Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 20, 2006, Pages 7637-7642

  Bullock, Alex N ^a   Debreczeni, Judit É ^a   Edwards, Aled M ^b   Sundström, Michael ^a   Knapp, Stefan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cytokine signaling; Growth hormone receptor

Indexed keywords

CULLIN; ELONGIN BC; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; PROTEIN SH2; S PHASE KINASE ASSOCIATED PROTEIN 2; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 2; SUPPRESSOR OF CYTOKINE SIGNALING 3; SUPPRESSOR OF CYTOKINE SIGNALING 4; SUPPRESSOR OF CYTOKINE SIGNALING 5; SUPPRESSOR OF CYTOKINE SIGNALING 7; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME SUBSTRATE COMPLEX; KNOCKOUT MOUSE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES;

EID: 33646733227     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0601638103     Document Type: Article

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