Structure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR Degradation

Structure

Volumn 15, Issue 11, 2007, Pages 1493-1504

  Bullock, Alex N ^a   Rodriguez, Maria C ^b   Debreczeni, Judit É ^a   Songyang, Zhou ^b   Knapp, Stefan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

PROTEINS; SIGNALING

Indexed keywords

CYTOKINE; ELONGIN BC; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH HORMONE RECEPTOR; JANUS KINASE 2; PEPTIDE; PROTEIN SH2; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 2; SUPPRESSOR OF CYTOKINE SIGNALING 3; SUPPRESSOR OF CYTOKINE SIGNALING 4; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; ISOLEUCINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOTYROSINE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE ALIGNMENT; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION FACTORS;

EID: 35748984946     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2007.09.016     Document Type: Article

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