Phospholipase C, calcium, and calmodulin are critical for α4β1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants

Blood

Volumn 109, Issue 1, 2007, Pages 176-184

  Hyduk, Sharon J ^a,b   Chan, Jason R ^a,b   Duffy, Stewart T ^a,b   Chen, Mian ^a,b   Peterson, Mark D ^a,b   Waddell, Thomas K ^a,b   Digby, Genevieve C ^a,b   Szaszi, Katalin ^a,b   Kapus, Andras ^a,b   Cybulsky, Myron I ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c TMDT   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; CALCIUM; CALCIUM ION; CALMODULIN; CHEMOATTRACTANT; CHEMOKINE; FLUORESCEIN ISOTHIOCYANATE; FORMYL METHIONYLLEUCYLPHENYLALANINE; FORMYLPEPTIDE RECEPTOR; G PROTEIN COUPLED RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHENYLALANINE DERIVATIVE; PHORBOL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE C; STROMAL CELL DERIVED FACTOR 1ALPHA; THAPSIGARGIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CELL STRAIN U937; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKOCYTE; LIGAND BINDING; MONOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; UPREGULATION;

EID: 33846027057     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-01-029199     Document Type: Article

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