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Volumn 9, Issue 11, 2007, Pages 1899-1909

Role of redox reactions in the vascular phenotype of hyperhomocysteinemic animals

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 35448965209     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2007.1806     Document Type: Review
Times cited : (23)

References (106)
  • 1
    • 0036713354 scopus 로고    scopus 로고
    • Plasma homocysteine levels and atherosclerosis in Japan: Epidemiological study by use of carotid ultrasonography
    • Adachi H, Hirai Y, Fujiura Y, Matsuoka H, Satoh A, and Imaizumi T. Plasma homocysteine levels and atherosclerosis in Japan: epidemiological study by use of carotid ultrasonography. Stroke 33: 2177-2181, 2002.
    • (2002) Stroke , vol.33 , pp. 2177-2181
    • Adachi, H.1    Hirai, Y.2    Fujiura, Y.3    Matsuoka, H.4    Satoh, A.5    Imaizumi, T.6
  • 2
    • 0034489653 scopus 로고    scopus 로고
    • The glutathione peroxidases
    • Arthur JR. The glutathione peroxidases. Cell Mol Life Sci 57: 1825-1835, 2000.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1825-1835
    • Arthur, J.R.1
  • 3
    • 0036141841 scopus 로고    scopus 로고
    • Xanthine oxidase-derived reactive oxygen species convert flow-induced arteriolar dilation to constriction in hyperhomocysteinemia: Possible role of peroxynitrite
    • Bagi Z, Ungvari Z, and Koller A. Xanthine oxidase-derived reactive oxygen species convert flow-induced arteriolar dilation to constriction in hyperhomocysteinemia: possible role of peroxynitrite. Arterioscler Thromb Vas Biol 22: 28-33, 2002.
    • (2002) Arterioscler Thromb Vas Biol , vol.22 , pp. 28-33
    • Bagi, Z.1    Ungvari, Z.2    Koller, A.3
  • 4
    • 0035140872 scopus 로고    scopus 로고
    • Evidence for inducible nitric-oxide synthase expression and activity in vascular smooth muscle of streptozotocin-diabetic rats
    • Bardell AL and MacLeod KM. Evidence for inducible nitric-oxide synthase expression and activity in vascular smooth muscle of streptozotocin-diabetic rats. J Pharmacol Exp Ther 296: 252-259, 2001.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 252-259
    • Bardell, A.L.1    MacLeod, K.M.2
  • 5
    • 33745939390 scopus 로고    scopus 로고
    • Hypertrophy of cerebral arterioles in mice deficient in expression of the gene for CuZn superoxide dismutase
    • Baumbach GL, Didion SP, and Faraci FM. Hypertrophy of cerebral arterioles in mice deficient in expression of the gene for CuZn superoxide dismutase. Stroke 37: 1850-1855, 2006.
    • (2006) Stroke , vol.37 , pp. 1850-1855
    • Baumbach, G.L.1    Didion, S.P.2    Faraci, F.M.3
  • 6
    • 0037112386 scopus 로고    scopus 로고
    • Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice
    • Baumbach GL, Sigmund CD, Bottiglieri T, and Lentz SR. Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice. Circ Res 91: 931-937, 2002.
    • (2002) Circ Res , vol.91 , pp. 931-937
    • Baumbach, G.L.1    Sigmund, C.D.2    Bottiglieri, T.3    Lentz, S.R.4
  • 7
    • 6344241908 scopus 로고    scopus 로고
    • Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase
    • Baumbach GL, Sigmund CD, and Faraci FM. Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase. Circ Res 95: 822-829, 2004.
    • (2004) Circ Res , vol.95 , pp. 822-829
    • Baumbach, G.L.1    Sigmund, C.D.2    Faraci, F.M.3
  • 8
    • 17744363661 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, a cardiac metabolic disease: Role of nitric oxide and the p22phox subunit of NADPH oxidase
    • Becker JS, Adler A, Schneeberger A, Huang H, Wang Z, Walsh E, Koller A, and Hintze TH. Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase. Circulation 111: 2112-2118, 2005.
    • (2005) Circulation , vol.111 , pp. 2112-2118
    • Becker, J.S.1    Adler, A.2    Schneeberger, A.3    Huang, H.4    Wang, Z.5    Walsh, E.6    Koller, A.7    Hintze, T.H.8
  • 9
    • 0034730108 scopus 로고    scopus 로고
    • Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits
    • Behr-Roussel D, Rupin A, Simonet S, Bonhomme E, Coumailleau S, Cordi A, Serkiz B, Fabiani JN, and Verbeuren TJ. Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits. Circulation 102: 1033-1038, 2000.
    • (2000) Circulation , vol.102 , pp. 1033-1038
    • Behr-Roussel, D.1    Rupin, A.2    Simonet, S.3    Bonhomme, E.4    Coumailleau, S.5    Cordi, A.6    Serkiz, B.7    Fabiani, J.N.8    Verbeuren, T.J.9
  • 10
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H and Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87: 840-844, 2000.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 11
    • 13444262357 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: Regulator of endothelial nitric oxide synthase in vascular disease
    • Channon KM. Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med 14: 323-327, 2004.
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 323-327
    • Channon, K.M.1
  • 12
    • 0036146184 scopus 로고    scopus 로고
    • Intraperitoneal infusion of homocysteine increases intimal hyperplasia in balloon-injured rat carotid arteries
    • Chen C, Surowiec SM, Morsy AH, and Ma M. Intraperitoneal infusion of homocysteine increases intimal hyperplasia in balloon-injured rat carotid arteries. Atherosclerosis 160: 103-114, 2002.
    • (2002) Atherosclerosis , vol.160 , pp. 103-114
    • Chen, C.1    Surowiec, S.M.2    Morsy, A.H.3    Ma, M.4
  • 14
    • 21744448674 scopus 로고    scopus 로고
    • Homocysteine-lowering trials for prevention of heart disease and stroke
    • Clarke R. Homocysteine-lowering trials for prevention of heart disease and stroke. Semin Vasc Med 5: 215-222, 2005.
    • (2005) Semin Vasc Med , vol.5 , pp. 215-222
    • Clarke, R.1
  • 15
    • 0036363436 scopus 로고    scopus 로고
    • Neointimal hyperplasia in balloon-injured rat carotid arteries: The influence of hyperhomocysteinemia
    • Cook JW, Malinow MR, Moneta GL, Taylor LM, and Orloff SL. Neointimal hyperplasia in balloon-injured rat carotid arteries: the influence of hyperhomocysteinemia. J Vasc Surg 35: 158-165, 2002.
    • (2002) J Vasc Surg , vol.35 , pp. 158-165
    • Cook, J.W.1    Malinow, M.R.2    Moneta, G.L.3    Taylor, L.M.4    Orloff, S.L.5
  • 20
    • 33749329880 scopus 로고    scopus 로고
    • Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia
    • Dayal S, Wilson KM, Leo L, Arning E, Bottiglieri T, and Lentz SR. Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia. Blood 108: 2237-2243, 2006.
    • (2006) Blood , vol.108 , pp. 2237-2243
    • Dayal, S.1    Wilson, K.M.2    Leo, L.3    Arning, E.4    Bottiglieri, T.5    Lentz, S.R.6
  • 21
    • 0032007564 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle
    • De Keulenaer GW, Alexander RW, Ushio-Fukai M, Ishizaka N, and Griendling KK. Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle. Biochem J 329: 653-657, 1998.
    • (1998) Biochem J , vol.329 , pp. 653-657
    • De Keulenaer, G.W.1    Alexander, R.W.2    Ushio-Fukai, M.3    Ishizaka, N.4    Griendling, K.K.5
  • 22
    • 2442669073 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia
    • De Vriese AS, Blom HJ, Heil SG, Mortier S, Kluijtmans LA, Van de Voorde J, and Lameire NH. Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia. Circulation 109: 2331-2336, 2004.
    • (2004) Circulation , vol.109 , pp. 2331-2336
    • De Vriese, A.S.1    Blom, H.J.2    Heil, S.G.3    Mortier, S.4    Kluijtmans, L.A.5    Van de Voorde, J.6    Lameire, N.H.7
  • 24
    • 1642312607 scopus 로고    scopus 로고
    • Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice
    • Devlin AM, Arning E, Bottiglieri T, Faraci FM, Rozen R, and Lentz SR. Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice. Blood 103: 2624-2629, 2004.
    • (2004) Blood , vol.103 , pp. 2624-2629
    • Devlin, A.M.1    Arning, E.2    Bottiglieri, T.3    Faraci, F.M.4    Rozen, R.5    Lentz, S.R.6
  • 25
    • 21844477565 scopus 로고    scopus 로고
    • Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia
    • Devlin AM, Bottiglieri T, Domann FE, and Lentz SR. Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia. J Biol Chem 280: 25506-25511, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 25506-25511
    • Devlin, A.M.1    Bottiglieri, T.2    Domann, F.E.3    Lentz, S.R.4
  • 27
    • 0036140785 scopus 로고    scopus 로고
    • Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering
    • Doshi SN, McDowell IF, Moat SJ, Payne N, Durrant HJ, Lewis MJ, and Goodfellow J. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation 105: 22-26, 2002.
    • (2002) Circulation , vol.105 , pp. 22-26
    • Doshi, S.N.1    McDowell, I.F.2    Moat, S.J.3    Payne, N.4    Durrant, H.J.5    Lewis, M.J.6    Goodfellow, J.7
  • 28
    • 0037592128 scopus 로고    scopus 로고
    • Hyperhomocysteinemia due to folate deficiency is thrombogenic in rats
    • Ebbesen LS, Christiansen K, and Ingerslev J. Hyperhomocysteinemia due to folate deficiency is thrombogenic in rats. J Nutr 133: 2250-2255, 2003.
    • (2003) J Nutr , vol.133 , pp. 2250-2255
    • Ebbesen, L.S.1    Christiansen, K.2    Ingerslev, J.3
  • 30
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: A multifaceted disorder (The Wiggers Award Lecture)
    • Feletou M and Vanhoutte PM. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol 291: H985-H1002, 2006.
    • (2006) Am J Physiol , vol.291
    • Feletou, M.1    Vanhoutte, P.M.2
  • 31
    • 21744462251 scopus 로고    scopus 로고
    • Homocysteine: Overview of biochemistry, molecular biology, and role in disease processes
    • Fowler B. Homocysteine: overview of biochemistry, molecular biology, and role in disease processes. Semin Vasc Med 5: 77-86, 2005.
    • (2005) Semin Vasc Med , vol.5 , pp. 77-86
    • Fowler, B.1
  • 32
    • 0037123435 scopus 로고    scopus 로고
    • PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells
    • Frey RS, Rahman A, Kefer JC, Minshall RD, and Malik AB. PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells. Circ Res 90: 1012-1019, 2002.
    • (2002) Circ Res , vol.90 , pp. 1012-1019
    • Frey, R.S.1    Rahman, A.2    Kefer, J.C.3    Minshall, R.D.4    Malik, A.B.5
  • 33
    • 0027103736 scopus 로고
    • Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity: A potential rapid mechanism for modulation of coagulation
    • Glaser CB, Morser J, Clarke JH, Blasko E, McLean K, Kuhn I, Chang RJ, Lin JH, Vilander L, Andrews WH, and Light DR. Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity: a potential rapid mechanism for modulation of coagulation. J Clin Invest 90: 2565-2573, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 2565-2573
    • Glaser, C.B.1    Morser, J.2    Clarke, J.H.3    Blasko, E.4    McLean, K.5    Kuhn, I.6    Chang, R.J.7    Lin, J.H.8    Vilander, L.9    Andrews, W.H.10    Light, D.R.11
  • 34
    • 0027288252 scopus 로고
    • Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor
    • Hajjar KA. Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J Clin Iinvest 91: 2873-2879, 1993.
    • (1993) J Clin Iinvest , vol.91 , pp. 2873-2879
    • Hajjar, K.A.1
  • 35
    • 18144404121 scopus 로고    scopus 로고
    • Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation
    • Handy DE, Zhang Y, and Loscalzo J. Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation. J Biol Chem 280: 15518-15525, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 15518-15525
    • Handy, D.E.1    Zhang, Y.2    Loscalzo, J.3
  • 36
    • 0017197285 scopus 로고
    • Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response in its genesis
    • Harker LA, Ross R, Slichter SJ, and Scott CR. Homocystine-induced arteriosclerosis: the role of endothelial cell injury and platelet response in its genesis. J Clin Invest 58: 731-741, 1976.
    • (1976) J Clin Invest , vol.58 , pp. 731-741
    • Harker, L.A.1    Ross, R.2    Slichter, S.J.3    Scott, C.R.4
  • 37
    • 0016390789 scopus 로고
    • Homocystinemia: Vascular injury and arterial thrombosis
    • Harker LA, Slichter SJ, Scott CR, and Ross R. Homocystinemia: vascular injury and arterial thrombosis. N Engl J Med 291: 537-543, 1974.
    • (1974) N Engl J Med , vol.291 , pp. 537-543
    • Harker, L.A.1    Slichter, S.J.2    Scott, C.R.3    Ross, R.4
  • 38
    • 0023664723 scopus 로고
    • The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells
    • Heinecke JW, Rosen H, Suzuki LA, and Chait A. The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. J Biol Chem 262: 10098-10103, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 10098-10103
    • Heinecke, J.W.1    Rosen, H.2    Suzuki, L.A.3    Chait, A.4
  • 40
    • 0034647013 scopus 로고    scopus 로고
    • Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase
    • Hollenberg SM, Broussard M, Osman J, and Parrillo JE. Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase. Circ Res 86: 774-778, 2000.
    • (2000) Circ Res , vol.86 , pp. 774-778
    • Hollenberg, S.M.1    Broussard, M.2    Osman, J.3    Parrillo, J.E.4
  • 42
    • 27744467308 scopus 로고    scopus 로고
    • Molecular targeting by homocysteine: A mechanism for vascular pathogenesis
    • Jacobsen DW, Catanescu O, Dibello PM, and Barbato JC. Molecular targeting by homocysteine: a mechanism for vascular pathogenesis. Clin Chem Lab Med 43: 1076-1083, 2005.
    • (2005) Clin Chem Lab Med , vol.43 , pp. 1076-1083
    • Jacobsen, D.W.1    Catanescu, O.2    Dibello, P.M.3    Barbato, J.C.4
  • 45
    • 0042810670 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidases: Specific features, expression, and regulation
    • Lassegue B and Clempus RE. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol 285: R277-R297, 2003.
    • (2003) Am J Physiol , vol.285
    • Lassegue, B.1    Clempus, R.E.2
  • 46
    • 28344446460 scopus 로고    scopus 로고
    • Mechanisms of homocysteine-induced atherothrombosis
    • Lentz SR. Mechanisms of homocysteine-induced atherothrombosis. J Thromb Haemost 3: 1646-1654, 2005.
    • (2005) J Thromb Haemost , vol.3 , pp. 1646-1654
    • Lentz, S.R.1
  • 47
    • 0033826673 scopus 로고    scopus 로고
    • Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice
    • Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, and Faraci FM. Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice. Am J Physiol 279: H970-H975, 2000.
    • (2000) Am J Physiol , vol.279
    • Lentz, S.R.1    Erger, R.A.2    Dayal, S.3    Maeda, N.4    Malinow, M.R.5    Heistad, D.D.6    Faraci, F.M.7
  • 48
    • 4644257043 scopus 로고    scopus 로고
    • Homocysteine: Is it a clinically important cardiovascular risk factor?
    • Lentz SR and Haynes WG. Homocysteine: is it a clinically important cardiovascular risk factor? Clev Clin J Med 71: 729-734, 2004.
    • (2004) Clev Clin J Med , vol.71 , pp. 729-734
    • Lentz, S.R.1    Haynes, W.G.2
  • 54
    • 0029938389 scopus 로고    scopus 로고
    • Homocysteine induced arteriosclerosis-like alterations of the aorta in normotensive and hypertensive rats following application of high doses of methionine
    • Matthias D, Becker CH, Riezler R, and Kindling PH. Homocysteine induced arteriosclerosis-like alterations of the aorta in normotensive and hypertensive rats following application of high doses of methionine. Atherosclerosis 122: 201-216, 1996.
    • (1996) Atherosclerosis , vol.122 , pp. 201-216
    • Matthias, D.1    Becker, C.H.2    Riezler, R.3    Kindling, P.H.4
  • 61
    • 20444471138 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase plays a minor role in inhibition of arterial thrombus formation
    • Ozuyaman B, Godecke A, Kusters S, Kirchhoff E, Scharf RE, and Schrader J. Endothelial nitric oxide synthase plays a minor role in inhibition of arterial thrombus formation. Thromb Haemost 93: 1161-1167, 2005.
    • (2005) Thromb Haemost , vol.93 , pp. 1161-1167
    • Ozuyaman, B.1    Godecke, A.2    Kusters, S.3    Kirchhoff, E.4    Scharf, R.E.5    Schrader, J.6
  • 62
    • 0023094333 scopus 로고
    • Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor
    • Parthasarathy S. Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor. Biochim Biophys Acta 917: 337-340, 1987.
    • (1987) Biochim Biophys Acta , vol.917 , pp. 337-340
    • Parthasarathy, S.1
  • 66
    • 34247374843 scopus 로고    scopus 로고
    • Prothrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia
    • Sauls DL, Arnold EK, Bell CW, Allen JC, and Hoffman M. Prothrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia. Thromb Res 120: 117-126, 2007.
    • (2007) Thromb Res , vol.120 , pp. 117-126
    • Sauls, D.L.1    Arnold, E.K.2    Bell, C.W.3    Allen, J.C.4    Hoffman, M.5
  • 67
    • 33644553466 scopus 로고    scopus 로고
    • Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: A potential mechanism of the thrombotic tendency in hyperhomocysteinemia
    • Sauls DL, Lockhart E, Warren ME, Lenkowski A, Wilhelm SE, and Hoffman M. Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia. Biochemistry 45: 2480-2487, 2006.
    • (2006) Biochemistry , vol.45 , pp. 2480-2487
    • Sauls, D.L.1    Lockhart, E.2    Warren, M.E.3    Lenkowski, A.4    Wilhelm, S.E.5    Hoffman, M.6
  • 68
    • 0141450396 scopus 로고    scopus 로고
    • Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: Implications for the mechanism of thrombosis in hyperhomocysteinemia
    • Sauls DL, Wolberg AS, and Hoffman M. Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: implications for the mechanism of thrombosis in hyperhomocysteinemia. J Thromb Haemost 1: 300-306, 2003.
    • (2003) J Thromb Haemost , vol.1 , pp. 300-306
    • Sauls, D.L.1    Wolberg, A.S.2    Hoffman, M.3
  • 70
    • 32044445028 scopus 로고    scopus 로고
    • Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit
    • Shukla N, Koupparis A, Jones RA, Angelini GD, Persad R, and Jeremy JY. Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit. Eur J Pharmacol 531: 201-208, 2006.
    • (2006) Eur J Pharmacol , vol.531 , pp. 201-208
    • Shukla, N.1    Koupparis, A.2    Jones, R.A.3    Angelini, G.D.4    Persad, R.5    Jeremy, J.Y.6
  • 71
    • 33644855617 scopus 로고    scopus 로고
    • Homocysteine: Call off the funeral
    • Spence JD. Homocysteine: call off the funeral. Stroke 37: 282-283, 2006.
    • (2006) Stroke , vol.37 , pp. 282-283
    • Spence, J.D.1
  • 72
    • 0022552919 scopus 로고
    • Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
    • Starkebaum G and Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 77: 1370-1376, 1986.
    • (1986) J Clin Invest , vol.77 , pp. 1370-1376
    • Starkebaum, G.1    Harlan, J.M.2
  • 73
    • 33846250329 scopus 로고    scopus 로고
    • Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress
    • Suematsu N, Ojaimi C, Kinugawa S, Wang Z, Xu X, Koller A, Recchia FA, and Hintze TH. Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress. Circulation 115: 255-262, 2007.
    • (2007) Circulation , vol.115 , pp. 255-262
    • Suematsu, N.1    Ojaimi, C.2    Kinugawa, S.3    Wang, Z.4    Xu, X.5    Koller, A.6    Recchia, F.A.7    Hintze, T.H.8
  • 76
    • 33644798431 scopus 로고    scopus 로고
    • Vascular dysfunction produced by hyperhomocysteinemia is more severe in the presence of low folate
    • Symons JD, Rutledge JC, Simonsen U, and Pattathu RA. Vascular dysfunction produced by hyperhomocysteinemia is more severe in the presence of low folate. Am J Physiol 290: H181-H191, 2006.
    • (2006) Am J Physiol , vol.290
    • Symons, J.D.1    Rutledge, J.C.2    Simonsen, U.3    Pattathu, R.A.4
  • 79
    • 4444367705 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta
    • Tasatargil A, Dalaklioglu S, and Sadan G. Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta. Pharmacology 72: 99-105, 2004.
    • (2004) Pharmacology , vol.72 , pp. 99-105
    • Tasatargil, A.1    Dalaklioglu, S.2    Sadan, G.3
  • 80
    • 33846928244 scopus 로고    scopus 로고
    • Homocysteine-induced changes in vascular reactivity of guinea-pig pulmonary arteries: Role of the oxidative stress and poly (ADP-ribose) polymerase activation
    • Tasatargil A, Sadan G, and Karasu E. Homocysteine-induced changes in vascular reactivity of guinea-pig pulmonary arteries: role of the oxidative stress and poly (ADP-ribose) polymerase activation. Pulm Pharmacol Ther 20: 265-272, 2007.
    • (2007) Pulm Pharmacol Ther , vol.20 , pp. 265-272
    • Tasatargil, A.1    Sadan, G.2    Karasu, E.3
  • 81
    • 0029051274 scopus 로고
    • Increased lipid peroxidation as a mechanism of methionine-induced atherosclerosis in rabbits
    • Toborek M, Kopieczna-Grzebieniak E, Drozdz M, and Wieczorek M. Increased lipid peroxidation as a mechanism of methionine-induced atherosclerosis in rabbits. Atherosclerosis 115: 217-224, 1995.
    • (1995) Atherosclerosis , vol.115 , pp. 217-224
    • Toborek, M.1    Kopieczna-Grzebieniak, E.2    Drozdz, M.3    Wieczorek, M.4
  • 82
  • 85
    • 0035830874 scopus 로고    scopus 로고
    • Homocysteine inhibits inactivation of factor Va by activated protein C
    • Undas A, Williams EB, Butenas S, Orfeo T, and Mann KG. Homocysteine inhibits inactivation of factor Va by activated protein C. J Biol Chem 276: 4389-4397, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 4389-4397
    • Undas, A.1    Williams, E.B.2    Butenas, S.3    Orfeo, T.4    Mann, K.G.5
  • 86
    • 0036309974 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: Morphological and functional evidence for increased peroxynitrite formation
    • Ungvari Z, Csiszar A, Bagi Z, and Koller A. Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation. Am J Pathol 161: 145-153, 2002.
    • (2002) Am J Pathol , vol.161 , pp. 145-153
    • Ungvari, Z.1    Csiszar, A.2    Bagi, Z.3    Koller, A.4
  • 87
    • 0037339694 scopus 로고    scopus 로고
    • Increased superoxide production in coronary arteries in hyperhomocysteinemia: Role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase
    • Ungvari Z, Csiszar A, Edwards JG, Kaminski PM, Wolin MS, Kaley G, and Koller A. Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase. Arterioscler Thromb Vasc Biol 23: 418-424, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 418-424
    • Ungvari, Z.1    Csiszar, A.2    Edwards, J.G.3    Kaminski, P.M.4    Wolin, M.S.5    Kaley, G.6    Koller, A.7
  • 88
    • 0032787873 scopus 로고    scopus 로고
    • Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia
    • Ungvari Z, Pacher P, Rischak K, Szollar L, and Koller A. Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia. Arterioscler Thromb Vasc Biol 19: 1899-1904, 1999.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1899-1904
    • Ungvari, Z.1    Pacher, P.2    Rischak, K.3    Szollar, L.4    Koller, A.5
  • 91
    • 3042698674 scopus 로고    scopus 로고
    • Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia
    • Vitvitsky V, Dayal S, Stabler S, Zhou Y, Wang H, Lentz SR, and Banerjee R. Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia. Am J Physiol 287: R39-R46, 2004.
    • (2004) Am J Physiol , vol.287
    • Vitvitsky, V.1    Dayal, S.2    Stabler, S.3    Zhou, Y.4    Wang, H.5    Lentz, S.R.6    Banerjee, R.7
  • 92
    • 0037926903 scopus 로고    scopus 로고
    • Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation
    • Wang H, Jiang X, Yang F, Gaubatz JW, Ma L, Magera MJ, Yang X, Berger PB, Durante W, Pownall HJ, and Schafer AI. Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation. Blood 101: 3901-3907, 2003.
    • (2003) Blood , vol.101 , pp. 3901-3907
    • Wang, H.1    Jiang, X.2    Yang, F.3    Gaubatz, J.W.4    Ma, L.5    Magera, M.J.6    Yang, X.7    Berger, P.B.8    Durante, W.9    Pownall, H.J.10    Schafer, A.I.11
  • 93
    • 2642513835 scopus 로고    scopus 로고
    • Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice
    • Wang L, Jhee KH, Hua X, DiBello PM, Jacobsen DW, and Kruger WD. Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice. Cir Res 94: 1318-1324, 2004.
    • (2004) Cir Res , vol.94 , pp. 1318-1324
    • Wang, L.1    Jhee, K.H.2    Hua, X.3    DiBello, P.M.4    Jacobsen, D.W.5    Kruger, W.D.6
  • 96
    • 0036144873 scopus 로고    scopus 로고
    • Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice
    • Weiss N, Heydrick S, Zhang YY, Bierl C, Cap A, and Loscalzo J. Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice. Arterioscler Thromb Vasc Biol 22: 34-41, 2002.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 34-41
    • Weiss, N.1    Heydrick, S.2    Zhang, Y.Y.3    Bierl, C.4    Cap, A.5    Loscalzo, J.6
  • 97
    • 0035940411 scopus 로고    scopus 로고
    • Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction
    • Weiss N, Zhang YY, Heydrick S, Bierl C, and Loscalzo J. Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction. Proc Natl Acad Sci U S A 98: 12503-12508, 2001.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12503-12508
    • Weiss, N.1    Zhang, Y.Y.2    Heydrick, S.3    Bierl, C.4    Loscalzo, J.5
  • 100
    • 1642504386 scopus 로고    scopus 로고
    • Hyperhomocysteinemia activates NF-kappaB and inducible nitric oxide synthase in the kidney
    • Zhang F, Siow YL, and O K. Hyperhomocysteinemia activates NF-kappaB and inducible nitric oxide synthase in the kidney. Kidney Int 65: 1327-1338, 2004.
    • (2004) Kidney Int , vol.65 , pp. 1327-1338
    • Zhang, F.1    Siow, Y.L.2
  • 102
    • 17144419252 scopus 로고    scopus 로고
    • Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice
    • Zhou J, Lhotak S, Hilditch BA, and Austin RC. Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 111: 1814-1821, 2005.
    • (2005) Circulation , vol.111 , pp. 1814-1821
    • Zhou, J.1    Lhotak, S.2    Hilditch, B.A.3    Austin, R.C.4
  • 103
    • 0035573652 scopus 로고    scopus 로고
    • Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice
    • Zhou J, Moller J, Danielsen CC, Bentzon J, Ravn HB, Austin RC, and Falk E. Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 21: 1470-1476, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1470-1476
    • Zhou, J.1    Moller, J.2    Danielsen, C.C.3    Bentzon, J.4    Ravn, H.B.5    Austin, R.C.6    Falk, E.7
  • 104
    • 0037497965 scopus 로고    scopus 로고
    • Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice
    • Zhou J, Moller J, Ritskes-Hoitinga M, Larsen ML, Austin RC, and Falk E. Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice. Atherosclerosis 168: 255-262, 2003.
    • (2003) Atherosclerosis , vol.168 , pp. 255-262
    • Zhou, J.1    Moller, J.2    Ritskes-Hoitinga, M.3    Larsen, M.L.4    Austin, R.C.5    Falk, E.6
  • 106
    • 0036199685 scopus 로고    scopus 로고
    • Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
    • Zou MH, Shi C, and Cohen RA. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest 109: 817-826, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 817-826
    • Zou, M.H.1    Shi, C.2    Cohen, R.A.3


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