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Volumn 15, Issue 17, 1999, Pages 1519-1527

Effect of long-term infection with nef-defective attenuated hiv type 1 on CD4+ and CD8+ T lymphocytes: Increased CD45RO+CD4+ T lymphocytes and limited activation of CD8+ T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; NEF PROTEIN; PADGEM PROTEIN; VIRUS RNA;

EID: 0033589778     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922299309801     Document Type: Article
Times cited : (27)

References (52)
  • 4
    • 0030769854 scopus 로고    scopus 로고
    • Novel campaign to test live HIV vaccine
    • Cohen J: Novel campaign to test live HIV vaccine. Science 1997; 277:1035.
    • (1997) Science , vol.277 , pp. 1035
    • Cohen, J.1
  • 5
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
    • Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, and Desrosiers RC: Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 1992;258:1938-1941.
    • (1992) Science , vol.258 , pp. 1938-1941
    • Daniel, M.D.1    Kirchhoff, F.2    Czajak, S.C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 6
    • 0032888972 scopus 로고    scopus 로고
    • Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1
    • Dyer WB, Ogg GS, Demoitie M-A, Jin X, Geczy AF, Rowland-Jones SL, McMichael AJ, Nixon DF, and Sullivan JS: Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1. J Virol 1999;73:436-443.
    • (1999) J Virol , vol.73 , pp. 436-443
    • Dyer, W.B.1    Ogg, G.S.2    Demoitie, M.-A.3    Jin, X.4    Geczy, A.F.5    Rowland-Jones, S.L.6    McMichael, A.J.7    Nixon, D.F.8    Sullivan, J.S.9
  • 8
    • 0030785330 scopus 로고    scopus 로고
    • Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection
    • Dyer WB, Geczy AF, Kent SJ, McIntyre LB, Blasdall SA, Learmont J, and Sullivan JS: Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection. AIDS 1997;11:1565-1574.
    • (1997) AIDS , vol.11 , pp. 1565-1574
    • Dyer, W.B.1    Geczy, A.F.2    Kent, S.J.3    McIntyre, L.B.4    Blasdall, S.A.5    Learmont, J.6    Sullivan, J.S.7
  • 10
    • 9844236467 scopus 로고    scopus 로고
    • Increased losses of CD4+CD45RA+ cells in late stages of HIV infection is related to increased risk of death: Evidence from a cohort of 347 HIV-infected individuals
    • Ullum H, Cozzi Lepri A, Victor J, Skinhoj P, Phillips AN, and Klarlund Pedersen B: Increased losses of CD4+CD45RA+ cells in late stages of HIV infection is related to increased risk of death: Evidence from a cohort of 347 HIV-infected individuals. AIDS 1997;11:1479-1485.
    • (1997) AIDS , vol.11 , pp. 1479-1485
    • Ullum, H.1    Cozzi Lepri, A.2    Victor, J.3    Skinhoj, P.4    Phillips, A.N.5    Klarlund Pedersen, B.6
  • 11
    • 0029016192 scopus 로고
    • Effects of primary HIV-1 infection on subsets of CD4+ and CD8+ T lymphocytes
    • Zaunders J, Carr A, McNally L, Penny R, and Cooper D: Effects of primary HIV-1 infection on subsets of CD4+ and CD8+ T lymphocytes. AIDS 1995;9:561-566.
    • (1995) AIDS , vol.9 , pp. 561-566
    • Zaunders, J.1    Carr, A.2    McNally, L.3    Penny, R.4    Cooper, D.5
  • 12
    • 0030052964 scopus 로고    scopus 로고
    • Alterations in the immune response of human immunodeficiency virus (HIV)-infected subjects treated with an HIV-specific protease inhibitor, ritonavir
    • Kelleher AD, Carr A, Zaunders J, and Cooper DA: Alterations in the immune response of human immunodeficiency virus (HIV)-infected subjects treated with an HIV-specific protease inhibitor, ritonavir. J Infect Dis 1996;173:321-329.
    • (1996) J Infect Dis , vol.173 , pp. 321-329
    • Kelleher, A.D.1    Carr, A.2    Zaunders, J.3    Cooper, D.A.4
  • 13
  • 15
    • 0344026065 scopus 로고    scopus 로고
    • Low relative frequencies of CD26+ CD4+ cells in long-term nonprogressing human immunodeficiency virus type 1-infected subjects
    • Broström C, Sönnerborg A, Lindback S, and Gaines H: Low relative frequencies of CD26+ CD4+ cells in long-term nonprogressing human immunodeficiency virus type 1-infected subjects. Clin Diag Lab Immunol 1998;5:662-666.
    • (1998) Clin Diag Lab Immunol , vol.5 , pp. 662-666
    • Broström, C.1    Sönnerborg, A.2    Lindback, S.3    Gaines, H.4
  • 19
    • 0030048020 scopus 로고    scopus 로고
    • Predominant involvement of CD8+CD28-lymphocytes in human immunodeficiency virus-specific cytotoxic activity
    • Fiorentino S, Dalod M, Olive D, Guillet J-G, and Gomard E: Predominant involvement of CD8+CD28-lymphocytes in human immunodeficiency virus-specific cytotoxic activity. J Virol 1996; 70:2022-2026.
    • (1996) J Virol , vol.70 , pp. 2022-2026
    • Fiorentino, S.1    Dalod, M.2    Olive, D.3    Guillet, J.-G.4    Gomard, E.5
  • 20
    • 0029983022 scopus 로고    scopus 로고
    • Delayed virus-specific CD8+ cytotoxic T lymphocyte activity in an HIV-infected individual with high CD4+ cells counts: Correlation with various parameters of disease progression
    • Dalod M, Fiorentino S, Delamare C, Rouzioux C, Sicard D, Guillet J-G, and Gomard E: Delayed virus-specific CD8+ cytotoxic T lymphocyte activity in an HIV-infected individual with high CD4+ cells counts: Correlation with various parameters of disease progression. AIDS Res Hum Retroviruses 1996;12:497-506.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 497-506
    • Dalod, M.1    Fiorentino, S.2    Delamare, C.3    Rouzioux, C.4    Sicard, D.5    Guillet, J.-G.6    Gomard, E.7
  • 21
    • 0027965585 scopus 로고
    • CD8+ lymphocyte activation at human immunodeficency virus type 1 seroconversion: Development of HLA-DR+CD38-CD8+ cells is associated with subsequent stable CD4+ cell levels
    • Giorgi JV, Ho N-H, Hirji K, Chou C-C, Hultin LE, O'Rourke S, Park L, Margolick JB, Ferbas J, Phair JP, and the Multicentre AIDS Cohort Study Group: CD8+ lymphocyte activation at human immunodeficency virus type 1 seroconversion: Development of HLA-DR+CD38-CD8+ cells is associated with subsequent stable CD4+ cell levels. J Infect Dis 1994;170:775-781.
    • (1994) J Infect Dis , vol.170 , pp. 775-781
    • Giorgi, J.V.1    Ho, N.-H.2    Hirji, K.3    Chou, C.-C.4    Hultin, L.E.5    O'Rourke, S.6    Park, L.7    Margolick, J.B.8    Ferbas, J.9    Phair, J.P.10
  • 26
    • 0030017679 scopus 로고    scopus 로고
    • CD8+ lymphocyte phenotype and cytokine production in long-term non-progressor and in progressor patients with HIV-1 infection
    • Zanussi S, Simonelli C, D'Andrea M, Caffau C, Clerici M, Tirelli U, and De Paoli P: CD8+ lymphocyte phenotype and cytokine production in long-term non-progressor and in progressor patients with HIV-1 infection. Clin Exp Immunol 1996;105:220-224.
    • (1996) Clin Exp Immunol , vol.105 , pp. 220-224
    • Zanussi, S.1    Simonelli, C.2    D'Andrea, M.3    Caffau, C.4    Clerici, M.5    Tirelli, U.6    De Paoli, P.7
  • 27
    • 0032211145 scopus 로고    scopus 로고
    • Virological and immunological features of long-term human immunodeficiency virus-infected individuals who have remained asymptomatic compared with those who have progressed to acquired immunodeficiency syndrome
    • Barker E, Mackewicz CE, Reyes-Teran G, Sato A, Stranford SA, Fujimura SH, Christopherson C, Chang S-Y, and Levy JA: Virological and immunological features of long-term human immunodeficiency virus-infected individuals who have remained asymptomatic compared with those who have progressed to acquired immunodeficiency syndrome. Blood 1998;92:3105-3114.
    • (1998) Blood , vol.92 , pp. 3105-3114
    • Barker, E.1    Mackewicz, C.E.2    Reyes-Teran, G.3    Sato, A.4    Stranford, S.A.5    Fujimura, S.H.6    Christopherson, C.7    Chang, S.-Y.8    Levy, J.A.9
  • 28
    • 0028837645 scopus 로고
    • Reference intervals for human peripheral blood lymphocyte subpopulations from "healthy" young and aged subjects
    • Stulnig T, Maczek C, Bock G, Majdic O, and Wick G: Reference intervals for human peripheral blood lymphocyte subpopulations from "healthy" young and aged subjects. Int Arch Allergy Immunol 1995;108:205-210.
    • (1995) Int Arch Allergy Immunol , vol.108 , pp. 205-210
    • Stulnig, T.1    Maczek, C.2    Bock, G.3    Majdic, O.4    Wick, G.5
  • 29
    • 0030744134 scopus 로고    scopus 로고
    • Role of phosphatases in lymphocyte activation
    • Neel BG: Role of phosphatases in lymphocyte activation. Curr Opin Immunol 1997;9:405-420.
    • (1997) Curr Opin Immunol , vol.9 , pp. 405-420
    • Neel, B.G.1
  • 30
    • 0023893710 scopus 로고    scopus 로고
    • Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells
    • Akbar AN, Terry L, Timms A, Beverley PCL, and Janossy G: Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 1998;140:2171-2178.
    • (1998) J Immunol , vol.140 , pp. 2171-2178
    • Akbar, A.N.1    Terry, L.2    Timms, A.3    Beverley, P.C.L.4    Janossy, G.5
  • 31
    • 0025086509 scopus 로고
    • Interconversion of CD45R subsets of CD4 T cells in vivo
    • Bell EB and Sparshott SM: Interconversion of CD45R subsets of CD4 T cells in vivo. Nature (London) 1990;348:163-166.
    • (1990) Nature (London) , vol.348 , pp. 163-166
    • Bell, E.B.1    Sparshott, S.M.2
  • 32
    • 0030832222 scopus 로고    scopus 로고
    • Immunological memory
    • Sprent J: Immunological memory. Curr Opin Immunol 1997;9: 371-379.
    • (1997) Curr Opin Immunol , vol.9 , pp. 371-379
    • Sprent, J.1
  • 33
    • 0023934515 scopus 로고
    • Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2 and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production
    • Sanders ME, Makgoba MW, Sharrow SO, Stephany D, Springer TA, Young HA, and Shaw S: Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2 and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production. J Immunol 1988;140:1401-1407.
    • (1988) J Immunol , vol.140 , pp. 1401-1407
    • Sanders, M.E.1    Makgoba, M.W.2    Sharrow, S.O.3    Stephany, D.4    Springer, T.A.5    Young, H.A.6    Shaw, S.7
  • 34
    • 0024210023 scopus 로고
    • Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: Implications for differential CD45 expression in T cell memory formation
    • Merkenschlager M, Terry L, Edwards R, and Beverley PCL: Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: Implications for differential CD45 expression in T cell memory formation. Eur J Immunol 1988;18:1653-1661.
    • (1988) Eur J Immunol , vol.18 , pp. 1653-1661
    • Merkenschlager, M.1    Terry, L.2    Edwards, R.3    Beverley, P.C.L.4
  • 35
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki67
    • Gerdes J, Lemke H, Baisch H, Wacker H-H, Schwab U, and Stein H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki67. J Immunol 1984;133:1710-1715.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.-H.4    Schwab, U.5    Stein, H.6
  • 38
    • 0025160079 scopus 로고
    • Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals
    • Schnittman SM, Lane HC, Greenhouse J, Justment JS, Baseler M, and Fauci AS: Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc Natl Acad Sci USA 1990;87:6058-6062.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6058-6062
    • Schnittman, S.M.1    Lane, H.C.2    Greenhouse, J.3    Justment, J.S.4    Baseler, M.5    Fauci, A.S.6
  • 39
    • 0031010762 scopus 로고    scopus 로고
    • Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI
    • Chun T-W, Chadwick K, Margolick J, and Siliciano RF: Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI. J Virol 1997;71:4436-4444.
    • (1997) J Virol , vol.71 , pp. 4436-4444
    • Chun, T.-W.1    Chadwick, K.2    Margolick, J.3    Siliciano, R.F.4
  • 41
    • 0030968495 scopus 로고    scopus 로고
    • Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro
    • Spina CA, Prince HE, and Richman DD: Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro. J Clin Invest 1997;99:1774-1785.
    • (1997) J Clin Invest , vol.99 , pp. 1774-1785
    • Spina, C.A.1    Prince, H.E.2    Richman, D.D.3
  • 42
    • 0031016699 scopus 로고    scopus 로고
    • Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells
    • Woods TC, Roberts BD, Butera ST, and Folks TM: Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells. Blood 1997;89:1635-1641.
    • (1997) Blood , vol.89 , pp. 1635-1641
    • Woods, T.C.1    Roberts, B.D.2    Butera, S.T.3    Folks, T.M.4
  • 43
    • 0028081082 scopus 로고
    • Distinct alterations in the distribution of CD45RO+ T-cell subsets in HIV-2 compared with HIV-1 infection
    • Jaleco AC, Covas MJ, Pinto LA, and Victorino RMM: Distinct alterations in the distribution of CD45RO+ T-cell subsets in HIV-2 compared with HIV-1 infection. AIDS 1994;8:1663-1668.
    • (1994) AIDS , vol.8 , pp. 1663-1668
    • Jaleco, A.C.1    Covas, M.J.2    Pinto, L.A.3    Victorino, R.M.M.4
  • 44
    • 0001199710 scopus 로고
    • Reactivity of workshop T-cell section mAb with circulating CD4+ and CD8+ T cells in HIV disease and following in vitro activation
    • (Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, and Todd RF, eds.), Oxford University Press, Oxford
    • Giorgi JV, Boumsell L, and Autran B: Reactivity of workshop T-cell section mAb with circulating CD4+ and CD8+ T cells in HIV disease and following in vitro activation. In: Leukocyte Typing V (Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, and Todd RF, eds.), Vol. 1. Oxford University Press, Oxford, 1995, pp. 446-461.
    • (1995) Leukocyte Typing V , vol.1 , pp. 446-461
    • Giorgi, J.V.1    Boumsell, L.2    Autran, B.3
  • 46
    • 0029811734 scopus 로고    scopus 로고
    • Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells
    • Cardin RD, Brooks JW, Sarawar SR, and Doherty PC: Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells. J Exp Med 1996;184:863-871.
    • (1996) J Exp Med , vol.184 , pp. 863-871
    • Cardin, R.D.1    Brooks, J.W.2    Sarawar, S.R.3    Doherty, P.C.4
  • 48
    • 0030045992 scopus 로고    scopus 로고
    • Correlation of CD8 lymphocyte activation with cellular viremia and plasma HIV RNA levels in asymptomatic patients infected by human immunodeficiency virus type 1
    • Bouscarat F, Levacher-Clergeot M, Dazza M-C, Strauss KW, Girard P-M, Ruggeri C, and Sinet M: Correlation of CD8 lymphocyte activation with cellular viremia and plasma HIV RNA levels in asymptomatic patients infected by human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1996;12:17-24.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 17-24
    • Bouscarat, F.1    Levacher-Clergeot, M.2    Dazza, M.-C.3    Strauss, K.W.4    Girard, P.-M.5    Ruggeri, C.6    Sinet, M.7
  • 49
    • 0033503076 scopus 로고    scopus 로고
    • Potent antiretroviral therapy of primary HIV-1 infection: Partial normalization of T lymphocyte subsets and subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia
    • Zaunders JJ, Cunningham PH, Kelleher AD, Kaufman GR, Jaramillo AB, Wright R, Smith D, Grey P, Vizzard J, Carr A, and Cooper DA: Potent antiretroviral therapy of primary HIV-1 infection: Partial normalization of T lymphocyte subsets and subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia. J Infect Dis 1999;180:320-329.
    • (1999) J Infect Dis , vol.180 , pp. 320-329
    • Zaunders, J.J.1    Cunningham, P.H.2    Kelleher, A.D.3    Kaufman, G.R.4    Jaramillo, A.B.5    Wright, R.6    Smith, D.7    Grey, P.8    Vizzard, J.9    Carr, A.10    Cooper, D.A.11
  • 50
    • 0031958156 scopus 로고    scopus 로고
    • Major expansions of select CD8+ subsets in acute Epstein-Barr virus infection: Comparison with chronic human immunodeficiency virus disease
    • Lynne JE, Schmid I, Matud JL, Hirji K, Buessow S, Shlian DM, and Giorgi JV: Major expansions of select CD8+ subsets in acute Epstein-Barr virus infection: Comparison with chronic human immunodeficiency virus disease. J Infect Dis 1998;177:1083-1087.
    • (1998) J Infect Dis , vol.177 , pp. 1083-1087
    • Lynne, J.E.1    Schmid, I.2    Matud, J.L.3    Hirji, K.4    Buessow, S.5    Shlian, D.M.6    Giorgi, J.V.7
  • 51
    • 0032581692 scopus 로고    scopus 로고
    • Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy
    • Bouscarat F, Levacher M, Landman R, Muffat JM, Girard PM, Saimot AG, Brun VF, and Sinet M: Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy. AIDS 1998;12:1267-1273.
    • (1998) AIDS , vol.12 , pp. 1267-1273
    • Bouscarat, F.1    Levacher, M.2    Landman, R.3    Muffat, J.M.4    Girard, P.M.5    Saimot, A.G.6    Brun, V.F.7    Sinet, M.8
  • 52
    • 0033590405 scopus 로고    scopus 로고
    • Declining CD4 T cell counts in a person infected with nef-deleted HIV-1
    • Greenough TC, Sullivan JL, and Desrosiers RC: Declining CD4 T cell counts in a person infected with nef-deleted HIV-1. N Engl J Med 1999;340:236-237.
    • (1999) N Engl J Med , vol.340 , pp. 236-237
    • Greenough, T.C.1    Sullivan, J.L.2    Desrosiers, R.C.3


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