고    scopus 로고
    • Stress: metaplastic effects in the hippocampus
    • Kim J.J., and Yoon K.S. Stress: metaplastic effects in the hippocampus. Trends Neurosci 21 (1998) 505-509
    • (1998) Trends Neurosci , vol.21 , pp. 505-509
    • Kim, J.J.1    Yoon, K.S.2
  • 87
    • 33745684614 scopus 로고    scopus 로고
    • BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex
    • Kleim J.A., Chan S., Pringle E., Schallert K., Procaccio V., Jimenez R., et al. BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. Nat Neurosci 9 (2006) 735-737
    • (2006) Nat Neurosci , vol.9 , pp. 735-737
    • Kleim, J.A.1    Chan, S.2    Pringle, E.3    Schallert, K.4    Procaccio, V.5    Jimenez, R.6
  • 88
    • 0028343266 scopus 로고
    • Role of neurotrophins in mouse neuronal development
    • Klein R. Role of neurotrophins in mouse neuronal development. FASEB J 8 (1994) 738-744
    • (1994) FASEB J , vol.8 , pp. 738-744
    • Klein, R.1
  • 89
    • 0027491104 scopus 로고
    • Targeted disruption of the TrkB neurotrophin receptor gene results in nervous system lesions and neonatal death
    • Klein R., Smeyne R.J., Wurst W., Long L.K., Auerbach B.A., Joyner A.L., et al. Targeted disruption of the TrkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75 (1993) 113-122
    • (1993) Cell , vol.75 , pp. 113-122
    • Klein, R.1    Smeyne, R.J.2    Wurst, W.3    Long, L.K.4    Auerbach, B.A.5    Joyner, A.L.6
  • 91
    • 0031057457 scopus 로고    scopus 로고
    • Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain
    • Kornblum H.I., Sankar R., Shin D.H., Wasterlain C.G., and Gall C.M. Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. Brain Res Mol Brain Res 44 (1997) 219-228
    • (1997) Brain Res Mol Brain Res , vol.44 , pp. 219-228
    • Kornblum, H.I.1    Sankar, R.2    Shin, D.H.3    Wasterlain, C.G.4    Gall, C.M.5
  • 92
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
    • Korte M., Carroll P., Wolf E., Brem G., Thoenen H., and Bonhoeffer T. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A 92 (1995) 8856-8860
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4    Thoenen, H.5    Bonhoeffer, T.6
  • 93
    • 0032529086 scopus 로고    scopus 로고
    • Effect of chronic restraint stress and tianeptine on growth factors, growth-associated protein-43 and microtubule-associated protein 2 mRNA expression in the rat hippocampus
    • Kuroda Y., and McEwen B.S. Effect of chronic restraint stress and tianeptine on growth factors, growth-associated protein-43 and microtubule-associated protein 2 mRNA expression in the rat hippocampus. Brain Res Mol Brain Res 59 (1998) 35-39
    • (1998) Brain Res Mol Brain Res , vol.59 , pp. 35-39
    • Kuroda, Y.1    McEwen, B.S.2
  • 94
    • 0036113348 scopus 로고    scopus 로고
    • Stress and depression: possible links to neuron death in the hippocampus
    • Lee A.L., Ogle W.O., and Sapolsky R.M. Stress and depression: possible links to neuron death in the hippocampus. Bipolar Disord 4 (2002) 117-128
    • (2002) Bipolar Disord , vol.4 , pp. 117-128
    • Lee, A.L.1    Ogle, W.O.2    Sapolsky, R.M.3
  • 95
    • 33746351511 scopus 로고    scopus 로고
    • Effect of MPEP treatment on brain-derived neurotrophic factor gene expression
    • Legutko B., Szewczyk B., Pomierny-Chamiolo L., Nowak G., and Pilc A. Effect of MPEP treatment on brain-derived neurotrophic factor gene expression. Pharmacol Rep 58 (2006) 427-430
    • (2006) Pharmacol Rep , vol.58 , pp. 427-430
    • Legutko, B.1    Szewczyk, B.2    Pomierny-Chamiolo, L.3    Nowak, G.4    Pilc, A.5
  • 97
    • 33947096866 scopus 로고    scopus 로고
    • Repeated electroconvulsive stimuli have long-lasting effects on hippocampal BDNF and decrease immobility time in the rat forced swim test
    • Li B., Suemaru K., Cui R., and Araki H. Repeated electroconvulsive stimuli have long-lasting effects on hippocampal BDNF and decrease immobility time in the rat forced swim test. Life Sci 80 (2007) 1539-1543
    • (2007) Life Sci , vol.80 , pp. 1539-1543
    • Li, B.1    Suemaru, K.2    Cui, R.3    Araki, H.4
  • 98
    • 0028960484 scopus 로고
    • Spatiotemporal selective effects on brain-derived neurotrophic factor and TrkB messenger RNA in rat hippocampus by electroconvulsive shock
    • Lindefors N., Brodin E., and Metsis M. Spatiotemporal selective effects on brain-derived neurotrophic factor and TrkB messenger RNA in rat hippocampus by electroconvulsive shock. Neuroscience 65 (1995) 661-670
    • (1995) Neuroscience , vol.65 , pp. 661-670
    • Lindefors, N.1    Brodin, E.2    Metsis, M.3
  • 101
    • 1642303117 scopus 로고    scopus 로고
    • Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells
    • Liu Y., Encinas M., Comella J.X., Aldea M., and Gallego C. Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells. Mol Cell Biol 24 (2004) 2662-2672
    • (2004) Mol Cell Biol , vol.24 , pp. 2662-2672
    • Liu, Y.1    Encinas, M.2    Comella, J.X.3    Aldea, M.4    Gallego, C.5
  • 102
    • 0033592920 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
    • Lyons W.E., Mamounas L.A., Ricaurte G.A., Coppola V., Reid S.W., Bora S.H., et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci U S A 96 (1999) 15239-15244
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 15239-15244
    • Lyons, W.E.1    Mamounas, L.A.2    Ricaurte, G.A.3    Coppola, V.4    Reid, S.W.5    Bora, S.H.6
  • 103
    • 0034801530 scopus 로고    scopus 로고
    • Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression
    • MacQueen G.M., Ramakrishnan K., Croll S.D., Siuciak J.A., Yu G., Young L.T., et al. Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behav Neurosci 115 (2001) 1145-1153
    • (2001) Behav Neurosci , vol.115 , pp. 1145-1153
    • MacQueen, G.M.1    Ramakrishnan, K.2    Croll, S.D.3    Siuciak, J.A.4    Yu, G.5    Young, L.T.6
  • 104
    • 0025720531 scopus 로고
    • Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations
    • Maisonpierre P.C., Le Beau M.M., Espinosa R., Ip I.I.I., Belluscio N.Y., de la Monte L., et al. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics 10 (1991) 558-568
    • (1991) Genomics , vol.10 , pp. 558-568
    • Maisonpierre, P.C.1    Le Beau, M.M.2    Espinosa, R.3    Ip, I.I.I.4    Belluscio, N.Y.5    de la Monte, L.6
  • 105
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg J.E., Eisch A.J., Nestler E.J., and Duman R.S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20 (2000) 9104-9110
    • (2000) J Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 106
    • 0029584365 scopus 로고
    • Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
    • Mamounas L.A., Blue M.E., Siuciak J.A., and Altar C.A. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J Neurosci 15 (1995) 7929-7939
    • (1995) J Neurosci , vol.15 , pp. 7929-7939
    • Mamounas, L.A.1    Blue, M.E.2    Siuciak, J.A.3    Altar, C.A.4
  • 107
    • 0034651078 scopus 로고    scopus 로고
    • BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain
    • Mamounas L.A., Altar C.A., Blue M.E., Kaplan D.R., Tessarollo L., and Lyons W.E. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. J Neurosci 20 (2000) 771-782
    • (2000) J Neurosci , vol.20 , pp. 771-782
    • Mamounas, L.A.1    Altar, C.A.2    Blue, M.E.3    Kaplan, D.R.4    Tessarollo, L.5    Lyons, W.E.6
  • 108
    • 0035034203 scopus 로고    scopus 로고
    • The cellular neurobiology of depression
    • Manji H.K., Drevets W.C., and Charney D.S. The cellular neurobiology of depression. Nat Med 7 (2001) 541-547
    • (2001) Nat Med , vol.7 , pp. 541-547
    • Manji, H.K.1    Drevets, W.C.2    Charney, D.S.3
  • 109
    • 34247518130 scopus 로고    scopus 로고
    • Increased plasma concentration of brain-derived neurotrophic factor with electroconvulsive therapy: a pilot study in patients with major depression
    • Marano C.M., Phatak P., Vemulapalli U.R., Sasan A., Nalbandyan M.R., Ramanujam S., et al. Increased plasma concentration of brain-derived neurotrophic factor with electroconvulsive therapy: a pilot study in patients with major depression. J Clin Psychiatry 68 (2007) 512-517
    • (2007) J Clin Psychiatry , vol.68 , pp. 512-517
    • Marano, C.M.1    Phatak, P.2    Vemulapalli, U.R.3    Sasan, A.4    Nalbandyan, M.R.5    Ramanujam, S.6
  • 110
    • 0028265181 scopus 로고
    • Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine
    • Martin-Iverson M.T., Todd K.G., and Altar C.A. Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine. J Neurosci 14 (1994) 1262-1270
    • (1994) J Neurosci , vol.14 , pp. 1262-1270
    • Martin-Iverson, M.T.1    Todd, K.G.2    Altar, C.A.3
  • 111
    • 27744584919 scopus 로고    scopus 로고
    • Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment
    • Martinez-Turrillas R., Del R.J., and Frechilla D. Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. Neuropharmacology 49 (2005) 1178-1188
    • (2005) Neuropharmacology , vol.49 , pp. 1178-1188
    • Martinez-Turrillas, R.1    Del, R.J.2    Frechilla, D.3
  • 112
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers C., and Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3 (2006) e442
    • (2006) PLoS Med , vol.3
    • Mathers, C.1    Loncar, D.2
  • 113
    • 23944468510 scopus 로고    scopus 로고
    • Energy intake, meal frequency, and health: a neurobiological perspective
    • Mattson M.P. Energy intake, meal frequency, and health: a neurobiological perspective. Annu Rev Nutr 25 (2005) 237-260
    • (2005) Annu Rev Nutr , vol.25 , pp. 237-260
    • Mattson, M.P.1
  • 114
    • 4544328810 scopus 로고    scopus 로고
    • BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders
    • Mattson M.P., Maudsley S., and Martin B. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends Neurosci 27 (2004) 589-594
    • (2004) Trends Neurosci , vol.27 , pp. 589-594
    • Mattson, M.P.1    Maudsley, S.2    Martin, B.3
  • 115
    • 0032895804 scopus 로고    scopus 로고
    • Stress and the aging hippocampus
    • McEwen B.S. Stress and the aging hippocampus. Front Neuroendocrinol 20 (1999) 49-70
    • (1999) Front Neuroendocrinol , vol.20 , pp. 49-70
    • McEwen, B.S.1
  • 116
    • 0037072518 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration
    • Meredith G.E., Callen S., and Scheuer D.A. Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration. Brain Res 949 (2002) 218-227
    • (2002) Brain Res , vol.949 , pp. 218-227
    • Meredith, G.E.1    Callen, S.2    Scheuer, D.A.3
  • 117
    • 0026025820 scopus 로고
    • TrkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors
    • Middlemas D.S., Lindberg R.A., and Hunter T. TrkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. Mol Cell Biol 11 (1991) 143-153
    • (1991) Mol Cell Biol , vol.11 , pp. 143-153
    • Middlemas, D.S.1    Lindberg, R.A.2    Hunter, T.3
  • 118
    • 0033213270 scopus 로고    scopus 로고
    • Essential role for TrkB receptors in hippocampus-mediated learning
    • Minichiello L., Korte M., Wolfer D., Kuhn R., Unsicker K., Cestari V., et al. Essential role for TrkB receptors in hippocampus-mediated learning. Neuron 24 (1999) 401-414
    • (1999) Neuron , vol.24 , pp. 401-414
    • Minichiello, L.1    Korte, M.2    Wolfer, D.3    Kuhn, R.4    Unsicker, K.5    Cestari, V.6
  • 119
    • 0036913698 scopus 로고    scopus 로고
    • Regulation of cAMP phosphodiesterase mRNAs expression in rat brain by acute and chronic fluoxetine treatment. An in situ hybridization study
    • Miro X., Perez-Torres S., Artigas F., Puigdomenech P., Palacios J.M., and Mengod G. Regulation of cAMP phosphodiesterase mRNAs expression in rat brain by acute and chronic fluoxetine treatment. An in situ hybridization study. Neuropharmacology 43 (2002) 1148-1157
    • (2002) Neuropharmacology , vol.43 , pp. 1148-1157
    • Miro, X.1    Perez-Torres, S.2    Artigas, F.3    Puigdomenech, P.4    Palacios, J.M.5    Mengod, G.6
  • 120
    • 0033597983 scopus 로고    scopus 로고
    • Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease
    • Mogi M., Togari A., Kondo T., Mizuno Y., Komure O., Kuno S., et al. Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci Lett 270 (1999) 45-48
    • (1999) Neurosci Lett , vol.270 , pp. 45-48
    • Mogi, M.1    Togari, A.2    Kondo, T.3    Mizuno, Y.4    Komure, O.5    Kuno, S.6
  • 121
    • 1442316352 scopus 로고    scopus 로고
    • Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray
    • Molteni R., Ying Z., and Gomez-Pinilla F. Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray. Eur J Neurosci 16 (2002) 1107-1116
    • (2002) Eur J Neurosci , vol.16 , pp. 1107-1116
    • Molteni, R.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 122
    • 0036135090 scopus 로고    scopus 로고
    • Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms
    • Momose Y., Murata M., Kobayashi K., Tachikawa M., Nakabayashi Y., Kanazawa I., et al. Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms. Ann Neurol 51 (2002) 133-136
    • (2002) Ann Neurol , vol.51 , pp. 133-136
    • Momose, Y.1    Murata, M.2    Kobayashi, K.3    Tachikawa, M.4    Nakabayashi, Y.5    Kanazawa, I.6
  • 124
    • 4944248818 scopus 로고    scopus 로고
    • Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity
    • Monteleone P., Tortorella A., Martiadis V., Serritella C., Fuschino A., and Maj M. Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity. Psychosom Med 66 (2004) 744-748
    • (2004) Psychosom Med , vol.66 , pp. 744-748
    • Monteleone, P.1    Tortorella, A.2    Martiadis, V.3    Serritella, C.4    Fuschino, A.5    Maj, M.6
  • 126
    • 33748791795 scopus 로고    scopus 로고
    • Cyclic AMP response element binding protein and brain-derived neurotrophic factor: molecules that modulate our mood?
    • Nair A., and Vaidya V.A. Cyclic AMP response element binding protein and brain-derived neurotrophic factor: molecules that modulate our mood?. J Biosci 31 (2006) 423-434
    • (2006) J Biosci , vol.31 , pp. 423-434
    • Nair, A.1    Vaidya, V.A.2
  • 127
    • 34447095464 scopus 로고    scopus 로고
    • Stressor-Specific Regulation of Distinct Brain-Derived Neurotrophic Factor Transcripts and Cyclic AMP Response Element-Binding Protein Expression in the Postnatal and Adult Rat Hippocampus
    • Nair A., Vadodaria K.C., Banerjee S.B., Benekareddy M., Dias B.G., Duman R.S., et al. Stressor-Specific Regulation of Distinct Brain-Derived Neurotrophic Factor Transcripts and Cyclic AMP Response Element-Binding Protein Expression in the Postnatal and Adult Rat Hippocampus. Neuropsychopharmacology (2006)
    • (2006) Neuropsychopharmacology
    • Nair, A.1    Vadodaria, K.C.2    Banerjee, S.B.3    Benekareddy, M.4    Dias, B.G.5    Duman, R.S.6
  • 128
    • 18144435678 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice
    • Nakagawa T., Tsuchida A., Itakura Y., Nonomura T., Ono M., Hirota F., et al. Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice. Diabetes 49 (2000) 436-444
    • (2000) Diabetes , vol.49 , pp. 436-444
    • Nakagawa, T.1    Tsuchida, A.2    Itakura, Y.3    Nonomura, T.4    Ono, M.5    Hirota, F.6
  • 129
    • 0142042981 scopus 로고    scopus 로고
    • Decreased levels of serum brain-derived neurotrophic factor in female patients with eating disorders
    • Nakazato M., Hashimoto K., Shimizu E., Kumakiri C., Koizumi H., Okamura N., et al. Decreased levels of serum brain-derived neurotrophic factor in female patients with eating disorders. Biol Psychiatry 54 (2003) 485-490
    • (2003) Biol Psychiatry , vol.54 , pp. 485-490
    • Nakazato, M.1    Hashimoto, K.2    Shimizu, E.3    Kumakiri, C.4    Koizumi, H.5    Okamura, N.6
  • 130
    • 0010330438 scopus 로고    scopus 로고
    • Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
    • Neeper S.A., Gomez-Pinilla F., Choi J., and Cotman C.W. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res 726 (1996) 49-56
    • (1996) Brain Res , vol.726 , pp. 49-56
    • Neeper, S.A.1    Gomez-Pinilla, F.2    Choi, J.3    Cotman, C.W.4
  • 131
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler E.J., and Carlezon Jr. W.A. The mesolimbic dopamine reward circuit in depression. Biol Psychiatry 59 (2006) 1151-1159
    • (2006) Biol Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon Jr., W.A.2
  • 133
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study
    • Neves-Pereira M., Mundo E., Muglia P., King N., Macciardi F., and Kennedy J.L. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet 71 (2002) 651-655
    • (2002) Am J Hum Genet , vol.71 , pp. 651-655
    • Neves-Pereira, M.1    Mundo, E.2    Muglia, P.3    King, N.4    Macciardi, F.5    Kennedy, J.L.6
  • 135
    • 0028815653 scopus 로고
    • Regulation of BDNF and TrkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M., Morinobu S., and Duman R.S. Regulation of BDNF and TrkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 15 (1995) 7539-7547
    • (1995) J Neurosci , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 136
    • 0029992189 scopus 로고    scopus 로고
    • Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus
    • Nibuya M., Nestler E.J., and Duman R.S. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci 16 (1996) 2365-2372
    • (1996) J Neurosci , vol.16 , pp. 2365-2372
    • Nibuya, M.1    Nestler, E.J.2    Duman, R.S.3
  • 137
    • 0032513036 scopus 로고    scopus 로고
    • Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish
    • Nilsson A.S., Fainzilber M., Falck P., and Ibanez C.F. Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish. FEBS Lett 424 (1998) 285-290
    • (1998) FEBS Lett , vol.424 , pp. 285-290
    • Nilsson, A.S.1    Fainzilber, M.2    Falck, P.3    Ibanez, C.F.4
  • 138
    • 0033566332 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor prevents neuronal cell death induced by corticosterone
    • Nitta A., Ohmiya M., Sometani A., Itoh M., Nomoto H., Furukawa Y., et al. Brain-derived neurotrophic factor prevents neuronal cell death induced by corticosterone. J Neurosci Res 57 (1999) 227-235
    • (1999) J Neurosci Res , vol.57 , pp. 227-235
    • Nitta, A.1    Ohmiya, M.2    Sometani, A.3    Itoh, M.4    Nomoto, H.5    Furukawa, Y.6
  • 139
    • 0037492595 scopus 로고    scopus 로고
    • Dynamic changes in AP-1 transcription factor DNA binding activity in rat brain following administration of antidepressant amitriptyline and brain-derived neurotrophic factor
    • Okamoto H., Shino Y., Hashimoto K., Kumakiri C., Shimizu E., Shirasawa H., et al. Dynamic changes in AP-1 transcription factor DNA binding activity in rat brain following administration of antidepressant amitriptyline and brain-derived neurotrophic factor. Neuropharmacology 45 (2003) 251-259
    • (2003) Neuropharmacology , vol.45 , pp. 251-259
    • Okamoto, H.1    Shino, Y.2    Hashimoto, K.3    Kumakiri, C.4    Shimizu, E.5    Shirasawa, H.6
  • 141
    • 0032582853 scopus 로고    scopus 로고
    • Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus
    • Oliff H.S., Berchtold N.C., Isackson P., and Cotman C.W. Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Mol Brain Res 61 (1998) 147-153
    • (1998) Mol Brain Res , vol.61 , pp. 147-153
    • Oliff, H.S.1    Berchtold, N.C.2    Isackson, P.3    Cotman, C.W.4
  • 142
    • 0033220002 scopus 로고    scopus 로고
    • Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test
    • Page M.E., Detke M.J., Dalvi A., Kirby L.G., and Lucki I. Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test. Psychopharmacology (Berl) 147 (1999) 162-167
    • (1999) Psychopharmacology (Berl) , vol.147 , pp. 162-167
    • Page, M.E.1    Detke, M.J.2    Dalvi, A.3    Kirby, L.G.4    Lucki, I.5
  • 143
    • 0032404127 scopus 로고    scopus 로고
    • Transport of brain-derived neurotrophic factor across the blood-brain barrier
    • Pan W., Banks W.A., Fasold M.B., Bluth J., and Kastin A.J. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37 (1998) 1553-1561
    • (1998) Neuropharmacology , vol.37 , pp. 1553-1561
    • Pan, W.1    Banks, W.A.2    Fasold, M.B.3    Bluth, J.4    Kastin, A.J.5
  • 144
    • 5644251587 scopus 로고    scopus 로고
    • Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity
    • Pang P.T., Teng H.K., Zaitsev E., Woo N.T., Sakata K., Zhen S., et al. Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 306 (2004) 487-491
    • (2004) Science , vol.306 , pp. 487-491
    • Pang, P.T.1    Teng, H.K.2    Zaitsev, E.3    Woo, N.T.4    Sakata, K.5    Zhen, S.6
  • 145
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • Patterson S.L., Abel T., Deuel T.A., Martin K.C., Rose J.C., and Kandel E.R. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16 (1996) 1137-1145
    • (1996) Neuron , vol.16 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 146
    • 0035449745 scopus 로고    scopus 로고
    • Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus
    • Pencea V., Bingaman K.D., Wiegand S.J., and Luskin M.B. Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus. J Neurosci 21 (2001) 6706-6717
    • (2001) J Neurosci , vol.21 , pp. 6706-6717
    • Pencea, V.1    Bingaman, K.D.2    Wiegand, S.J.3    Luskin, M.B.4
  • 147
    • 8544249878 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology
    • Pezawas L., Verchinski B.A., Mattay V.S., Callicott J.H., Kolachana B.S., Straub R.E., et al. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J Neurosci 24 (2004) 10099-10102
    • (2004) J Neurosci , vol.24 , pp. 10099-10102
    • Pezawas, L.1    Verchinski, B.A.2    Mattay, V.S.3    Callicott, J.H.4    Kolachana, B.S.5    Straub, R.E.6
  • 148
    • 0029803039 scopus 로고    scopus 로고
    • Timing of neuronal death in trkA, TrkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling
    • Pinon L.G., Minichiello L., Klein R., and Davies A.M. Timing of neuronal death in trkA, TrkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling. Development 122 (1996) 3255-3261
    • (1996) Development , vol.122 , pp. 3255-3261
    • Pinon, L.G.1    Minichiello, L.2    Klein, R.3    Davies, A.M.4
  • 149
    • 0037344826 scopus 로고    scopus 로고
    • Psychological and fitness changes associated with exercise participation among women with breast cancer
    • Pinto B.M., Clark M.M., Maruyama N.C., and Feder S.I. Psychological and fitness changes associated with exercise participation among women with breast cancer. Psychooncology 12 (2003) 118-126
    • (2003) Psychooncology , vol.12 , pp. 118-126
    • Pinto, B.M.1    Clark, M.M.2    Maruyama, N.C.3    Feder, S.I.4
  • 150
    • 0029928170 scopus 로고    scopus 로고
    • Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF
    • Poduslo J.F., and Curran G.L. Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Res 36 (1996) 280-286
    • (1996) Brain Res Mol Brain Res , vol.36 , pp. 280-286
    • Poduslo, J.F.1    Curran, G.L.2
  • 151
    • 0017618768 scopus 로고
    • Depression: a new animal model sensitive to antidepressant treatments
    • Porsolt R.D., Le Pichon M., and Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 266 (1977) 730-732
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 152
    • 0018268297 scopus 로고
    • Behavioural despair in rats: a new model sensitive to antidepressant treatments
    • Porsolt R.D., Anton G., Blavet N., and Jalfre M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol 47 (1978) 379-391
    • (1978) Eur J Pharmacol , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 153
    • 0026906520 scopus 로고
    • Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF)
    • Proschel M., Saunders A., Roses A.D., and Muller C.R. Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF). Hum Mol Genet 1 (1992) 353
    • (1992) Hum Mol Genet , vol.1 , pp. 353
    • Proschel, M.1    Saunders, A.2    Roses, A.D.3    Muller, C.R.4
  • 154
    • 0030062891 scopus 로고    scopus 로고
    • Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay
    • Radka S.F., Holst P.A., Fritsche M., and Altar C.A. Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay. Brain Res 709 (1996) 122-301
    • (1996) Brain Res , vol.709 , pp. 122-301
    • Radka, S.F.1    Holst, P.A.2    Fritsche, M.3    Altar, C.A.4
  • 155
    • 0036298493 scopus 로고    scopus 로고
    • Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock
    • Rasmusson A.M., Shi L., and Duman R. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology 27 (2002) 133-142
    • (2002) Neuropsychopharmacology , vol.27 , pp. 133-142
    • Rasmusson, A.M.1    Shi, L.2    Duman, R.3
  • 156
    • 0036024263 scopus 로고    scopus 로고
    • Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus
    • Roceri M., Hendriks W., Racagni G., Ellenbroek B.A., and Riva M.A. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Mol Psychiatry 7 (2002) 609-616
    • (2002) Mol Psychiatry , vol.7 , pp. 609-616
    • Roceri, M.1    Hendriks, W.2    Racagni, G.3    Ellenbroek, B.A.4    Riva, M.A.5
  • 157
    • 0032863708 scopus 로고    scopus 로고
    • Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression
    • Russo-Neustadt A., Beard R.C., and Cotman C.W. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology 21 (1999) 679-682
    • (1999) Neuropsychopharmacology , vol.21 , pp. 679-682
    • Russo-Neustadt, A.1    Beard, R.C.2    Cotman, C.W.3
  • 158
    • 0034619534 scopus 로고    scopus 로고
    • Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus
    • Russo-Neustadt A.A., Beard R.C., Huang Y.M., and Cotman C.W. Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus. Neuroscience 101 (2000) 305-312
    • (2000) Neuroscience , vol.101 , pp. 305-312
    • Russo-Neustadt, A.A.1    Beard, R.C.2    Huang, Y.M.3    Cotman, C.W.4
  • 159
    • 0035826517 scopus 로고    scopus 로고
    • Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model
    • Russo-Neustadt A., Ha T., Ramirez R., and Kesslak J.P. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behav Brain Res 120 (2001) 87-95
    • (2001) Behav Brain Res , vol.120 , pp. 87-95
    • Russo-Neustadt, A.1    Ha, T.2    Ramirez, R.3    Kesslak, J.P.4
  • 160
    • 9644294196 scopus 로고    scopus 로고
    • Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise
    • Russo-Neustadt A.A., Alejandre H., Garcia C., Ivy A.S., and Chen M.J. Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise. Neuropsychopharmacology 29 (2004) 2189-2199
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2189-2199
    • Russo-Neustadt, A.A.1    Alejandre, H.2    Garcia, C.3    Ivy, A.S.4    Chen, M.J.5
  • 161
    • 0037218768 scopus 로고    scopus 로고
    • Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects
    • Saarelainen T., Hendolin P., Lucas G., Koponen E., Sairanen M., MacDonald E., et al. Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J Neurosci 23 (2003) 349-357
    • (2003) J Neurosci , vol.23 , pp. 349-357
    • Saarelainen, T.1    Hendolin, P.2    Lucas, G.3    Koponen, E.4    Sairanen, M.5    MacDonald, E.6
  • 162
    • 13944257674 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    • Sairanen M., Lucas G., Ernfors P., Castren M., and Castren E. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J Neurosci 25 (2005) 1089-1094
    • (2005) J Neurosci , vol.25 , pp. 1089-1094
    • Sairanen, M.1    Lucas, G.2    Ernfors, P.3    Castren, M.4    Castren, E.5
  • 163
    • 33751527786 scopus 로고    scopus 로고
    • Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat
    • Sairanen M., O'Leary O.F., Knuuttila J.E., and Castren E. Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat. Neuroscience 144 (2007) 368-374
    • (2007) Neuroscience , vol.144 , pp. 368-374
    • Sairanen, M.1    O'Leary, O.F.2    Knuuttila, J.E.3    Castren, E.4
  • 164
    • 0023580093 scopus 로고
    • Voluntary wheel running exercise and monoamine levels in brain, heart and adrenal glands of aging mice
    • Samorajski T., Rolsten C., Przykorska A., and Davis C.M. Voluntary wheel running exercise and monoamine levels in brain, heart and adrenal glands of aging mice. Exp Gerontol 22 (1987) 421-431
    • (1987) Exp Gerontol , vol.22 , pp. 421-431
    • Samorajski, T.1    Rolsten, C.2    Przykorska, A.3    Davis, C.M.4
  • 165
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L., Saxe M., Gross C., Surget A., Battaglia F., Dulawa S., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301 (2003) 805-809
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1    Saxe, M.2    Gross, C.3    Surget, A.4    Battaglia, F.5    Dulawa, S.6
  • 166
    • 0033800486 scopus 로고    scopus 로고
    • Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
    • Sapolsky R.M. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry 57 (2000) 925-935
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 925-935
    • Sapolsky, R.M.1
  • 167
    • 0030750084 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene and schizophrenia in Japanese subjects
    • Sasaki T., Dai X.Y., Kuwata S., Fukuda R., Kunugi H., Hattori M., et al. Brain-derived neurotrophic factor gene and schizophrenia in Japanese subjects. Am J Med Genet 74 (1997) 443-444
    • (1997) Am J Med Genet , vol.74 , pp. 443-444
    • Sasaki, T.1    Dai, X.Y.2    Kuwata, S.3    Fukuda, R.4    Kunugi, H.5    Hattori, M.6
  • 168
    • 0034536215 scopus 로고    scopus 로고
    • The neurotrophin hypothesis for synaptic plasticity
    • Schinder A.F., and Poo M. The neurotrophin hypothesis for synaptic plasticity. Trends Neurosci 23 (2000) 639-645
    • (2000) Trends Neurosci , vol.23 , pp. 639-645
    • Schinder, A.F.1    Poo, M.2
  • 169
    • 0029747240 scopus 로고    scopus 로고
    • Comparative study of brain-derived neurotrophic factor messenger RNA and protein at the cellular level suggests multiple roles in hippocampus, striatum and cortex
    • Schmidt-Kastner R., Wetmore C., and Olson L. Comparative study of brain-derived neurotrophic factor messenger RNA and protein at the cellular level suggests multiple roles in hippocampus, striatum and cortex. Neuroscience 74 (1996) 161-183
    • (1996) Neuroscience , vol.74 , pp. 161-183
    • Schmidt-Kastner, R.1    Wetmore, C.2    Olson, L.3
  • 171
    • 0033564043 scopus 로고    scopus 로고
    • Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
    • Sheline Y.I., Sanghavi M., Mintun M.A., and Gado M.H. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J Neurosci 19 (1999) 5034-5043
    • (1999) J Neurosci , vol.19 , pp. 5034-5043
    • Sheline, Y.I.1    Sanghavi, M.2    Mintun, M.A.3    Gado, M.H.4
  • 172
    • 0041880262 scopus 로고    scopus 로고
    • Untreated depression and hippocampal volume loss
    • Sheline Y.I., Gado M.H., and Kraemer H.C. Untreated depression and hippocampal volume loss. Am J Psychiatry 160 (2003) 1516-1518
    • (2003) Am J Psychiatry , vol.160 , pp. 1516-1518
    • Sheline, Y.I.1    Gado, M.H.2    Kraemer, H.C.3
  • 173
    • 0038771149 scopus 로고    scopus 로고
    • Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants
    • Shimizu E., Hashimoto K., Okamura N., Koike K., Komatsu N., Kumakiri C., et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 54 (2003) 70-75
    • (2003) Biol Psychiatry , vol.54 , pp. 70-75
    • Shimizu, E.1    Hashimoto, K.2    Okamura, N.3    Koike, K.4    Komatsu, N.5    Kumakiri, C.6
  • 174
    • 1842486891 scopus 로고    scopus 로고
    • Ethnic difference of the BDNF 196G/A (val66met) polymorphism frequencies: the possibility to explain ethnic mental traits
    • Shimizu E., Hashimoto K., and Iyo M. Ethnic difference of the BDNF 196G/A (val66met) polymorphism frequencies: the possibility to explain ethnic mental traits. Am J Med Genet B Neuropsychiatr Genet 126 (2004) 122-123
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.126 , pp. 122-123
    • Shimizu, E.1    Hashimoto, K.2    Iyo, M.3
  • 175
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y., Chen A.C., Nakagawa S., Russell D.S., and Duman R.S. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 22 (2002) 3251-3261
    • (2002) J Neurosci , vol.22 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 176
    • 0034890632 scopus 로고    scopus 로고
    • The efficacy of exercise as a long-term antidepressant in elderly subjects: a randomized, controlled trial
    • Singh N.A., Clements K.M., and Singh M.A. The efficacy of exercise as a long-term antidepressant in elderly subjects: a randomized, controlled trial. J Gerontol A Biol Sci Med Sci 56 (2001) M497-M504
    • (2001) J Gerontol A Biol Sci Med Sci , vol.56
    • Singh, N.A.1    Clements, K.M.2    Singh, M.A.3
  • 177
    • 0029925352 scopus 로고    scopus 로고
    • BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration
    • Siuciak J.A., Boylan C., Fritsche M., Altar C.A., and Lindsay R.M. BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration. Brain Res 710 (1996) 11-20
    • (1996) Brain Res , vol.710 , pp. 11-20
    • Siuciak, J.A.1    Boylan, C.2    Fritsche, M.3    Altar, C.A.4    Lindsay, R.M.5
  • 180
    • 0028970281 scopus 로고
    • Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus
    • Smith M.A., Makino S., Kvetnansky R., and Post R.M. Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J Neurosci 15 (1995) 1768-1777
    • (1995) J Neurosci , vol.15 , pp. 1768-1777
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3    Post, R.M.4
  • 181
    • 0030788275 scopus 로고    scopus 로고
    • Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers
    • Smith M.A., Zhang L.X., Lyons W.E., and Mamounas L.A. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport 8 (1997) 1829-1834
    • (1997) Neuroreport , vol.8 , pp. 1829-1834
    • Smith, M.A.1    Zhang, L.X.2    Lyons, W.E.3    Mamounas, L.A.4
  • 182
    • 0025827738 scopus 로고
    • The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the TrkB tyrosine kinase receptor
    • Soppet D., Escandon E., Maragos J., Middlemas D.S., Reid S.W., Blair J., et al. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the TrkB tyrosine kinase receptor. Cell 65 (1991) 895-903
    • (1991) Cell , vol.65 , pp. 895-903
    • Soppet, D.1    Escandon, E.2    Maragos, J.3    Middlemas, D.S.4    Reid, S.W.5    Blair, J.6
  • 183
    • 0025731382 scopus 로고
    • TrkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
    • Squinto S.P., Stitt T.N., Aldrich T.H., Davis S., Bianco S.M., Radziejewski C., et al. TrkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell 65 (1991) 885-893
    • (1991) Cell , vol.65 , pp. 885-893
    • Squinto, S.P.1    Stitt, T.N.2    Aldrich, T.H.3    Davis, S.4    Bianco, S.M.5    Radziejewski, C.6
  • 184
    • 27744498029 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample
    • Strauss J., Barr C.L., George C.J., Devlin B., Vetro A., Kiss E., et al. Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample. Mol Psychiatry 10 (2005) 861-867
    • (2005) Mol Psychiatry , vol.10 , pp. 861-867
    • Strauss, J.1    Barr, C.L.2    George, C.J.3    Devlin, B.4    Vetro, A.5    Kiss, E.6
  • 185
    • 21844458922 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation
    • Szeszko P.R., Lipsky R., Mentschel C., Robinson D., Gunduz-Bruce H., Sevy S., et al. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Mol Psychiatry 10 (2005) 631-636
    • (2005) Mol Psychiatry , vol.10 , pp. 631-636
    • Szeszko, P.R.1    Lipsky, R.2    Mentschel, C.3    Robinson, D.4    Gunduz-Bruce, H.5    Sevy, S.6
  • 186
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • Thoenen H. Neurotrophins and neuronal plasticity. Science 270 (1995) 593-598
    • (1995) Science , vol.270 , pp. 593-598
    • Thoenen, H.1
  • 188
    • 26944467560 scopus 로고    scopus 로고
    • Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats
    • Torregrossa M.M., Folk J.E., Rice K.C., Watson S.J., and Woods J.H. Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats. Psychopharmacology (Berl) 183 (2005) 31-40
    • (2005) Psychopharmacology (Berl) , vol.183 , pp. 31-40
    • Torregrossa, M.M.1    Folk, J.E.2    Rice, K.C.3    Watson, S.J.4    Woods, J.H.5
  • 189
    • 33845336449 scopus 로고    scopus 로고
    • Increased central brain-derived neurotrophic factor activity could be a risk factor for substance abuse: Implications for treatment
    • Tsai S.J. Increased central brain-derived neurotrophic factor activity could be a risk factor for substance abuse: Implications for treatment. Med Hypotheses 68 (2007) 410-414
    • (2007) Med Hypotheses , vol.68 , pp. 410-414
    • Tsai, S.J.1
  • 192
    • 0035875958 scopus 로고    scopus 로고
    • BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses
    • Tyler W.J., and Pozzo-Miller L.D. BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J Neurosci 21 (2001) 4249-4258
    • (2001) J Neurosci , vol.21 , pp. 4249-4258
    • Tyler, W.J.1    Pozzo-Miller, L.D.2
  • 193
    • 0034962407 scopus 로고    scopus 로고
    • Depresssion-emerging insights from neurobiology
    • Vaidya V.A., and Duman R.S. Depresssion-emerging insights from neurobiology. Br Med Bull 57 (2001) 61-79
    • (2001) Br Med Bull , vol.57 , pp. 61-79
    • Vaidya, V.A.1    Duman, R.S.2
  • 194
    • 0030611192 scopus 로고    scopus 로고
    • 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex
    • Vaidya V.A., Marek G.J., Aghajanian G.K., and Duman R.S. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. J Neurosci 17 (1997) 2785-2795
    • (1997) J Neurosci , vol.17 , pp. 2785-2795
    • Vaidya, V.A.1    Marek, G.J.2    Aghajanian, G.K.3    Duman, R.S.4
  • 195
    • 0004665855 scopus 로고    scopus 로고
    • Hippocampal mossy fiber sprouting induced by chronic electroconvulsive seizures
    • Vaidya V.A., Siuciak J.A., Du F., and Duman R.S. Hippocampal mossy fiber sprouting induced by chronic electroconvulsive seizures. Neuroscience 89 (1999) 157-166
    • (1999) Neuroscience , vol.89 , pp. 157-166
    • Vaidya, V.A.1    Siuciak, J.A.2    Du, F.3    Duman, R.S.4
  • 196
    • 0028800803 scopus 로고
    • The NeurotroDhins BDNF, NT-3 and NT-4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal Neurons In Vitro
    • Ventimiglia R., Mather P.E., Jones B.E., and Lindsay R.M. The NeurotroDhins BDNF, NT-3 and NT-4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal Neurons In Vitro. Eur J Neurosci 7 (1995) 213-222
    • (1995) Eur J Neurosci , vol.7 , pp. 213-222
    • Ventimiglia, R.1    Mather, P.E.2    Jones, B.E.3    Lindsay, R.M.4
  • 198
  • 199
    • 0043267729 scopus 로고    scopus 로고
    • ECT of major depressed patients in relation to biological and clinical variables: a brief overview
    • Wahlund B., and von Rosen D. ECT of major depressed patients in relation to biological and clinical variables: a brief overview. Neuropsychopharmacology 28 Suppl 1 (2003) S21-S26
    • (2003) Neuropsychopharmacology , vol.28 , Issue.SUPPL. 1
    • Wahlund, B.1    von Rosen, D.2
  • 200
    • 0026544569 scopus 로고
    • Physical activity and stroke in British middle aged men
    • Wannamethee G., and Shaper A.G. Physical activity and stroke in British middle aged men. BMJ 304 (1992) 597-601
    • (1992) BMJ , vol.304 , pp. 597-601
    • Wannamethee, G.1    Shaper, A.G.2
  • 201
    • 0033573270 scopus 로고    scopus 로고
    • Heritability of BDNF alleles and their effect on brain morphology in schizophrenia
    • Wassink T.H., Nelson J.J., Crowe R.R., and Andreasen N.C. Heritability of BDNF alleles and their effect on brain morphology in schizophrenia. Am J Med Genet 88 (1999) 724-728
    • (1999) Am J Med Genet , vol.88 , pp. 724-728
    • Wassink, T.H.1    Nelson, J.J.2    Crowe, R.R.3    Andreasen, N.C.4
  • 202
    • 34247576658 scopus 로고    scopus 로고
    • A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression
    • Wilkie M.J., Smith D., Reid I.C., Day R.K., Matthews K., Wolf C.R., et al. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression. Pharmacogenet Genom 17 (2007) 207-215
    • (2007) Pharmacogenet Genom , vol.17 , pp. 207-215
    • Wilkie, M.J.1    Smith, D.2    Reid, I.C.3    Day, R.K.4    Matthews, K.5    Wolf, C.R.6
  • 203
    • 0035348160 scopus 로고    scopus 로고
    • Research and treatment approaches to depression
    • Wong M.L., and Licinio J. Research and treatment approaches to depression. Nat Rev Neurosci 2 (2001) 343-351
    • (2001) Nat Rev Neurosci , vol.2 , pp. 343-351
    • Wong, M.L.1    Licinio, J.2
  • 204
    • 0037209045 scopus 로고    scopus 로고
    • Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus
    • Xu H., Steven R.J., and Li X.M. Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology 28 (2003) 53-62
    • (2003) Neuropsychopharmacology , vol.28 , pp. 53-62
    • Xu, H.1    Steven, R.J.2    Li, X.M.3
  • 205
    • 0025514278 scopus 로고
    • Human platelets contain brain-derived neurotrophic factor
    • Yamamoto H., and Gurney M.E. Human platelets contain brain-derived neurotrophic factor. J Neurosci 10 (1990) 3469-3478
    • (1990) J Neurosci , vol.10 , pp. 3469-3478
    • Yamamoto, H.1    Gurney, M.E.2
  • 206
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J., and Yankner B.A. Apoptosis in the nervous system. Nature 407 (2000) 802-809
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 207
    • 0032104158 scopus 로고    scopus 로고
    • Repeated electroconvulsive shock extends the duration of enhanced gene expression for BDNF in rat brain compared with a single administration
    • Zetterstrom T.S., Pei Q., and Grahame-Smith D.G. Repeated electroconvulsive shock extends the duration of enhanced gene expression for BDNF in rat brain compared with a single administration. Brain Res Mol Brain Res 57 (1998) 106-110
    • (1998) Brain Res Mol Brain Res , vol.57 , pp. 106-110
    • Zetterstrom, T.S.1    Pei, Q.2    Grahame-Smith, D.G.3
  • 209
    • 0031856527 scopus 로고    scopus 로고
    • Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb
    • Zigova T., Pencea V., Wiegand S.J., and Luskin M.B. Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb. Mol Cell Neurosci 11 (1998) 234-245
    • (1998) Mol Cell Neurosci , vol.11 , pp. 234-245
    • Zigova, T.1    Pencea, V.2    Wiegand, S.J.3    Luskin, M.B.4


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