메뉴 건너뛰기




Volumn 67, Issue 5, 1996, Pages 2164-2171

Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons

Author keywords

Aging; Buthionine sulfoximine; Cellular metabolism; Glutathione; Neuronal cell damage; Oxidative stress

Indexed keywords

BUTHIONINE SULFOXIMINE; DOPAMINE; GLUTATHIONE; LIPOFUSCIN;

EID: 0029845402     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67052164.x     Document Type: Article
Times cited : (71)

References (45)
  • 1
    • 0003240656 scopus 로고
    • Catecholaminergic cell atrophy in a transgenic mouse aberrantly overexpressing MAO-B in neurons
    • Andersen J. K., Frim D. M., Isacson O., and Breakefield X. O. (1994) Catecholaminergic cell atrophy in a transgenic mouse aberrantly overexpressing MAO-B in neurons. Neurodegeneration 3, 97-109.
    • (1994) Neurodegeneration , vol.3 , pp. 97-109
    • Andersen, J.K.1    Frim, D.M.2    Isacson, O.3    Breakefield, X.O.4
  • 2
    • 0021592857 scopus 로고
    • The possible relationship of glutathione, melanin, and 1-methyl-4-pnenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease
    • Bannon M. J., Goedert M., and Wolff O. H. (1984) The possible relationship of glutathione, melanin, and 1-methyl-4-pnenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease. Biochem. Pharmacol. 33, 2697-2698.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 2697-2698
    • Bannon, M.J.1    Goedert, M.2    Wolff, O.H.3
  • 3
    • 0026584524 scopus 로고
    • Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
    • Beal F. (1992) Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann. Neurol. 31, 119-130.
    • (1992) Ann. Neurol. , vol.31 , pp. 119-130
    • Beal, F.1
  • 4
    • 0026692807 scopus 로고
    • Role of iron and iron chelation in dopaminergic-induced neurodegeneration: Implications for Parkinson's disease
    • Ben-Shachar D., Eschel G., Riederer P., and Youdim M. B. H. (1992) Role of iron and iron chelation in dopaminergic-induced neurodegeneration: implications for Parkinson's disease. Ann. Neurol. 32 (Suppl.), S105-S110.
    • (1992) Ann. Neurol. , vol.32 , Issue.SUPPL.
    • Ben-Shachar, D.1    Eschel, G.2    Riederer, P.3    Youdim, M.B.H.4
  • 5
    • 10244254316 scopus 로고
    • The significance of lipofuscin in the aging process, especially in neurons
    • (Terry R. D., Bolis C. L., and Toffano G., eds). Raven Press, New York
    • Beregi E. (1982) The significance of lipofuscin in the aging process, especially in neurons, in Neural Aging and Its Implications in Human Neurological Pathology (Terry R. D., Bolis C. L., and Toffano G., eds). pp. 15-21. Raven Press, New York.
    • (1982) Neural Aging and Its Implications in Human Neurological Pathology , pp. 15-21
    • Beregi, E.1
  • 6
    • 0027406823 scopus 로고
    • Age dependence of striatal neuronal death caused by mitochondrial dysfunction
    • Bossi S. R., Simpson J. R., and Isacson I. (1993) Age dependence of striatal neuronal death caused by mitochondrial dysfunction. Neuroreport 4, 73-76.
    • (1993) Neuroreport , vol.4 , pp. 73-76
    • Bossi, S.R.1    Simpson, J.R.2    Isacson, I.3
  • 7
    • 0024502303 scopus 로고
    • The effect of aging on glutathione and cysteine levels in different regions of the mouse brain
    • Chen T. S., Richie J. P., and Lang C. A. (1989) The effect of aging on glutathione and cysteine levels in different regions of the mouse brain. Proc. Soc. Exp. Biol. Med. 190, 399-402.
    • (1989) Proc. Soc. Exp. Biol. Med. , vol.190 , pp. 399-402
    • Chen, T.S.1    Richie, J.P.2    Lang, C.A.3
  • 8
    • 0038759584 scopus 로고
    • Fluorescence methods for the histochemical demonstration of monoamines. 3. Sodium borohydride reduction of the fluorescent compounds as a specificity test
    • Corrodi H., Hillard N., and Jonsson G. (1964) Fluorescence methods for the histochemical demonstration of monoamines. 3. Sodium borohydride reduction of the fluorescent compounds as a specificity test. J. Histochem. Cytochem. 12, 582-586.
    • (1964) J. Histochem. Cytochem. , vol.12 , pp. 582-586
    • Corrodi, H.1    Hillard, N.2    Jonsson, G.3
  • 9
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative diseases
    • Coyle J. T. and Puttfarcken P. (1993) Oxidative stress, glutamate, and neurodegenerative diseases. Science 262, 689-694.
    • (1993) Science , vol.262 , pp. 689-694
    • Coyle, J.T.1    Puttfarcken, P.2
  • 10
    • 0026514680 scopus 로고
    • Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains
    • De Haan J. B., Newman J. D., and Kola I. (1992) Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains. Brain Res. Mol. Brain Res. 13, 179-187.
    • (1992) Brain Res. Mol. Brain Res. , vol.13 , pp. 179-187
    • De Haan, J.B.1    Newman, J.D.2    Kola, I.3
  • 12
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S. and Cohen G. (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol. 32, 804-812.
    • (1992) Ann. Neurol. , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 14
    • 0018128688 scopus 로고
    • Aqueous aldehyde (FAGLU) methods for the fluorescence histochemical localization of catecholamines and for ultrastructural studies of central nervous tissue
    • Furness J. B., Heath J. W., and Costa M. (1978) Aqueous aldehyde (FAGLU) methods for the fluorescence histochemical localization of catecholamines and for ultrastructural studies of central nervous tissue. Histochemistry 57, 285-295.
    • (1978) Histochemistry , vol.57 , pp. 285-295
    • Furness, J.B.1    Heath, J.W.2    Costa, M.3
  • 15
    • 0015881679 scopus 로고
    • The histochemical fluorescence method for the demonstration of catecholamines
    • Fuxe K. and Jonsson G. (1973) The histochemical fluorescence method for the demonstration of catecholamines. J. Histochem. Cytochem. 21, 293-311.
    • (1973) J. Histochem. Cytochem. , vol.21 , pp. 293-311
    • Fuxe, K.1    Jonsson, G.2
  • 16
    • 0028000825 scopus 로고
    • Altered brain metabolism of iron as a cause for neurodegenerative disease?
    • Gerlach M., Ben-Shachar D., Riederer P., and Youdim M. B. H. (1994) Altered brain metabolism of iron as a cause for neurodegenerative disease? J. Neurochem. 63, 793-807.
    • (1994) J. Neurochem. , vol.63 , pp. 793-807
    • Gerlach, M.1    Ben-Shachar, D.2    Riederer, P.3    Youdim, M.B.H.4
  • 17
    • 0018095085 scopus 로고
    • Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
    • Graham D. G. (1978) Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14, 633-643.
    • (1978) Mol. Pharmacol. , vol.14 , pp. 633-643
    • Graham, D.G.1
  • 18
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith O. W. and Meister A. (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J. Biol. Chem. 254, 7558-7560.
    • (1979) J. Biol. Chem. , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 19
    • 0022501692 scopus 로고
    • Aged mice are more sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment than young adults
    • Gupta M., Gupta B. K., Thomas R., Bruemmer V., Sladek J. R. Jr., and Felten D.-L. (1986) Aged mice are more sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment than young adults. Neurosci. Lett. 70, 326-331.
    • (1986) Neurosci. Lett. , vol.70 , pp. 326-331
    • Gupta, M.1    Gupta, B.K.2    Thomas, R.3    Bruemmer, V.4    Sladek Jr., J.R.5    Felten, D.-L.6
  • 21
    • 0024381035 scopus 로고
    • Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse
    • Heikkila R. E., Sieber B.-A., Manzino L., and Sonsalla P. K. (1989) Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. Mol. Chem. Neuropathol. 10, 171-181.
    • (1989) Mol. Chem. Neuropathol. , vol.10 , pp. 171-181
    • Heikkila, R.E.1    Sieber, B.-A.2    Manzino, L.3    Sonsalla, P.K.4
  • 22
    • 0026637866 scopus 로고
    • Why are catecholaminergic neurons more vulnerable than other cells in Parkinson's disease?
    • Hirsch E. C. (1992) Why are catecholaminergic neurons more vulnerable than other cells in Parkinson's disease? Ann. Neurol. 32 (Suppl.), S88-S93.
    • (1992) Ann. Neurol. , vol.32 , Issue.SUPPL.
    • Hirsch, E.C.1
  • 23
    • 0023251887 scopus 로고
    • Depletion of tumor versus normal tissue glutathione by buthionine sulfoximine
    • Lee F. Y. F., Allalunis-Turner J., and Siemann D. W. (1987) Depletion of tumor versus normal tissue glutathione by buthionine sulfoximine. Br. J. Cancer 56, 33-38.
    • (1987) Br. J. Cancer , vol.56 , pp. 33-38
    • Lee, F.Y.F.1    Allalunis-Turner, J.2    Siemann, D.W.3
  • 24
    • 0023719874 scopus 로고
    • Glutathione contents in humans and rodent cells in various phases of the cell cycle
    • Lee F. Y. F., Siemann D., Allalunis-Turner J., and Keng P. (1988) Glutathione contents in humans and rodent cells in various phases of the cell cycle. Cancer Res. 48, 3661-3665.
    • (1988) Cancer Res. , vol.48 , pp. 3661-3665
    • Lee, F.Y.F.1    Siemann, D.2    Allalunis-Turner, J.3    Keng, P.4
  • 25
    • 0018366531 scopus 로고
    • Aging and unusual catecholamine-containing structures in the mouse brain
    • Masuoka D. T., Jonsson G., and Finch C. E. (1979) Aging and unusual catecholamine-containing structures in the mouse brain. Brain Res. 169, 335-341.
    • (1979) Brain Res. , vol.169 , pp. 335-341
    • Masuoka, D.T.1    Jonsson, G.2    Finch, C.E.3
  • 26
    • 0021341684 scopus 로고
    • Age-correlated changes in dopaminergic nigrostriatal perikarya of the C57BL/6NNi mouse
    • McNeill T. H., Koek L. L., and Haycock J. W. (1984) Age-correlated changes in dopaminergic nigrostriatal perikarya of the C57BL/6NNi mouse. Mech. Ageing Dev. 24, 293-307.
    • (1984) Mech. Ageing Dev. , vol.24 , pp. 293-307
    • McNeill, T.H.1    Koek, L.L.2    Haycock, J.W.3
  • 28
    • 0029012874 scopus 로고
    • Oxidative damage in aged mouse brain correlates with decreases in protective enzymes
    • Mo J. Q., Hom D. G., and Andersen J. K. (1995) Oxidative damage in aged mouse brain correlates with decreases in protective enzymes. Mech. Aging Dev. 81, 73-82.
    • (1995) Mech. Aging Dev. , vol.81 , pp. 73-82
    • Mo, J.Q.1    Hom, D.G.2    Andersen, J.K.3
  • 29
    • 0023095333 scopus 로고
    • Dopamine and serotonin systems in human and rodent brain: Effects of age and degenerative disease
    • Morgan D. G., May P. C., and Finch C. E. (1987) Dopamine and serotonin systems in human and rodent brain: effects of age and degenerative disease. J. Am. Geriatr. Soc. 35, 334-345.
    • (1987) J. Am. Geriatr. Soc. , vol.35 , pp. 334-345
    • Morgan, D.G.1    May, P.C.2    Finch, C.E.3
  • 30
    • 0015170764 scopus 로고
    • Properties of neuronal lipofuscin pigment in mice
    • Nandy J. (1971) Properties of neuronal lipofuscin pigment in mice. Acta Neuropathol. (Berl.) 19, 25-32.
    • (1971) Acta Neuropathol. (Berl.) , vol.19 , pp. 25-32
    • Nandy, J.1
  • 31
    • 0022553605 scopus 로고
    • Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
    • Perry T. L. and Yong V. W. (1986) Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci. Lett. 67, 269-274.
    • (1986) Neurosci. Lett. , vol.67 , pp. 269-274
    • Perry, T.L.1    Yong, V.W.2
  • 32
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigral glutathione deficiency?
    • Perry T. L., Godin D. V., and Hansen S. (1982) Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci. Lett. 33, 305-310.
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.V.2    Hansen, S.3
  • 33
    • 0024426696 scopus 로고
    • Intracerebroventricular administration of L-buthionine sulfoximine: A method for depleting brain glutathione
    • Pileblad E. and Magnusson T. (1989) Intracerebroventricular administration of L-buthionine sulfoximine: a method for depleting brain glutathione. J. Neurochem. 53, 1878-1882.
    • (1989) J. Neurochem. , vol.53 , pp. 1878-1882
    • Pileblad, E.1    Magnusson, T.2
  • 34
    • 0025604179 scopus 로고
    • Effective depletion of glutathione in rat striatum and substantia nigra by L-buthionine sulfoximine in combination with 2-cyclohexen-1-one
    • Pileblad E. and Magnusson T. (1990) Effective depletion of glutathione in rat striatum and substantia nigra by L-buthionine sulfoximine in combination with 2-cyclohexen-1-one. Life Sci. 47, 2333-2342.
    • (1990) Life Sci. , vol.47 , pp. 2333-2342
    • Pileblad, E.1    Magnusson, T.2
  • 35
    • 0021240616 scopus 로고
    • Glutathione depletion and susceptibility
    • Reed D. J. and Fariss M. W. (1984) Glutathione depletion and susceptibility. Pharmacol. Rev. 36 (Suppl.), 25S-33S.
    • (1984) Pharmacol. Rev. , vol.36 , Issue.SUPPL.
    • Reed, D.J.1    Fariss, M.W.2
  • 36
    • 0023070786 scopus 로고
    • Older dopaminergic neurons do not recover from the effects of MPTP
    • Ricaurte G. A., DeLanney L. E., Irwin I., and Langston J. W. (1987a) Older dopaminergic neurons do not recover from the effects of MPTP. Neuropharmacology 26, 97-99.
    • (1987) Neuropharmacology , vol.26 , pp. 97-99
    • Ricaurte, G.A.1    Delanney, L.E.2    Irwin, I.3    Langston, J.W.4
  • 37
    • 0023141542 scopus 로고
    • Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra
    • Ricaurte G. A., Irwin I., Forno L. S., DeLanney L. E., Langston E., and Langston J. W. (1987b) Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra. Brain Res. 403, 43-51.
    • (1987) Brain Res. , vol.403 , pp. 43-51
    • Ricaurte, G.A.1    Irwin, I.2    Forno, L.S.3    DeLanney, L.E.4    Langston, E.5    Langston, J.W.6
  • 39
    • 0023937735 scopus 로고
    • Depletion of brain glutathione in preweanling mice by L-buthionine sulfoximine
    • Slivka A., Spina M. B., Calvin H. I., and Cohen G. (1988) Depletion of brain glutathione in preweanling mice by L-buthionine sulfoximine. J. Neurochem. 50, 1391-1393.
    • (1988) J. Neurochem. , vol.50 , pp. 1391-1393
    • Slivka, A.1    Spina, M.B.2    Calvin, H.I.3    Cohen, G.4
  • 41
    • 0025963530 scopus 로고
    • Selective increase of iron in substantia nigra zona compacta of parkinsonian brains
    • Sofic E., Paulus W., Jellinger K., Riederer P., and Youdim M. B. H. (1991) Selective increase of iron in substantia nigra zona compacta of parkinsonian brains. J. Neurochem. 56, 978-982.
    • (1991) J. Neurochem. , vol.56 , pp. 978-982
    • Sofic, E.1    Paulus, W.2    Jellinger, K.3    Riederer, P.4    Youdim, M.B.H.5
  • 42
    • 0029009907 scopus 로고
    • Buthionine sulfoximine-induced glutathione depletion. Its effect on antioxidants, lipid peroxidation and calcium homeostasis in the lung
    • Thanislass J., Raveendran M., and Devaraj H. (1995) Buthionine sulfoximine-induced glutathione depletion. Its effect on antioxidants, lipid peroxidation and calcium homeostasis in the lung. Biochem. Pharmacol. 50, 229-234.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 229-234
    • Thanislass, J.1    Raveendran, M.2    Devaraj, H.3
  • 43
    • 0022650447 scopus 로고
    • Depletion of glutathione in brainstem of mice by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant treatment
    • Yong V. W., Perry T. L., and Krisman A. A. (1986) Depletion of glutathione in brainstem of mice by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant treatment. Neurosci. Lett. 63, 56-60.
    • (1986) Neurosci. Lett. , vol.63 , pp. 56-60
    • Yong, V.W.1    Perry, T.L.2    Krisman, A.A.3
  • 44
    • 0027329926 scopus 로고
    • The role of iron in senescence of dopaminergic neurons in Parkinson's disease
    • Youdim M. B. H. and Riederer P. J. (1993) The role of iron in senescence of dopaminergic neurons in Parkinson's disease. J. Neural Transm. 40, 57-67.
    • (1993) J. Neural Transm. , vol.40 , pp. 57-67
    • Youdim, M.B.H.1    Riederer, P.J.2
  • 45
    • 0021997646 scopus 로고
    • Regional lipid peroxidation in rat brain in vitro: Possible role of endogenous iron
    • Zaleska M. M., Nagy K., and Floyd R. A. (1989) Regional lipid peroxidation in rat brain in vitro: possible role of endogenous iron. Neurochem. Res. 10, 397-410.
    • (1989) Neurochem. Res. , vol.10 , pp. 397-410
    • Zaleska, M.M.1    Nagy, K.2    Floyd, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.