The glutathione peroxidases

Cellular and Molecular Life Sciences

Volumn 57, Issue 13-14, 2000, Pages 1825-1835

  Arthur, J R ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Glutathione peroxidase; Knockouts; Overexpression; Peroxides; Selenium

Indexed keywords

ANTIOXIDANT; ARACHIDONIC ACID; GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; SELENIUM; SELENOPROTEIN;

ARACHIDONIC ACID METABOLISM; CELL LINE; DIETARY INTAKE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIPID PEROXIDATION; MOUSE; NONHUMAN; NUTRITIONAL REQUIREMENT; NUTRITIONAL VALUE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW;

ANIMALIA; MAMMALIA;

EID: 0034489653     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00000664     Document Type: Review

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8. Non-reactivity of the selenoenzyme glutathione peroxidase with enzymically hydroperoxidised phospholipids
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10. The refined structure of the selenoenzyne glutathione peroxidase at 0.2 nm resolution
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12. Expression, characterization and tissue distribution of a new cellular selenium-dependent glutathione peroxidase
13. Selenium-dependent glutathione peroxidase protein and activity: Immunological investigations on cellular and plasma enzymes
14. Purification and characterization of human plasma glutathione peroxidase: A selenoglycoprotein distinct from the known cellular enzyme
15. Primary structure of human plasma glutathione peroxidase deduced from cDNA sequences
16. Human kidney proximal tubules are the main source of plasma glutathione peroxidase
17. Human placenta makes extracellular glutathione peroxidase and secretes it into maternal circulation
18. Mouse plasma glutathione peroxidase: cDNA sequence analysis and renal proximal tubular expression and secretion
19. Expression of extracellular glutathione peroxidase in human and mouse gastrointestinal tract
20. Thyroidal extracellular glutathione peroxidase: A potential regulator of thyroid-hormone synthesis
21. Plasma selenium-dependent glutathione peroxidase: Cell of origin and secretion
22. Extracellular glutathione peroxidase mRNA and protein in human cell lines
23. The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase
24. Diversity of glutathione peroxidases Biothiols,-Pt-B-
25. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase
26. Phospholipid hydroperoxide glutathione peroxidase is a seleno-enzyme distinct from the classical glutathione peroxidase as evident from cDNA and amino acid sequencing
27. Reactivity of phospholipid hydroperoxide glutathione peroxidase with membrane and lipoprotein lipid hydroperoxides
28. Probing the presumed catalytic triad of selenium-containing peroxidases by mutational analysis of phospholipid hydroperoxide glutathione peroxidase (PHGPx)
29. Glutathione peroxidase revisited: Simulation of the catalytic cycle by computer-assisted molecular modelling
30. Probing the presumed catalytic triad of a selenium-containing peroxidase by mutational analysis
31. Phospholipid-hydroperoxide glutathione peroxidase: Genomic DNA, cDNA and deduced amino acid sequence
32. Phospholipid hydroperoxide glutathione peroxidase: Full-length pig blastocyst cDNA sequence and regulation by selenium status
33. Cloning and sequencing of the mouse cDNA encoding a phospholipid hydroperoxide glutathione peroxidase
34. Enzymatic and immunological measurements of soluble and membrane-bound phospholipid-hydroperoxide glutathione peroxidase
35. Rat phospholipid-hydroperoxide glutathione peroxidase: cDNA cloning and identification of multiple transcription and translation start sites
36. A mouse cDNA sequence for epididymal androgen-regulated proteins related to glutathione peroxidase
37. Sequence homology of androgen-regulated epididymal proteins with glutathione peroxidase in mice
38. In vitro expression of a mouse tissue specific glutathione-peroxidase like protein lacking the selenocysteine can protect stably transfected mammalian cells against oxidative damage
39. Tissue and developmental distribution, dependence upon testicular factors and attachment to spermatozoa of GPX-5, a murine epididymis-specific glutathione peroxidase
40. The majority of human glutathione peroxidase type 5 (GPX-5) transcripts are incorrectly spliced: Implications for the role of GPX-5 in the male reproductive tract
41. Expression of extracellular glutathione peroxidase type 5 (GPX-5) in the rat male reproductive tract
42. Molecular cloning of putative odorant-binding and odorant-metabolizing proteins
43. Biochemical function of selenium and its relation to vitamin E
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50. Tissue-specific regulation of selenoenzyme gene expression during selenium deficiency in rats
51. Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F-2-isoprostanes
52. Selenoenzymes regulate the activity of leukocyte 5-lipoxygenase via the peroxide tone
53. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products
54. Hydroperoxy fatty acid formation in selenium deficient rat platelets: Coupling of glutathione peroxidase to the lipoxygenase pathway
55. Evidence for specific selenium target tissues and new biologically important selenoproteins
56. The interactions between selenium and iodine deficiencies in man and animals
57. Intracellular glutathione peroxidases: Structure, regulation and function
58. Selenoprotein gene expression during selenium-repletion of selenium-deficient rats
59. Glutathione peroxidase protects cultured mammalian cells from the toxicity of adriamycin and paraquat
60. Heterologous expression of selenium-dependent glutathione peroxidase affords cellular resistance to paraquat
61. A T-cell model for the biological role of selenium-dependent glutathione peroxidase
62. Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants
63. Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase over-expression
64. Modulation of glutathione peroxidase activity in human vascular endothelial cells by fatty acids and the cytokine interleukin-1b
65. Thermosensitive phenotype of transgenic mice overproducing human glutathione peroxidases
66. Enhanced skin carcinogenesis in transgenic mice with high expression of glutathione peroxidase or both glutathione peroxidase and superoxide dismutase
67. Acetaminophen toxicity: Opposite effects of two forms of glutathione peroxidase
68. Over-expression of cellular glutathione peroxidase does not affect expression of plasma glutathione peroxidase or phospholipid hydroperoxide glutathione peroxidase in mice offered diets adequate or deficient in selenium
69. Increased resistance of GPX-1 transgenic mice to tumor promoter-induced loss of glutathione peroxidase activity in skin
70. Selenium and chromium deficiency during long-term home total parenteral nutrition in chronic idiopathic intestinal pseudoobstruction
71. Energy stress-induced dopamine loss in glutathione peroxidase over-expressing transgenic mice and in glutathione-depleted mesencephalic cultures
72. Transgenic mice overexpressing glutathione peroxidase are resistant to myocardial ischaemia reperfusion injury
73. Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia
74. Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidases in various tissues
75. Glutathione peroxidase knockout mice are susceptible to myocardial ischaemia reperfusion injury
76. Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice
77. Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress
78. Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats
79. Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats: Assessment of the roles of lipid peroxidation and selenoprotein P
80. Selenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids and protein
81. Glutathione peroxidase protects mice from viral-induced myocarditis
82. The effect of photochemical stress upon the lenses of normal and glutathione peroxidase-1 knockout mice
83. Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: Importance of an intracellular oxidant stress
84. Selenium-dependent glutathione peroxidase-GI is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine
85. mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins
86. Retinoic acid induces GPX-2 gene expression in MCF-7 human breast cancer cells
87. Plasma glutathione peroxidase reduces phosphatidylcholine hydroperoxide
88. Cloning of the mouse gene encoding plasma glutathione peroxidase: Organization, sequence and chromosomal localization
89. Tissue specific expression of the plasma glutathione peroxidase gene in rat kidney
90. Plasma glutathione peroxidase and its relationship to renal proximal tubule function
91. Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells
92. Dual function of the selenoprotein PHGPx during sperm maturation
93. Microsomal lipid peroxidation: Effect of vitamin E and its functional interaction with phospholipid hydroperoxide glutathione peroxidase
94. Interleukin-1-induced nuclear factor kappa B activation is inhibited by over-expression of phospholipid hydroperoxide glutathione peroxidase in a human endothelial cell line
95. Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase
96. Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway
97. Cellular glutathione peroxidase as a predominant scavenger of hydroperoxyeicosatetraenoic acids in rabbit alveolar macrophages