A new allosteric site in glycogen phosphorylase b as a target for drug interactions

Structure

Volumn 8, Issue 6, 2000, Pages 575-584

  Oikonomakos, Nikos G ^a   Skamnaki, Vicky T ^a   Tsitsanou, Katerina E ^a   Gavalas, Nikos G ^a   Johnson, Louise N ^b  

^a INSTITUTE OF BIOLOGY   (Greece)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Allosteric inhibition; Diabetes; Glycogen metabolism; Glycogen phosphorylase; Protein drug interactions

Indexed keywords

5 CHLORO 1H INDOLE 2 CARBOXYLIC ACID (1 (4 FLUOROBENZYL) 2 (4 HYDROXYPIPERIDIN 1 YL) 2 OXOETHYL)AMIDE; CP 320626; ENZYME INHIBITOR; GLYCOGEN PHOSPHORYLASE B; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; BINDING SITE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; GLYCOGENOLYSIS; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0034660681     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00144-1     Document Type: Article

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