Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion

Molecular and Cellular Biology

Volumn 21, Issue 9, 2001, Pages 3144-3158

  Hanna, J S ^a   Kroll, E S ^a   Lundblad, V ^a   Spencer, F A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS ANTIGEN; GENE PRODUCT; PROTEIN CTF18; PROTEIN CTF4; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CHROMOSOME SEGREGATION; COMPLEX FORMATION; DNA REPLICATION; ENZYME ANALYSIS; GENE REPLICATION; GENETIC CODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SISTER CHROMATID;

ANIMALS; CHROMATIDS; CHROMOSOMES, FUNGAL; DNA REPLICATION; DNA, FUNGAL; DNA, RIBOSOMAL; DNA-BINDING PROTEINS; EUKARYOTIC CELLS; FUNGAL PROTEINS; G2 PHASE; HOMEODOMAIN PROTEINS; HUMANS; MITOSIS; MITOTIC SPINDLE APPARATUS; MUTAGENESIS; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REPLICATION PROTEIN C; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES;

BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 0035051062     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.9.3144-3158.2001     Document Type: Article

References (120)

1. Dominant mutations in three different subunits of replication factor C suppress replication defects in yeast PCNA
2. Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase
3. DNA polymerase beta-like nucleotidyltransferase superfamily: Identification of three new families, classification and evolutionary history
4. A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair
5. Allele-specific interactions between the yeast RFC1 and RFC5 genes suggest a basis for RFC subunit-subunit interactions
6. The DIF1 gene of Arabidopsis is required for meiotic chromosome segregation and belongs to the REC8/RAD21 cohesion gene family
7. Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair
8. The rad21 gene product of Schizosaccharomyces pombe is a nuclear, cell cycle-regulated phosphoprotein
9. Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region
10. Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
11. A yeast replicative DNA helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function
12. Collisions between yeast chromosomal loci in vivo are governed by three layers of organization
13. Somatic pairing of homologs in budding yeast: Existence and modulation
14. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae
15. A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation
16. Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins
17. Characterization of the fivereplication factor C genes of Saccharomyces cerevisiae
18. Characterization of the components of the putative mammalian sister chromatid cohesion complex
19. Mechanisms of DNA replication
20. A role for the replication proteins PCNA, RF-C, polymerase epsilon and cdc45 in transcriptional silencing in Saccharomyces cerevisiae
21. Protein interaction maps for complete genomes based on gene fusion events
22. Positive and negative regulation of telomerase access to the telomere
23. Identification of replication factor C from Saccharomycex cerevisiae: A component of the leading-strand DNA replication complex
24. Dna2 mutants reveal interactions with Dna polymerase alpha and Ctf4, a Pol alpha accessory factor, and show that full Dna2 helicase activity is not essential for growth
25. Insertional mutations in the yeast HOP1 gene: Evidence for multimeric assembly in meiosis
26. Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase
27. A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk
28. Overproduction and affinity purification of Saccharomyces replication factor C
29. Genetic transformation of yeast
30. Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast
31. A novel Rad24 checkpoint protein complex closely related to replication factor C
32. Chromosome condensation and sister chromatid pairing in budding yeast
33. A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
34. sepB: An Aspergillus nidulans gene involved in chromosome segregation and the initiation of cytokinesis
35. Pds5p is an essential chromosomal protein required for both sister chromatid cohesion and condensation in Saccharomyces cerevisiae
36. Transient sister chromatid separation and elastic deformation of chromosomes during mitosis in budding yeast
37. The RHC21 gene of budding yeast, a homologue of the fission yeast rad21 + gene, is essential for chromosome segregation
38. Sliding clamps: A (tail)ored fit
39. A heterodimeric coiled-coli protein required for mitotic chromosome condensation in vitro
40. Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xehnopus homolog of the Drosophila Barren protein
41. CDC44: A putative nucleotide-binding protein required for cell cycle progression that has homology, to subunits of replication factor C
42. Eukaryotic DNA polymerases, a growing family
43. Multiple sequence alignment with Clustal X
44. SMC proteins constitute two subunits of the mammalian recombination complex RC-1
45. Analysis of the mammalian recombination protein complex RC-1
46. PCNA: Structure, functions and interactions
47. Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast
48. Epitope tagging of yeast genes using a PCR-based strategy: More tags and improved practical routines
49. Sister chromatid cohesion: The beginning of a long and beautiful relationship
50. CTF4 (CHL15) mutants exhibit defective DNA metabolism in the yeast Saccharomyces cerevisiae
51. Identification and genetic mapping of CHL genes controlling mitotic chromosome transmission in yeast
52. CHL12, a gene essential for the fidelity of chromosome transmission in the yeast Saccharomyces cerevisiae
53. Establishing genetic interactions by a synthetic dosage lethality phenotype
54. Isolation of ORC6, a component of the yeast origin recognition complex by a one-hybrid system
55. Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen
56. Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
57. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion
58. Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes
59. An alternative pathway for yeast telomere maintenance rescues est1 - Senescence
60. Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length
61. G2/M checkpoint genes of Saccharomyces cerevisiae: Further evidence for roles in DNA replication and/or repair
62. Detecting protein function and protein-protein interactions from genome sequences
63. CDC7 kinase complex as a molecular switch for DNA replication
64. Proliferating cellnuclear antigen (po130) mutations suppress cdc44 mutations and identify potential regions of interaction between the two encoded proteins
65. The centromeric sister chromatid cohesion site directs Mcdlp binding to adjacent sequences
66. The RAD52 recombinational repair pathway is essential in po130 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis
67. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
68. Evidence that POB1, a Saccharomyces cerevisiae protein that binds to DNA polymerase alpha, acts in DNA metabolism in vivo
69. Regulation of the APC and the exit from mitosis
70. Clamping down on clamps and clamp loaders - The eukaryotic replication factor C
71. Separating sister chromatids
72. Splitting the chromosome: Cutting the ties that bind sister chromatids
73. Human p53 CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae
74. The RFC2 gene, encoding the third-largest subunit of the replication factor-C complex, is required for an S-phase checkpoint in Saccharomyces cerevisiae
75. The telomerase reverse transcriptase: Components and regulation
76. The ties that bind: Localization of the sister chromatid cohesin complex on yeast chromosomes
77. Pds5 cooperates with cohesin in maintaining sister chromatid cohesion
78. Functionally interacting telomerase RNAs in the yeast telomerase
79. The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRAD9
80. Nipped-B, a Drosophila homologue of chromosomal adherins, participates in activation by remote enhancers in the cut and Ultrabithorax genes
81. Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics
82. The rad9 gene of Coprinus cinereus encodes a proline-rich protein required for meiotic chromosome condensation and synapsis
83. Generation of telomere-length heterogeneity in Saccharomyces cerevisiae
84. Functional and physical interaction between RAD24 and RFC5 in the yeast checkpoint pathways
85. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
86. Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery
87. Ctf7p is essential for sister chromatid cohesion and links mitoticchromosome structure to the DNA replication machinery
88. Holding your own: Establishing sister chromatid cohesion
89. A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors
90. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization
91. Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae
92. GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion
93. Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway
94. Characterization of vertebrate cohesin complexes and their regulation in prophase
95. Cell cycle. Replication meets cohesion
96. Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase
97. Identification of cohesin association sites at centromeres and along chromosome arms
98. Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion
99. Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation
100. Characterization of fission yeast cohesin: Essential anaphase proteolysis of Rad21 phosphorylated in the S phase
101. Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication
102. Cohesion between sister chromatids must be established during DNA replication
103. Deletion analysis of the large subunit p140 in human replication factor C reveals regions required for complex formation and replication activities
104. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
105. Structure-based predictions of Rad1, Rad9, Hus1, and Rad17 participation in sliding clamp and clamp-loading complexes
106. Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro
107. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase
108. Pol kappa: A DNA polymerase required for sister chromatid cohesion
109. Drad21, a Drosophila rad21 homologue expressed in S-phase cells
110. Cohesin Rec8 is required for reductional chromosome segregation at meiosis
111. DNA damage and checkpoint pathways: Molecular anatomy and interactions with repair
112. The Saccharomyces DNA polymerase alpha catalytic subunit interacts with CDC68/SPT16, andwith POB3, a protein similar to an HMG-1-like protein
113. Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha
114. Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader
115. Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function
116. Cell cycle mechanisms of sister chromatid separation; roles of Cut1/separin and Cut2/securin
117. Trading places on DNA - A three-point switch underlies primer handoff from primase to the replicative DNA polymerase
118. Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme
119. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools