The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation

FASEB Journal

Volumn 21, Issue 11, 2007, Pages 2849-2862

  Omerovic, Jasminka ^a   Santangelo, Laura ^a   Puggioni, Eleonora Maria Rosaria ^a   Marrocco, Jordan ^a   Dall'Armi, Claudia ^b   Palumbo, Camilla ^b   Belleudi, Francesca ^a   Di Marcotullio, Lucia ^a   Frati, Luigi ^a,c   Torrisi, Maria Rosaria ^a,d,e   Cesareni, Gianni ^b   Gulino, Alberto ^a,c   Alimandi, Maurizio ^a,f  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c IRCCS NEUROMED   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e SAN GALLICANO DERMATOLOGICAL INSTITUTE   (Italy)

^f REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Negative regulators; Nuclear translocation; Ubiquitin ligase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 4; POLYUBIQUITIN; PROTEIN AIP4; PROTEIN ITCH; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; LYSOSOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; RECEPTOR BINDING; UBIQUITINATION;

BLOTTING, WESTERN; BRAIN; ENDOSOMES; FLUORESCENT ANTIBODY TECHNIQUE; GENE LIBRARY; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; KIDNEY; PEPTIDE LIBRARY; PROTEIN INTERACTION MAPPING; PROTEIN TRANSPORT; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRESSOR PROTEINS; SUBCELLULAR FRACTIONS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 34548501531     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-7925com     Document Type: Article

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