Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice

Free Radical Biology and Medicine

Volumn 43, Issue 9, 2007, Pages 1335-1347

  Limón Pacheco, Jorge H ^a   Hernández, Norma A ^b   Fanjul Moles, María L ^a   Gonsebatt, María E ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

Author keywords

Glutathione; Mitogen activated protein kinases; Organ specific regulation; Redox environment

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 2; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; THIOREDOXIN; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GAMMAGCSR GENE; GENE INDUCTION; GLUTATHIONE METABOLISM; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; TX 1 GENE;

ACETYLCYSTEINE; ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; ANTIOXIDANTS; BRAIN; BUTADIENES; BUTHIONINE SULFOXIMINE; GLUTATHIONE; IMIDAZOLES; KIDNEY; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRILES; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-JUN; PYRIDINES; REACTIVE OXYGEN SPECIES; SULFHYDRYL COMPOUNDS;

MUS;

EID: 34548762437     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.06.028     Document Type: Article

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