-
3
-
-
11244315697
-
-
Manalo, D.J., Rowan, A., Lavoie, T., Natarajan, L., Kelly, B.D., Ye, S.Q., Garcia, J.G. & Semenza, G.L (2005) Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-I. 105, 659-669
-
(2005)
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-I
, vol.105
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.7
Semenza, G.L.8
-
5
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza, G.L (2003) Targeting HIF-1 for cancer therapy. Not. Rev. Cancer 3, 721-732
-
(2003)
Not. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
6
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara, N. & Kerbel, R.S. (2005) Angiogenesis as a therapeutic target. Nature 438, 967-974
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
7
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouysségur, J., Dayan, F. & Mazure, N.M. (2006) Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441, 437-443
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouysségur, J.1
Dayan, F.2
Mazure, N.M.3
-
8
-
-
10444223878
-
The hypoxia-inducible factor and tumor progression along the angiogenic pathway
-
Brahimi-Hom, M.C. & Pouyssegur, J. (2005) The hypoxia-inducible factor and tumor progression along the angiogenic pathway. Int Rev. Cytol. 242, 157-213
-
(2005)
Int Rev. Cytol
, vol.242
, pp. 157-213
-
-
Brahimi-Hom, M.C.1
Pouyssegur, J.2
-
9
-
-
0037837724
-
Multiple splice variants of the human HIF-3α locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex
-
Maynard, M.A., Qi, H., Chung, J., Lee, E.H., Kondo, Y., Hara, S., Conaway, R.C., Conaway, J.W. & Ohh, M. (2003) Multiple splice variants of the human HIF-3α locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. J. Biol. Chem. 278, 11032-11040
-
(2003)
J. Biol. Chem
, vol.278
, pp. 11032-11040
-
-
Maynard, M.A.1
Qi, H.2
Chung, J.3
Lee, E.H.4
Kondo, Y.5
Hara, S.6
Conaway, R.C.7
Conaway, J.W.8
Ohh, M.9
-
10
-
-
0035969508
-
Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression
-
Makino, Y., Cao, R., Svensson, K., Bertilsson, G., Asman, M., Tanaka, H., Cao, Y., Berkenstam, A. & Poellinger, L (2001) Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature 414, 550-554
-
(2001)
Nature
, vol.414
, pp. 550-554
-
-
Makino, Y.1
Cao, R.2
Svensson, K.3
Bertilsson, G.4
Asman, M.5
Tanaka, H.6
Cao, Y.7
Berkenstam, A.8
Poellinger, L.9
-
11
-
-
0031971047
-
Expression of ARNT, ARNT2, HIF 1α, HIF2α and Ah receptor mRNAs in the developing mouse
-
Jain, S., Maltepe, E., Lu, M.M., Simon, C. & Bradfield, C.A. (1998) Expression of ARNT, ARNT2, HIF 1α, HIF2α and Ah receptor mRNAs in the developing mouse. Mech. Dev. 73, 117-123
-
(1998)
Mech. Dev
, vol.73
, pp. 117-123
-
-
Jain, S.1
Maltepe, E.2
Lu, M.M.3
Simon, C.4
Bradfield, C.A.5
-
12
-
-
33751344759
-
ARDent about acetylation and deacetylation in hypoxia signalling
-
Bilton, R., Trottier, E., Pouysségur, J. & Brahimi-Horn, M.C. (2006) ARDent about acetylation and deacetylation in hypoxia signalling. Trends Cell Biol. 16, 616-621
-
(2006)
Trends Cell Biol
, vol.16
, pp. 616-621
-
-
Bilton, R.1
Trottier, E.2
Pouysségur, J.3
Brahimi-Horn, M.C.4
-
13
-
-
4644370374
-
Signalling via the hypoxia-inducible factor-1α requires multiple posttranslational modifications
-
Brahimi-Horn, C., Mazure, N. & Pouysségur, J. (2005) Signalling via the hypoxia-inducible factor-1α requires multiple posttranslational modifications. Cell. Signalling 17, 1-9
-
(2005)
Cell. Signalling
, vol.17
, pp. 1-9
-
-
Brahimi-Horn, C.1
Mazure, N.2
Pouysségur, J.3
-
15
-
-
0142182783
-
The von Hippel-Lindau gene, kidney cancer, and oxygen sensing
-
Kaelin, Jr, W.G. (2003) The von Hippel-Lindau gene, kidney cancer, and oxygen sensing. J. Am. Soc. Nephrol. 14, 2703-2711
-
(2003)
J. Am. Soc. Nephrol
, vol.14
, pp. 2703-2711
-
-
Kaelin Jr, W.G.1
-
16
-
-
33745779304
-
Regulation of HIF: Asparaginyl hydroxylation
-
discussion 49-53, 131-140
-
Peet, D. & Linke, S. (2006) Regulation of HIF: asparaginyl hydroxylation. Novartis Found. Symp. 272, 37-49; discussion 49-53, 131-140
-
(2006)
Novartis Found. Symp
, vol.272
, pp. 37-49
-
-
Peet, D.1
Linke, S.2
-
17
-
-
33645735151
-
The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1α
-
Dayan, F., Roux, D., Brahimi-Horn, M.C., Pouysségur, J. & Mazure, N.M. (2006) The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1α. Cancer Res. 66, 3688-3698
-
(2006)
Cancer Res
, vol.66
, pp. 3688-3698
-
-
Dayan, F.1
Roux, D.2
Brahimi-Horn, M.C.3
Pouysségur, J.4
Mazure, N.M.5
-
18
-
-
33646764243
-
Hypoxia-inducible factors, hypoxia, and tumor angiogenesis
-
Gruber, M. & Simon, M.C. (2006) Hypoxia-inducible factors, hypoxia, and tumor angiogenesis. Curr. Opin. Hematol. 13, 169-174
-
(2006)
Curr. Opin. Hematol
, vol.13
, pp. 169-174
-
-
Gruber, M.1
Simon, M.C.2
-
19
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby, R.A. & Gillies, R.J. (2004) Why do cancers have high aerobic glycolysis? Nat Rev. Cancer 4, 891-899
-
(2004)
Nat Rev. Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
20
-
-
29644442625
-
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
-
Lu, H., Dalgard, C.L., Mohyeldin, A., McFate, T., Tait, A.S. & Verma, A. (2005) Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J. Biol. Chem. 280, 41928-41939
-
(2005)
J. Biol. Chem
, vol.280
, pp. 41928-41939
-
-
Lu, H.1
Dalgard, C.L.2
Mohyeldin, A.3
McFate, T.4
Tait, A.S.5
Verma, A.6
-
21
-
-
24144467846
-
ROS: Really involved in oxygen sensing
-
Kaelin, Jr, W.G. (2005) ROS: really involved in oxygen sensing. Cell Metab. 1, 357-358
-
(2005)
Cell Metab
, vol.1
, pp. 357-358
-
-
Kaelin Jr, W.G.1
-
22
-
-
33750622643
-
Redox regulation of the hypoxia-inducible factor
-
Pouysségur, J. & Mechta-Grigoriou, F. (2006) Redox regulation of the hypoxia-inducible factor. Biol. Chem. 387, 1337-1346
-
(2006)
Biol. Chem
, vol.387
, pp. 1337-1346
-
-
Pouysségur, J.1
Mechta-Grigoriou, F.2
-
23
-
-
27844526600
-
Akt-dependent transformation: There is more to growth than just surviving
-
Plas, D.R. & Thompson, C.B. (2005) Akt-dependent transformation: there is more to growth than just surviving. Oncogene 24, 7435-7442
-
(2005)
Oncogene
, vol.24
, pp. 7435-7442
-
-
Plas, D.R.1
Thompson, C.B.2
-
24
-
-
33748752151
-
The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
-
Schieke, S.M., Phillips, D., McCoy, Jr, J.P., Aponte, A.M., Shen, R.F., Balaban, R.S. & Finkel, T. (2006) The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J. Biol. Chem 281, 27643-27652
-
(2006)
J. Biol. Chem
, vol.281
, pp. 27643-27652
-
-
Schieke, S.M.1
Phillips, D.2
McCoy Jr, J.P.3
Aponte, A.M.4
Shen, R.F.5
Balaban, R.S.6
Finkel, T.7
-
25
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim, J.W., Tchernyshyov, I., Semenza, G.L. & Dang, C.V. (2006) HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2, 177-185
-
(2006)
Cell Metab
, vol.2
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
26
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou, I., Cairns, R.A., Fontana, L., Lim, A.L & Denko, N.C. (2006) HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 3, 187-197
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
27
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
Fantin, V.R., St-Pierre, J. & Leder, P. (2006) Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9, 425-434
-
(2006)
Cancer Cell
, vol.9
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
28
-
-
11144353536
-
18F]fluorodeoxyglucose positron emission tomography imaging
-
18F]fluorodeoxyglucose positron emission tomography imaging. Clin. Cancer Res. 10, 2245-2252
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 2245-2252
-
-
Rajendran, J.G.1
Mankoff, D.A.2
O'Sullivan, F.3
Peterson, L.M.4
Schwartz, D.L.5
Conrad, E.U.6
Spence, A.M.7
Muzi, M.8
Farwell, D.G.9
Krohn, K.A.10
-
29
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
King, A., Selak, M.A. & Gottlieb, E. (2006) Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer. Oncogene 25, 4675-4682
-
(2006)
Oncogene
, vol.25
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
30
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations
-
Pollard, P.J., Briere, J.J., Alam, N.A., Barwell, J., Barclay, E., Wortham, N.C., Hunt, T., Mitchell, M., Olpin, S., Moat, S.J. et al. (2005) Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations. Hum. Mol. Genet. 14, 2231-2239
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 2231-2239
-
-
Pollard, P.J.1
Briere, J.J.2
Alam, N.A.3
Barwell, J.4
Barclay, E.5
Wortham, N.C.6
Hunt, T.7
Mitchell, M.8
Olpin, S.9
Moat, S.J.10
-
31
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad, K., Tsuruta, A., Selak, M.A., Vidal, M.N., Nakano, K., Bartrons, R., Gottlieb, E. & Vousden, K.H. (2006) TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126, 107-120
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
32
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh, H., Lleonart, M.E., Gil, J., Wang, J., Degan, P., Peters, G., Martinez, D., Carnero, A. & Beach, D. (2005) Glycolytic enzymes can modulate cellular life span. Cancer Res. 65, 177-185
-
(2005)
Cancer Res
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
33
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba, S., Kang, J.G., Patino, W.D., Wragg, A., Boehm, M., Gavrilova, O., Hurley, P.J., Bunz, F. & Hwang, P.M. (2006) p53 regulates mitochondrial respiration. Science 312, 1650-1653
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
34
-
-
13444283313
-
Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1α, causing gl/colysis shutdown and cell death
-
Blum, R., Jacob-Hirsch, J., Amariglio, N., Rechavi, G. & Kloog, Y. (2005) Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1α, causing gl/colysis shutdown and cell death. Cancer Res. 65, 999-1006
-
(2005)
Cancer Res
, vol.65
, pp. 999-1006
-
-
Blum, R.1
Jacob-Hirsch, J.2
Amariglio, N.3
Rechavi, G.4
Kloog, Y.5
-
35
-
-
2942701935
-
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays
-
Kim, J.W., Zeller, K.I., Wang, Y., Jegga, A.G., Aronow, B.J., O'Donnell, K.A. & Dang, C.V. (2004) Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol. Cell Biol. 24, 5923-5936
-
(2004)
Mol. Cell Biol
, vol.24
, pp. 5923-5936
-
-
Kim, J.W.1
Zeller, K.I.2
Wang, Y.3
Jegga, A.G.4
Aronow, B.J.5
O'Donnell, K.A.6
Dang, C.V.7
-
36
-
-
32044435126
-
Coordination and communication between the p53 and IGF-1-Akt-TOR signal transduction pathways
-
Levine, A.J., Feng, Z., Mak, T.W., You, H. & Jin, S. (2006) Coordination and communication between the p53 and IGF-1-Akt-TOR signal transduction pathways. Genes Dev. 20, 267-275
-
(2006)
Genes Dev
, vol.20
, pp. 267-275
-
-
Levine, A.J.1
Feng, Z.2
Mak, T.W.3
You, H.4
Jin, S.5
-
37
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
Shaw, R.J. & Cantley, L.C. (2006) Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441, 424-430
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
39
-
-
33745110220
-
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
-
Gerweck, L.E., Vijayappa, S. & Kozin, S. (2006) Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics. Mol. Cancer Ther. 5, 1275-1279
-
(2006)
Mol. Cancer Ther
, vol.5
, pp. 1275-1279
-
-
Gerweck, L.E.1
Vijayappa, S.2
Kozin, S.3
-
40
-
-
33646917296
-
The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-17alpha; dependent mechanism
-
Ullah, M.S., Davies, A.J. & Halestrap, A.P. (2006) The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-17alpha; dependent mechanism. J. Biol. Chem. 281, 9030-9037
-
(2006)
J. Biol. Chem
, vol.281
, pp. 9030-9037
-
-
Ullah, M.S.1
Davies, A.J.2
Halestrap, A.P.3
-
41
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
Svastova, E., Hulikova, A., Rafajova, M., Zat'ovicova, M., Gibadulinova, A., Casini, A., Cecchi, A., Scozzafava, A., Supuran, C.T., Pastorek, J. & Pastorekova, S. (2004) Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett. 577, 439-445
-
(2004)
FEBS Lett
, vol.577
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
Zat'ovicova, M.4
Gibadulinova, A.5
Casini, A.6
Cecchi, A.7
Scozzafava, A.8
Supuran, C.T.9
Pastorek, J.10
Pastorekova, S.11
-
44
-
-
33751117499
-
HIF-1 regulates hypoxic induction of NHEI expression and alkalinization of intracellular pH in pulmonary arterial myocytes
-
Shimoda, L.A., Fallon, M., Pisarcik, S., Wang, J. & Semenza, G.L (2006) HIF-1 regulates hypoxic induction of NHEI expression and alkalinization of intracellular pH in pulmonary arterial myocytes. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L941-L949
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.291
-
-
Shimoda, L.A.1
Fallon, M.2
Pisarcik, S.3
Wang, J.4
Semenza, G.L.5
-
45
-
-
28844503376
-
Transport activity of MCT1 expressed in Xenopus oocytes is increased by interaction with carbonic anhydrase
-
Becker, H.M., Hirnet, D., Fecher-Trost, C., Sultemeyer, D. & Deitmer, J.W. (2005) Transport activity of MCT1 expressed in Xenopus oocytes is increased by interaction with carbonic anhydrase. J. Biol. Chem 280, 39882-39889
-
(2005)
J. Biol. Chem
, vol.280
, pp. 39882-39889
-
-
Becker, H.M.1
Hirnet, D.2
Fecher-Trost, C.3
Sultemeyer, D.4
Deitmer, J.W.5
-
46
-
-
13944252559
-
Identification of membrane type-1 matrix metal-loproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma
-
Petrella, B.L., Lohi, J. & Brinckerhoff, C.E. (2005) Identification of membrane type-1 matrix metal-loproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma. Oncogene 24, 1043-1052
-
(2005)
Oncogene
, vol.24
, pp. 1043-1052
-
-
Petrella, B.L.1
Lohi, J.2
Brinckerhoff, C.E.3
-
47
-
-
33744942376
-
Acid-mediated tumor invasion: A multidisciplinary study
-
Gatenby, R.A., Gawlinski, E.T., Gmitro, A.F., Kaylor, B. & Gillies, R.J. (2006) Acid-mediated tumor invasion: a multidisciplinary study. Cancer Res. 66, 5216-5223
-
(2006)
Cancer Res
, vol.66
, pp. 5216-5223
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
Gmitro, A.F.3
Kaylor, B.4
Gillies, R.J.5
-
48
-
-
3142588858
-
Lactate: Mirror and motor of tumor malignancy
-
Walenta, S. & Mueller-Klieser, W.F. (2004) Lactate: mirror and motor of tumor malignancy. Semin. Radiat Oncol. 14, 267-274
-
(2004)
Semin. Radiat Oncol
, vol.14
, pp. 267-274
-
-
Walenta, S.1
Mueller-Klieser, W.F.2
-
49
-
-
9344260855
-
Autocrine motility factor signaling enhances pancreatic cancer metastasis
-
Tsutsumi, S., Yanagawa, T., Shimura, T., Kuwano, H. & Raz, A. (2004) Autocrine motility factor signaling enhances pancreatic cancer metastasis. Clin. Cancer Res. 10, 7775-7784
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 7775-7784
-
-
Tsutsumi, S.1
Yanagawa, T.2
Shimura, T.3
Kuwano, H.4
Raz, A.5
-
50
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
Pennacchietti, S., Michieli, P., Galluzzo, M., Mazzone, M., Giordano, S. & Comoglio, P.M. (2003) Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 3, 347-361
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
Michieli, P.2
Galluzzo, M.3
Mazzone, M.4
Giordano, S.5
Comoglio, P.M.6
-
51
-
-
0141828145
-
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
-
Staller, P., Sulitkova, J., Lisztwan, J., Moch, H., Oakeley, E.J. & Krek, W. (2003) Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL Nature 425, 307-311
-
(2003)
Nature
, vol.425
, pp. 307-311
-
-
Staller, P.1
Sulitkova, J.2
Lisztwan, J.3
Moch, H.4
Oakeley, E.J.5
Krek, W.6
-
52
-
-
33845724527
-
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and Snail
-
Evans, A.J., Russell, R.C., Roche, O., Burry, T.N., Fish, J.E., Chow, V.W., Kim, W.Y., Saravanan, A., Maynard, M.A., Gervais, M.L. et al. (2006) VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and Snail. Mol. Cell Biol. 27, 157-169
-
(2006)
Mol. Cell Biol
, vol.27
, pp. 157-169
-
-
Evans, A.J.1
Russell, R.C.2
Roche, O.3
Burry, T.N.4
Fish, J.E.5
Chow, V.W.6
Kim, W.Y.7
Saravanan, A.8
Maynard, M.A.9
Gervais, M.L.10
-
53
-
-
17144416875
-
Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment
-
Papandreou, I., Krishna, C., Kaper, F., Cai, D., Giaccia, A.J. & Denko, N.C. (2005) Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment. Cancer Res. 65, 3171-3178
-
(2005)
Cancer Res
, vol.65
, pp. 3171-3178
-
-
Papandreou, I.1
Krishna, C.2
Kaper, F.3
Cai, D.4
Giaccia, A.J.5
Denko, N.C.6
-
54
-
-
33749362031
-
Inhibiting hypoxia-inducible factor I for cancer therapy
-
Melillo, G. (2006) Inhibiting hypoxia-inducible factor I for cancer therapy. Mol. Cancer Res. 4, 601-605
-
(2006)
Mol. Cancer Res
, vol.4
, pp. 601-605
-
-
Melillo, G.1
|