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Volumn 20, Issue 3, 2007, Pages 539-555

The prominent role of p38 mitogen-activated protein kinase in insulin-mediated enhancement of VCAM-1 expression in endothelial cells

Author keywords

Atherosclerosis; Diabetes; Insulin; Insulin resistance; MAP kinases

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; LY 379196; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; SMALL INTERFERING RNA; SP 600127; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; WORTMANNIN;

EID: 34948861614     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200702000312     Document Type: Article
Times cited : (31)

References (60)
  • 1
    • 0037092995 scopus 로고    scopus 로고
    • Diabetes and atherosclerosis: Epidemiology, pathophysiology, and management
    • Beckman J.A., M.A. Creager and P. Libby. 2002. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 287: 2570.
    • (2002) JAMA , vol.287 , pp. 2570
    • Beckman, J.A.1    Creager, M.A.2    Libby, P.3
  • 2
    • 0029840022 scopus 로고    scopus 로고
    • The UK Prospective Diabetes Study. UK Prospective Diabetes Study Group
    • Turner R.C. and R.R. Holman. 1996. The UK Prospective Diabetes Study. UK Prospective Diabetes Study Group. Ann. Med. 28:439.
    • (1996) Ann. Med , vol.28 , pp. 439
    • Turner, R.C.1    Holman, R.R.2
  • 3
    • 0029886687 scopus 로고    scopus 로고
    • Hyperinsulinemia and atherosclerosis
    • Stout R.W. 1996. Hyperinsulinemia and atherosclerosis. Diabetes 45(S):45.
    • (1996) Diabetes , vol.45 , Issue.S , pp. 45
    • Stout, R.W.1
  • 5
    • 4043058031 scopus 로고    scopus 로고
    • Advanced glycation end products and vascular inflammation: Implications for accelerated atherosclerosis in diabetes
    • Basta G., A.M. Schmidt and R. De Caterina. 2004. Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes. Cardiovasc. Res. 63:582.
    • (2004) Cardiovasc. Res , vol.63 , pp. 582
    • Basta, G.1    Schmidt, A.M.2    De Caterina, R.3
  • 6
    • 0029760006 scopus 로고    scopus 로고
    • Insulin resistance and coronary heart disease
    • Laakso M. 1996. Insulin resistance and coronary heart disease. Curr. Opin. Lipidol. 7:217.
    • (1996) Curr. Opin. Lipidol , vol.7 , pp. 217
    • Laakso, M.1
  • 8
    • 0018775947 scopus 로고
    • Relationship of glucose tolerance and plasma insulin to the incidence of coronary heart disease: Results from two population studies in Finland
    • Pyorala K. 1979. Relationship of glucose tolerance and plasma insulin to the incidence of coronary heart disease: results from two population studies in Finland. Diabetes Care 2:131.
    • (1979) Diabetes Care , vol.2 , pp. 131
    • Pyorala, K.1
  • 9
    • 0025331112 scopus 로고
    • Insulin and atheroma. 20-yr perspective
    • Stout R.W. 1990. Insulin and atheroma. 20-yr perspective. Diabetes Care 13:631.
    • (1990) Diabetes Care , vol.13 , pp. 631
    • Stout, R.W.1
  • 12
    • 0038809142 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance
    • Sartipy P. and D.J. Loskutoff. 2003. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc. Natl. Acad. Scei. USA 100:7265.
    • (2003) Proc. Natl. Acad. Scei. USA , vol.100 , pp. 7265
    • Sartipy, P.1    Loskutoff, D.J.2
  • 13
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G., F.H. Nystrom, L.V. Ravichandran, L.N. Cong, M. Kirby, H. Mostowski and M.J. Quon. 2000. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101:1539.
    • (2000) Circulation , vol.101 , pp. 1539
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.N.4    Kirby, M.5    Mostowski, H.6    Quon, M.J.7
  • 14
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
    • Zeng G. and M.J. Quon. 1996. Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. J. Clin. Invest. 98:894.
    • (1996) J. Clin. Invest , vol.98 , pp. 894
    • Zeng, G.1    Quon, M.J.2
  • 15
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R., P. Libby, H.B. Peng, V.J. Thannickal, T.B. Rajavashisth, M.A. Gimbrone, Jr, W.S. Shin and J.K. Liao. 1995. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J. Clin. Invest. 96:60.
    • (1995) J. Clin. Invest , vol.96 , pp. 60
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone Jr, M.A.6    Shin, W.S.7    Liao, J.K.8
  • 16
    • 0036597085 scopus 로고    scopus 로고
    • The anti-inflammatory and potential anti-atherogenic effect of insulin: A new paradigm
    • Dandona P., A. Aljada and P. Mohanty. 2002. The anti-inflammatory and potential anti-atherogenic effect of insulin: a new paradigm. Diabetologia 45:924.
    • (2002) Diabetologia , vol.45 , pp. 924
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3
  • 17
    • 1842844426 scopus 로고    scopus 로고
    • Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase
    • Madonna R., A. Pandolfi, M. Massaro, A. Consoli and R. De Caterina. 2004. Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase. Diabetologia 47:532.
    • (2004) Diabetologia , vol.47 , pp. 532
    • Madonna, R.1    Pandolfi, A.2    Massaro, M.3    Consoli, A.4    De Caterina, R.5
  • 20
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han J., J.D. Lee, L. Bibbs and R.J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808.
    • (1994) Science , vol.265 , pp. 808
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 21
    • 0034660627 scopus 로고    scopus 로고
    • Regulation of TNF expression by multiple mitogen-activated protein kinase pathways
    • Zhu W., J.S. Downey, J. Gu, F. Di Padova, H. Gram and J. Han. 2000. Regulation of TNF expression by multiple mitogen-activated protein kinase pathways. J. Immunol. 164:6349.
    • (2000) J. Immunol , vol.164 , pp. 6349
    • Zhu, W.1    Downey, J.S.2    Gu, J.3    Di Padova, F.4    Gram, H.5    Han, J.6
  • 22
    • 1942521356 scopus 로고    scopus 로고
    • Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells
    • Viemann D., M. Goebeler, S. Schmid, K. Klimmek, C. Sorg, S. Ludwig and J. Roth. 2004. Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells. Blood 103:3365.
    • (2004) Blood , vol.103 , pp. 3365
    • Viemann, D.1    Goebeler, M.2    Schmid, S.3    Klimmek, K.4    Sorg, C.5    Ludwig, S.6    Roth, J.7
  • 23
    • 26844462934 scopus 로고    scopus 로고
    • Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro
    • Kuldo J.M., J. Westra, S.A. Asgeirsdottir, R.J. Kok, K. Oosterhuis, M.G. Rots, J.P. Schouten, P.C. Limburg and G. Molema. 2005. Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro. Am. J. Physiol. Cell Physiol. 289:C1229.
    • (2005) Am. J. Physiol. Cell Physiol , vol.289
    • Kuldo, J.M.1    Westra, J.2    Asgeirsdottir, S.A.3    Kok, R.J.4    Oosterhuis, K.5    Rots, M.G.6    Schouten, J.P.7    Limburg, P.C.8    Molema, G.9
  • 24
    • 17644383381 scopus 로고    scopus 로고
    • The subendothelial extracellular matrix modulates NF-kappaB activation by flow: A potential role in atherosclerosis
    • Orr A.W., J.M. Sanders, M. Bevard, E. Coleman, I.J. Sarembock and M.A. Schwartz. 2005. The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis. J. Cell Biol. 169:191.
    • (2005) J. Cell Biol , vol.169 , pp. 191
    • Orr, A.W.1    Sanders, J.M.2    Bevard, M.3    Coleman, E.4    Sarembock, I.J.5    Schwartz, M.A.6
  • 25
    • 21844438685 scopus 로고    scopus 로고
    • Proinflammatory activation of macrophages by basic calcium phosphate crystals via protein kinase C and MAP kinase pathways: A vicious cycle of inflammation and arterial calcification?
    • Nadra I., J.C. Mason, P. Philippidis, O. Florey, C.D. Smythe, G.M. McCarthy, R.C. Landis and D.O. Haskard. 2005. Proinflammatory activation of macrophages by basic calcium phosphate crystals via protein kinase C and MAP kinase pathways: a vicious cycle of inflammation and arterial calcification? Circ. Res. 96:1248.
    • (2005) Circ. Res , vol.96 , pp. 1248
    • Nadra, I.1    Mason, J.C.2    Philippidis, P.3    Florey, O.4    Smythe, C.D.5    McCarthy, G.M.6    Landis, R.C.7    Haskard, D.O.8
  • 26
    • 33644762891 scopus 로고    scopus 로고
    • Migration inhibitory factor up-regulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 via Src, PI3 kinase, and NFkappaB
    • Amin M.A., C.S. Haas, K. Zhu, P.J. Mansfield, M.J. Kim, N.P. Lackowski and A.E. Koch. 2006. Migration inhibitory factor up-regulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 via Src, PI3 kinase, and NFkappaB. Blood 107:2252.
    • (2006) Blood , vol.107 , pp. 2252
    • Amin, M.A.1    Haas, C.S.2    Zhu, K.3    Mansfield, P.J.4    Kim, M.J.5    Lackowski, N.P.6    Koch, A.E.7
  • 27
    • 0028278931 scopus 로고
    • The insulin receptor: Structure, function, and signaling
    • Lee J. and P.F. Pilch. 1994. The insulin receptor: structure, function, and signaling. Am. J. Physiol. 266:C319.
    • (1994) Am. J. Physiol , vol.266
    • Lee, J.1    Pilch, P.F.2
  • 28
    • 0030426902 scopus 로고    scopus 로고
    • Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
    • Badger A.M., J.N. Bradbeer, B. Votta, J.C. Lee, J.L. Adams and D.E. Griswold. 1996. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J. Pharmacol. Exp. Then 279:1453.
    • (1996) J. Pharmacol. Exp. Then , vol.279 , pp. 1453
    • Badger, A.M.1    Bradbeer, J.N.2    Votta, B.3    Lee, J.C.4    Adams, J.L.5    Griswold, D.E.6
  • 29
    • 0141431027 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha: A potential target for the therapy of solid tumours
    • Szlosarek P.W. and F.R. Balkwill. 2003. Tumour necrosis factor alpha: a potential target for the therapy of solid tumours. Lancet Oncol. 4:565.
    • (2003) Lancet Oncol , vol.4 , pp. 565
    • Szlosarek, P.W.1    Balkwill, F.R.2
  • 30
    • 0032559831 scopus 로고    scopus 로고
    • Expression and regulation of adhesion molecules in cardiac cells by cytokines: Response to acute hypoxia
    • Kacimi R., J.S. Karliner, F. Koudssi and C.S. Long. 1998. Expression and regulation of adhesion molecules in cardiac cells by cytokines: response to acute hypoxia. Circ. Res. 82:576.
    • (1998) Circ. Res , vol.82 , pp. 576
    • Kacimi, R.1    Karliner, J.S.2    Koudssi, F.3    Long, C.S.4
  • 31
    • 0036878373 scopus 로고    scopus 로고
    • p38 kinase and c-Jun N-terminal kinase oppositely regulates tumor necrosis factor alpha-induced vascular cell adhesion molecule-1 expression and cell adhesion in chondrosarcoma cells
    • Ju J.W., S.J. Kim, C.D. Jun and J.S. Chun. 2002. p38 kinase and c-Jun N-terminal kinase oppositely regulates tumor necrosis factor alpha-induced vascular cell adhesion molecule-1 expression and cell adhesion in chondrosarcoma cells. IUBMB Life 54:293.
    • (2002) IUBMB Life , vol.54 , pp. 293
    • Ju, J.W.1    Kim, S.J.2    Jun, C.D.3    Chun, J.S.4
  • 32
    • 0033623538 scopus 로고    scopus 로고
    • Protein kinase calpha but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH(2)-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1beta: Involvement of sequential activation of tyrosine kinase, nuclear factor-kappaB-inducing kinase, and IkappaB kinase 2
    • Chen C.C., J.J. Chen and C.Y. Chou. 2000. Protein kinase calpha but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH(2)-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1beta: involvement of sequential activation of tyrosine kinase, nuclear factor-kappaB-inducing kinase, and IkappaB kinase 2. Mol. Pharmacol. 58:1479.
    • (2000) Mol. Pharmacol , vol.58 , pp. 1479
    • Chen, C.C.1    Chen, J.J.2    Chou, C.Y.3
  • 33
    • 0034900321 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway
    • Chen C., C. Chou, Y. Sun and W. Huang. 2001. Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway. Cell Signal. 13:543.
    • (2001) Cell Signal , vol.13 , pp. 543
    • Chen, C.1    Chou, C.2    Sun, Y.3    Huang, W.4
  • 34
    • 13244259154 scopus 로고    scopus 로고
    • Redox regulation of p38 MAPK activation and expression of ICAM-1 and heme oxygenase-1 in human alveolar epithelial (A549) cells
    • Bundy R.E., G.S. Hoare, A. Kite, J. Beach, M. Yacoub and N. Marczin. 2005. Redox regulation of p38 MAPK activation and expression of ICAM-1 and heme oxygenase-1 in human alveolar epithelial (A549) cells. Antioxid. Redox Signal. 7:14.
    • (2005) Antioxid. Redox Signal , vol.7 , pp. 14
    • Bundy, R.E.1    Hoare, G.S.2    Kite, A.3    Beach, J.4    Yacoub, M.5    Marczin, N.6
  • 35
    • 0034928727 scopus 로고    scopus 로고
    • Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase
    • Rahman A., K.N. Anwar, S. Uddin, N. Xu, R.D. Ye, L.C. Platanias and A.B. Malik. 2001. Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase. Mol. Cell Biol. 21:5554.
    • (2001) Mol. Cell Biol , vol.21 , pp. 5554
    • Rahman, A.1    Anwar, K.N.2    Uddin, S.3    Xu, N.4    Ye, R.D.5    Platanias, L.C.6    Malik, A.B.7
  • 37
    • 33846027057 scopus 로고    scopus 로고
    • Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants
    • Hyduk S.J., J.R. Chan, S.T. Duffy, M. Chen, M.D. Peterson, T.K. Waddell, G.C. Digby, K. Szaszi, A. Kapus and M.I. Cybulsky. 2007. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood 109:176.
    • (2007) Blood , vol.109 , pp. 176
    • Hyduk, S.J.1    Chan, J.R.2    Duffy, S.T.3    Chen, M.4    Peterson, M.D.5    Waddell, T.K.6    Digby, G.C.7    Szaszi, K.8    Kapus, A.9    Cybulsky, M.I.10
  • 38
    • 14644404343 scopus 로고    scopus 로고
    • Role of p38 MAP kinase in postcapillary venule leukocyte adhesion induced by ischemia/reperfusion injury
    • Johns D.G., Z. Ao, R.N. Willette, C.H. Macphee and S.A. Douglas. 2005. Role of p38 MAP kinase in postcapillary venule leukocyte adhesion induced by ischemia/reperfusion injury. Pharmacol. Res. 51:463.
    • (2005) Pharmacol. Res , vol.51 , pp. 463
    • Johns, D.G.1    Ao, Z.2    Willette, R.N.3    Macphee, C.H.4    Douglas, S.A.5
  • 39
    • 2442473903 scopus 로고    scopus 로고
    • Negative regulation of the protein kinase C activator-induced ICAM-1 expression in the human bronchial epithelial cell line NCI-H292 by p44/42 mitogen-activated protein kinase
    • Shibuya Y., N. Hirasawa, T. Sakai, Y. Togashi, R. Muramatsu, K. Ishii, M. Yamashita, M. Takayanagi and K. Ohuchi. 2004. Negative regulation of the protein kinase C activator-induced ICAM-1 expression in the human bronchial epithelial cell line NCI-H292 by p44/42 mitogen-activated protein kinase. Life Sci. 75:435.
    • (2004) Life Sci , vol.75 , pp. 435
    • Shibuya, Y.1    Hirasawa, N.2    Sakai, T.3    Togashi, Y.4    Muramatsu, R.5    Ishii, K.6    Yamashita, M.7    Takayanagi, M.8    Ohuchi, K.9
  • 40
    • 0141506872 scopus 로고    scopus 로고
    • Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo
    • Yamawaki H., S. Lehoux and B.C. Berk. 2003. Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo. Circulation 108:1619.
    • (2003) Circulation , vol.108 , pp. 1619
    • Yamawaki, H.1    Lehoux, S.2    Berk, B.C.3
  • 41
    • 0033764665 scopus 로고    scopus 로고
    • Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB
    • Aggarwal B.B. 2000. Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. Ann. Rheum. Dis. 59(S):6.
    • (2000) Ann. Rheum. Dis , vol.59 , Issue.S , pp. 6
    • Aggarwal, B.B.1
  • 42
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis J.M. and J. Avruch. 2001. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:807.
    • (2001) Physiol. Rev , vol.81 , pp. 807
    • Kyriakis, J.M.1    Avruch, J.2
  • 43
    • 0034773951 scopus 로고    scopus 로고
    • Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells
    • Bian Z.M., S.G. Einer, A. Yoshida, S.L. Kunkel, J. Su and V.M. Einer. 2001. Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells. Exp. Eye Res. 73:111.
    • (2001) Exp. Eye Res , vol.73 , pp. 111
    • Bian, Z.M.1    Einer, S.G.2    Yoshida, A.3    Kunkel, S.L.4    Su, J.5    Einer, V.M.6
  • 44
    • 12144275863 scopus 로고    scopus 로고
    • Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-kappaB in IL-1beta-induced VCAM-1 expression in human tracheal smooth muscle cells
    • Wang C.C., W.N. Lin, C.W. Lee, C.C. Lin, S.F. Luo, J.S. Wang and C.M. Yang. 2005. Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-kappaB in IL-1beta-induced VCAM-1 expression in human tracheal smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 288:227.
    • (2005) Am. J. Physiol. Lung Cell Mol. Physiol , vol.288 , pp. 227
    • Wang, C.C.1    Lin, W.N.2    Lee, C.W.3    Lin, C.C.4    Luo, S.F.5    Wang, J.S.6    Yang, C.M.7
  • 45
    • 0024375693 scopus 로고
    • Sequential changes in serum insulin concentration during development of non-insulin-dependent diabetes
    • Saad M.F., W.C. Knowler, D.J. Pettitt, R.G. Nelson, D.M. Mott and P.H. Bennett. 1989. Sequential changes in serum insulin concentration during development of non-insulin-dependent diabetes. Lancet 1:1356.
    • (1989) Lancet , vol.1 , pp. 1356
    • Saad, M.F.1    Knowler, W.C.2    Pettitt, D.J.3    Nelson, R.G.4    Mott, D.M.5    Bennett, P.H.6
  • 46
    • 0034721925 scopus 로고    scopus 로고
    • Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells
    • Golovchenko I., M.L. Goalstone, P. Watson, M. Brownlee and B. Draznin. 2000. Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells. Circ. Res. 87:746.
    • (2000) Circ. Res , vol.87 , pp. 746
    • Golovchenko, I.1    Goalstone, M.L.2    Watson, P.3    Brownlee, M.4    Draznin, B.5
  • 47
    • 0141866848 scopus 로고    scopus 로고
    • Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways
    • Wang C.C., I. Gurevich and B. Draznin. 2003. Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways. Diabetes 52:2562.
    • (2003) Diabetes , vol.52 , pp. 2562
    • Wang, C.C.1    Gurevich, I.2    Draznin, B.3
  • 48
    • 0029664650 scopus 로고    scopus 로고
    • Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms
    • Lee J.C. and P.R. Young. 1996. Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J. Leukoc. Biol. 59:152.
    • (1996) J. Leukoc. Biol , vol.59 , pp. 152
    • Lee, J.C.1    Young, P.R.2
  • 49
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies S.P., H. Reddy, M. Caivano and P. Cohen. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:95.
    • (2000) Biochem. J , vol.351 , pp. 95
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 50
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin J.A.S. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649.
    • (1996) Annu. Rev. Immunol , vol.14 , pp. 649
    • Baldwin, J.A.S.1
  • 51
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers
    • Collins T., M.A. Read, A.S. Neish, M.Z. Whitley, D. Thanos and T. Maniatis. 1995. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J. 9:899.
    • (1995) FASEB J , vol.9 , pp. 899
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 52
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
    • Palombella V.J., O.J. Rando, A.L. Goldberg and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell 78:773.
    • (1994) Cell , vol.78 , pp. 773
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 53
    • 0030004897 scopus 로고    scopus 로고
    • Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
    • Chen Z.J., L. Parent and T. Maniatis. 1996. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell 84:853.
    • (1996) Cell , vol.84 , pp. 853
    • Chen, Z.J.1    Parent, L.2    Maniatis, T.3
  • 54
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • Dandona P., A. Aljada, P. Mohanty, H. Ghanim, W. Hamouda, E. Assian and S. Ahmad. 2001. Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J. Clin. Endocrinol. Metab. 86:3257.
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 3257
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Hamouda, W.5    Assian, E.6    Ahmad, S.7
  • 56
    • 0034721766 scopus 로고    scopus 로고
    • Hyperinsulinemia and vascular dysfunction: The role of nuclear factor-kappaB, yet again
    • Schmidt A.M. and D.M. Stern. 2000. Hyperinsulinemia and vascular dysfunction: the role of nuclear factor-kappaB, yet again. Circ. Res. 87:722.
    • (2000) Circ. Res , vol.87 , pp. 722
    • Schmidt, A.M.1    Stern, D.M.2
  • 57
    • 0031985903 scopus 로고    scopus 로고
    • Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: Role of the p38 and p42/44 mitogen-activated protein kinases
    • Foey A.D., S.L. Parry, L.M. Williams, M. Feldmann, B.M. Foxwell and F.M. Brennan. 1998. Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: role of the p38 and p42/44 mitogen-activated protein kinases. J. Immunol. 160:920.
    • (1998) J. Immunol , vol.160 , pp. 920
    • Foey, A.D.1    Parry, S.L.2    Williams, L.M.3    Feldmann, M.4    Foxwell, B.M.5    Brennan, F.M.6
  • 58
    • 0031114081 scopus 로고    scopus 로고
    • Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: Regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels
    • Ridley S.H., S.J. Sarsfield, J.C. Lee, H.F. Bigg, T.E. Cawston, D.J. Taylor, D.L. DeWitt and J. Saklatvala. 1997. Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. J. Immunol. 158:3165.
    • (1997) J. Immunol , vol.158 , pp. 3165
    • Ridley, S.H.1    Sarsfield, S.J.2    Lee, J.C.3    Bigg, H.F.4    Cawston, T.E.5    Taylor, D.J.6    DeWitt, D.L.7    Saklatvala, J.8
  • 59
    • 0033050497 scopus 로고    scopus 로고
    • Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. The Insulin Resistance Atherosclerosis Study (IRAS)
    • Festa A., R. D'Agostino Jr, L. Mykkanen, R.P. Tracy, D.J. Zaccaro, C.N. Hales and S.M. Haffner. 1999. Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. The Insulin Resistance Atherosclerosis Study (IRAS). Arterioscler. Thromb. Vasc. Biol. 19:562.
    • (1999) Arterioscler. Thromb. Vasc. Biol , vol.19 , pp. 562
    • Festa, A.1    D'Agostino Jr, R.2    Mykkanen, L.3    Tracy, R.P.4    Zaccaro, D.J.5    Hales, C.N.6    Haffner, S.M.7
  • 60
    • 0030256275 scopus 로고    scopus 로고
    • Insulin and the vasculature - old actors, new roles
    • Baron A.D. 1996. Insulin and the vasculature - old actors, new roles. J. Investig. Med. 44:406.
    • (1996) J. Investig. Med , vol.44 , pp. 406
    • Baron, A.D.1


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