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Volumn 9, Issue 10, 2007, Pages 871-881

Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis

Author keywords

Apoptosis; Camptothecin; CREB; Mcl 1; Noxa

Indexed keywords

CAMPTOTHECIN; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN MCL 1; PROTEIN NOXA; PROTEIN P53; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EID: 35448964624     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.07589     Document Type: Article
Times cited : (50)

References (51)
  • 1
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H (1995). Mechanisms and genes of cellular suicide. Science 267 (5203), 1445-1449.
    • (1995) Science , vol.267 , Issue.5203 , pp. 1445-1449
    • Steller, H.1
  • 2
    • 0033593572 scopus 로고    scopus 로고
    • Cell death in development
    • Vaux DL and Korsmeyer SJ (1999). Cell death in development. Cell 96 (2), 245-254.
    • (1999) Cell , vol.96 , Issue.2 , pp. 245-254
    • Vaux, D.L.1    Korsmeyer, S.J.2
  • 3
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: A link between cancer genetics and chemotherapy
    • Johnstone RW, Ruefli AA, and Lowe SW (2002). Apoptosis: a link between cancer genetics and chemotherapy. Cell 108 (2), 153-164.
    • (2002) Cell , vol.108 , Issue.2 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 4
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN and Korsmeyer SJ (2004). Cell death: critical control points. Cell 116 (2), 205-219.
    • (2004) Cell , vol.116 , Issue.2 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 5
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R, and Wang X (1996). Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86 (1), 147-157.
    • (1996) Cell , vol.86 , Issue.1 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 6
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou H, Li Y, Liu X, and Wang X (1999). An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 274 (17), 11549-11556.
    • (1999) J Biol Chem , vol.274 , Issue.17 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4
  • 7
    • 0033519705 scopus 로고    scopus 로고
    • Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    • Shimizu S, Narita M, and Tsujimoto Y (1999). Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399 (6735), 483-487.
    • (1999) Nature , vol.399 , Issue.6735 , pp. 483-487
    • Shimizu, S.1    Narita, M.2    Tsujimoto, Y.3
  • 8
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory S and Adams JM (2002). The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2 (9), 647-656.
    • (2002) Nat Rev Cancer , vol.2 , Issue.9 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 9
    • 0036097786 scopus 로고    scopus 로고
    • Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
    • Puthalakath H and Strasser A (2002). Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 9 (5), 505-512.
    • (2002) Cell Death Differ , vol.9 , Issue.5 , pp. 505-512
    • Puthalakath, H.1    Strasser, A.2
  • 12
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong WX, Lindsten T, Ross AJ, MacGregor GR, and Thompson CB (2001). BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15 (12), 1481-1486.
    • (2001) Genes Dev , vol.15 , Issue.12 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 14
    • 0036728834 scopus 로고    scopus 로고
    • Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
    • Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, and Korsmeyer SJ (2002). Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2 (3), 183-192.
    • (2002) Cancer Cell , vol.2 , Issue.3 , pp. 183-192
    • Letai, A.1    Bassik, M.C.2    Walensky, L.D.3    Sorcinelli, M.D.4    Weiler, S.5    Korsmeyer, S.J.6
  • 15
    • 0034786019 scopus 로고    scopus 로고
    • BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
    • Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, and Korsmeyer SJ (2001). BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell 8 (3), 705-711.
    • (2001) Mol Cell , vol.8 , Issue.3 , pp. 705-711
    • Cheng, E.H.1    Wei, M.C.2    Weiler, S.3    Flavell, R.A.4    Mak, T.W.5    Lindsten, T.6    Korsmeyer, S.J.7
  • 16
    • 9744244990 scopus 로고    scopus 로고
    • The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA
    • Cartron PF, Gallenne T, Bougras G, Gautier F, Manero F, Vusio P, Meflah K, Vallette FM, and Juin P (2004). The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. Mol Cell 16 (5), 807-818.
    • (2004) Mol Cell , vol.16 , Issue.5 , pp. 807-818
    • Cartron, P.F.1    Gallenne, T.2    Bougras, G.3    Gautier, F.4    Manero, F.5    Vusio, P.6    Meflah, K.7    Vallette, F.M.8    Juin, P.9
  • 17
    • 7444243152 scopus 로고    scopus 로고
    • Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity
    • Harada H, Quearry B, Ruiz-Vela A, and Korsmeyer SJ (2004). Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity. Proc Natl Acad Sci USA 101 (43), 15313-15317.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.43 , pp. 15313-15317
    • Harada, H.1    Quearry, B.2    Ruiz-Vela, A.3    Korsmeyer, S.J.4
  • 18
    • 13944277343 scopus 로고    scopus 로고
    • BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
    • Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, and Newmeyer DD (2005). BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 17 (4), 525-535.
    • (2005) Mol Cell , vol.17 , Issue.4 , pp. 525-535
    • Kuwana, T.1    Bouchier-Hayes, L.2    Chipuk, J.E.3    Bonzon, C.4    Sullivan, B.A.5    Green, D.R.6    Newmeyer, D.D.7
  • 21
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang YH, Hertzberg R, Hecht S, and Liu LF (1985). Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 260 (27), 14873-14878.
    • (1985) J Biol Chem , vol.260 , Issue.27 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 22
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • Hsiang YH and Liu LF (1988). Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 48 (7), 1722-1726.
    • (1988) Cancer Res , vol.48 , Issue.7 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 23
    • 0035029153 scopus 로고    scopus 로고
    • Tumor cell death induced by topoisomerase- targeting drugs
    • Li TK and Liu LF (2001). Tumor cell death induced by topoisomerase- targeting drugs. Annu Rev Pharmacol Toxicol 41, 53-77.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 53-77
    • Li, T.K.1    Liu, L.F.2
  • 24
    • 0027139317 scopus 로고
    • Interaction between replication forks and topoisomerase I-DNA cleavable complexes: Studies in a cell-free SV40 DNA replication system
    • Tsao YP, Russo A, Nyamuswa G, Silber R, and Liu LF (1993). Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. Cancer Res 53 (24), 5908-5914.
    • (1993) Cancer Res , vol.53 , Issue.24 , pp. 5908-5914
    • Tsao, Y.P.1    Russo, A.2    Nyamuswa, G.3    Silber, R.4    Liu, L.F.5
  • 25
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • Morris EJ and Geller HM (1996). Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity. J Cell Biol 134 (3), 757-770.
    • (1996) J Cell Biol , vol.134 , Issue.3 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 26
    • 0030886788 scopus 로고    scopus 로고
    • Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: Effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases
    • Shimizu T and Pommier Y (1997). Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases. Leukemia 11 (8), 1238-1244.
    • (1997) Leukemia , vol.11 , Issue.8 , pp. 1238-1244
    • Shimizu, T.1    Pommier, Y.2
  • 27
    • 0027893001 scopus 로고
    • Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage
    • Slichenmyer WJ, Nelson WG, Slebos RJ, and Kastan MB (1993). Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res 53 (18), 4164-4168.
    • (1993) Cancer Res , vol.53 , Issue.18 , pp. 4164-4168
    • Slichenmyer, W.J.1    Nelson, W.G.2    Slebos, R.J.3    Kastan, M.B.4
  • 29
    • 27944457637 scopus 로고    scopus 로고
    • Puma(*)Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1
    • Mei Y, Du W, Yang Y, and Wu M (2005). Puma(*)Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1. Oncogene 24 (48), 7224-7237.
    • (2005) Oncogene , vol.24 , Issue.48 , pp. 7224-7237
    • Mei, Y.1    Du, W.2    Yang, Y.3    Wu, M.4
  • 30
    • 0029807603 scopus 로고    scopus 로고
    • Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: Evidence for a protease-dependent pathway that does not activate cysteine protease P32
    • Adjei PN, Kaufmann SH, Leung WY, Mao F, and Gores GJ (1996). Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32. J Clin Invest 98 (11), 2588-2596.
    • (1996) J Clin Invest , vol.98 , Issue.11 , pp. 2588-2596
    • Adjei, P.N.1    Kaufmann, S.H.2    Leung, W.Y.3    Mao, F.4    Gores, G.J.5
  • 31
    • 1542405872 scopus 로고    scopus 로고
    • Pharmacogenomic identification of targets for adjuvant therapy with the topoisomerase poison camptothecin
    • Carson JP, Zhang N, Frampton GM, Gerry NP, Lenburg ME, and Christman MF (2004). Pharmacogenomic identification of targets for adjuvant therapy with the topoisomerase poison camptothecin. Cancer Res 64 (6), 2096-2104.
    • (2004) Cancer Res , vol.64 , Issue.6 , pp. 2096-2104
    • Carson, J.P.1    Zhang, N.2    Frampton, G.M.3    Gerry, N.P.4    Lenburg, M.E.5    Christman, M.F.6
  • 33
    • 0030884103 scopus 로고    scopus 로고
    • PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
    • Marte BM and Downward J (1997). PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem Sci 22 (9), 355-358.
    • (1997) Trends Biochem Sci , vol.22 , Issue.9 , pp. 355-358
    • Marte, B.M.1    Downward, J.2
  • 35
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
    • Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, and Cohen P (1997). Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr Biol 7 (4), 261-269.
    • (1997) Curr Biol , vol.7 , Issue.4 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5    Reese, C.B.6    Cohen, P.7
  • 36
    • 22244454745 scopus 로고    scopus 로고
    • Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: Therapeutic implications
    • Fernandez Y, Verhaegen M, Miller TP, Rush JL, Steiner P, Opipari AW Jr, Lowe SW, and Soengas MS (2005). Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. Cancer Res 65 (14), 6294-6304.
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6294-6304
    • Fernandez, Y.1    Verhaegen, M.2    Miller, T.P.3    Rush, J.L.4    Steiner, P.5    Opipari Jr, A.W.6    Lowe, S.W.7    Soengas, M.S.8
  • 39
    • 0032484019 scopus 로고    scopus 로고
    • CREB is a regulatory target for the protein kinase Akt/PKB
    • Du K and Montminy M (1998). CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem 273 (49), 32377-32379.
    • (1998) J Biol Chem , vol.273 , Issue.49 , pp. 32377-32379
    • Du, K.1    Montminy, M.2
  • 40
    • 33846330908 scopus 로고    scopus 로고
    • Single-stranded RNA viruses inactivate the transcriptional activity of p53 but induce NOXA-dependent apoptosis via post-translational modifications of IRF-1, IRF-3 and CREB
    • Lallemand C, Blanchard B, Palmieri M, Lebon P, May E, and Tovey MG (2007). Single-stranded RNA viruses inactivate the transcriptional activity of p53 but induce NOXA-dependent apoptosis via post-translational modifications of IRF-1, IRF-3 and CREB. Oncogene 26 (3), 328-338.
    • (2007) Oncogene , vol.26 , Issue.3 , pp. 328-338
    • Lallemand, C.1    Blanchard, B.2    Palmieri, M.3    Lebon, P.4    May, E.5    Tovey, M.G.6
  • 41
    • 0037374548 scopus 로고    scopus 로고
    • Apoptotic susceptibility of cancer cells selected for camptothecin resistance: Gene expression profiling, functional analysis, and molecular interaction mapping
    • Reinhold WC, Kouros-Mehr H, Kohn KW, Maunakea AK, Lababidi S, Roschke A, Stover K, Alexander J, Pantazis P, Miller L, et al. (2003). Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping. Cancer Res 63 (5), 1000-1011.
    • (2003) Cancer Res , vol.63 , Issue.5 , pp. 1000-1011
    • Reinhold, W.C.1    Kouros-Mehr, H.2    Kohn, K.W.3    Maunakea, A.K.4    Lababidi, S.5    Roschke, A.6    Stover, K.7    Alexander, J.8    Pantazis, P.9    Miller, L.10
  • 42
    • 0027374488 scopus 로고
    • Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
    • Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, and Matsuda Y (1993). Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 268 (34), 25846-25856.
    • (1993) J Biol Chem , vol.268 , Issue.34 , pp. 25846-25856
    • Yano, H.1    Nakanishi, S.2    Kimura, K.3    Hanai, N.4    Saitoh, Y.5    Fukui, Y.6    Nonomura, Y.7    Matsuda, Y.8
  • 43
    • 1542305653 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
    • Hershko T and Ginsberg D (2004). Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J Biol Chem 279 (10), 8627-8634.
    • (2004) J Biol Chem , vol.279 , Issue.10 , pp. 8627-8634
    • Hershko, T.1    Ginsberg, D.2
  • 44
    • 0025012137 scopus 로고
    • Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13- acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line
    • Hijikata M, Kato N, Sato T, Kagami Y, and Shimotohno K (1990). Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13- acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line. J Virol 64 (10), 4632-4639.
    • (1990) J Virol , vol.64 , Issue.10 , pp. 4632-4639
    • Hijikata, M.1    Kato, N.2    Sato, T.3    Kagami, Y.4    Shimotohno, K.5
  • 45
    • 0346655211 scopus 로고    scopus 로고
    • BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
    • Kim JY, Ahn HJ, Ryu JH, Suk K, and Park JH (2004). BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J Exp Med 199 (1), 113-124.
    • (2004) J Exp Med , vol.199 , Issue.1 , pp. 113-124
    • Kim, J.Y.1    Ahn, H.J.2    Ryu, J.H.3    Suk, K.4    Park, J.H.5
  • 47
    • 0037022571 scopus 로고    scopus 로고
    • Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays
    • Sesto A, Navarro M, Burslem F, and Jorcano JL (2002). Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays. Proc Natl Acad Sci USA 99 (5), 2965-2970.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.5 , pp. 2965-2970
    • Sesto, A.1    Navarro, M.2    Burslem, F.3    Jorcano, J.L.4
  • 49
    • 0032772367 scopus 로고    scopus 로고
    • The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB
    • Wang JM, Chao JR, Chen W, Kuo ML, Yen JJ, and Yang-Yen HF (1999). The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol Cell Biol 19 (9), 6195-6206.
    • (1999) Mol Cell Biol , vol.19 , Issue.9 , pp. 6195-6206
    • Wang, J.M.1    Chao, J.R.2    Chen, W.3    Kuo, M.L.4    Yen, J.J.5    Yang-Yen, H.F.6
  • 50
    • 0030995164 scopus 로고    scopus 로고
    • Induction of BCL2 family member MCL1 as an early response to DNA damage
    • Zhan Q, Bieszczad CK, Bae I, Fornace AJ Jr, and Craig RW (1997). Induction of BCL2 family member MCL1 as an early response to DNA damage. Oncogene 14 (9), 1031-1039.
    • (1997) Oncogene , vol.14 , Issue.9 , pp. 1031-1039
    • Zhan, Q.1    Bieszczad, C.K.2    Bae, I.3    Fornace Jr, A.J.4    Craig, R.W.5
  • 51
    • 33745006592 scopus 로고    scopus 로고
    • The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
    • Alves NL, Derks IA, Berk E, Spijker R, van Lier RA, and Eldering E (2006). The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 24 (6), 703-716.
    • (2006) Immunity , vol.24 , Issue.6 , pp. 703-716
    • Alves, N.L.1    Derks, I.A.2    Berk, E.3    Spijker, R.4    van Lier, R.A.5    Eldering, E.6


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