Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain

Molecular Brain Research

Volumn 44, Issue 2, 1997, Pages 219-228

  Kornblum, Harley I ^a,b   Sankar, Raman ^a   Shin, Don H ^a   Wasterlain, Claude G ^a,b   Gall, Christine M ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain; Brain derived neurotrophic factor; Development; Electroencephalogram; Epilepsy; Hybridization; In situ; Kainic acid; Neurotrophin; Pilocarpine; Seizure

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DIAZEPAM; KAINIC ACID; LITHIUM; MESSENGER RNA; PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; GENE INDUCTION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; LIMBIC CORTEX; NEOCORTEX; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; PYRIFORM CORTEX; RAT; SEIZURE;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; KAINIC ACID; LITHIUM; PILOCARPINE; RATS; RATS, WISTAR; RNA, MESSENGER; SEIZURES;

ANIMALIA; MAMMALIA;

EID: 0031057457     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00224-0     Document Type: Article

References (15)

1. Alderson, R.F., Alterman A.L., Barde, Y.A. and Lindsay, R.M., Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron, 5 (1990) 297-306.
2. Babb, T.L., Kupfer, W.R., Pretorius, J.K., Crandall, P.H. and Levesque, M.F., Synaptic reorganization by mossy fibers in human epileptic fascia dentata. Neuroscience, 42 (1991) 351-363.
3. Bahn, S., Volk, B. and Wisden, W., Kainate receptor gene expression in the developing rat brain. J. Neurosci., 14 (1994) 5525-5547.
4. Barde, Y.A., Davies, A.M., Johnson, J.E., Lindsay, R.M. and Thoenen, H., Brain derived neurotrophic factor. Prog. Brain Res., 71 (1987) 185-189.
5. Berzaghi, M.J., Cooper, E., Castren, E., Zafra, M., Sofroniew, H., Thoenen, H. and Lindholm, D., Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampus. J. Neurosci., 13 (1993) 3818-3826.
6. Cavalheiro, E.A., Leite, J.P., Bortolotto, Z.A., Turski, W.A., Ikonomidou, C. and Turski, L., Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia, 32 (1991) 778-782.
7. Cavalheiro, E.A., Silva, D.E., Turski, W.A., Calderazzo, F.L., Bortolotto, Z.A. and Turski, L., The susceptibility of rats to pilocarpine-induced seizures is age-dependent. Brain Res., 465 (1987) 43-58.
8. Chao, M.V., Neurotrophin receptors: A window into neuronal differentiation. Neuron, 9 (1992) 583-593.
9. Cheng, B. and Mattson, M.P., NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain Res., 640 (1994) 56-67.
10. Dugich, D.M., Tocco, G., Lapchak, P.A., Pasinetti, G.M., Najm, I., Baudry, M. and Hefti, F., Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid. Neuroscience, 47 (1992) 303-315.
11. Dugich, D.M., Tocco, G., Willoughby, D.A., Najm, I., Pasinetti, G., Thompson, R.F., Baudry, M., Lapchak, P.A. and Hefti, F., BDNF mRNA expression in the developing rat brain following kainic acid-induced seizure activity. Neuron, (1992) 8 1127-1138.
12. Ebendal, T., Function and evolution in the NGF family and its receptors. J. Neurosci. Res., 32 (1992) 461-470.
13. Gall, C.M., Regulation of brain neurotrophin expression by physiological activity. Trends Pharmacol. Sci., 13 (1992) 401-403.
14. Gall, C.M., Seizure-induced changes in neurotrophin expression: implications for epilepsy. Exp. Neurol., 124 (1993) 150-166.
15. Gall, C.M. and Isackson, P.J., Limbic seizures increase neuronal production of messenger RNA for nerve growth factor. Science, 245 (1989) 758-761.