Teratocarcinomas and human embryology: Pluripotent human EC cell lines. Review article

APMIS

Volumn 106, Issue 1, 1998, Pages 158-168

  Andrews, Peter W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Differentiation; Embryonal carcinoma; Germ cell; Notch; Teratocarcinoma

Indexed keywords

BONE MORPHOGENETIC PROTEIN; GENE PRODUCT; HEXAMETHYLENEBISACETAMIDE; RETINOIC ACID;

CELL DIFFERENTIATION; CONFERENCE PAPER; CONTROLLED STUDY; EMBRYONAL CARCINOMA; GENE ACTIVATION; GENE EXPRESSION; GERM CELL TUMOR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TERATOCARCINOMA; TUMOR CELL LINE;

EID: 0031914244     PISSN: 09034641     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1699-0463.1998.tb01331.x     Document Type: Conference Paper

References (84)

1. Ackerman, S. L., Knowles, B. B. & Andrews, P. W.: Gene regulation during neuronal and non-neuronal differentiation of NTERA2 human teratocarcinoma-derived stem cells. MoI. Brain Res. 25: 157-162, 1994.
2. Andrews, P. W.: Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev. Biol. 103: 285-293, 1984.
3. Andrews, P. W.: Human teratocarcinoma. Biochim. Biophys. Acta. 948: 17-36, 1988.
4. Andrews, P. W. & Damjanov, I.: Cell lines from human germ cell tumors. In: Hay, R. J., Park, J.-G., Gazdar, A. (Eds.): Atlas of Human Tumor Cell Lines. Academic Press, 1994, pp. 443-476.
5. Andrews, P. W. & Goodfellow, P. N.: Antigen expression by somatic cell hybrids of a murine embryonal carcinoma cell with thymocytes and L cells. Somat. Cell Genet. 6: 271-284, 1980.
6. Andrews, P. W. & Wakeman, J.: Cell differentiation in germ cell tumours. In. Hughes, I. A. (Ed.) 'Sex Differentiation: clinical and biological aspects'. Frontiers in Endocrinology. 20: 33-44, 1996.
7. Andrews, P. W., Bronson, D. L., Benham, F., Strickland, S. & Knowles, B. B.: A comparative study of eight cell lines derived from human testicular teratocarcinoma. Int. J. Cancer. 26: 269-280, 1980.
8. Andrews, P. W., Goodfellow, P. N., Shevinsky, L., Bronson, D. L. & Knowles, B. B. : Cell surface antigens of a clonal human embryonal carcinoma cell line: Morphological and antigenic differentiation in culture. Int. J. Cancer. 29:523-531, 1982.
9. Andrews, P. W., Banting, G. S., Damjanov, I., Arnaud, D. & Avner, P.: Three monoclonal antibodies defining distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells. Hybridoma. 3: 347-361, 1984a.
10. Andrews, P. W., Damjanov, I., Simon, D., Banting, G., Carlin, C., Dracopoli, N. C. & Fogh, J.: Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2: Differentiation in vivo and in vitro. Lab. Invest. 50: 147-162, 1984b.
11. Andrews, P. W., Damjanov, I., Simon, D. & Dignazio, M.: A pluripotent human stem cell clone isolated from the TERA-2 teratocarcinoma line lacks antigens SSEA-3 and SSEA-4 in vitro but expresses these antigens when grown as a xenograft tumor. Differentiation. 29: 127-135, 1985.
12. Andrews, P. W., Nudelman, E., Hakomori, S.-I. & Fenderson, B. A.: Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR). Differentiation. 43: 131-138, 1990.
13. Andrews, P. W., Marrink, J., Hirka, G., von Keitz, A., Sleijfer, D. & Gönczöl, E.: The surface antigen phenotype of human embryonal carcinoma cells: Modulation upon differentiation and viral infection. In: Oosterhuis, J. W., Walt, H. & Damjanov, I. (Eds.): Recent Results in Cancer Research, Vol 123; Pathobiology of Human Germ Cell Neoplasia Springer-Verlag, 1991. pp. 63-83.
14. Andrews, P. W., Damjanov, I., Berends, J., Kumpf, S., Zappavingna, V., Mavilio, F. & Sampath, K.: Inhibition of proliferation and induction of differentiation of pluripotent human embryonal carcinoma cells by osteogenic protein-1 (or bone morphogenetic protein-7). Laboratory Investigation. 71: 243-251, 1994.
15. Andrews, P. W., Casper, J., Damjanov, I., Duggan-Keen, M., Giwercman, A., Hata, J. I., von Keitz, A., Looijenga, L. H. J., Millán, J. L., Oosterhuis, J. W., Pera, M., Sawada, M., Schmoll, H. J., Skakkebæk, N. E., van Putten, W. & Stern, P.: Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours. Int. J. Cancer. 66: 806-816, 1996.
16. Benham, F. J., Andrews, P. W., Bronson, D. L., Knowles, B. B. & Harris, H.: Alkaline phosphatase isozymes as possible markers of differentiation in human teratocarcinoma cell lines. Dev. Biol. 88: 279-287, 1981.
17. Berry, L. W., Westlund, B. & Schedl, T.: Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors. Development 124: 925-936, 1997.
18. Brinster, R. L.: The effect of cells transferred into the mouse blastocyst on subsequent development. J. Exp. Med. 140: 1049-1056, 1974.
19. Cooper, S., Pera, M. F., Bennett, W. & Finch, J. T.: A novel keratan sulphate proteoglycan from a human embryonal carcinoma cell line. Biochem. J. 286: 959-966, 1992.
20. Damjanov, I. & Solter, D.: Experimental teratoma. Curr. Topics Pathol. 59: 69-130, 1974.
21. Damjanov, I. & Andrews, P. W.: Ultrastructural differentiation of a clonal human embryonal carcinoma cell line in vitro. Cancer Res. 43: 2190-2198, 1983.
22. Damjanov, I. & Solter, D.: Experimental teratoma. Curr. Topics Pathol. 59: 69-130, 1974.
23. Damjanov, I., Horvat, B. & Gibas, Z.: Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT. Lab. Invest. 68: 220-232, 1993.
24. De Jong, F. H., de Winter, J. P., Wesseling, J. G., Timmerman, M. A., van Genesen, S., van den Eijnden van-Raaij, A. J. M. & van Zoelen, E. J. J.: Inhibin subunits, follistatin and activin receptors in the human teratocarcinoma cell line Tera-2. Biochem. Biophys. Res. Com. 192: 1334-1339, 1993.
25. Dixon, F. J. & Moore, R. A.: Testicular tumors: a clinico-pathologic study. Cancer 6: 427-454, 1953.
26. Dono, R., Montuori, N., Rocchi, M., de Pontizilli, L., Ciccodicola, A. & Persico, M. G.: Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence. Am. J. Hum. Genet. 49: 555-565, 1991.
27. Ducibella, T., Anderson, D., Aalberg, J., DeWolf, W. C.: Cell surface polarisation, tight junctions and eccentric inner cells characterize human teratocarcinoma embryoid bodies. Devel. Biol. 94: 197-205, 1982.
28. Ellisen, L. W., Bird, J., West, D. C., Soreng, A. L., Reynolds, T. C., Smith, S. D. & Sklar, J.: TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell, 66: 649-661, 1991.
29. Evans, M. J. & Kaufman, M. H,: Establishment in culture of pluripotential from mouse embryos. Nature 292: 154-156, 1981.
30. Fenderson, B. A., Andrews, P. W., Nudelman, E., Clausen, H. & Hakomori, S.-I.: Glycolipid core structure switching from globo-to lacto- and ganglio-series during retinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells. Dev. Biol. 122: 21-34, 1987.
31. Fogh, J. & Trempe, G.: New human tumor cell lines. In: Fogh, J. (Ed): Human tumor cells in vitro. Plenum Press, NY., 1975, pp 115-159.
32. Friedman, N. B. & Moore, R. A.: Tumors of the testis. A report of 922 cases. Milit. Surg. 99: 573-593, 1946.
33. Giwercman, A., Andrews, P. W., Jorgensen, N., Muller, J., Graem, N. & Skakkebæk, N. E.: Immunochemical expression of embryonal marker TRA-1-60 in carcinoma in situ germ cells and in testicular germ cell tumours. Cancer 72: 1308-1314, 1993.
34. Gönczöl, E., Andrews, P. W. & Plotkin, S. A.: Cytomegalovirus replicates in differentiated but not undifferentiated human embryonal carcinoma cells. Science 224: 159-161, 1984.
35. Hardy, M., Younkin, D., Tang, C. M., Pleasure, J., Shi, Q. Y., Williams, M. & Pleasure, D: Expression of non-NMDA glutamate receptor channel genes by clonal human neurons. J. Neurochem. 63: 482-489, 1994.
36. Hata, J., Fujimoto, J., Ishii, E., Umezawa, A., Kokai, Y., Matsubayashi, Y., Abe, H., Kusakari, S., Kikuchi, H., Yamada, T. & Maruyama, T.: Differentiation of human germ cell tumor cells in vivo and in vitro. Acta Histochem. Cytochem. 25: 563-576, 1992.
37. Hemmuti-Brivanlou, A. & Melton, D.: Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell, 88: 13-17, 1997.
38. Hirka, G., Prakesh, K., Kawashima, H., Plotkin, S. A., Andrews, P. W. & Gönczöl, E.: Differentiation of human embryonal carcinoma cells induces human immunodeficiency virus permissiveness which is stimulated by human cytomegalovirus coinfection. J. Virol. 65: 2732-2735, 1991.
39. Huang, T. H., Oka, T., Asai, T., Okada, T., Merrills, B. W., Gertson, P. N., Whitson, R. H. & Itakura, K.: Repression by a differentiation-specific factor of the human cytomegalovirus enhancer. Nuc. Acids Res. 24: 1695-1701, 1996.
40. Izhar, M., Siebert, P. D., Oshima, R. G., DeWolf, W. C. & Fukuda, M. N.: Trophoblastic differentiation of human teratocarcinoma cell line HT-H. Developmental Biology 116: 510-518, 1986.
41. Jakob, H., Boon, T., Gaillard, J., Nicholas, J. F. & Jacob, F.: Teratocarcinome de la souris: isolement, culture, et proprietés de cellules à potentialités multiples. Ann. Microbiol. (Inst. Pasteur) 124B: 269-282, 1973.
42. Kannagi, R., Cochran, N. A., Ishigami, F., Hakomori, S.-I., Andrews, P. W., Knowles, B. B. & Solter, D.: Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. The EMBO J. 2: 2355-2361, 1983.
43. Kapoor, R. & Prehm, P.: Changes in proteoglycan composition of F9 teratocarcinoma cells upon differentiation. Eur. J. Biochem. 137: 589-595, 1983.
44. Kleinsmith, L. J. & Pierce, G. B.: Multipotentiality of single embryonal carcinoma cells. Cancer Res. 24: 1544-1552, 1962.
45. Kleppner, S. R., Robinson, K. A., Trojanowski, J. Q. & Lee, V. M. Y.: Transplanted human neurons derived from a teratocarcinoma cell line (NTERA2) mature, integrate, and survive for over I year in the nude mouse brain. J. Comp. Neurol. 357: 618-632, 1995.
46. Krupnick, J. G., Damjanov, I., Dumjanov, A., Zhu, Z. M. & Fenderson, B. A.: Globo-series carbohydrate antigens are expressed in different forms on human and murine teratocarcinoma-derived cells. Int. J. Cancer, 59; 692-698, 1994.
47. Lee, V. M. Y. & Andrews, P. W.: Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins. J. Neurosci. 6: 514-521, 1986.
48. Marrink, J., Andrews, P. W., van Brummen, P. J., de Jong, H. J., Sleijfer, D., Schrajfordt-Koops, H. & Oosterhuis, J. W.: TRA-1-60: A new serum marker in patients with germ cell tumors. Int. J. Cancer 49: 368-372, 1991.
49. Martin, G. R.: Teratocarcinomas and mammalian embryogenesis. Science 209: 768-775, 1980.
50. Martin, G. R. & Evans, M. J.: Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. Proc. Natl. Acad. Sci. USA 72: 1441-1445, 1975.
51. Maruyama,T., Umezawa, A., Kusakari, S., Kikuchi, H., Nozaki, M., Hata, J. I.: Heat shock induces differentiation of human embryonal carcinoma cells into trophectoderm lineages. Exp. Cell Res. 224: 123-127, 1996.
52. Matsui, Y., Zsebo, K. & Hogan, B. L. M.: Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell 70: 841-847, 1992.
53. Matthaei, K., Andrews, P. W. & Bronson, D. L.: Retinoic acid fails to induce differentiation in human teratocarcinoma cell lines that express high levels of cellular receptor protein. Exp. Cell Res. 143: 471-474, 1983.
54. Miller, W. H., Maerz, W. J., Kurie, J., Moy, D., Baselga, J., Lucas, D. A., Grippo, J.F., Masui, H. & Dmitrovsky, E.: All trans-retinoic acid and hexamethylene bisacetamide(HMBA) regulateTGF-alpha and Hst-1/kFGF expression in differentiation sensitive but not in resistant human teratocarcinomas. Differentiation 55: 145-152, 1994.
55. Miyazono, M., Lee, K M. Y. & Trojanowski, J. Q.: Proliferation, cell death, and neuronal differentiation in transplanted human embryonal carcinoma (NTERA2) cells depend on the graft site in nude and severe combined immunodeficient mice. Lab. Invest. 73: 273-283, 1995.
56. Miyazono, M., Nowell, P. C., Finan, J. L., Lee, V. M. Y. & Trojanowski, J. Q.: Long-term integration and neuronal differentiation of human embryonal carcinoma cells (NTERA2) transplanted into the caudoputamen of nude mice. J. Comp. Neurol. 376: 603-613, 1996.
57. Moasser, M. M., DeBlasio, A. & Dmitrovsky, E.: Response and resistance to retinoic acid are mediated through the retinoic acid nuclear receptorgamma in human teratocarcinomas. 9: 833-840, 1994.
58. Moasser, M. M., Reuter, K E. & Dmitrovsky, E.: Overexpression of the retinoic acid receptorgamma directly induces terminal differentiation of human embryonal carcinoma cells. 10: 1537-1543, 1995.
59. Papaioannou, V. E., McBurney, M. W., Gardner, R. L. & Evans, M. J.: Fate of teratocarcinoma cells injected into early mouse embryos. Nature 258: 70-73, 1975.
60. Pera, M. F., Blasco-Lafite, M. J., Cooper, S., Mason, M., Mills, J. & Monoghan, P.: Analysis of cell differentiation lineage in human teratomas using new monoclonal antibodies to cytostructural antigens of embryonal carcinoma cells. Differentiation 39: 139-149, 1988.
61. Peru, M. F., Cooper, S., Mills, J. & Parrington, J. M.: Isolation and characterization of a multipotent clone of human embryonal carcinoma cells. Differentiation 42: 10-23, 1989.
62. Pierce, G. B., Verney, E. L. & Dixon, F. J.: The biology of testicular cancer. I. Behaviour after transplantation. Cancer Res. 17: 134-138, 1957.
63. Pierce, G. B., Dixon, F. J. & Verney, E. L.: Teratocarcinogenic and tissue forming potentialities of the cell types comprising neoplastic embryoid bodies. Lab. Invest. 9: 583-602, 1960.
64. Pleasure, S. J. & Lee, V. M. Y.: NTera 2 cells: A human cell line which displays characteristics expected of a human committed neuronal progenitor cell. J. Neurosci. Res. 35: 585-602, 1993.
65. Pleasure, S. J., Page, C. & Lee, V. M. Y.: Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J. Neurosc. 12: 1802-1815, 1992.
66. Race, R. R. & Sanger, R.: Blood Groups in Man. Sixth Edition. Blackwell Scientific Publications. Oxford 1975. pp. 169-171.
67. Rettig, W. J., Cordon-Cardo, C., Ng, J. S. C., Oettgen, H. F., Old, L. J. & Lloyd, K. O.: High molecular weight glycoproteins of human teratocarcinoma defined by monoclonal antibodies to carbohydrate determinants. Cancer Res. 45: 815-821, 1985.
68. Rendt, J., Erulkar, S. & Andrews, P. W.: Presumptive neurons derived by differentiation of a human embryonal carcinoma cell line exhibit tetrodotoxin-sensitive sodium currents and the capacity for regenerative responses. Exp. Cell Res. 180: 580-584, 1989.
69. Roach, S., Schmid, W. & Pera, M. F.: Hepatocytic transcription factor expression in human; embryonal carcinoma and yolk sac carcinoma cell lines: Expression of HNF3alpha in models of early endodermal cell differentiation. Exp. Cell Res. 215: 189-198, 1994.
70. Shelbourn, S. L. Kothari, S. K., Sissons, J. G. P. & Sinclair, J. H.: Repression of human cytomegalovirus gene expression associated with a novel intermediate early regulatory region binding factor. Nuc. Acids Res. 17: 9165-9171, 1989.
71. Simeone, A., Acampora, D., Arcioni, L., Andrews, P. W., Boncinelli, E. & Mavilio, F.: Sequential activation of human HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells. Nature 346: 763-766, 1990.
72. Skakkebæk, N. E., Berthelsen, J. G., Giwercman, A. & Mailer, J: Carcinoma in situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. Int. J. Androl. 10: 19-28, 1987.
73. Solter, D. & Damjanov, I.: Teratocarcinoma and the expression of oncodevelopmental genes. Methods in Cancer Research 18: 277-332, 1979.
74. Solter, S., Škreb, N. & Damjanov, L: Extrauterine growth of mouse egg-cylinders results in malignant teratoma. Nature 277: 503-504, 1970.
75. Squires, P. E., Wakeman, J. A., Chapman, H., Kumpf, S., Fiddock, M. D., Andrews, P. W. & Dunne, M. J.: Regulation of intracellular Ca2+ in response to muscarinic and glutamate receptor agonists during the differentiation of NTERA2 human embryonal carcinoma cells into neurons. European J. Neurosci. 8: 783-793, 1996.
76. Stevens, L. C.: The biology of teratomas. Adv. Morphol. 6: 1-31, 1967a.
77. Stevens, L. C.: Origin of testicular teratomas from primordial germ cells in mice. J. Natl. Cancer Inst. 38: 549-552, 1967b.
78. Strickland, S. & Mahdavi, K: The induction of differentiation of teratocarcinoma stem cells by retinoic acid. Cell 15: 393-403, 1978.
79. Teshima, S., Shimosato, Y., Hirohashi, S., Tome, Y., Hayashi, I., Kanazawa, H. & Kakizoe, T.: Four new human germ cell tumor cell lines. Lab. Invest. 59: 328-336, 1988.
80. Thompson, S., Stern, P. L., Webb., M., Walsh, F. S., Engström, W., Evans, E. P., Shi, W. K., Hopkins, B. & Graham, C. F.: Coned human teratoma cells differentiate into neuron-like cells and other cell types in retinoic acid. J. Cell Sci. 72: 37-64, 1984.
81. Thomson, J. A., Kalishman, J., Golos, T. G., Durning, M., Harris, C. P., Becker, R. A. & Hearn, J. P.: Isolation of a primate embryonic stem cell line. Proc. Natl. Acad. Sci. USA 92: 7844-7848, 1995.
82. Tippen, P., Andrews, P. W., Knowles, B. B., Solter, D. & Goodfellow, P. N.: Red cell antigens P (globoside) and Luke: Identification by monoclonal antibodies defining the murine stage-specific embryonic antigens -3 and -4 (SSEA-3 and -4). Vox Sang. 51: 53-56, 1986.
83. Wenk, J., Andrews, P. W., Casper, J., Hata, J-I., Pera, M. F., von Keitz, A., Damjanov, I. & Fenderson, B. A.: Glycolipids of germ cell tumours: extended globo-series glycolipids are a hallmark of human embryonal carcinoma cells. Int. J. Cancer. 58: 108-115, 1994.
84. Wheeler, J.: History of teratomas. In: Damjanov, J., Knowles, B. B. & Solter, D. (Eds): The Human Teratomas: Experimental and Clinical Biology. Humana Press, Clifton, NJ., 1983, pp. 1-22.