Role of p38 MAP kinase in postcapillary venule leukocyte adhesion induced by ischemia/reperfusion injury

Pharmacological Research

Volumn 51, Issue 5, 2005, Pages 463-471

  Johns, Douglas G ^a   Ao, Zhaohui ^a   Willette, Robert N ^a   Macphee, Colin H ^a   Douglas, Stephen A ^a  

^a UW2510   (United States)

Author keywords

Intravital microscopy; Ischemia reperfusion injury; Leukocyte adhesion; Leukocyte migration; p38 MAP kinase

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL] CYCLOHEXANOL; 4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; DEXAMETHASONE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FLUORESCENT DYE; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PADGEM PROTEIN; RHODAMINE 6G; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LABELING; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; IN VIVO STUDY; ISCHEMIA; LEUKOCYTE; LEUKOCYTE ADHERENCE; LEUKOCYTE ROLLING; MALE; MONITORING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; VENULE;

EID: 14644404343     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phrs.2004.11.008     Document Type: Article

References (29)

1. S. Baez An open cremaster muscle preparation for the study of blood vessels by in vivo microscopy Microvasc Res 5 1973 384 394
2. F.C. Barone, E.A. Irving, A.M. Ray, J.C. Lee, S. Kassis, and S. Kumar Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia Med Res Rev 21 2001 129 145
3. S.A. Briaud, Z.M. Ding, L.H. Michael, M.L. Entman, S. Daniel, and C.M. Ballantyne Leukocyte trafficking and myocardial reperfusion injury in ICAM-1/P-selectin-knockout mice Am J Physiol 280 2001 H60 H67
4. D.C. Cara, J. Kaur, M. Forster, D-M. McCafferty, and P. Kubes Role of p38 mitogen-activated protein kinase in chemokine-induced emigration and chemotaxis in vivo J Immunol 167 2001 6552 6558
5. W.S. Colucci Molecular and cellular mechanisms of myocardial failure Am J Cardiol 80 1997 15L 25L
6. K. Ebnet, and D. Vestweber Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines Histochem Cell Biol 1 1999 1 23
7. J. Eder Tumour necrosis factor alpha and interleukin 1 signaling: do MAPK kinases connect it all? Trends Pharmacol Sci 18 1997 319 322
8. 4 integrin in cytokine-induced leukocyte endothelium interactions in the mouse aorta Circ Res 86 2000 526 533
9. N.G. Frangogiannis, C.W. Smith, and M.L. Entman The inflammatory response in myocardial infarction Cardiovasc Res 53 2002 31 47
10. M.A. Gaballa, and S. Goldman Ventricular remodeling in heart failure J Card Fail 8 2002 S476 S485
11. F. Gao, T-L. Yue, D-W. Shi, T.A. Christopher, B.L. Lopez, and E.H. Ohlstein p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation Cardiovasc Res 53 2002 414 422
12. E-B. Haddad, M. Birrell, K. McCluskie, A. Ling, S.E. Webber, and M.L. Foster Role of p38 MAP kinase in LPS-induced airway inflammation in the rat Br J Pharmacol 132 2001 1715 1724
13. E. Herlaar, and Z. Brown p38 MAPK signalling cascades in inflammatory disease Mol Med Today 5 1999 439 447
14. U. Jung, and K. Ley Regulation of E-selectin, P-selectin, and intercellular adhesion molecule 1 expression in mouse cremaster muscle vasculature Microcirculation 4 1997 311 319
15. J. Kaur, R.C. Woodman, and P. Kubes p38 MAPK: critical molecule in thrombin-induced NF-κB-dependent leukocyte recruitment Am J Physiol 284 2003 H1095 H1103
16. C.F. Krieglstein, and D.N. Granger Adhesion molecules and their role in vascular disease Am J Hypertens 6 2001 44S 54S
17. E.J. Kunkel, U. Jung, and K. Ley TNF-alpha induces selectin-mediated leukocyte rolling in mouse cremaster muscle arterioles Am J Physiol 272 1997 H1391 H1400
18. L.A. Lasky Selectins: interpreters of cell-specific carbohydrate information during inflammation Science 258 1992 964 969
19. K. Ley Molecular mechanisms of leukocyte recruitment in the inflammatory process Cardiovasc Res 32 1996 733 742
20. P. Libby Inflammation in atherosclerosis Nature 420 2002 868 874
21. H.H. Lipowsky, and B.W. Zweifach Application of the "two-slit" photometric technique to the measurement of microvascular volumetric flow rates Microvasc Res 15 1978 93 110
22. F.W. Luscinskas, and J. Lawler Integrins as dynamic regulators of vascular function FASEB J 8 1994 929 938
23. J.A. Nick, S.K. Young, P.G. Arndt, J.G. Lieber, B.T. Suratt, and K.R. Poch Selective suppression of neutrophil accumulation in ongoing pulmonary inflammation by systemic inhibtion of p38 mitogen-activated protein kinase J Immunol 169 2002 5260 5269
24. A.J. Prorock, A. Hafezi-Moghadam, V.E. Laubach, J.K. Liao, and K. Ley Vascular protection by estrogen in ischemia-reperfusion injury requires endothelial nitric oxide synthase Am J Physiol 284 2003 H133 H140
25. M. Redlin, J. Werner, H. Habazettl, W. Griethe, H. Kuppe, and A.R. Pries Cariporide (HOE 642) attenuates leukocyte activation in ischemia and reperfusion Anesth Analg 93 2001 1471 1479
26. R.B. Reneman Woldhuis, M. oude-Egbrink, D. Slaaf, and G. Tangelder Concentration and velocity profiles of blood cells in the microcirculation N. Hwang V. Turitto M. Yen Advances in cardiovascular engineering 1993 Plenum Press New York 25 40
27. R. Ross Atherosclerosis - an inflammatory disease N Engl J Med 340 1999 115 126
28. M. Suematsu, H. Suzuki, F.A. Delano, and G.W. Schmid-Schonbein The inflammatory aspect of the microcirculation in hypertension: oxidative stress, leukocytes/endothelial interaction, apoptosis Microcirculation 9 2002 259 276
29. X.W. Zhang, G. Hedlund, P. Borgstrom, K.E. Arfors, and H. Thorlacius Linomide abolishes leukocyte adhesion and extravascular recruitment induced by tumor necrosis factor α in vivo J Leukoc Biol 68 2000 621 626