Rosiglitazone reduces serum homocysteine levels, smooth muscle proliferation, and intimal hyperplasia in Sprague-Dawley rats fed a high methionine diet

Metabolism: Clinical and Experimental

Volumn 54, Issue 5, 2005, Pages 645-652

  Murthy, Subramanyam N ^a   Obregon, Demian F ^a   Chattergoon, Natasha N ^a   Fonseca, Neil A ^a   Mondal, Debasis ^a   Dunne, Jeffrey B ^a   Diez, Jose G ^a   Jeter Jr , James R ^a   Kadowitz, Philip J ^a   Agrawal, Krishna C ^a   McNamara, Dennis B ^a   Fonseca, Vivian A ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOCYSTEINE; METHIONINE; ROSIGLITAZONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BALLOON CATHETER; CAROTID ARTERY; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; EPITHELIUM HYPERPLASIA; FEMALE; LIVER; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 20944432916     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2004.12.008     Document Type: Article

References (46)

1. K.S. McCully Vascular pathology of homocystinemia-implication for the pathogenesis of arteriosclerosis Am. J. Pathol. 56 1 1969 111 128
2. K.S. McCully Chemical pathology of homocysteine. I. Atherogenesis Ann. Clin. Lab. Sci. 24 1 1994 27 59
3. S.P. Stabler Vitamins, homocysteine, and cognition Am. J. Clin. Nutr. 78 2003 359 360
4. M.Y. Tsai, N.Q. Hanson, M.K. Bignell, and K.A. Schwichtenberg Simultaneous detection and screening of T833C and G919A mutations of the cystathionine beta-synthase gene by single-strand conformational polymorphism Clin. Biochem. 5 1996 473 477
5. D. Rothenbacher, H.G. Fischer, A. Hoffmeister, M.M. Hoffmann, W. Marz, and G. Bode Homocysteine and methylenetetrahydrofolate reductase genotype: association with risk of coronary heart disease and relation to inflammatory, hemostatic, and lipid parameters Atherosclerosis 162 2002 193 200
6. C. Desouza, M. Keebler, D.B. McNamara, and V.A. Fonseca Drugs affecting homocysteine metabolism: impact on cardiovascular risk Drugs 62 2002 605 616
7. B. Hultberg Modulation of extra cellular homocysteine concentration in human cell lines Clin. Chim. Acta 330 2003 151 159
8. A. Sakamoto, Y. Nishimura, H. Ono, and N. Sakura Betaine and homocysteine concentrations in foods Pediatr. Int. 44 4 2002 409 413
9. J. Selhub, P.F. Jacques, A.G. Bostom, R.B. D'Agostino, P.W. Wilson, and A.J. Belanger Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis N. Engl. J. Med. 332 1995 286 291
10. J.Y. Streifler, N. Rosenberg, A. Chetrit, R. Eskaraev, B.A. Sela, and R. Dardik Cerebrovascular events in patients with significant stenosis of the carotid artery are associated with hyperhomocysteinemia and platelet antigen-1 (Leu33Pro) polymorphism Stroke 32 2001 2753 2758
11. O. Nygard, J.E. Nordrehaug, H. Refsum, P.M. Ueland, M. Farstad, and S.E. Vollset Plasma homocysteine levels and mortality in patients with coronary artery disease N. Engl. J. Med. 337 1997 230 236
12. P.M. Ueland, and H. Resfsum Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy J. Lab. Clin. Med. 114 1989 473 501
13. M.N. Munshi, A. Stone, L. Fink, and V.A. Fonseca Hyperhomocysteinemia following a methionine load in patients with non-insulin-dependent diabetes mellitus and macrovascular disease Metabolism 45 1 1996 133 135
14. K.J. Lievers, L.A. Kluijtmans, S.G. Heil, G.H. Boers, P. Verhoef, and D. van Oppenraay-Emmerzaal A 31 bp VNTR in the cystathionine beta-synthase (CBS) gene is associated with reduced CBS activity and elevated post-load homocysteine levels Eur. J. Hum. Genet. 9 8 2001 583 589
15. A.D. Korczyn Homocysteine, stroke and dementia Stoke 33 2002 2343 2344
16. S.A. Kojoglanian, M.B. Jorgensen, G. Wolde-Tsadik, R.J. Burchette, and V.J. Aharonian Restenosis in intervened coronaries with hyperhomocysteinemia (RICH) Am. Heart J. 146 6 2003 1077 1081
17. A.P. Burke, V.A. Fonseca, F. Kolodgie, A. Zieske, L. Fink, and R. Virmani Increased serum homocysteine and sudden death resulting from coronary atherosclerosis with fibrous plaques Arterioscler. Thromb. Vasc. Biol. 22 2002 1936 1941
18. S.C. Tyagi Homocyst(e)ine and heart disease: Pathophysiology of extracellular matrix Clin. Exp. Hypertens. 21 3 1999 181 198
19. G. Wang, C.W. Woo, F.L. Sung, Y.L. Siow, and K. O Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: Role of chemokine and adhesion molecules Arterioscler. Thromb. Vasc. Biol. 22 11 2002 1777 1783
20. H. Morita, H. Kurihara, S. Yoshida, Y. Saito, T. Shindo, and Y. Oh-Hashi Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury Circulation 103 2001 133 140
21. F.N. Southern, N. Cruz, L.M. Fink, C.A. Cooney, G.W. Barone, and J.F. Eidt Hyperhomocysteinemia increases intimal hyperplasia in a rat carotid endarterectomy model J. Vasc. Surg. 28 1998 909 918
22. T.P. Smith, C.P. Cruz, A.T. Brown, J.F. Eidt, and M.M. Moursi Folate supplementation inhibits intimal hyperplasia induced by a high-homocysteine diet in a rat carotid endarterectomy model J. Vasc. Surg. 34 2001 474 481
23. C.V. Desouza, S.N. Murthy, J. Diez, B. Dunne, A.S. Matta, and V.A. Fonseca Differential effects of peroxisome proliferator activator receptor-alpha and gamma ligands on intimal hyperplasia after balloon catheter-induced vascular injury in Zucker rats J. Cardiovasc. Pharmacol. Ther. 8 4 2003 297 306
24. S.H. Choi, D.H. Choi, Y.K. Ko, Y.S. Chang, Y.L. Cho, and S.K. Lim Preventive effects of rosiglitazone on restenosis after coronary stenting in patients with type-2 diabetes (Abstract) Diabetes 52 Suppl. 1 2003 A19 [abstract 82-OR]
25. K. Yamakawa, M. Hosoi, H. Koyama, S. Tanaka, S. Fukumoto, and H. Morii Peroxisome proliferator-activated receptor-gamma agonists increase vascular endothelial growth factor expression in human vascular smooth muscle cells Biochem. Biophys. Res. Commun. 271 2000 571 574
26. N. Berthiaume, A.K. Mika, and B.A. Zinker Development of insulin resistance and endothelin-1 levels in the Zucker fatty rat Metabolism 52 7 2003 845 849
27. S.H. Mudd, J.D. Finkelstein, F. Irreverre, and L. Laster Transsulfuration in mammals J. Biol. Chem. 240 11 1965 4382 4392
28. N.K. Schiller, and D.B. McNamara Balloon catheter vascular injury of the alloxan-induced diabetic rabbit: the role of insulin-like growth factor-1 Mol. Cell. Biochem. 202 1-2 1999 159 167
29. T. Nishibe, K. Miyazaki, F. Kudo, J. Flores, K. Miyazaki, and M. Nagato Induction of angiotensin converting enzyme in neointima after intravascular stent placement Int. Angiol. 21 3 2002 250 255
30. L.A. Poirier, C.K. Wise, R.R. Delongchamp, and R. Sinha Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet Cancer Epidemiol. Biomarkers Prev. 10 6 2001 649 655
31. A. Dicker-Brown, V.A. Fonseca, L.M. Fink, and P.A. Kern The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-beta-synthase: studies in hepatocytes Atherosclerosis 158 2 2001 297 301
32. V.A. Fonseca, M. Keebler, A. Dicker-Brown, C. Desouza, L.A. Poirier, and S.N. Murthy The effect of troglitazone on plasma homocysteine, hepatic and red cell S-adenosylmethionine and S-adenosylhomocysteine and enzymes in homocysteine metabolism in Zucker rats Metabolism 51 2002 783 786
33. S. Murthy, A.S. Matta, N.A. Fonseca, D.F. Obregon, D. Mondal, and D. McNamara Rosiglitazone stimulates hepatic cystathionine beta synthase activity but does not affect plasma homocysteine levels in Zucker fatty rats. American Diabetes Association Meeting, Orlando Diabetes 53 2004 A555
34. S. Dayal, T. Bottiglieri, E. Arning, N. Maeda, M.R. Malinow, and C.D. Sigmund Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine β-synthase-deficient mice Circ. Res. 88 2001 1203 1209
35. A.M. Troen, E. Lutgens, D.E. Smith, I.H. Rosenberg, and J. Selhub The atherogenic effect of excess methionine intake Proc. Natl. Acad. Sci. U. S. A. 100 25 2003 15089 15094
36. P. Chen, R. Poddar, E.V. Tipa, P.M. Dibello, C.D. Moravec, and K. Robinson Homocysteine metabolism in cardiovascular cells and tissues: implications for hyperhomocysteinemia and cardiovascular disease Adv. Enzyme Regul. 39 1999 93 109
37. J.D. Finkelstein Pathways and regulation of homocysteine metabolism in mammals Semin. Thromb. Hemost. 26 3 2000 219 225
38. L. Bao, C. Vlcek, V. Paces, and J.P. Kraus Identification and tissue distribution of human cystathionine beta-synthase mRNA isoforms Arch. Biochem. Biophys. 350 1 1998 95 103
39. C. Furman, Z. Luo, K. Walsh, N. Duverger, C. Copin, and J.C. Fruchart Systemic tissue inhibitor of metalloproteinase-1 gene delivery reduces neointimal hyperplasia in balloon-injured rat carotid artery FEBS Lett. 531 2 2002 122 126
40. C. Chen, S.M. Surowiec, A.H. Morsy, and M. Ma Intraperitoneal infusion of homocysteine increases intimal hyperplasia in balloon-injured rat carotid arteries Atherosclerosis 160 1 2002 103 114
41. Y.J. Suzuki, M.V. Lorenzi, S.S. Shi, R.M. Day, and J.B. Blumberg Homocysteine exerts cell type-specific inhibition of AP-1 transcription factor Free Radic. Biol. Med. 28 1 2000 39 45
42. S.T. de Dios, D. Bruemmer, R.J. Dilley, M.E. Ivey, G.L. Jennings, and R.E. Law Inhibitory activity of clinical thiazolidinedione peroxisome proliferator activating receptor-gamma ligands toward internal mammary artery, radial artery, and saphenous vein smooth muscle cell proliferation Circulation 107 2003 2548 2550
43. T. Takagi, T. Akasaka, A. Yamamuro, Y. Honda, T. Hozumi, and S. Morioka Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with non-insulin dependent diabetes mellitus: a serial intravascular ultrasound study J. Am. Coll. Cardiol. 36 5 2000 1529 1535
44. T. Takagi, A. Yamamuro, K. Tamita, K. Yamabe, M. Katayama, and S. Mizoguchi Pioglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with type 2 diabetes mellitus: an intravascular ultrasound scanning study Am. Heart J. 146 2003 E5
45. H. Lange, H. Suryapranata, G. De Luca, C. Borner, J. Dille, and K. Kallmayer Folate therapy and in-stent restenosis after coronary stenting N. Engl. J. Med. 350 2004 2673 2681
46. J.F. Toole, M.R. Malinow, L.E. Chambless, J.D. Spence, L.C. Pettigrew, and V.J. Howard Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial JAMA 291 2004 565 575