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Volumn 25, Issue 10, 2007, Pages 2408-2418

Concise review: Role and function of the ubiquitin-proteasome system in mammalian stem and progenitor cells

Author keywords

Embryonic stem cells; Hematopoietic stem cells; Mesenchymal stem cells; Neural stem cells; Proteasome; Ubiquitin

Indexed keywords

PROTEASOME; UBIQUITIN;

EID: 35348886029     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0255     Document Type: Review
Times cited : (73)

References (218)
  • 2
    • 0036083396 scopus 로고    scopus 로고
    • The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
    • Glickman MH, Ciechanover A. The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction. Physiol Rev 2002;82:373-428.
    • (2002) Physiol Rev , vol.82 , pp. 373-428
    • Glickman, M.H.1    Ciechanover, A.2
  • 3
    • 33644859083 scopus 로고    scopus 로고
    • The ubiquitin proteolytic system
    • Ciechanover A. The ubiquitin proteolytic system. Neurology 2006;66:S7-S19.
    • (2006) Neurology , vol.66
    • Ciechanover, A.1
  • 4
    • 0032488846 scopus 로고    scopus 로고
    • The proteasome: Paradigm of a self-compartmentalizing protease
    • Baumeister W, Walz J, Zühl F et al. The proteasome: Paradigm of a self-compartmentalizing protease. Cell 1998;92:367-380.
    • (1998) Cell , vol.92 , pp. 367-380
    • Baumeister, W.1    Walz, J.2    Zühl, F.3
  • 5
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges D, Zwickl P, Baumeister W. The 26S proteasome: A molecular machine designed for controlled proteolysis. Annu Rev Biochem 1999;68:1015-1068.
    • (1999) Annu Rev Biochem , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 6
    • 0036678959 scopus 로고    scopus 로고
    • Role and function of the 26S proteasome in proliferation and apoptosis
    • Naujokat C, Hoffmann S. Role and function of the 26S proteasome in proliferation and apoptosis. Lab Invest 2002;82:965-980.
    • (2002) Lab Invest , vol.82 , pp. 965-980
    • Naujokat, C.1    Hoffmann, S.2
  • 7
    • 0036017391 scopus 로고    scopus 로고
    • Protein degradation and the generation of MHC class I-presented peptides
    • Rock KL, York IA, Saric T et al. Protein degradation and the generation of MHC class I-presented peptides. Adv Immunol 2002;80:1-70.
    • (2002) Adv Immunol , vol.80 , pp. 1-70
    • Rock, K.L.1    York, I.A.2    Saric, T.3
  • 8
    • 0842277344 scopus 로고    scopus 로고
    • The components of the proteasome and their role in MHC class I antigen processing
    • Krüger E, Kuckelkorn U, Sijts A et al. The components of the proteasome and their role in MHC class I antigen processing. Rev Physiol Biochem Pharmacol 2003;148:81-104.
    • (2003) Rev Physiol Biochem Pharmacol , vol.148 , pp. 81-104
    • Krüger, E.1    Kuckelkorn, U.2    Sijts, A.3
  • 9
    • 9644300915 scopus 로고    scopus 로고
    • The proteasome: A proteolytic nanomachine of cell regulation and waste disposal
    • Wolf DH, Hilt W. The proteasome: A proteolytic nanomachine of cell regulation and waste disposal. Biochim Biophys Acta 2004;1695:19-31.
    • (2004) Biochim Biophys Acta , vol.1695 , pp. 19-31
    • Wolf, D.H.1    Hilt, W.2
  • 10
    • 0346727127 scopus 로고    scopus 로고
    • Protein degradation and protection against misfolded and damaged proteins
    • Goldberg AL. Protein degradation and protection against misfolded and damaged proteins. Nature 2003;426:895-899.
    • (2003) Nature , vol.426 , pp. 895-899
    • Goldberg, A.L.1
  • 11
    • 9744227183 scopus 로고    scopus 로고
    • Ubiquitin: Structures, functions, mechanisms
    • Pickart CM, Eddins MJ. Ubiquitin: Structures, functions, mechanisms. Biochim Biophys Acta 2004;1695:55-72.
    • (2004) Biochim Biophys Acta , vol.1695 , pp. 55-72
    • Pickart, C.M.1    Eddins, M.J.2
  • 12
    • 0030897031 scopus 로고    scopus 로고
    • Structure of 20S proteasome from yeast at 2.4 Å resolution
    • Groll M, Ditzel L, Löwe J et al. Structure of 20S proteasome from yeast at 2.4 Å resolution. Nature 1997;386:463-471.
    • (1997) Nature , vol.386 , pp. 463-471
    • Groll, M.1    Ditzel, L.2    Löwe, J.3
  • 13
    • 0032483546 scopus 로고    scopus 로고
    • A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and elF3
    • Glickman MH, Rubin DM, Coux O et al. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and elF3. Cell 1998;94:615-623.
    • (1998) Cell , vol.94 , pp. 615-623
    • Glickman, M.H.1    Rubin, D.M.2    Coux, O.3
  • 14
    • 0034253588 scopus 로고    scopus 로고
    • Evolution and function of ubiquitin-like protein-conjugation systems
    • Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol 2000;2:E153-E157.
    • (2000) Nat Cell Biol , vol.2
    • Hochstrasser, M.1
  • 15
    • 3142745212 scopus 로고    scopus 로고
    • Ubiquitin-mediated proteolysis: An ideal pathway for systems biology analysis
    • Rechsteiner MC. Ubiquitin-mediated proteolysis: An ideal pathway for systems biology analysis. Adv Exp Med Biol 2004;547:49-59.
    • (2004) Adv Exp Med Biol , vol.547 , pp. 49-59
    • Rechsteiner, M.C.1
  • 16
    • 4143072546 scopus 로고    scopus 로고
    • DeRenzo C, Seydoux G. A clean start: Degradation of maternal proteins at the oocyt-to-embryo transition. Trends Cell Biol 2004;14:420-426.
    • DeRenzo C, Seydoux G. A clean start: Degradation of maternal proteins at the oocyt-to-embryo transition. Trends Cell Biol 2004;14:420-426.
  • 17
    • 33645541393 scopus 로고    scopus 로고
    • Degrade to create: Developmental requirements for ubiquitin-mediated proteolysis during early C. elegans embryogenesis
    • Bowerman B, Kurz T. Degrade to create: Developmental requirements for ubiquitin-mediated proteolysis during early C. elegans embryogenesis. Development 2006;133:773-784.
    • (2006) Development , vol.133 , pp. 773-784
    • Bowerman, B.1    Kurz, T.2
  • 18
    • 0037397606 scopus 로고    scopus 로고
    • The ubiquitin proteolytic system and pathogenesis of human diseases: A novel platform for mechanism-based drug targeting
    • Ciechanover A. The ubiquitin proteolytic system and pathogenesis of human diseases: A novel platform for mechanism-based drug targeting. Biochem Soc Trans 2003;31:474-481.
    • (2003) Biochem Soc Trans , vol.31 , pp. 474-481
    • Ciechanover, A.1
  • 19
    • 0842346198 scopus 로고    scopus 로고
    • Role of the ubiquitin-proteasome pathway in the diagnosis of human diseases
    • Golab J, Bauer TM, Daniel V et al. Role of the ubiquitin-proteasome pathway in the diagnosis of human diseases. Clin Chim Acta 2004;340:27-40.
    • (2004) Clin Chim Acta , vol.340 , pp. 27-40
    • Golab, J.1    Bauer, T.M.2    Daniel, V.3
  • 20
    • 0033152760 scopus 로고    scopus 로고
    • Proteasome inhibitors: A novel class of potent and effective antitumor agents
    • Adams J, Palombella VJ, Sausville EA et al. Proteasome inhibitors: A novel class of potent and effective antitumor agents. Cancer Res 1999;59:2615-2622.
    • (1999) Cancer Res , vol.59 , pp. 2615-2622
    • Adams, J.1    Palombella, V.J.2    Sausville, E.A.3
  • 21
    • 33646421393 scopus 로고    scopus 로고
    • Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of TH1 cytokines
    • Blanco B, Perez-Simon JA, Sanchez-Abarca LI et al. Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of TH1 cytokines. Blood 2006;107:3575-3583.
    • (2006) Blood , vol.107 , pp. 3575-3583
    • Blanco, B.1    Perez-Simon, J.A.2    Sanchez-Abarca, L.I.3
  • 22
    • 33845668472 scopus 로고    scopus 로고
    • Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells
    • Naujokat C, Berges C, Höh A et al. Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells. Immunology 2007;120:120-132.
    • (2007) Immunology , vol.120 , pp. 120-132
    • Naujokat, C.1    Berges, C.2    Höh, A.3
  • 23
    • 33144469102 scopus 로고    scopus 로고
    • The proteasome and proteasome inhibitors in cancer therapy
    • Voorhees PM, Orlowski RZ. The proteasome and proteasome inhibitors in cancer therapy. Annu Rev Pharmacol Toxicol 2006;46:189-213.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 189-213
    • Voorhees, P.M.1    Orlowski, R.Z.2
  • 25
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981;292:154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 26
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 1981;78:7634-7638.
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 27
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 28
    • 0031914244 scopus 로고    scopus 로고
    • Teratocarcinomas and human embryology: Pluripotent human EC cell lines
    • Andrews PW. Teratocarcinomas and human embryology: Pluripotent human EC cell lines. APMIS 1998;106:158-167.
    • (1998) APMIS , vol.106 , pp. 158-167
    • Andrews, P.W.1
  • 29
    • 0345547430 scopus 로고    scopus 로고
    • Potential of embryonic and adult stem cells in vitro
    • Czyz J, Wiese C, Rolletschek A et al. Potential of embryonic and adult stem cells in vitro. Biol Chem 2003;384:1391-1409.
    • (2003) Biol Chem , vol.384 , pp. 1391-1409
    • Czyz, J.1    Wiese, C.2    Rolletschek, A.3
  • 30
    • 2542469858 scopus 로고    scopus 로고
    • Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
    • Xu HM, Liao B, Zhang QJ et al. Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination. J Biol Chem 2004;279:23495-23503.
    • (2004) J Biol Chem , vol.279 , pp. 23495-23503
    • Xu, H.M.1    Liao, B.2    Zhang, Q.J.3
  • 31
    • 33846114807 scopus 로고    scopus 로고
    • SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells
    • Park SW, Hu X, Gupta P et al. SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells. Nat Struct Mol Biol 2007;14:68-75.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 68-75
    • Park, S.W.1    Hu, X.2    Gupta, P.3
  • 32
    • 33846917472 scopus 로고    scopus 로고
    • Analysis of oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
    • Babaie Y, Herwig R, Greber B et al. Analysis of oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. STEM CELLS 2007;25:500-510.
    • (2007) STEM CELLS , vol.25 , pp. 500-510
    • Babaie, Y.1    Herwig, R.2    Greber, B.3
  • 33
    • 33745725870 scopus 로고    scopus 로고
    • Proteomic signature of human embryonic stem cells
    • Baharvand H, Hajheidari M, Ashtiani SK et al. Proteomic signature of human embryonic stem cells. Proteomics 2006;6:3544-3549.
    • (2006) Proteomics , vol.6 , pp. 3544-3549
    • Baharvand, H.1    Hajheidari, M.2    Ashtiani, S.K.3
  • 34
    • 33646744719 scopus 로고    scopus 로고
    • Elimination of damaged proteins during differentiation of embryonic stem cells
    • Hernebring M, Brolen G, Aguilaniu H et al. Elimination of damaged proteins during differentiation of embryonic stem cells. Proc Natl Acad Sci U S A 2006;103:7700-7705.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7700-7705
    • Hernebring, M.1    Brolen, G.2    Aguilaniu, H.3
  • 35
    • 0037335034 scopus 로고    scopus 로고
    • How the ubiquitin-proteasome system controls transcription
    • Muratani M, Tansey WP. How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol 2003;4:192-201.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 192-201
    • Muratani, M.1    Tansey, W.P.2
  • 36
    • 33646872978 scopus 로고    scopus 로고
    • Chromatin signatures of pluripotent cell lines
    • Azuara V, Perry P, Sauer S et al. Chromatin signatures of pluripotent cell lines. Nat Cell Biol 2006;8:532-538.
    • (2006) Nat Cell Biol , vol.8 , pp. 532-538
    • Azuara, V.1    Perry, P.2    Sauer, S.3
  • 37
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006;125:315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3
  • 38
    • 33845645536 scopus 로고    scopus 로고
    • The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells
    • Szutorisz H, Georgiou A, Tora L et al. The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells. Cell 2006;127:1375-1388.
    • (2006) Cell , vol.127 , pp. 1375-1388
    • Szutorisz, H.1    Georgiou, A.2    Tora, L.3
  • 39
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 2006;441:349-353.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3
  • 40
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006;125:301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3
  • 41
    • 7244234099 scopus 로고    scopus 로고
    • Role of histone H2A ubiquitination in Polycomb silencing
    • Wang H, Wang L, Erdjument-Bromage H et al. Role of histone H2A ubiquitination in Polycomb silencing. Nature 2004;431:873-878.
    • (2004) Nature , vol.431 , pp. 873-878
    • Wang, H.1    Wang, L.2    Erdjument-Bromage, H.3
  • 42
    • 7744228427 scopus 로고    scopus 로고
    • Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
    • de Napoles M, Mermoud JE, Wakao R et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell 2004;7:663-676.
    • (2004) Dev Cell , vol.7 , pp. 663-676
    • de Napoles, M.1    Mermoud, J.E.2    Wakao, R.3
  • 43
    • 29144487990 scopus 로고    scopus 로고
    • Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
    • Cao R, Tsukada Y, Zhang Y. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell 2005;20:845-854.
    • (2005) Mol Cell , vol.20 , pp. 845-854
    • Cao, R.1    Tsukada, Y.2    Zhang, Y.3
  • 45
    • 33748437829 scopus 로고    scopus 로고
    • Hematopoietic stem cell self-renewal
    • Akala OO, Clarke MF. Hematopoietic stem cell self-renewal. Curr Opin Genet Dev 2006;16:496-501.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 496-501
    • Akala, O.O.1    Clarke, M.F.2
  • 46
    • 33751515474 scopus 로고    scopus 로고
    • The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity
    • Ben-Saadon R, Zaaroor D, Ziv T et al. The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity. Mol Cell 2006;24:701-711.
    • (2006) Mol Cell , vol.24 , pp. 701-711
    • Ben-Saadon, R.1    Zaaroor, D.2    Ziv, T.3
  • 47
    • 34547893850 scopus 로고    scopus 로고
    • A cDNA-based random RNAi library for functional genetic screens in embryonic stem cells
    • Jian R, Cheng X, Jiang J et al. A cDNA-based random RNAi library for functional genetic screens in embryonic stem cells. STEM CELLS 2007;25:1904-1912.
    • (2007) STEM CELLS , vol.25 , pp. 1904-1912
    • Jian, R.1    Cheng, X.2    Jiang, J.3
  • 48
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams RL, Hilton DJ, Pease S et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 1988;336:684-687.
    • (1988) Nature , vol.336 , pp. 684-687
    • Williams, R.L.1    Hilton, D.J.2    Pease, S.3
  • 49
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L, Yuan X, Sharkis SJ. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. STEM CELLS 2006;24:1476-1486.
    • (2006) STEM CELLS , vol.24 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 50
    • 28444438841 scopus 로고    scopus 로고
    • Defining the role of Wnt/betacatenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells
    • Dravid G, Ye Z, Hammond H et al. Defining the role of Wnt/betacatenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. STEM CELLS 2005;23:1489-1501.
    • (2005) STEM CELLS , vol.23 , pp. 1489-1501
    • Dravid, G.1    Ye, Z.2    Hammond, H.3
  • 51
    • 33744746323 scopus 로고    scopus 로고
    • Basic fibroblast growth factor support of human embryonic stem cell self-renewal
    • Levenstein ME, Ludwig TE, Xu RH et al. Basic fibroblast growth factor support of human embryonic stem cell self-renewal. STEM CELLS 2006;24:568-574.
    • (2006) STEM CELLS , vol.24 , pp. 568-574
    • Levenstein, M.E.1    Ludwig, T.E.2    Xu, R.H.3
  • 52
    • 0034655577 scopus 로고    scopus 로고
    • Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: Possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells
    • Daino H, Matsumura I, Takada K et al. Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: Possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells. Blood 2000;95:2577-2585.
    • (2000) Blood , vol.95 , pp. 2577-2585
    • Daino, H.1    Matsumura, I.2    Takada, K.3
  • 53
    • 10644271682 scopus 로고    scopus 로고
    • TMF/ARA160 is a BC-boxcontaining protein that mediates the degradation of Stat3
    • Perry E, Tsruya R, Levitsky P et al. TMF/ARA160 is a BC-boxcontaining protein that mediates the degradation of Stat3. Oncogene 2004;23:8908-8919.
    • (2004) Oncogene , vol.23 , pp. 8908-8919
    • Perry, E.1    Tsruya, R.2    Levitsky, P.3
  • 54
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004;20:781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 55
    • 0037154292 scopus 로고    scopus 로고
    • Protein degradation: Four E3s for the notch pathway
    • Lai EC. Protein degradation: Four E3s for the notch pathway. Curr Biol 2002;12:R74-R78.
    • (2002) Curr Biol , vol.12
    • Lai, E.C.1
  • 56
    • 17744412856 scopus 로고    scopus 로고
    • The 26S proteasome system in the signaling pathways of TGF-beta superfamily
    • Wang T. The 26S proteasome system in the signaling pathways of TGF-beta superfamily. Front Biosci 2003;8:d1109-d1127.
    • (2003) Front Biosci , vol.8
    • Wang, T.1
  • 57
    • 33947280935 scopus 로고    scopus 로고
    • Arkadia enhances nodal/TGF-beta signaling by coupling phospho-smad2/3 activity and turnover
    • Mavrakis KJ, Andrew RL, Lee KL et al. Arkadia enhances nodal/TGF-beta signaling by coupling phospho-smad2/3 activity and turnover. PLoS Biol 2007;5:e67.
    • (2007) PLoS Biol , vol.5
    • Mavrakis, K.J.1    Andrew, R.L.2    Lee, K.L.3
  • 58
    • 33748138585 scopus 로고    scopus 로고
    • Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
    • Hann SR. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function. Semin Cancer Biol 2006;16:288-302.
    • (2006) Semin Cancer Biol , vol.16 , pp. 288-302
    • Hann, S.R.1
  • 59
    • 0033992481 scopus 로고    scopus 로고
    • The Yin-Yang of TCF/beta-catenin signaling
    • Barker N, Morin PJ, Clevers H. The Yin-Yang of TCF/beta-catenin signaling. Adv Cancer Res 2000;77:1-24.
    • (2000) Adv Cancer Res , vol.77 , pp. 1-24
    • Barker, N.1    Morin, P.J.2    Clevers, H.3
  • 60
    • 0033534379 scopus 로고    scopus 로고
    • Identification of a neural stem cell in the adult mammalian central nervous system
    • Johansson CB, Momma S, Clarke DL et al. Identification of a neural stem cell in the adult mammalian central nervous system. Cell 1999;96:25-34.
    • (1999) Cell , vol.96 , pp. 25-34
    • Johansson, C.B.1    Momma, S.2    Clarke, D.L.3
  • 61
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F, Caillé I, Lim DA et al. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999;97:703-716.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caillé, I.2    Lim, D.A.3
  • 62
    • 0033152378 scopus 로고    scopus 로고
    • Adult mammalian forebrain ependymal and subependymal cells demonstrate proliferative potential, but only subependymal cells have neural stem cell characteristics
    • Chiasson BJ, Tropepe V, Morshead CM et al. Adult mammalian forebrain ependymal and subependymal cells demonstrate proliferative potential, but only subependymal cells have neural stem cell characteristics. J Neurosci 1999;19:4462-4471.
    • (1999) J Neurosci , vol.19 , pp. 4462-4471
    • Chiasson, B.J.1    Tropepe, V.2    Morshead, C.M.3
  • 63
    • 1442354188 scopus 로고    scopus 로고
    • Unique astrocyte ribbon in adult human brain contains neural stem cells but lack chain migration
    • Sanai N, Tramontin AD, Quinones-Hinojosa A et al. Unique astrocyte ribbon in adult human brain contains neural stem cells but lack chain migration. Nature 2004;427:740-744.
    • (2004) Nature , vol.427 , pp. 740-744
    • Sanai, N.1    Tramontin, A.D.2    Quinones-Hinojosa, A.3
  • 64
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage FH. Mammalian neural stem cells. Science 2000;287:1433-1438.
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 66
    • 1542268981 scopus 로고    scopus 로고
    • For the long run: Maintaining germinal niches in the adult brain
    • Alvarez-Buylla A, Lim DA. For the long run: Maintaining germinal niches in the adult brain. Neuron 2004;41:683-686.
    • (2004) Neuron , vol.41 , pp. 683-686
    • Alvarez-Buylla, A.1    Lim, D.A.2
  • 67
    • 29144483551 scopus 로고    scopus 로고
    • Cellular composition of the adult human subventricular zone: A niche of neural stem cells
    • Quinones-Hinojosa A, Sanai N, Soriano-Navarro M et al. Cellular composition of the adult human subventricular zone: A niche of neural stem cells. J Comp Neurol 2006;494:415-434.
    • (2006) J Comp Neurol , vol.494 , pp. 415-434
    • Quinones-Hinojosa, A.1    Sanai, N.2    Soriano-Navarro, M.3
  • 68
    • 0030438734 scopus 로고    scopus 로고
    • The adult rat hippocampus contains primordial neural stem cells
    • Palmer TD, Takahashi H, Gage FH. The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci 1997;8:389-404.
    • (1997) Mol Cell Neurosci , vol.8 , pp. 389-404
    • Palmer, T.D.1    Takahashi, H.2    Gage, F.H.3
  • 69
    • 0031928119 scopus 로고    scopus 로고
    • Multipotent progenitor cells in the adult dentate gyrus
    • Gage FH, Kempermann G, Palmer TD et al. Multipotent progenitor cells in the adult dentate gyrus. J Neurobiol 1998;36:249-266.
    • (1998) J Neurobiol , vol.36 , pp. 249-266
    • Gage, F.H.1    Kempermann, G.2    Palmer, T.D.3
  • 70
    • 0033545920 scopus 로고    scopus 로고
    • Continuation of neurogenesis in the hippocampus of the adult macaque
    • Kornack DR, Rakic P. Continuation of neurogenesis in the hippocampus of the adult macaque. Proc Natl Acad Sci U S A 1999;96:5768-5773.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5768-5773
    • Kornack, D.R.1    Rakic, P.2
  • 71
    • 0036522968 scopus 로고    scopus 로고
    • Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains progenitors
    • Seaberg RM, van der Kooy D. Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains progenitors. J Neurosci 2002;22:1784-1793.
    • (2002) J Neurosci , vol.22 , pp. 1784-1793
    • Seaberg, R.M.1    van der Kooy, D.2
  • 72
    • 9144260594 scopus 로고    scopus 로고
    • A novel secretory factor, neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus
    • Ueki T, Tanaka M, Yamashita K et al. A novel secretory factor, neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus. J Neurosci 2003;23:11732-11740.
    • (2003) J Neurosci , vol.23 , pp. 11732-11740
    • Ueki, T.1    Tanaka, M.2    Yamashita, K.3
  • 73
    • 4644292370 scopus 로고    scopus 로고
    • Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus
    • Seri B, Garcia-Verdugo JM, Collado-Morente L et al. Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus. J Comp Neurol 2004;478:359-378.
    • (2004) J Comp Neurol , vol.478 , pp. 359-378
    • Seri, B.1    Garcia-Verdugo, J.M.2    Collado-Morente, L.3
  • 74
    • 32144442520 scopus 로고    scopus 로고
    • Cell proliferation in the adult hippocampal formation of rodents and its modulation by entorhinal and fimbria-fornix afferents
    • Fontana X, Nacher J, Soriano E et al. Cell proliferation in the adult hippocampal formation of rodents and its modulation by entorhinal and fimbria-fornix afferents. Cereb Cortex 2006;16:301-312.
    • (2006) Cereb Cortex , vol.16 , pp. 301-312
    • Fontana, X.1    Nacher, J.2    Soriano, E.3
  • 75
    • 33746580678 scopus 로고    scopus 로고
    • Mesodermal cell types induce neurogenesis from adult human hippocampal progenitor cells
    • Hermann A, Maisel M, Liebau S et al. Mesodermal cell types induce neurogenesis from adult human hippocampal progenitor cells. J Neurochem 2006;98:629-640.
    • (2006) J Neurochem , vol.98 , pp. 629-640
    • Hermann, A.1    Maisel, M.2    Liebau, S.3
  • 76
    • 33746851247 scopus 로고    scopus 로고
    • Composition and organization of the SCZ: A large germinal layer containing neural stem cells in the adult mammalian brain
    • Seri B, Herrera DG, Gritti A et al. Composition and organization of the SCZ: A large germinal layer containing neural stem cells in the adult mammalian brain. Cereb Cortex 2006;16(suppl 1):i103-i111.
    • (2006) Cereb Cortex , vol.16 , Issue.SUPPL. 1
    • Seri, B.1    Herrera, D.G.2    Gritti, A.3
  • 77
    • 33745509468 scopus 로고    scopus 로고
    • Multipotent neural stem cells from the adult tegmentum with dopaminergic potential develop essential properties of functional neurons
    • Hermann A, Maisel M, Wegner F et la. Multipotent neural stem cells from the adult tegmentum with dopaminergic potential develop essential properties of functional neurons. STEM CELLS 2006;24:949-964.
    • (2006) STEM CELLS , vol.24 , pp. 949-964
    • Hermann, A.1    Maisel, M.2    Wegner, F.3    la4
  • 78
    • 1842527386 scopus 로고    scopus 로고
    • Radial glia serve as neuronal progenitors in all regions of the central nervous system
    • Anthony TE, Klein C, Fishell G et al. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron 2004;41:881-890.
    • (2004) Neuron , vol.41 , pp. 881-890
    • Anthony, T.E.1    Klein, C.2    Fishell, G.3
  • 79
    • 10644232285 scopus 로고    scopus 로고
    • Radial glia give rise to adult neural stem cells in the subventricualr zone
    • Merkle FT, Tramontin AD, Garcia-Verdugo JM et al. Radial glia give rise to adult neural stem cells in the subventricualr zone. Proc Natl Acad Sci U S A 2004;101:17528-17532.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17528-17532
    • Merkle, F.T.1    Tramontin, A.D.2    Garcia-Verdugo, J.M.3
  • 81
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992;255:1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 82
    • 0027491410 scopus 로고
    • bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
    • Vescovi AL, Reynolds BA, Fraser DD et al. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 1993;11:951-966.
    • (1993) Neuron , vol.11 , pp. 951-966
    • Vescovi, A.L.1    Reynolds, B.A.2    Fraser, D.D.3
  • 83
    • 0029610078 scopus 로고
    • Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain
    • Gage FH, Coates OW, Palmer RD et al. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci U S A 1995;92:11879-11883.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11879-11883
    • Gage, F.H.1    Coates, O.W.2    Palmer, R.D.3
  • 84
    • 0011733093 scopus 로고
    • Pluripotential hemopoietic stem cells in adult mouse brain
    • Bartlett PF. Pluripotential hemopoietic stem cells in adult mouse brain. Proc Natl Acad Sci U S A 1982;79:2722-2725.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 2722-2725
    • Bartlett, P.F.1
  • 85
    • 0033593654 scopus 로고    scopus 로고
    • Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
    • Bjornson CRR, Rietze RL, Reynolds BA et al. Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999;283:534-537.
    • (1999) Science , vol.283 , pp. 534-537
    • Bjornson, C.R.R.1    Rietze, R.L.2    Reynolds, B.A.3
  • 86
    • 0035889138 scopus 로고    scopus 로고
    • Identification of a candidate human neurohematopoietic stem-cell population
    • Shih CC, Weng Y, Mamelak A et al. Identification of a candidate human neurohematopoietic stem-cell population. Blood 2001;98:2412-2422.
    • (2001) Blood , vol.98 , pp. 2412-2422
    • Shih, C.C.1    Weng, Y.2    Mamelak, A.3
  • 87
    • 0033804048 scopus 로고    scopus 로고
    • Skeletal myogenic potential of human and mouse neural stem cells
    • Galli R, Borello U, Gritti A et al. Skeletal myogenic potential of human and mouse neural stem cells. Nat Neurosci 2000;3:986-991.
    • (2000) Nat Neurosci , vol.3 , pp. 986-991
    • Galli, R.1    Borello, U.2    Gritti, A.3
  • 88
    • 0035899505 scopus 로고    scopus 로고
    • Purification of a pluripotent neural stem cell from the adult mouse brain
    • Rietze RL, Valcanis H, Brooker GF et al. Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 2001;412:736-739.
    • (2001) Nature , vol.412 , pp. 736-739
    • Rietze, R.L.1    Valcanis, H.2    Brooker, G.F.3
  • 89
    • 0034595855 scopus 로고    scopus 로고
    • Generalized potential of neural stem cells
    • Clarke DL, Johansson CB, Wilbertz J et al. Generalized potential of neural stem cells. Science 2000;288:1660-1663.
    • (2000) Science , vol.288 , pp. 1660-1663
    • Clarke, D.L.1    Johansson, C.B.2    Wilbertz, J.3
  • 90
    • 0027461752 scopus 로고
    • Cloning and growth of multipotential neural precursors-requirements for proliferation and differentiation
    • Kilpatrick TJ, Bartlett PF. Cloning and growth of multipotential neural precursors-requirements for proliferation and differentiation. Neuron 1993;10:255-265.
    • (1993) Neuron , vol.10 , pp. 255-265
    • Kilpatrick, T.J.1    Bartlett, P.F.2
  • 91
    • 0027941902 scopus 로고
    • A self-renewing multipotential stem cell in embryonic rat cerebral cortex
    • Davis AA, Temple S. A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature 1994;372:263-266.
    • (1994) Nature , vol.372 , pp. 263-266
    • Davis, A.A.1    Temple, S.2
  • 92
    • 0031012594 scopus 로고    scopus 로고
    • In vitro propagation and inducible differentiation of multipotent progenitor cells from human fetal brain
    • Chalmers-Redman RM, Priestly T, Kemp JA et al. In vitro propagation and inducible differentiation of multipotent progenitor cells from human fetal brain. Neuroscience 1997;76:1121-1128.
    • (1997) Neuroscience , vol.76 , pp. 1121-1128
    • Chalmers-Redman, R.M.1    Priestly, T.2    Kemp, J.A.3
  • 93
    • 0032837298 scopus 로고    scopus 로고
    • In vitro expansion of a multipotent population of human neural progenitor cells
    • Carpenter MK, Cui X, Hu ZY et al. In vitro expansion of a multipotent population of human neural progenitor cells. Exp Neurol 1999;158:265-278.
    • (1999) Exp Neurol , vol.158 , pp. 265-278
    • Carpenter, M.K.1    Cui, X.2    Hu, Z.Y.3
  • 94
    • 0034687840 scopus 로고    scopus 로고
    • Direct isolation of human central nervous system stem cells
    • Uchida N, Buck DW, He D et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A 2000;97:14720-14725.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 14720-14725
    • Uchida, N.1    Buck, D.W.2    He, D.3
  • 95
    • 0023752757 scopus 로고
    • Cell lineage analysis reveals multipotency of some avian neural crest cells
    • Bronner-Fraser M, Fraser S. Cell lineage analysis reveals multipotency of some avian neural crest cells. Nature 1988;335:161-164.
    • (1988) Nature , vol.335 , pp. 161-164
    • Bronner-Fraser, M.1    Fraser, S.2
  • 96
    • 0025854306 scopus 로고
    • Common precursors for neural and mesenchymal derivatives in the cephalic neural crest
    • Baroffio A, Dupin E, Le Duarin N. Common precursors for neural and mesenchymal derivatives in the cephalic neural crest. Development 1991;112:301-305.
    • (1991) Development , vol.112 , pp. 301-305
    • Baroffio, A.1    Dupin, E.2    Le Duarin, N.3
  • 97
    • 0026497015 scopus 로고
    • Isolation of a stem cell for neurons and glia from the mammalian neural crest
    • Stemple DL, Anderson DJ. Isolation of a stem cell for neurons and glia from the mammalian neural crest. Cell 1992;71:973-985.
    • (1992) Cell , vol.71 , pp. 973-985
    • Stemple, D.L.1    Anderson, D.J.2
  • 98
    • 0033525587 scopus 로고    scopus 로고
    • Prospective identification of, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells
    • Morrison SJ, White PM, Zock C et al. Prospective identification of, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells. Cell 1999;96:737-749.
    • (1999) Cell , vol.96 , pp. 737-749
    • Morrison, S.J.1    White, P.M.2    Zock, C.3
  • 100
    • 0037238008 scopus 로고    scopus 로고
    • Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by delta
    • Itoh M, Kim CH, Palardy G et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by delta. Dev Cell 2003;4:67-82.
    • (2003) Dev Cell , vol.4 , pp. 67-82
    • Itoh, M.1    Kim, C.H.2    Palardy, G.3
  • 101
    • 31444447881 scopus 로고    scopus 로고
    • Notch signaling in vertebrate neural development
    • Louvi A, Artavanis-Tsakonas S. Notch signaling in vertebrate neural development. Nat Rev Neurosci 2006;7:93-102.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 93-102
    • Louvi, A.1    Artavanis-Tsakonas, S.2
  • 102
    • 24344441942 scopus 로고    scopus 로고
    • Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling
    • Barsi JC, Rajendra R, Wu JI et al. Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech Dev 2005;122:1106-1117.
    • (2005) Mech Dev , vol.122 , pp. 1106-1117
    • Barsi, J.C.1    Rajendra, R.2    Wu, J.I.3
  • 103
    • 24344481807 scopus 로고    scopus 로고
    • Mind bomb 1 is essential for generating functional Notch ligands to activate Notch
    • Koo BK, Lim HS, Song R et al. Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development 2005;132:3459-3470.
    • (2005) Development , vol.132 , pp. 3459-3470
    • Koo, B.K.1    Lim, H.S.2    Song, R.3
  • 104
    • 23344452833 scopus 로고    scopus 로고
    • A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize Ndegrons
    • Tasaki T, Mulder LC, Iwamatsu A et al. A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize Ndegrons. Mol Cell Biol 2005;25:7120-7136.
    • (2005) Mol Cell Biol , vol.25 , pp. 7120-7136
    • Tasaki, T.1    Mulder, L.C.2    Iwamatsu, A.3
  • 105
    • 33746211620 scopus 로고    scopus 로고
    • Impact of the N-terminal amino acid on targeted protein degradation
    • Meinnel T, Serero A, Giglione C. Impact of the N-terminal amino acid on targeted protein degradation. Biol Chem 2006;387:839-851.
    • (2006) Biol Chem , vol.387 , pp. 839-851
    • Meinnel, T.1    Serero, A.2    Giglione, C.3
  • 106
    • 33646573377 scopus 로고    scopus 로고
    • Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway
    • An JY, Seo JW, Tasaki T et al. Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proc Natl Acad Sci U S A 2006;103:6212-6217.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6212-6217
    • An, J.Y.1    Seo, J.W.2    Tasaki, T.3
  • 107
    • 0037509859 scopus 로고    scopus 로고
    • The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
    • Groisman R, Polanowska J, Kuraoka I et al. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 2003;113:357-367.
    • (2003) Cell , vol.113 , pp. 357-367
    • Groisman, R.1    Polanowska, J.2    Kuraoka, I.3
  • 108
    • 33749535905 scopus 로고    scopus 로고
    • Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery
    • Angers S, Li T, Yi X et al. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature 2006;443:590-593.
    • (2006) Nature , vol.443 , pp. 590-593
    • Angers, S.1    Li, T.2    Yi, X.3
  • 109
    • 33645216339 scopus 로고    scopus 로고
    • Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome
    • Bondar T, Kalinina A, Khair L et al. Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome. Mol Cell Biol 2006;26:2531-2539.
    • (2006) Mol Cell Biol , vol.26 , pp. 2531-2539
    • Bondar, T.1    Kalinina, A.2    Khair, L.3
  • 110
    • 33751331884 scopus 로고    scopus 로고
    • Deletion of DDB1 in mouse brain and lens lead to p53-dependent elimination of proliferating cells
    • Cang Y, Zhang J, Nicholas SA et al. Deletion of DDB1 in mouse brain and lens lead to p53-dependent elimination of proliferating cells. Cell 2006;127:929-940.
    • (2006) Cell , vol.127 , pp. 929-940
    • Cang, Y.1    Zhang, J.2    Nicholas, S.A.3
  • 111
    • 31644448703 scopus 로고    scopus 로고
    • Ubiquitin C-terminal hydrolase L1 regulates the morphology of neural progenitor cells and modulates their differentiation
    • Sakurai M, Ayukawa K, Setsuie R et al. Ubiquitin C-terminal hydrolase L1 regulates the morphology of neural progenitor cells and modulates their differentiation. J Cell Sci 2006;119:162-171.
    • (2006) J Cell Sci , vol.119 , pp. 162-171
    • Sakurai, M.1    Ayukawa, K.2    Setsuie, R.3
  • 112
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
    • Liu Y, Fallon L, Lashuel HA et al. The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell 2002;111:209-218.
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3
  • 113
    • 10744224825 scopus 로고    scopus 로고
    • Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron
    • Osaka H, Wang YL, Takada S et al. Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron. Hum Mol Genet 2003;12:1945-1958.
    • (2003) Hum Mol Genet , vol.12 , pp. 1945-1958
    • Osaka, H.1    Wang, Y.L.2    Takada, S.3
  • 114
    • 0034680909 scopus 로고    scopus 로고
    • Recognition and ubiquitination of Notch by Itch, a Hect-type E3 ubiquitin ligase
    • Qiu L, Joazeiro C, Fang N et al. Recognition and ubiquitination of Notch by Itch, a Hect-type E3 ubiquitin ligase. J Biol Chem 2000;275:35734-35737.
    • (2000) J Biol Chem , vol.275 , pp. 35734-35737
    • Qiu, L.1    Joazeiro, C.2    Fang, N.3
  • 115
    • 0035929669 scopus 로고    scopus 로고
    • The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
    • Oberg C, Li J, Pauley A et al. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J Biol Chem 2001;276:35847-35853.
    • (2001) J Biol Chem , vol.276 , pp. 35847-35853
    • Oberg, C.1    Li, J.2    Pauley, A.3
  • 116
    • 0034791336 scopus 로고    scopus 로고
    • SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
    • Wu G, Lyapina S, Das I et al. SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol Cell Biol 2001;21:7403-7415.
    • (2001) Mol Cell Biol , vol.21 , pp. 7403-7415
    • Wu, G.1    Lyapina, S.2    Das, I.3
  • 117
    • 0037663379 scopus 로고    scopus 로고
    • Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
    • McGill MA, McGlade CJ. Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J Biol Chem 2003;278:23196-23203.
    • (2003) J Biol Chem , vol.278 , pp. 23196-23203
    • McGill, M.A.1    McGlade, C.J.2
  • 118
    • 0035651380 scopus 로고    scopus 로고
    • Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta
    • Lai EC, Deblandre GA, Kintner C et al. Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta. Dev Cell 2001;1:783-794.
    • (2001) Dev Cell , vol.1 , pp. 783-794
    • Lai, E.C.1    Deblandre, G.A.2    Kintner, C.3
  • 119
    • 18844429102 scopus 로고    scopus 로고
    • The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta
    • Lai EC, Roegiers F, Qin X et al. The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 2005;132:2319-2332.
    • (2005) Development , vol.132 , pp. 2319-2332
    • Lai, E.C.1    Roegiers, F.2    Qin, X.3
  • 120
    • 33845980603 scopus 로고    scopus 로고
    • Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1
    • Song R, Koo BK, Yoon KJ et al. Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1. J Biol Chem 2006;281:36391-36400.
    • (2006) J Biol Chem , vol.281 , pp. 36391-36400
    • Song, R.1    Koo, B.K.2    Yoon, K.J.3
  • 121
    • 0037080811 scopus 로고    scopus 로고
    • LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation
    • Nie J, McGill MA, Dermer M et al. LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation. EMBO J 2002;21:93-102.
    • (2002) EMBO J , vol.21 , pp. 93-102
    • Nie, J.1    McGill, M.A.2    Dermer, M.3
  • 122
    • 33845401909 scopus 로고    scopus 로고
    • Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche
    • Kuo CT, Mirzadeh Z, Soriano-Navarro M et al. Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell 2006;127:1253-1264.
    • (2006) Cell , vol.127 , pp. 1253-1264
    • Kuo, C.T.1    Mirzadeh, Z.2    Soriano-Navarro, M.3
  • 123
    • 0344197741 scopus 로고    scopus 로고
    • Regulation of protein tyrosine kinase signalling by substrate degradation during brain development
    • Arnaud L, Ballif BA, Cooper JA. Regulation of protein tyrosine kinase signalling by substrate degradation during brain development. Mol Cell Biol 2003;23:9293-9302.
    • (2003) Mol Cell Biol , vol.23 , pp. 9293-9302
    • Arnaud, L.1    Ballif, B.A.2    Cooper, J.A.3
  • 124
    • 4043068564 scopus 로고    scopus 로고
    • Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1
    • Bock HH, Jossin Y, May P et al. Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. J Biol Chem 2004;279:33471-33479.
    • (2004) J Biol Chem , vol.279 , pp. 33471-33479
    • Bock, H.H.1    Jossin, Y.2    May, P.3
  • 125
    • 0032508698 scopus 로고    scopus 로고
    • p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway
    • Patrick GN, Zhou P, Kwon YT et al. p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. J Biol Chem 1998;273:24057-24064.
    • (1998) J Biol Chem , vol.273 , pp. 24057-24064
    • Patrick, G.N.1    Zhou, P.2    Kwon, Y.T.3
  • 126
    • 0037442786 scopus 로고    scopus 로고
    • Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation
    • Saito T, Onuki R, Fujita Y et al. Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation. J Neurosci 2003;23:1189-1197.
    • (2003) J Neurosci , vol.23 , pp. 1189-1197
    • Saito, T.1    Onuki, R.2    Fujita, Y.3
  • 127
    • 3042776499 scopus 로고    scopus 로고
    • Nestin expression is lost in a neural stem cell line through a mechanism involving the proteasome and Notch signalling
    • Mellodew K, Suhr R, Uwanogho DA et al. Nestin expression is lost in a neural stem cell line through a mechanism involving the proteasome and Notch signalling. Brain Res Dev Brain Res 2004;151:13-23.
    • (2004) Brain Res Dev Brain Res , vol.151 , pp. 13-23
    • Mellodew, K.1    Suhr, R.2    Uwanogho, D.A.3
  • 128
    • 33750439078 scopus 로고    scopus 로고
    • The journey of developing hematopoietic cells
    • Mikkola HKA, Orkin SH. The journey of developing hematopoietic cells. Development 2006;133:3733-3744.
    • (2006) Development , vol.133 , pp. 3733-3744
    • Mikkola, H.K.A.1    Orkin, S.H.2
  • 129
    • 34247896991 scopus 로고    scopus 로고
    • Ontogeny of the hematopoietic system
    • Cumano A, Godin I. Ontogeny of the hematopoietic system. Annu Rev Immunol 2007;25:745-785.
    • (2007) Annu Rev Immunol , vol.25 , pp. 745-785
    • Cumano, A.1    Godin, I.2
  • 130
    • 0014744817 scopus 로고
    • Ontogeny of the haematopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo
    • Moore MA, Metcalf D. Ontogeny of the haematopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. Br J Haematol 1970;18:279-296.
    • (1970) Br J Haematol , vol.18 , pp. 279-296
    • Moore, M.A.1    Metcalf, D.2
  • 131
    • 0026343035 scopus 로고
    • In vitro development of murine T cells from prethymic and preliver embryonic yolk sac hematopoietic stem cells
    • Liu CP, Auerbach R. In vitro development of murine T cells from prethymic and preliver embryonic yolk sac hematopoietic stem cells. Development 1991;113:1315-1323.
    • (1991) Development , vol.113 , pp. 1315-1323
    • Liu, C.P.1    Auerbach, R.2
  • 132
    • 0030879733 scopus 로고    scopus 로고
    • Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac
    • Yoder MC, Hiatt K, Dutt P et al. Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 1997;7:335-344.
    • (1997) Immunity , vol.7 , pp. 335-344
    • Yoder, M.C.1    Hiatt, K.2    Dutt, P.3
  • 133
    • 0027178567 scopus 로고
    • An early pre-liver intraembryonic source of CFU-S in the developing mouse
    • Medvinsky AL, Samoylina NL, Muller AM et al. An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature 1993;364:64-67.
    • (1993) Nature , vol.364 , pp. 64-67
    • Medvinsky, A.L.1    Samoylina, N.L.2    Muller, A.M.3
  • 134
    • 0028467947 scopus 로고
    • Development of hematopoietic stem cell activity in the mouse embryo
    • Müller AM, Medvinsky A, Strouboulis J et al. Development of hematopoietic stem cell activity in the mouse embryo. Immunity 1994;1:291-301.
    • (1994) Immunity , vol.1 , pp. 291-301
    • Müller, A.M.1    Medvinsky, A.2    Strouboulis, J.3
  • 135
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996;86:897-906.
    • (1996) Cell , vol.86 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 136
    • 0030051968 scopus 로고    scopus 로고
    • Aorta-associated CD34+ hematopoietic cells in the early human embryo
    • Tavian M, Coulombel L, Luton D et al. Aorta-associated CD34+ hematopoietic cells in the early human embryo. Blood 1996;87:67-72.
    • (1996) Blood , vol.87 , pp. 67-72
    • Tavian, M.1    Coulombel, L.2    Luton, D.3
  • 138
    • 14644416569 scopus 로고    scopus 로고
    • The placenta is a niche for hematopoietic stem cells
    • Gekas C, Dierterlen-Lievre F, Orkin SH et al. The placenta is a niche for hematopoietic stem cells. Dev Cell 2005;8:365-375.
    • (2005) Dev Cell , vol.8 , pp. 365-375
    • Gekas, C.1    Dierterlen-Lievre, F.2    Orkin, S.H.3
  • 139
    • 14644437071 scopus 로고    scopus 로고
    • The murine placenta contains hematopoietic stem cells within the vascular labyrinth region
    • Ottersbach K, Dzierzak E. The murine placenta contains hematopoietic stem cells within the vascular labyrinth region. Dev Cell 2005;8:377-387.
    • (2005) Dev Cell , vol.8 , pp. 377-387
    • Ottersbach, K.1    Dzierzak, E.2
  • 140
    • 0030483541 scopus 로고    scopus 로고
    • Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo
    • Sanchez MJ, Holmes A, Miles C et al. Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo. Immunity 1996;5:513-525.
    • (1996) Immunity , vol.5 , pp. 513-525
    • Sanchez, M.J.1    Holmes, A.2    Miles, C.3
  • 141
    • 0035836658 scopus 로고    scopus 로고
    • Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis
    • Palis J, Chan RJ, Koniski A et al. Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis. Proc Natl Acad Sci U S A 2001;98:4528-4533.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4528-4533
    • Palis, J.1    Chan, R.J.2    Koniski, A.3
  • 142
    • 0033526827 scopus 로고    scopus 로고
    • Stem cell emergence and hemopoietic activity are incompatible in mouse intraembryonic sites
    • Godin I, Garcia-Porrero JA, Dieterlen-Lievre F et al. Stem cell emergence and hemopoietic activity are incompatible in mouse intraembryonic sites. J Exp Med 1999;190:43-52.
    • (1999) J Exp Med , vol.190 , pp. 43-52
    • Godin, I.1    Garcia-Porrero, J.A.2    Dieterlen-Lievre, F.3
  • 143
    • 0036754421 scopus 로고    scopus 로고
    • Roles of spleen and liver in development of the murine hematopoietic system
    • Wolber FM, Leonard E, Michael S et al. Roles of spleen and liver in development of the murine hematopoietic system. Exp Hematol 2002;30:1010-1019.
    • (2002) Exp Hematol , vol.30 , pp. 1010-1019
    • Wolber, F.M.1    Leonard, E.2    Michael, S.3
  • 144
    • 0030039864 scopus 로고    scopus 로고
    • Circulation of hematopoietic progenitors in the mouse embryo
    • Delassus S, Cumano A. Circulation of hematopoietic progenitors in the mouse embryo. Immunity 1996;4:97-106.
    • (1996) Immunity , vol.4 , pp. 97-106
    • Delassus, S.1    Cumano, A.2
  • 145
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003;425:836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3
  • 146
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005;121:1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3
  • 147
    • 33845445939 scopus 로고    scopus 로고
    • Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
    • Sugiyama T, Kohara H, Noda M et al. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 2006;25:977-988.
    • (2006) Immunity , vol.25 , pp. 977-988
    • Sugiyama, T.1    Kohara, H.2    Noda, M.3
  • 148
    • 8844251482 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cell growth
    • Attar EC, Scadden DT. Regulation of hematopoietic stem cell growth. Leukemia 2004;18:1760-1768.
    • (2004) Leukemia , vol.18 , pp. 1760-1768
    • Attar, E.C.1    Scadden, D.T.2
  • 149
    • 33644827383 scopus 로고    scopus 로고
    • Bone-marrow haematopoietic stem-cell niches
    • Wilson A, Trumpp A. Bone-marrow haematopoietic stem-cell niches. Nat Rev Immunol 2006;6:93-106.
    • (2006) Nat Rev Immunol , vol.6 , pp. 93-106
    • Wilson, A.1    Trumpp, A.2
  • 150
    • 34247867901 scopus 로고    scopus 로고
    • Immunobiology of allogeneic stem cell transplantation
    • Welniak LA, Blazar BR, Murphy WJ. Immunobiology of allogeneic stem cell transplantation. Annu Rev Immunol 2007;25:139-170.
    • (2007) Annu Rev Immunol , vol.25 , pp. 139-170
    • Welniak, L.A.1    Blazar, B.R.2    Murphy, W.J.3
  • 151
    • 0000062301 scopus 로고
    • Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells
    • Becker A, McCulloch E, Till J. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 1963;197:452-454.
    • (1963) Nature , vol.197 , pp. 452-454
    • Becker, A.1    McCulloch, E.2    Till, J.3
  • 152
    • 0012509065 scopus 로고
    • Haematopoietic stem cells
    • Lewis JP, Trobaugh FE Jr. Haematopoietic stem cells. Nature 1964; 204:589-590.
    • (1964) Nature , vol.204 , pp. 589-590
    • Lewis, J.P.1    Trobaugh Jr., F.E.2
  • 153
    • 0023058277 scopus 로고
    • Isolation of two early B lymphocyte progenitors from mouse marrow: A committed pre-pre-B cell and a clonogenic Thy-1lo hematopoietic stem cell
    • Müller-Sieburg CE, Whitlock CA, Weissman IL. Isolation of two early B lymphocyte progenitors from mouse marrow: A committed pre-pre-B cell and a clonogenic Thy-1lo hematopoietic stem cell. Cell 1986;44:653-662.
    • (1986) Cell , vol.44 , pp. 653-662
    • Müller-Sieburg, C.E.1    Whitlock, C.A.2    Weissman, I.L.3
  • 154
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science 1988;241:58-62.
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 155
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M, Hanada K, Hamada H et al. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996;273:242-245.
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3
  • 156
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997;91:661-672.
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 157
    • 0027176974 scopus 로고
    • Demonstration of a ubiquitin binding site on murine haemopoietic progenitor cells: Implication of ubiquitin in homing and adhesion
    • Parakh KA, Kannan K. Demonstration of a ubiquitin binding site on murine haemopoietic progenitor cells: Implication of ubiquitin in homing and adhesion. Br J Haematol 1993;84:212-218.
    • (1993) Br J Haematol , vol.84 , pp. 212-218
    • Parakh, K.A.1    Kannan, K.2
  • 158
    • 0030583158 scopus 로고    scopus 로고
    • Extracellular ubiquitin regulates the growth of human hematopoietic cells
    • Daino H, Shibayama H, Machii et al. Extracellular ubiquitin regulates the growth of human hematopoietic cells. Biochem Biophys Res Commun 1996;223:226-228.
    • (1996) Biochem Biophys Res Commun , vol.223 , pp. 226-228
    • Daino, H.1    Shibayama, H.2    Machii3
  • 159
    • 0022530971 scopus 로고
    • Homing of a cloned multipotential stem cell line in spleen and intraperitoneal membrane
    • Hardy CL, Kishimoto T, Harjes K et al. Homing of a cloned multipotential stem cell line in spleen and intraperitoneal membrane. Exp Hematol 1986;14:636-642.
    • (1986) Exp Hematol , vol.14 , pp. 636-642
    • Hardy, C.L.1    Kishimoto, T.2    Harjes, K.3
  • 160
    • 3042838749 scopus 로고    scopus 로고
    • A mouse model to study organ homing behaviour of haemopoietic progenitor cells reveals high selectivity but low efficiency of multipotent progenitors to home into haemopoietic organs
    • Henschler R, Fehervizyova Z, Bistrian R et al. A mouse model to study organ homing behaviour of haemopoietic progenitor cells reveals high selectivity but low efficiency of multipotent progenitors to home into haemopoietic organs. Br J Haematol 2004;126:111-119.
    • (2004) Br J Haematol , vol.126 , pp. 111-119
    • Henschler, R.1    Fehervizyova, Z.2    Bistrian, R.3
  • 161
    • 0033623487 scopus 로고    scopus 로고
    • Proteasome inhibitors induce caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells
    • Naujokat C, Sezer O, Zinke H et al. Proteasome inhibitors induce caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells. Eur J Haematol 2000;65:221-236.
    • (2000) Eur J Haematol , vol.65 , pp. 221-236
    • Naujokat, C.1    Sezer, O.2    Zinke, H.3
  • 162
    • 0043164960 scopus 로고    scopus 로고
    • Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion
    • Zavrski I, Naujokat C, Niemöller K et al. Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion. J Cancer Res Clin Oncol 2003;129:383-391.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 383-391
    • Zavrski, I.1    Naujokat, C.2    Niemöller, K.3
  • 163
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukaemia cells
    • Guzman ML, Neering SJ, Upchurch D et al. Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukaemia cells. Blood 2001;98:2301-2307.
    • (2001) Blood , vol.98 , pp. 2301-2307
    • Guzman, M.L.1    Neering, S.J.2    Upchurch, D.3
  • 164
    • 0037059012 scopus 로고    scopus 로고
    • Preferential induction of apoptosis for primary human leukemic stem cells
    • Guzman ML, Swiderski CF, Howard DS et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proc Natl Acad Sci U S A 2002;99:16220-16225.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16220-16225
    • Guzman, M.L.1    Swiderski, C.F.2    Howard, D.S.3
  • 165
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
    • Palombella VJ, Rando OJ, Goldberg AL et al. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 1994;78:773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3
  • 166
    • 0030612937 scopus 로고    scopus 로고
    • Mayo MW, Wang CY, Cogswell PC et al. Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras. Science 1997;278:1812-1815.
    • Mayo MW, Wang CY, Cogswell PC et al. Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras. Science 1997;278:1812-1815.
  • 167
    • 33750432183 scopus 로고    scopus 로고
    • Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression
    • Basseres DS, Baldwin AS. Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression. Oncogene 2006;25:6817-6813.
    • (2006) Oncogene , vol.25 , pp. 6817-6813
    • Basseres, D.S.1    Baldwin, A.S.2
  • 168
    • 0033562798 scopus 로고    scopus 로고
    • An essential role for NF-κB in human CD34+ bone marrow cell survival
    • Pyatt DW, Stillman WS, Yang Y et al. An essential role for NF-κB in human CD34+ bone marrow cell survival. Blood 1999;93:3302-3308.
    • (1999) Blood , vol.93 , pp. 3302-3308
    • Pyatt, D.W.1    Stillman, W.S.2    Yang, Y.3
  • 169
    • 11244280878 scopus 로고    scopus 로고
    • NF-κB family proteins participate in multiple steps of hematopoiesis through elimination of reactive oxygen species
    • Nakata S, Matsumura I, Tanaka H et al. NF-κB family proteins participate in multiple steps of hematopoiesis through elimination of reactive oxygen species. J Biol Chem 2004;279:55578-55586.
    • (2004) J Biol Chem , vol.279 , pp. 55578-55586
    • Nakata, S.1    Matsumura, I.2    Tanaka, H.3
  • 170
    • 0028148227 scopus 로고
    • A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκBα that is still bound to NF-κB
    • Traenckner EB, Wilk S, Baeuerle PA. A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκBα that is still bound to NF-κB. EMBO J 1994;13:5433-5441.
    • (1994) EMBO J , vol.13 , pp. 5433-5441
    • Traenckner, E.B.1    Wilk, S.2    Baeuerle, P.A.3
  • 171
    • 0032567342 scopus 로고    scopus 로고
    • Degradation of proto-oncoprotein c-Rel by the ubiquitin-proteasome pathway
    • Chen E, Hrdlickova R, Nehyba J et al. Degradation of proto-oncoprotein c-Rel by the ubiquitin-proteasome pathway. J Biol Chem 1998;273:35201-35207.
    • (1998) J Biol Chem , vol.273 , pp. 35201-35207
    • Chen, E.1    Hrdlickova, R.2    Nehyba, J.3
  • 172
    • 3142771914 scopus 로고    scopus 로고
    • Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response
    • Saccani S, Marazzi I, Beg AA et al. Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response. J Exp Med 2004;200:107-113.
    • (2004) J Exp Med , vol.200 , pp. 107-113
    • Saccani, S.1    Marazzi, I.2    Beg, A.A.3
  • 173
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Ghosh S. Signaling to NF-κB. Genes Dev 2004;18:2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 174
    • 0032716107 scopus 로고    scopus 로고
    • The combined absence of the transcription factors Rel and RelA leads to multiple hemaopoietic cell defects
    • Grossmann M, Metcalf D, Merryful J et al. The combined absence of the transcription factors Rel and RelA leads to multiple hemaopoietic cell defects. Proc Natl Acad Sci U S A 1999;96:11848-11853.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 11848-11853
    • Grossmann, M.1    Metcalf, D.2    Merryful, J.3
  • 175
    • 33746532476 scopus 로고    scopus 로고
    • Acetylation and MAPK phosphorylation cooperates to regulate the degradation of active GATA-1
    • Hernandez-Hernandez A, Ray P, Litos G et al. Acetylation and MAPK phosphorylation cooperates to regulate the degradation of active GATA-1. EMBO J 2006;25:3264-3274.
    • (2006) EMBO J , vol.25 , pp. 3264-3274
    • Hernandez-Hernandez, A.1    Ray, P.2    Litos, G.3
  • 176
    • 21644438110 scopus 로고    scopus 로고
    • Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation
    • Minegishi N, Suzuki N, Kawatani Y et al. Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation. Genes Cells 2005;10:693-704.
    • (2005) Genes Cells , vol.10 , pp. 693-704
    • Minegishi, N.1    Suzuki, N.2    Kawatani, Y.3
  • 177
    • 34248343859 scopus 로고    scopus 로고
    • Cell cycle-dependent oscillation of GATA-2 expression in hematopoietic cells
    • Koga S, Yamaguchi N, Abe T et al. Cell cycle-dependent oscillation of GATA-2 expression in hematopoietic cells. Blood 2007;109:4200-4208.
    • (2007) Blood , vol.109 , pp. 4200-4208
    • Koga, S.1    Yamaguchi, N.2    Abe, T.3
  • 178
    • 0025977563 scopus 로고
    • Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
    • Pevny L, Simon MC, Robertson E et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 1991;349:257-260.
    • (1991) Nature , vol.349 , pp. 257-260
    • Pevny, L.1    Simon, M.C.2    Robertson, E.3
  • 179
    • 0032528484 scopus 로고    scopus 로고
    • Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo
    • Takahashi S, Komeno T, Suwabe N et al. Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo. Blood 1998;92:434-442.
    • (1998) Blood , vol.92 , pp. 434-442
    • Takahashi, S.1    Komeno, T.2    Suwabe, N.3
  • 180
    • 30444440180 scopus 로고    scopus 로고
    • Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells
    • Zheng J, Kitajima K, Sakai E et al. Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells. Blood 2006;107:520-527.
    • (2006) Blood , vol.107 , pp. 520-527
    • Zheng, J.1    Kitajima, K.2    Sakai, E.3
  • 181
    • 0028907850 scopus 로고
    • Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis
    • Labbaye C, Valtieri M, Barberi T et al. Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis. J Clin Invest 1995;95:2346-2358.
    • (1995) J Clin Invest , vol.95 , pp. 2346-2358
    • Labbaye, C.1    Valtieri, M.2    Barberi, T.3
  • 182
    • 0030926190 scopus 로고    scopus 로고
    • Trasncription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation
    • Tsai FY, Orkin SH. Trasncription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 1997;89:3636-3643.
    • (1997) Blood , vol.89 , pp. 3636-3643
    • Tsai, F.Y.1    Orkin, S.H.2
  • 183
    • 5444223724 scopus 로고    scopus 로고
    • GATA-2 plays two functional roles during ontogeny of hematopoietic stem cells
    • Ling KW, Ottersbach K, van Hamburg JP et al. GATA-2 plays two functional roles during ontogeny of hematopoietic stem cells. J Exp Med 2004;200:871-882.
    • (2004) J Exp Med , vol.200 , pp. 871-882
    • Ling, K.W.1    Ottersbach, K.2    van Hamburg, J.P.3
  • 184
    • 0041743226 scopus 로고    scopus 로고
    • Expression and domainspecific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation embryos
    • Minegishi N, Suzuki N, Yokomizo T et al. Expression and domainspecific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation embryos. Blood 2003;102:896-905.
    • (2003) Blood , vol.102 , pp. 896-905
    • Minegishi, N.1    Suzuki, N.2    Yokomizo, T.3
  • 185
    • 16844366556 scopus 로고    scopus 로고
    • RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
    • Robert-Moreno A, Espinosa L, de la Pompa JL et al. RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development 2005;132:1117-1126.
    • (2005) Development , vol.132 , pp. 1117-1126
    • Robert-Moreno, A.1    Espinosa, L.2    de la Pompa, J.L.3
  • 186
    • 33646008578 scopus 로고    scopus 로고
    • Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors
    • de Pooter RF, Schmitt TM, de la Pompa JL et al. Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors. J Immunol 2006;176:5267-5267.
    • (2006) J Immunol , vol.176 , pp. 5267-5267
    • de Pooter, R.F.1    Schmitt, T.M.2    de la Pompa, J.L.3
  • 188
    • 33644671508 scopus 로고    scopus 로고
    • Notch signalling in hematopoietic stem cells
    • Suzuki T, Chiba S. Notch signalling in hematopoietic stem cells. Int J Hematol 2005;82:285-294.
    • (2005) Int J Hematol , vol.82 , pp. 285-294
    • Suzuki, T.1    Chiba, S.2
  • 189
    • 4544359550 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Isolation and therapeutics
    • Alhadlaq A, Mao JJ. Mesenchymal stem cells: Isolation and therapeutics. Stem Cells Dev 2004;13:436-448.
    • (2004) Stem Cells Dev , vol.13 , pp. 436-448
    • Alhadlaq, A.1    Mao, J.J.2
  • 190
    • 33745503987 scopus 로고    scopus 로고
    • Mesenchymal stem cells reside in virtually all post-natal organs and tissues
    • da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 2006;119:2204-2213.
    • (2006) J Cell Sci , vol.119 , pp. 2204-2213
    • da Silva Meirelles, L.1    Chagastelles, P.C.2    Nardi, N.B.3
  • 192
    • 33847634900 scopus 로고    scopus 로고
    • Human first-trimester fetal MSC express pluripotency markers and grow faster and have longer telomeres than adult MSC
    • Guillot PV, Gotherstrom C, Chan J et al. Human first-trimester fetal MSC express pluripotency markers and grow faster and have longer telomeres than adult MSC. STEM CELLS 2007;25:646-654.
    • (2007) STEM CELLS , vol.25 , pp. 646-654
    • Guillot, P.V.1    Gotherstrom, C.2    Chan, J.3
  • 193
    • 34547120690 scopus 로고    scopus 로고
    • Concise review: Stem cell antigen-1: Expression, function, and enigma
    • Holmes C, Stanford WL. Concise review: Stem cell antigen-1: Expression, function, and enigma. STEM CELLS 2007;25:1339-1347.
    • (2007) STEM CELLS , vol.25 , pp. 1339-1347
    • Holmes, C.1    Stanford, W.L.2
  • 195
    • 33846572282 scopus 로고    scopus 로고
    • A rapid and efficient method for expansion of human mesenchymal stem cells
    • Both SK, Muijsenberg AJ, Blitterswijk CA et al. A rapid and efficient method for expansion of human mesenchymal stem cells. Tissue Eng 2007;13:3-9.
    • (2007) Tissue Eng , vol.13 , pp. 3-9
    • Both, S.K.1    Muijsenberg, A.J.2    Blitterswijk, C.A.3
  • 196
    • 2942523981 scopus 로고    scopus 로고
    • Mesenchymal stem cells can be differentiated into endothelial cells in vitro
    • Oswald J, Boxberger S, Jorgensen B et al. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. STEM CELLS 2004;22:377-384.
    • (2004) STEM CELLS , vol.22 , pp. 377-384
    • Oswald, J.1    Boxberger, S.2    Jorgensen, B.3
  • 197
    • 33846918135 scopus 로고    scopus 로고
    • SSEA-4 identifies mesenchymal stem cells from bone marrow
    • Gang EJ, Bosnakovski D, Figueiredo CA et al. SSEA-4 identifies mesenchymal stem cells from bone marrow. Blood 2007;109:1743-1751.
    • (2007) Blood , vol.109 , pp. 1743-1751
    • Gang, E.J.1    Bosnakovski, D.2    Figueiredo, C.A.3
  • 198
    • 33847607825 scopus 로고    scopus 로고
    • Differentiation potential of adult human mesenchymal stem cells
    • Pansky A, Roitzheim B, Tobiasch E. Differentiation potential of adult human mesenchymal stem cells. Clin Lab 2007;53:81-84.
    • (2007) Clin Lab , vol.53 , pp. 81-84
    • Pansky, A.1    Roitzheim, B.2    Tobiasch, E.3
  • 199
    • 33846699726 scopus 로고    scopus 로고
    • Single-cell-derived mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying cells
    • Yamada Y, Sakurada K, Takeda Y et al. Single-cell-derived mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying cells. Exp Cell Res 2007;313:698-706.
    • (2007) Exp Cell Res , vol.313 , pp. 698-706
    • Yamada, Y.1    Sakurada, K.2    Takeda, Y.3
  • 200
    • 33745499805 scopus 로고    scopus 로고
    • Mesenchymal stem cells spontaneously express neural proteins in culture and are neurogenic after transplantation
    • Deng J, Petersen BE, Steindler DA et al. Mesenchymal stem cells spontaneously express neural proteins in culture and are neurogenic after transplantation. STEM CELLS 2006;24:1054-1064.
    • (2006) STEM CELLS , vol.24 , pp. 1054-1064
    • Deng, J.1    Petersen, B.E.2    Steindler, D.A.3
  • 201
    • 33845983602 scopus 로고    scopus 로고
    • Functional neuronal differentiation of bone marrow-derived mesenchymal stem cells
    • Tropel P, Platet N, Platel JC et al. Functional neuronal differentiation of bone marrow-derived mesenchymal stem cells. STEM CELLS 2006;24:2868-2876.
    • (2006) STEM CELLS , vol.24 , pp. 2868-2876
    • Tropel, P.1    Platet, N.2    Platel, J.C.3
  • 202
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci U S A 1999;96:10711-10716.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 203
    • 33750121487 scopus 로고    scopus 로고
    • Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells
    • Talens-Visconti R, Bonora A, Jover R et al. Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells. World J Gastroenterol 2006;12:5834-5845.
    • (2006) World J Gastroenterol , vol.12 , pp. 5834-5845
    • Talens-Visconti, R.1    Bonora, A.2    Jover, R.3
  • 204
    • 33947265599 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cells differentiate into epidermal-like cells in vitro
    • Chun-mao H, Su-Yi W, Ping-Ping L et al. Human bone marrow-derived mesenchymal stem cells differentiate into epidermal-like cells in vitro. Differentiation 2007;75:292-298.
    • (2007) Differentiation , vol.75 , pp. 292-298
    • Chun-mao, H.1    Su-Yi, W.2    Ping-Ping, L.3
  • 205
    • 32344451060 scopus 로고    scopus 로고
    • Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells
    • Timper K, Seboek D, Eberhardt M et al. Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem Biophys Res Commun 2006;341:1135-1140.
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 1135-1140
    • Timper, K.1    Seboek, D.2    Eberhardt, M.3
  • 206
    • 33845865292 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells
    • Jeon SJ, Oshima K, Heller S et al. Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells. Mol Cell Neurosci 2007;34:59-68.
    • (2007) Mol Cell Neurosci , vol.34 , pp. 59-68
    • Jeon, S.J.1    Oshima, K.2    Heller, S.3
  • 207
    • 33847632532 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Molecular targets for tissue engineering
    • Satija NK, Gurudutta GU, Sharma S et al. Mesenchymal stem cells: Molecular targets for tissue engineering. Stem Cells Dev 2007;16:7-23.
    • (2007) Stem Cells Dev , vol.16 , pp. 7-23
    • Satija, N.K.1    Gurudutta, G.U.2    Sharma, S.3
  • 208
    • 33746061645 scopus 로고    scopus 로고
    • Inhibition of the proteasomal function in chondrocytes down-regulates growth plate chondrogenesis and longitudinal bone growth
    • Wu S, De Luca F. Inhibition of the proteasomal function in chondrocytes down-regulates growth plate chondrogenesis and longitudinal bone growth. Endocrinology 2006;147:3761-3768.
    • (2006) Endocrinology , vol.147 , pp. 3761-3768
    • Wu, S.1    De Luca, F.2
  • 209
    • 16844376927 scopus 로고    scopus 로고
    • Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin
    • Hwang SG, Yu SS, Ryu JH et al. Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin. J Biol Chem 2005;280:12758-12765.
    • (2005) J Biol Chem , vol.280 , pp. 12758-12765
    • Hwang, S.G.1    Yu, S.S.2    Ryu, J.H.3
  • 210
    • 0036920622 scopus 로고    scopus 로고
    • Regulation of the chondrocyte phenotype by beta-catenin
    • Ryu JH, Kim SJ, Kim SH et al. Regulation of the chondrocyte phenotype by beta-catenin. Development 2002;129:5541-5550.
    • (2002) Development , vol.129 , pp. 5541-5550
    • Ryu, J.H.1    Kim, S.J.2    Kim, S.H.3
  • 211
    • 33845221920 scopus 로고    scopus 로고
    • Control of peroxisome proliferator-activated receptor fate by the ubiquitin-proteasome system
    • Genini D, Catapano CV. Control of peroxisome proliferator-activated receptor fate by the ubiquitin-proteasome system. J Recept Signal Transduct Res 2006;26:679-692.
    • (2006) J Recept Signal Transduct Res , vol.26 , pp. 679-692
    • Genini, D.1    Catapano, C.V.2
  • 212
    • 0042134565 scopus 로고    scopus 로고
    • Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)
    • Cheng H, Jiang W, Phillips FM et al. Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am 2003;85-A:1544-1552.
    • (2003) J Bone Joint Surg Am , vol.85-A , pp. 1544-1552
    • Cheng, H.1    Jiang, W.2    Phillips, F.M.3
  • 213
    • 33646591275 scopus 로고    scopus 로고
    • Osteogenic differentiation of human mesenchymal stem cells is regulated by bone morphogenetic protein-6
    • Friedman MS, Long MW, Hankenson KD. Osteogenic differentiation of human mesenchymal stem cells is regulated by bone morphogenetic protein-6. J Cell Biochem 2006;98:538-554.
    • (2006) J Cell Biochem , vol.98 , pp. 538-554
    • Friedman, M.S.1    Long, M.W.2    Hankenson, K.D.3
  • 214
    • 0038819051 scopus 로고    scopus 로고
    • Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro
    • Garrett IR, Chen D, Gutierrez G et al. Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro. J Clin Invest 2003;111:1771-1782.
    • (2003) J Clin Invest , vol.111 , pp. 1771-1782
    • Garrett, I.R.1    Chen, D.2    Gutierrez, G.3
  • 215
    • 0035824568 scopus 로고    scopus 로고
    • Proteasomal degradation of Smad1 induced by bone morphogenetic proteins
    • Gruendler C, Lin Y, Farley J et al. Proteasomal degradation of Smad1 induced by bone morphogenetic proteins. J Biol Chem 2001;276:46533-46543.
    • (2001) J Biol Chem , vol.276 , pp. 46533-46543
    • Gruendler, C.1    Lin, Y.2    Farley, J.3
  • 217
    • 33645647676 scopus 로고    scopus 로고
    • Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation
    • Shen R, Chen M, Wang YJ et al. Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation. J Biol Chem 2006;281:3569-3576.
    • (2006) J Biol Chem , vol.281 , pp. 3569-3576
    • Shen, R.1    Chen, M.2    Wang, Y.J.3
  • 218
    • 33745212688 scopus 로고    scopus 로고
    • LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads
    • Sangadala S, Boden SD, Viggeswarapu M et al. LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads. J Biol Chem 2006;281:17212-17219.
    • (2006) J Biol Chem , vol.281 , pp. 17212-17219
    • Sangadala, S.1    Boden, S.D.2    Viggeswarapu, M.3


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