Structure and function of human erythrocyte pyruvate kinase: Molecular basis of nonspherocytic hemolytic anemia

Journal of Biological Chemistry

Volumn 277, Issue 26, 2002, Pages 23807-23814

  Valentini, Giovanna ^a   Chiarelli, Laurent R ^a   Fortin, Riccardo ^a,b   Dolzan, Manuela ^a   Galizzi, Alessandro ^a,b   Abraham, Donald J ^a,b   Wang, Changqing ^a   Bianchi, Paola ^a   Zanella, Alberto ^a   Mattevi, Andrea ^a,c  

^a UNIVERSITY OF PAVIA   (Italy)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR PROPERTIES;

CATALYSIS; CRYSTAL STRUCTURE; DISEASES; ENZYMES; GLUCOSE; MUTAGENESIS; SUBSTRATES;

BIOCHEMISTRY;

FRUCTOSE BISPHOSPHATE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLYCOLIC ACID DERIVATIVE; ISOENZYME; MUTANT PROTEIN; PYRUVATE KINASE;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISEASE SEVERITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; ERYTHROCYTE; ERYTHROCYTE METABOLISM; GENETIC COUNSELING; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMOLYTIC ANEMIA; MUTATION; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN FUNCTION; SYMPTOMATOLOGY; THERMOSTABILITY;

ALLOSTERIC REGULATION; ANEMIA, HEMOLYTIC, CONGENITAL NONSPHEROCYTIC; CATALYTIC DOMAIN; CRYSTALLOGRAPHY; ERYTHROCYTES; HUMANS; MUTAGENESIS; PROTEIN CONFORMATION; PYRUVATE KINASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18544366712     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202107200     Document Type: Article

References (38)