Neointimal hyperplasia in balloon-injured rat carotid arteries: The influence of hyperhomocysteinemia

Journal of Vascular Surgery

Volumn 35, Issue 1, 2002, Pages 158-165

  Cook, Judith W ^a,b   Malinow, M Rene ^a,c   Moneta, Gregory L ^a,b,d   Taylor, Lloyd M ^a,b,d   Orloff, Susan L ^a,d,e  

^a Oregon Health Sciences University ^*

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d PORTLAND VA MEDICAL CENTER   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTIN; FOLIC ACID; HOMOCYSTEINE; METHIONINE;

ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTERY OCCLUSION; ARTICLE; BALLOON OCCLUSION; COMMON CAROTID ARTERY; COMPUTER AIDED DESIGN; CONTROLLED STUDY; HYPERHOMOCYSTEINEMIA; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; SCORING SYSTEM; STAINING; ANIMAL; BALLOON DILATATION; BLOOD; CAROTID ARTERY INJURY; DISEASE MODEL; HYPERPLASIA; IMAGE PROCESSING; INJURY; INTIMA; LEWIS RAT; MALE; PATHOLOGY; TIME;

ANIMALS; BALLOON DILATATION; CAROTID ARTERY INJURIES; CAROTID ARTERY, COMMON; DISEASE MODELS, ANIMAL; HOMOCYSTEINE; HYPERHOMOCYSTEINEMIA; HYPERPLASIA; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; RATS; RATS, INBRED LEW; TIME FACTORS; TUNICA INTIMA;

EID: 0036363436     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1067/mva.2002.118819     Document Type: Article

References (41)

1. Schwartz SM, de Blois D, O'Brien ER. The intima: soil for atherosclerosis and rcstcnosis. Circ Res 1995;77:445-65.
2. Golledge J, Cuming R, Ellis M, Beattie DK, Davies AH, Greenhalgh RM. Clinical follow-up rather than duplex surveillance after carotid endarterectomy. J Vasc Surg 1997;25:55.
3. Healy DA, Zierler RE, Nicholls SC, et al. Long-term follow-up and clinical outcome of carotid restenosis. J Vasc Surg 1989;10:662.
4. Davies MG, Hagen PO. Pathobiology of intimal hyperplasia. Br J Surg 1994;81:1254-69.
5. Taylor LM, Edwards JM, Porter JP. Present status of reversed vein bypass grafting: five-year results of a modern series. J Vasc Surg 1990;11:193.
6. Leather RP, Fitzgerald K. Personal communication from Vascular Data Registry, Department of Surgery, Albany Medical College. Oct 19, 1992.
7. Cook JW, Schuman ES, Standage BA, Heinl P. Patency and flow characteristics using stapled vascular anastomoses in dialysis grafts: a prospective, randomized evaluation. Am J Surg. In press 2000.
8. Hodges T, Fillinger M, Zwolac R, et al. Longitudinal comparison of dialysis access methods: risk factors for failure. J Vasc Surg 1997;26:1009-19.
9. McGill HC. The relationship of dietary cholesterol to scrum cholesterol concentration and to atherosclerosis in man. Am J Clin Nutr 1979;32:2664-702.
10. Tell GS, Crouse JR, Furberg CD. Relation between blood lipid, lipoproteins and cerebrovascular atherosclerosis. Stroke 1998;19:423-30.
11. Malinow MR. Plasma homocyst(e)ine and arterial occlusive disease: a mini-review. Clin Chem 1994;40:173-6.
12. Mudd SH, Levy HL. Disorders in transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, Valle D, editors. The metabolic basis of inherited disease. 6th ed. New York: McGraw-Hill, 1989:693-734.
13. Kang SS, Wong PW, Bock HG, Horwitz A, Grix A. Intermediate hyperhomocysteinemia resulting from a compound heterozygosity of methylenetetrahydrofolate reductase mutation. Am J Hum Genet 1991;48:451-6.
14. Kang SS, Wong PWK, Norusis M. Homocysteinemia due to folate deficiency. Metabolism 1987;36:458-62.
15. Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 1994;60:2-11.
16. Brattstrom LE, Hardebo JE, Hultberg BL. Moderate homocysteinemia: a possible risk factor for arteriosclerotic cerebrovascular disease. Stroke 1984;15:55-9.
17. Boers GH, Smals AG, Trijbels FJ. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease. N Engl J Med 1985;313:709-15.
18. Refsum H, Ueland PM, N'ygard O, Vollset SE. Homocysteine and cardiovascular disease. Annu Rev Med 1998;49:31-62.
19. Malinow MR, Bostom AG, Krauss RM. Homocyst(e)ine, diet and cardiovascular diseases: a statement for health care professionals from the nutrition committee, American Heart Association. Circulation 1999;99:178-82.
20. Ambrosi P, Garcon D, Riberi A, et al. Association of mild hyperhomocysteinemia with cardiac graft vascular disease. Atherosclerosis 1998;138:347-50.
21. Pethig K, Hoffman A, Heublein B, Timke A, Gross G, Haverich A. Cardiac allograft vascular disease after orthotopic heart transplantation: methylenetetrahydrofolate reductase gene polymorphism C677T does not account for rapidly progressive forms. Transplantation 2000;69:442-5.
22. Malinow MR, Kang SS, Taylor LM, et al. Prevalence of hyperhomocyst(e) inemia in patients with peripheral arterial occlusive disease. Circulation 1989;79:1180-8.
23. Selhub J, Jaques PF, Bostom GA, et al. Association between plasma homocysteine concentration and extra-cerebral carotid artery stenosis. N Engl J Med 1995;332:286-91.
24. Beattie DK, Sian M, Greenhalgh RM, Davies AH. Influence of systemic factors on pre-existing intimal hyperplasia and their effect on the outcome of infrainguinal arterial reconstruction with vein. Br J Surg 1999;86:1441-7.
25. Taylor LM Jr, Moneta GM, Sexton GJ, Schuff RA, Porter JM. Prospective blinded study of the relationship between plasma homocysteine and progression of symptomatic peripheral arterial disease. J Vasc Surg 1999;29:8-21.
26. Starkebaum G. Harlan JM. Endothelial injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 1986;77:1370-6.
27. Harpel PC, Zang X, Borth W. Homocysteine and hemostasis: pathological mechanisms predisposing to thrombosis. J Nutr 1996;126: S1285-9.
28. Carmody BJ, Arora S, Avena R, Cosby K, Sidawy AN. Folic acid inhibits homocysteine-induced proliferation of human arterial smooth muscle cells. J Vasc Surg 1999;30:1121-8.
29. Chen C, Halkos ME, Surowiec SM, Conklin BS, Lin PH, Lumsden AB. Effects of homocysteine on smooth muscle cell proliferation in both cell culture and artery perfusion culture models. J Surg Res 2000;88:26-33.
30. Cipolla MJ, Willamson WK, Nehler ML, Taylor LM, Porter JM. The effect of elevated homocysteine levels on adrenergic vasoconstriction of human resistance arteries: the role of endothelium and reactive oxygen species. J Vasc Surg 2000;31:751-9.
31. Clowes AW, Reidy MA, Clowes MM. Mechanisms of stenosis after arterial injury. Lab Invest 1983;49:208-15.
32. Wilcken DE, Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest 1976;57:1079-82.
33. Osborne-Pellegrin MJ, Fau D. Effects of chronic absorption of dietary supplements of methionine and cystine on arterial morphology in the rat. Exp Mol Pathol 1992;56:49-59.
34. Southern FN, Cruz N, Fink LM, et al. Hyperhomocysteinemia increases intimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg 1998;28:909-19.
35. Robinson K, Arheart K, Refsum H, et al. Low circulating folate and vitamin B6 concentrations-risk factors for stroke, peripheral vascular disease, and coronary artery disease. Circulation 1998;97:437-43.
36. Bostom AG, Shemin D, Lapane KL, et al. Folate status is the major determinant of fasting total plasma homocysteine levels in maintenance dialysis patients. Atherosclerosis 1996;123:193-202.
37. Lentz SR, Sobey CG, Piegors DJ, et al. Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia. J Clin Invest 1996;98:24-9.
38. Lentz SR, Malinow MR, Piegors DJ, Bhopatkar-Teredesai M, Faraci FM, Heistad DD. Consequences of hyperhomocyst(e)inemia on vascular function in atherosclerotic monkeys. Arterioscler Thromb Vasc Biol 1997;17:2930-4.
39. Heijenbrok FJ, van der Wal AC, Pfaffendorf M, van Zwieten PA. Morphologic and functional consequences of intimal hyperplasia in the rat carotid artery. Naunyn Schmiedebergs Arch Pharmacol 1998;357:133-42.
40. Kocher O, Gabbiani F, Gabbiani G, et al. Phenotypic features of smooth muscle cells during the evolution of experimental carotid artery intimal thickening. Lab Invest 1991;65:459-70.
41. Indolfi C, Esposito G, Di Lorenzo E, et al. Smooth muscle cell proliferation is proportional to the degree of balloon injury in a rat model of angioplasty. Circulation 1995;92:1230-5.