메뉴 건너뛰기




Volumn 27, Issue 18, 2007, Pages 6532-6545

Mdt1 facilitates efficient repair of blocked DNA double-strand breaks and recombinational maintenance of telomeres

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CAMPTOTHECIN; CHECKPOINT KINASE 2; DNA BINDING PROTEIN; ENDONUCLEASE; PROTEIN MDT1; UNCLASSIFIED DRUG;

EID: 34548798676     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00471-07     Document Type: Article
Times cited : (14)

References (75)
  • 1
    • 0842282564 scopus 로고    scopus 로고
    • A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin
    • Aouida, M., N. Page, A. Leduc, M. Peter, and D. Ramotar. 2004. A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin. Cancer Res. 64:1102-1109.
    • (2004) Cancer Res , vol.64 , pp. 1102-1109
    • Aouida, M.1    Page, N.2    Leduc, A.3    Peter, M.4    Ramotar, D.5
  • 2
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • Aylon, Y., B. Liefshitz, and M. Kupiec. 2004. The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J. 23:4868-4875.
    • (2004) EMBO J , vol.23 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3
  • 3
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton, S. J., and S. P. Jackson. 1998. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17:1819-1828.
    • (1998) EMBO J , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 4
    • 0037716757 scopus 로고    scopus 로고
    • Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
    • Chan, S. W., and E. H. Blackburn. 2003. Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol. Cell 11:1379-1387.
    • (2003) Mol. Cell , vol.11 , pp. 1379-1387
    • Chan, S.W.1    Blackburn, E.H.2
  • 5
    • 13444257678 scopus 로고    scopus 로고
    • Bleomycins: Towards better therapeutics
    • Chen, J., and J. Stubbe. 2005. Bleomycins: towards better therapeutics. Nat. Rev. Cancer 5:102-112.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 102-112
    • Chen, J.1    Stubbe, J.2
  • 6
    • 0035131699 scopus 로고    scopus 로고
    • Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events
    • Chen, Q., A. Ijpma, and C. W. Greider. 2001. Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol. Cell. Biol. 21:1819-1827.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 1819-1827
    • Chen, Q.1    Ijpma, A.2    Greider, C.W.3
  • 7
    • 21644449682 scopus 로고    scopus 로고
    • Def1p is involved in telomere maintenance in budding yeast
    • Chen, Y. B., C. P. Yang, R. X. Li, R. Zeng, and J. Q. Zhou. 2005. Def1p is involved in telomere maintenance in budding yeast. J. Biol. Chem. 280:24784-24791.
    • (2005) J. Biol. Chem , vol.280 , pp. 24784-24791
    • Chen, Y.B.1    Yang, C.P.2    Li, R.X.3    Zeng, R.4    Zhou, J.Q.5
  • 8
    • 27944503931 scopus 로고    scopus 로고
    • Inactivation of Ku-mediated end joining suppresses mec1Δ lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex
    • Corda, Y., S. E. Lee, S. Guillot, A. Walther, J. Sollier, A. Arbel-Eden, J. E. Haber, and V. Geli. 2005. Inactivation of Ku-mediated end joining suppresses mec1Δ lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex. Mol. Cell. Biol. 25:10652-10664.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 10652-10664
    • Corda, Y.1    Lee, S.E.2    Guillot, S.3    Walther, A.4    Sollier, J.5    Arbel-Eden, A.6    Haber, J.E.7    Geli, V.8
  • 9
    • 33646194957 scopus 로고    scopus 로고
    • Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae
    • Cost, G. J., and N. R. Cozzarelli. 2006. Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae. Genetics 172:2185-2200.
    • (2006) Genetics , vol.172 , pp. 2185-2200
    • Cost, G.J.1    Cozzarelli, N.R.2
  • 10
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • de Lange, T. 2005. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19:2100-2110.
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 11
    • 0036677405 scopus 로고    scopus 로고
    • MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae
    • Enomoto, S., L. Glowczewski, and J. Berman. 2002. MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae. Mol. Biol. Cell 13:2626-2638.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2626-2638
    • Enomoto, S.1    Glowczewski, L.2    Berman, J.3
  • 12
    • 0037277456 scopus 로고    scopus 로고
    • Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae
    • Enyenihi, A. H., and W. S. Saunders. 2003. Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae. Genetics 163:47-54.
    • (2003) Genetics , vol.163 , pp. 47-54
    • Enyenihi, A.H.1    Saunders, W.S.2
  • 13
    • 16844371495 scopus 로고    scopus 로고
    • Telomerase-independent telomere length maintenance in the absence of alternative lengthening of telomeres-associated promyelocytic leukemia bodies
    • Fasching, C. L., K. Bower, and R. R. Reddel. 2005. Telomerase-independent telomere length maintenance in the absence of alternative lengthening of telomeres-associated promyelocytic leukemia bodies. Cancer Res. 65:2722-2729.
    • (2005) Cancer Res , vol.65 , pp. 2722-2729
    • Fasching, C.L.1    Bower, K.2    Reddel, R.R.3
  • 14
    • 0037050026 scopus 로고    scopus 로고
    • Gavin, A. C., M. Bosche, R. Krause, P. Grandi, M. Marzioch, A. Bauer, J. Schultz, J. M. Rick, A. M. Michon, C. M. Cruciat, M. Remor, C. Hofert, M. Schelder, M. Brajenovic, H. Ruffner, A. Merino, K. Klein, M. Hudak, D. Dickson, T. Rudi, V. Gnau, A. Bauch, S. Bastuck, B. Huhse, C. Leutwein, M. A. Heurtier, R. R. Copley, A. Edelmann, E. Querfurth, V. Rybin, G. Drewes, M. Raida, T. Bouwmeester, P. Bork, B. Seraphin, B. Kuster, G. Neubauer, and G. Superti-Furga. 2002. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415:141-147.
    • Gavin, A. C., M. Bosche, R. Krause, P. Grandi, M. Marzioch, A. Bauer, J. Schultz, J. M. Rick, A. M. Michon, C. M. Cruciat, M. Remor, C. Hofert, M. Schelder, M. Brajenovic, H. Ruffner, A. Merino, K. Klein, M. Hudak, D. Dickson, T. Rudi, V. Gnau, A. Bauch, S. Bastuck, B. Huhse, C. Leutwein, M. A. Heurtier, R. R. Copley, A. Edelmann, E. Querfurth, V. Rybin, G. Drewes, M. Raida, T. Bouwmeester, P. Bork, B. Seraphin, B. Kuster, G. Neubauer, and G. Superti-Furga. 2002. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415:141-147.
  • 15
    • 0344197749 scopus 로고    scopus 로고
    • Mitotic cyclins regulate telomeric recombination in telomerase-deficient yeast cells
    • Grandin, N., and M. Charbonneau. 2003. Mitotic cyclins regulate telomeric recombination in telomerase-deficient yeast cells. Mol. Cell. Biol. 23:9162-9177.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 9162-9177
    • Grandin, N.1    Charbonneau, M.2
  • 16
    • 0035502994 scopus 로고    scopus 로고
    • Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
    • Grandin, N., C. Damon, and M. Charbonneau. 2001. Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J. 20:6127-6139.
    • (2001) EMBO J , vol.20 , pp. 6127-6139
    • Grandin, N.1    Damon, C.2    Charbonneau, M.3
  • 17
    • 18944387709 scopus 로고    scopus 로고
    • Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles
    • Groff-Vindman, C., A. J. Cesare, S. Natarajan, J. D. Griffith, and M. J. McEachern. 2005. Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles. Mol. Cell. Biol. 25:4406-4412.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 4406-4412
    • Groff-Vindman, C.1    Cesare, A.J.2    Natarajan, S.3    Griffith, J.D.4    McEachern, M.J.5
  • 18
    • 0034195218 scopus 로고    scopus 로고
    • Partners and pathways repairing a double-strand break
    • Haber, J. E. 2000. Partners and pathways repairing a double-strand break. Trends Genet. 16:259-264.
    • (2000) Trends Genet , vol.16 , pp. 259-264
    • Haber, J.E.1
  • 20
    • 0035051062 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion
    • Hanna, J. S., E. S. Kroll, V. Lundblad, and F. A. Spencer. 2001. Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion. Mol. Cell. Biol. 21:3144-3158.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 3144-3158
    • Hanna, J.S.1    Kroll, E.S.2    Lundblad, V.3    Spencer, F.A.4
  • 21
    • 33645739139 scopus 로고    scopus 로고
    • Hiraga, S., E. D. Robertson, and A. D. Donaldson. 2006. The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J. 25:1505-1514.
    • Hiraga, S., E. D. Robertson, and A. D. Donaldson. 2006. The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J. 25:1505-1514.
  • 23
    • 0345447604 scopus 로고    scopus 로고
    • Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast
    • Ira, G., A. Malkova, G. Liberi, M. Foiani, and J. E. Haber. 2003. Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell 115:401-411.
    • (2003) Cell , vol.115 , pp. 401-411
    • Ira, G.1    Malkova, A.2    Liberi, G.3    Foiani, M.4    Haber, J.E.5
  • 27
    • 10344263324 scopus 로고    scopus 로고
    • Recombination proteins in yeast
    • Krogh, B. O., and L. S. Symington. 2004. Recombination proteins in yeast. Annu. Rev. Genet. 38:233-271.
    • (2004) Annu. Rev. Genet , vol.38 , pp. 233-271
    • Krogh, B.O.1    Symington, L.S.2
  • 28
    • 33745744815 scopus 로고    scopus 로고
    • Telomerase- and capping-independent yeast survivors with alternate telomere states
    • Larrivee, M., and R. J. Wellinger. 2006. Telomerase- and capping-independent yeast survivors with alternate telomere states. Nat. Cell Biol. 8:741-747.
    • (2006) Nat. Cell Biol , vol.8 , pp. 741-747
    • Larrivee, M.1    Wellinger, R.J.2
  • 29
    • 0032959506 scopus 로고    scopus 로고
    • RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase
    • Le, S., J. K. Moore, J. E. Haber, and C. W. Greider. 1999. RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics 152:143-152.
    • (1999) Genetics , vol.152 , pp. 143-152
    • Le, S.1    Moore, J.K.2    Haber, J.E.3    Greider, C.W.4
  • 30
    • 0042470439 scopus 로고    scopus 로고
    • Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling
    • Lee, S. J., M. F. Schwartz, J. K. Duong, and D. F. Stern. 2003. Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol. Cell. Biol. 23:6300-6314.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 6300-6314
    • Lee, S.J.1    Schwartz, M.F.2    Duong, J.K.3    Stern, D.F.4
  • 31
    • 0344643062 scopus 로고    scopus 로고
    • PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break
    • Leroy, C., S. E. Lee, M. B. Vaze, F. Ochsenbien, R. Guerois, J. E. Haber, and M. C. Marsolier-Kergoat. 2003. PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break. Mol. Cell 11:827-835.
    • (2003) Mol. Cell , vol.11 , pp. 827-835
    • Leroy, C.1    Lee, S.E.2    Vaze, M.B.3    Ochsenbien, F.4    Guerois, R.5    Haber, J.E.6    Marsolier-Kergoat, M.C.7
  • 32
    • 13844311437 scopus 로고    scopus 로고
    • Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase delta-mediated telomere-telomere recombination in Saccharomyces cerevisiae
    • Lin, C. Y., H. H. Chang, K. J. Wu, S. F. Tseng, C. C. Lin, C. P. Lin, and S. C. Teng. 2005. Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase delta-mediated telomere-telomere recombination in Saccharomyces cerevisiae. Eukaryot. Cell 4:327-336.
    • (2005) Eukaryot. Cell , vol.4 , pp. 327-336
    • Lin, C.Y.1    Chang, H.H.2    Wu, K.J.3    Tseng, S.F.4    Lin, C.C.5    Lin, C.P.6    Teng, S.C.7
  • 33
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • Lisby, M., J. H. Barlow, R. C. Burgess, and R. Rothstein. 2004. Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118:699-713.
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 34
    • 6344254299 scopus 로고    scopus 로고
    • The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks
    • Llorente, B., and L. S. Symington. 2004. The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks. Mol. Cell. Biol. 24:9682-9694.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 9682-9694
    • Llorente, B.1    Symington, L.S.2
  • 36
    • 0043210729 scopus 로고    scopus 로고
    • Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae
    • Lowell, J. E., A. I. Roughton, V. Lundblad, and L. Pillus. 2003. Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae. Genetics 164:909-921.
    • (2003) Genetics , vol.164 , pp. 909-921
    • Lowell, J.E.1    Roughton, A.I.2    Lundblad, V.3    Pillus, L.4
  • 37
    • 0242468933 scopus 로고    scopus 로고
    • Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences
    • Ma, J. L., E. M. Kim, J. E. Haber, and S. E. Lee. 2003. Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol. Cell. Biol. 23:8820-8828.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 8820-8828
    • Ma, J.L.1    Kim, E.M.2    Haber, J.E.3    Lee, S.E.4
  • 39
    • 34047102946 scopus 로고    scopus 로고
    • Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks
    • Mantiero, D., M. Clerici, G. Lucchini, and M. P. Longhese. 2007. Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. EMBO Rep. 8:380-387.
    • (2007) EMBO Rep , vol.8 , pp. 380-387
    • Mantiero, D.1    Clerici, M.2    Lucchini, G.3    Longhese, M.P.4
  • 40
    • 2442515306 scopus 로고    scopus 로고
    • EXO1 plays a role in generating type I and type II survivors in budding yeast
    • Maringele, L., and D. Lydall. 2004. EXO1 plays a role in generating type I and type II survivors in budding yeast. Genetics 166:1641-1649.
    • (2004) Genetics , vol.166 , pp. 1641-1649
    • Maringele, L.1    Lydall, D.2
  • 41
    • 22744456546 scopus 로고    scopus 로고
    • ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage
    • McNees, C. J., L. A. Conlan, N. Tenis, and J. Heierhorst. 2005. ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage. EMBO J. 24:2447-2457.
    • (2005) EMBO J , vol.24 , pp. 2447-2457
    • McNees, C.J.1    Conlan, L.A.2    Tenis, N.3    Heierhorst, J.4
  • 42
    • 10944224673 scopus 로고    scopus 로고
    • INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair
    • Morrison, A. J., J. Highland, N. J. Krogan, A. Arbel-Eden, J. F. Greenblatt, J. E. Haber, and X. Shen. 2004. INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119:767-775.
    • (2004) Cell , vol.119 , pp. 767-775
    • Morrison, A.J.1    Highland, J.2    Krogan, N.J.3    Arbel-Eden, A.4    Greenblatt, J.F.5    Haber, J.E.6    Shen, X.7
  • 44
    • 23944459784 scopus 로고    scopus 로고
    • Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
    • Neale, M. J., J. Pan, and S. Keeney. 2005. Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature 436:1053-1057.
    • (2005) Nature , vol.436 , pp. 1053-1057
    • Neale, M.J.1    Pan, J.2    Keeney, S.3
  • 45
    • 33644778778 scopus 로고    scopus 로고
    • A DNA integrity network in the yeast Saccharomyces cerevisiae
    • Pan, X., P. Ye, D. S. Yuan, X. Wang, J. S. Bader, and J. D. Boeke. 2006. A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124:1069-1081.
    • (2006) Cell , vol.124 , pp. 1069-1081
    • Pan, X.1    Ye, P.2    Yuan, D.S.3    Wang, X.4    Bader, J.S.5    Boeke, J.D.6
  • 47
    • 33645093716 scopus 로고    scopus 로고
    • Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae
    • Pennaneach, V., C. D. Putnam, and R. D. Kolodner. 2006. Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae. Mol. Microbiol. 59:1357-1368.
    • (2006) Mol. Microbiol , vol.59 , pp. 1357-1368
    • Pennaneach, V.1    Putnam, C.D.2    Kolodner, R.D.3
  • 48
    • 0035957965 scopus 로고    scopus 로고
    • Role of the N-terminal forkhead-associated domain in the cell cycle checkpoint function of the Rad53 kinase
    • Pike, B. L., A. Hammet, and J. Heierhorst. 2001. Role of the N-terminal forkhead-associated domain in the cell cycle checkpoint function of the Rad53 kinase. J. Biol. Chem. 276:14019-14026.
    • (2001) J. Biol. Chem , vol.276 , pp. 14019-14026
    • Pike, B.L.1    Hammet, A.2    Heierhorst, J.3
  • 49
    • 4544319101 scopus 로고    scopus 로고
    • Rad53 kinase activation-independent replication checkpoint function of the N-terminal forkhead-associated (FHA1) domain
    • Pike, B. L., N. Tenis, and J. Heierhorst. 2004. Rad53 kinase activation-independent replication checkpoint function of the N-terminal forkhead-associated (FHA1) domain. J. Biol. Chem. 279:39636-39644.
    • (2004) J. Biol. Chem , vol.279 , pp. 39636-39644
    • Pike, B.L.1    Tenis, N.2    Heierhorst, J.3
  • 50
    • 0042734418 scopus 로고    scopus 로고
    • Diverse but overlapping functions of the two forkhead-associated (FHA) domains in Rad53 checkpoint kinase activation
    • Pike, B. L., S. Yongkiettrakul, M. D. Tsai, and J. Heierhorst. 2003. Diverse but overlapping functions of the two forkhead-associated (FHA) domains in Rad53 checkpoint kinase activation. J. Biol. Chem. 278:30421-30424.
    • (2003) J. Biol. Chem , vol.278 , pp. 30421-30424
    • Pike, B.L.1    Yongkiettrakul, S.2    Tsai, M.D.3    Heierhorst, J.4
  • 52
    • 0034871092 scopus 로고    scopus 로고
    • Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae
    • Pouliot, J. J., C. A. Rohertson, and H. A. Nash. 2001. Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae. Genes Cells 6:677-687.
    • (2001) Genes Cells , vol.6 , pp. 677-687
    • Pouliot, J.J.1    Rohertson, C.A.2    Nash, H.A.3
  • 53
    • 0038495946 scopus 로고    scopus 로고
    • Protective mechanisms against the antitumor agent bleomycin: Lessons from Saccharomyces cerevisiae
    • Ramotar, D., and H. Wang. 2003. Protective mechanisms against the antitumor agent bleomycin: lessons from Saccharomyces cerevisiae. Curr. Genet. 43:213-224.
    • (2003) Curr. Genet , vol.43 , pp. 213-224
    • Ramotar, D.1    Wang, H.2
  • 54
    • 0034437652 scopus 로고    scopus 로고
    • Recombination between two chromosomes: Implications for genomic integrity in mammalian cells
    • Richardson, C., and M. Jasin. 2000. Recombination between two chromosomes: implications for genomic integrity in mammalian cells. Cold Spring Harbor Symp. Quant. Biol. 65:553-560.
    • (2000) Cold Spring Harbor Symp. Quant. Biol , vol.65 , pp. 553-560
    • Richardson, C.1    Jasin, M.2
  • 55
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez, Y., B. A. Desany, W. J. Jones, Q. Liu, B. Wang, and S. J. Elledge. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271:357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 56
    • 18144423533 scopus 로고    scopus 로고
    • The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks
    • Shim, E. Y., J. L. Ma, J. H. Oum, Y. Yanez, and S. E. Lee. 2005. The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks. Mol. Cell. Biol. 25:3934-3944.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 3934-3944
    • Shim, E.Y.1    Ma, J.L.2    Oum, J.H.3    Yanez, Y.4    Lee, S.E.5
  • 57
    • 0141525391 scopus 로고    scopus 로고
    • Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
    • Stellwagen, A. E., Z. W. Haimberger, J. R. Veatch, and D. E. Gottschling. 2003. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev. 17:2384-2395.
    • (2003) Genes Dev , vol.17 , pp. 2384-2395
    • Stellwagen, A.E.1    Haimberger, Z.W.2    Veatch, J.R.3    Gottschling, D.E.4
  • 58
    • 2442595631 scopus 로고    scopus 로고
    • Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo
    • Takata, H., Y. Kanoh, N. Gunge, K. Shirahige, and A. Matsuura. 2004. Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo. Mol. Cell 14:515-522.
    • (2004) Mol. Cell , vol.14 , pp. 515-522
    • Takata, H.1    Kanoh, Y.2    Gunge, N.3    Shirahige, K.4    Matsuura, A.5
  • 59
    • 34247476056 scopus 로고    scopus 로고
    • Telomere-related functions of yeast KU in the repair of bleomycin-induced DNA damage
    • Tam, A. T., B. L. Pike, A. Hammet, and J. Heierhorst. 2007. Telomere-related functions of yeast KU in the repair of bleomycin-induced DNA damage. Biochem. Biophys. Res. Commun. 357:800-803.
    • (2007) Biochem. Biophys. Res. Commun , vol.357 , pp. 800-803
    • Tam, A.T.1    Pike, B.L.2    Hammet, A.3    Heierhorst, J.4
  • 60
    • 0033513079 scopus 로고    scopus 로고
    • Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae
    • Teng, S. C., and V. A. Zakian. 1999. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:8083-8093.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 8083-8093
    • Teng, S.C.1    Zakian, V.A.2
  • 61
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo, S. H., and S. P. Jackson. 1997. Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J. 16:4788-4795.
    • (1997) EMBO J , vol.16 , pp. 4788-4795
    • Teo, S.H.1    Jackson, S.P.2
  • 62
    • 31044432248 scopus 로고    scopus 로고
    • Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region
    • Therizols, P., C. Fairhead, G. G. Cabal, A. Genovesio, J. C. Olivo-Marin, B. Dujon, and E. Fabre. 2006. Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region. J. Cell Biol. 172:189-199.
    • (2006) J. Cell Biol , vol.172 , pp. 189-199
    • Therizols, P.1    Fairhead, C.2    Cabal, G.G.3    Genovesio, A.4    Olivo-Marin, J.C.5    Dujon, B.6    Fabre, E.7
  • 63
    • 10744230485 scopus 로고    scopus 로고
    • Tong, A. H., G. Lesage, G. D. Bader, H. Ding, H. Xu, X. Xin, J. Young, G. F. Berriz, R. L. Brost, M. Chang, Y. Chen, X. Cheng, G. Chua, H. Friesen, D. S. Goldberg, J. Haynes, C. Humphries, G. He, S. Hussein, L. Ke, N. Krogan, Z. Li, J. N. Levinson, H. Lu, P. Menard, C. Munyana, A. B. Parsons, O. Ryan, R. Tonikian, T. Roberts, A. M. Sdicu, J. Shapiro, B. Sheikh, B. Suter, S. L. Wong, L. V. Zhang, H. Zhu, C. G. Burd, S. Munro, C. Sander, J. Rine, J. Greenblatt, M. Peter, A. Bretscher, G. Bell, F. P. Roth, G. W. Brown, B. Andrews, H. Bussey, and C. Boone. 2004. Global mapping of the yeast genetic interaction network. Science 303:808-813.
    • Tong, A. H., G. Lesage, G. D. Bader, H. Ding, H. Xu, X. Xin, J. Young, G. F. Berriz, R. L. Brost, M. Chang, Y. Chen, X. Cheng, G. Chua, H. Friesen, D. S. Goldberg, J. Haynes, C. Humphries, G. He, S. Hussein, L. Ke, N. Krogan, Z. Li, J. N. Levinson, H. Lu, P. Menard, C. Munyana, A. B. Parsons, O. Ryan, R. Tonikian, T. Roberts, A. M. Sdicu, J. Shapiro, B. Sheikh, B. Suter, S. L. Wong, L. V. Zhang, H. Zhu, C. G. Burd, S. Munro, C. Sander, J. Rine, J. Greenblatt, M. Peter, A. Bretscher, G. Bell, F. P. Roth, G. W. Brown, B. Andrews, H. Bussey, and C. Boone. 2004. Global mapping of the yeast genetic interaction network. Science 303:808-813.
  • 64
    • 17844372453 scopus 로고    scopus 로고
    • SQ/TQ cluster domains: Concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins
    • Traven, A., and J. Heierhorst. 2005. SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins. BioEssays 27:297-307.
    • (2005) BioEssays , vol.27 , pp. 297-307
    • Traven, A.1    Heierhorst, J.2
  • 66
    • 0036311563 scopus 로고    scopus 로고
    • Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination
    • Tsai, Y. L., S. F. Tseng, S. H. Chang, C. C. Lin, and S. C. Teng. 2002. Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination. Mol. Cell. Biol. 22:5679-5687.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 5679-5687
    • Tsai, Y.L.1    Tseng, S.F.2    Chang, S.H.3    Lin, C.C.4    Teng, S.C.5
  • 67
    • 10944262393 scopus 로고    scopus 로고
    • DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
    • Unal, E., A. Arbel-Eden, U. Sattler, R. Shroff, M. Lichten, J. E. Haber, and D. Koshland. 2004. DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol. Cell 16:991-1002.
    • (2004) Mol. Cell , vol.16 , pp. 991-1002
    • Unal, E.1    Arbel-Eden, A.2    Sattler, U.3    Shroff, R.4    Lichten, M.5    Haber, J.E.6    Koshland, D.7
  • 68
    • 0034964498 scopus 로고    scopus 로고
    • A DNA damage response pathway controlled by Tel1 and the Mre11 complex
    • Usui, T., H. Ogawa, and J. H. Petrini. 2001. A DNA damage response pathway controlled by Tel1 and the Mre11 complex. Mol. Cell 7:1255-1266.
    • (2001) Mol. Cell , vol.7 , pp. 1255-1266
    • Usui, T.1    Ogawa, H.2    Petrini, J.H.3
  • 70
    • 33748885242 scopus 로고    scopus 로고
    • Different mating-type-regulated genes affect the DNA repair defects of Saccharomyces RAD51, RAD52 and RAD55 mutants
    • Valencia-Burton, M., M. Oki, J. Johnson, T. A. Seier, R. Kamakaka, and J. E. Haber. 2006. Different mating-type-regulated genes affect the DNA repair defects of Saccharomyces RAD51, RAD52 and RAD55 mutants. Genetics 174:41-55.
    • (2006) Genetics , vol.174 , pp. 41-55
    • Valencia-Burton, M.1    Oki, M.2    Johnson, J.3    Seier, T.A.4    Kamakaka, R.5    Haber, J.E.6
  • 71
    • 10944233962 scopus 로고    scopus 로고
    • Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
    • van Attikum, H., O. Fritsch, B. Hohn, and S. M. Gasser. 2004. Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell 119:777-788.
    • (2004) Cell , vol.119 , pp. 777-788
    • van Attikum, H.1    Fritsch, O.2    Hohn, B.3    Gasser, S.M.4
  • 72
    • 0345169051 scopus 로고    scopus 로고
    • Getting to the end: Telomerase access in yeast and humans
    • Vega, L. R., M. K. Mateyak, and V. A. Zakian. 2003. Getting to the end: telomerase access in yeast and humans. Nat. Rev. Mol. Cell Biol. 4:948-959.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 948-959
    • Vega, L.R.1    Mateyak, M.K.2    Zakian, V.A.3
  • 73
    • 0030811523 scopus 로고    scopus 로고
    • Yeast DNA ligase IV mediates non-homologous DNA end joining
    • Wilson, T. E., U. Grawunder, and M. R. Lieber. 1997. Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature 388:495-498.
    • (1997) Nature , vol.388 , pp. 495-498
    • Wilson, T.E.1    Grawunder, U.2    Lieber, M.R.3
  • 74
    • 0032161269 scopus 로고    scopus 로고
    • A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
    • Zhao, X., E. G. Muller, and R. Rothstein. 1998. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools. Mol. Cell 2:329-340.
    • (1998) Mol. Cell , vol.2 , pp. 329-340
    • Zhao, X.1    Muller, E.G.2    Rothstein, R.3
  • 75
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B. B., and S. J. Elledge. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408:433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.