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Volumn 17, Issue 8, 1997, Pages 4792-4800

The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N- terminal protein kinases and p38 kinase by alkylating agents

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; GLUTATHIONE; MESYLIC ACID METHYL ESTER; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 0030789179     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.8.4792     Document Type: Article
Times cited : (226)

References (87)
  • 1
    • 0028881770 scopus 로고
    • UV irradiation and heat shock mediate JNK activation via alternate pathways
    • Adler, V., A. Schaffer, J. Kim, L. Dolan, and Z. Ronai. 1995. UV irradiation and heat shock mediate JNK activation via alternate pathways. J. Biol. Chem. 270:26071-26077.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26071-26077
    • Adler, V.1    Schaffer, A.2    Kim, J.3    Dolan, L.4    Ronai, Z.5
  • 2
    • 0001920562 scopus 로고
    • The role and regulation of the Jun proteins in response to phorbol ester and UV light
    • P. Baeuerle (ed.) Birkhäuser Verlag. Boston, Mass.
    • Angel, P. 1995. The role and regulation of the Jun proteins in response to phorbol ester and UV light., p. 62-92. In P. Baeuerle (ed.). Inducible gene expression and cytoplasmic/nuclear signal transduction. Birkhäuser Verlag. Boston, Mass.
    • (1995) Inducible Gene Expression and Cytoplasmic/nuclear Signal Transduction , pp. 62-92
    • Angel, P.1
  • 3
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P., and M. Karin. 1991. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochem. Biophys. Acta 1072:129-157.
    • (1991) Biochem. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 4
    • 0024276523 scopus 로고
    • The c-jun protooncogene is positively autoregulated by its product, Jun/AP-1
    • Angel, P., K. Hatturi, T. Smeal, and M. Karin. 1988. The c-jun protooncogene is positively autoregulated by its product, Jun/AP-1. Cell 55:875-885.
    • (1988) Cell , vol.55 , pp. 875-885
    • Angel, P.1    Hatturi, K.2    Smeal, T.3    Karin, M.4
  • 5
    • 0024394697 scopus 로고
    • The antioxidant action of N-acety1 cysteine: Its reaction with hydrogen peroxide, hydroxyl radical, Superoxide and hypochlorous acid
    • Aruoma, O. I., B. Halliwell, B. M. Hoey, and J. Butler. 1989. The antioxidant action of N-acety1 cysteine: its reaction with hydrogen peroxide, hydroxyl radical, Superoxide and hypochlorous acid. Free Radical Biol. Med. 6:593-597.
    • (1989) Free Radical Biol. Med. , vol.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 6
    • 0028875683 scopus 로고
    • Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
    • Bagrodia, S., B. Dérijard. R. J. Davis, and R. A. Cerione. 1995. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 270:27995-27998.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27995-27998
    • Bagrodia, S.1    Dérijard, B.2    Davis, R.J.3    Cerione, R.A.4
  • 7
    • 0019156329 scopus 로고
    • A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography
    • Beranek, D. T., C. C. Weis, and D. H. Swenson. 1980. A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography. Carcinogenesis 1:595-606.
    • (1980) Carcinogenesis , vol.1 , pp. 595-606
    • Beranek, D.T.1    Weis, C.C.2    Swenson, D.H.3
  • 8
    • 0028008680 scopus 로고
    • Intracellular glutathione levels regulate Fos/Jun induction and activation of glutathione S-transferase gene expression
    • Bergelson, S., R. Pinkus, and V. Daniel. 1994. Intracellular glutathione levels regulate Fos/Jun induction and activation of glutathione S-transferase gene expression. Cancer Res. 54:36-40.
    • (1994) Cancer Res. , vol.54 , pp. 36-40
    • Bergelson, S.1    Pinkus, R.2    Daniel, V.3
  • 9
    • 0342350445 scopus 로고
    • Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin
    • Betzholtz, C., A. Johnsson, C.-H. Heldin, and B. Westermark. 1986. Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin. Proc. Natl. Acad. Sci. USA 83:6440-6444.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6440-6444
    • Betzholtz, C.1    Johnsson, A.2    Heldin, C.-H.3    Westermark, B.4
  • 10
    • 0026655577 scopus 로고
    • Cellular glutathione (GSH) and glutathione-S-transferases (GST) activity in human ovarian tumor biopsies following exposure to alkylating agents
    • Britten, R. A., J. A. Green, and H. M. Warenius. 1992. Cellular glutathione (GSH) and glutathione-S-transferases (GST) activity in human ovarian tumor biopsies following exposure to alkylating agents. Int. J. Radiat. Oncol. Biol. Phys. 24:527-531.
    • (1992) Int. J. Radiat. Oncol. Biol. Phys. , vol.24 , pp. 527-531
    • Britten, R.A.1    Green, J.A.2    Warenius, H.M.3
  • 11
    • 0019739717 scopus 로고
    • Methods for enucleation and reconstruction of interferon-producing cells
    • Burke, D. C. 1981. Methods for enucleation and reconstruction of interferon-producing cells. Methods Enzymol. 79:552-557.
    • (1981) Methods Enzymol. , vol.79 , pp. 552-557
    • Burke, D.C.1
  • 12
    • 0028052255 scopus 로고
    • Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun
    • Cano, E., C. A. Hazzalin, and L. C. Mahadevan. 1994. Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun. Mol. Cell. Biol. 14:7352-7362.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7352-7362
    • Cano, E.1    Hazzalin, C.A.2    Mahadevan, L.C.3
  • 13
    • 0028793798 scopus 로고
    • Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation
    • Cavigelli, M., F. Dolfi, F.-X. Claret, and M. Karin. 1995. Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J. 14:5957-5964.
    • (1995) EMBO J. , vol.14 , pp. 5957-5964
    • Cavigelli, M.1    Dolfi, F.2    Claret, F.-X.3    Karin, M.4
  • 14
    • 0029858594 scopus 로고    scopus 로고
    • The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase
    • Cavigelli, M., W. Li, A. Lin, B. Su, K. Yoshioka, and M. Karin. 1996. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J. 15:6296-6279.
    • (1996) EMBO J. , vol.15 , pp. 6296-16279
    • Cavigelli, M.1    Li, W.2    Lin, A.3    Su, B.4    Yoshioka, K.5    Karin, M.6
  • 15
    • 0018368359 scopus 로고
    • The role of glutathione and glutathione-S-transferases in the metabolism of chemical carcinogens and other electrophilic agents
    • Chasseaud, L. F. 1979. The role of glutathione and glutathione-S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Adv. Cancer Res. 29:175-274.
    • (1979) Adv. Cancer Res. , vol.29 , pp. 175-274
    • Chasseaud, L.F.1
  • 16
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac-1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso, O. A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J. S. Gutkind. 1995. The small GTP-binding proteins Rac-1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81:1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.-C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 17
    • 0030047481 scopus 로고
    • Signaling from G-protein coupled receptors to c-Jun kinase involves βγ suhunits of heterotrimeric G proteins acting on a Ras and Racl-dependent pathway
    • Coso, O. A., H. Teramoto, W. F. Simonds, and J. S. Gutkind. 1995. Signaling from G-protein coupled receptors to c-Jun kinase involves βγ suhunits of heterotrimeric G proteins acting on a Ras and Racl-dependent pathway. J. Biol. Chem. 271:3963-3966.
    • (1995) J. Biol. Chem. , vol.271 , pp. 3963-3966
    • Coso, O.A.1    Teramoto, H.2    Simonds, W.F.3    Gutkind, J.S.4
  • 19
    • 0028073283 scopus 로고
    • MAPKs: New JNK expands the group
    • Davis, R. J. 1994. MAPKs: new JNK expands the group. Trends Biochem. Sci. 19:470-473.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 470-473
    • Davis, R.J.1
  • 20
    • 0027173483 scopus 로고
    • JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers
    • Deng, T.. and M. Karin. 1993. JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. Genes Dev. 7:479-490.
    • (1993) Genes Dev. , vol.7 , pp. 479-490
    • Deng, T.1    Karin, M.2
  • 21
    • 0028144846 scopus 로고
    • Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK
    • Deng, T., and M. Karin. 1994. c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK. Nature 371: 171-175.
    • (1994) Nature , vol.371 , pp. 171-175
    • Deng, T.1    Karin, M.2
  • 22
    • 0028329953 scopus 로고
    • JNK1 : A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Dérijard, B., M. Hibi, I.-H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1 : a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Dérijard, B.1    Hibi, M.2    Wu, I.-H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 23
    • 0028935974 scopus 로고
    • Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
    • Dérijard, B., J. Raingeaud, T. Barrett, I.-H. Wu, J. Han, R. J. Ulevitch, and R. J. Davis. 1995. Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682-685.
    • (1995) Science , vol.267 , pp. 682-685
    • Dérijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.-H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 24
    • 0026341905 scopus 로고
    • Rapid and preferential activation of the c-jun gene during the mammalian UV response
    • Devary, Y., R. A. Gottlieb, L. F. Lau, and M. Karin. 1991. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol. Cell. Biol. 11:2804-2811.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 2804-2811
    • Devary, Y.1    Gottlieb, R.A.2    Lau, L.F.3    Karin, M.4
  • 25
    • 0027049804 scopus 로고
    • The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases
    • Devary, Y., R. A. Gottlieb, T. Smeal, and M. Karin. 1992. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 71:1081-1091.
    • (1992) Cell , vol.71 , pp. 1081-1091
    • Devary, Y.1    Gottlieb, R.A.2    Smeal, T.3    Karin, M.4
  • 26
    • 0027363407 scopus 로고
    • N κB activation by ultraviolet light not dependent on a nuclear signal
    • Devary, Y., C. Rosette, J. A. DiDonato, and M. Karin. 1993. N κB activation by ultraviolet light not dependent on a nuclear signal. Science 261:1442-1445.
    • (1993) Science , vol.261 , pp. 1442-1445
    • Devary, Y.1    Rosette, C.2    Didonato, J.A.3    Karin, M.4
  • 27
    • 0027994002 scopus 로고
    • An osmosensing signal transduction pathway in mammalian cells
    • Galcheva-Gargova, Z., B. Dérijard, I.-H. Wu, and R. J. Davis. 1994. An osmosensing signal transduction pathway in mammalian cells. Science 265: 806-808.
    • (1994) Science , vol.265 , pp. 806-808
    • Galcheva-Gargova, Z.1    Dérijard, B.2    Wu, I.-H.3    Davis, R.J.4
  • 28
    • 0026695645 scopus 로고
    • TCF by MAP kinase stimulates ternary complex formation at C-fos promoter
    • TCF by MAP kinase stimulates ternary complex formation at C-fos promoter. Nature 358:414-116.
    • (1992) Nature , vol.358 , pp. 414-1116
    • Gille, H.1    Sharrocks, A.D.2    Shaw, P.E.3
  • 29
    • 0029379778 scopus 로고
    • Activation of ternary complex factor Elk-1 by stress-activated protein kinases
    • Gille, H., T. Strahl, and P. E. Shaw. 1995. Activation of ternary complex factor Elk-1 by stress-activated protein kinases. Curr. Biol. 5:1191-1200.
    • (1995) Curr. Biol. , vol.5 , pp. 1191-1200
    • Gille, H.1    Strahl, T.2    Shaw, P.E.3
  • 30
    • 0028931406 scopus 로고
    • ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation
    • Gille, H., M. Kortenjann, O. Thomae, C. Moomaw, C. Slaughter, M. H. Cobb, and P. E. Shaw. 1995. ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J. 14:951-962.
    • (1995) EMBO J. , vol.14 , pp. 951-962
    • Gille, H.1    Kortenjann, M.2    Thomae, O.3    Moomaw, C.4    Slaughter, C.5    Cobb, M.H.6    Shaw, P.E.7
  • 31
    • 0028905076 scopus 로고
    • Transcription factor ATF-2 regulation by the JNK signal transduction pathway
    • Gupta, S., D. Campbell, B. Dérijard, and R. J. Davis. 1995. Transcription factor ATF-2 regulation by the JNK signal transduction pathway. Science 267:389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Dérijard, B.3    Davis, R.J.4
  • 33
    • 0027423418 scopus 로고
    • Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2135-2148.
    • (1993) Genes Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 34
    • 0026230108 scopus 로고
    • Response to adversity: Molecular control of gene activation following genotoxic stress
    • Holbrook, N. J., and A. J. Fornace, Jr. 1991. Response to adversity: molecular control of gene activation following genotoxic stress. New Biol. 3:825-833.
    • (1991) New Biol. , vol.3 , pp. 825-833
    • Holbrook, N.J.1    Fornace Jr., A.J.2
  • 35
    • 0024242552 scopus 로고
    • Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin
    • Huang, S. S., and J. S. Huang, 1988. Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. J. Biol. Chem. 263:12208-12618.
    • (1988) J. Biol. Chem. , vol.263 , pp. 12208-12618
    • Huang, S.S.1    Huang, J.S.2
  • 36
    • 0028587054 scopus 로고
    • Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator
    • Jalink, K., P. L. Hordijk, and W. H. Moolenaar. 1994 Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator. Biochim. Biophys. Acta 1198:185-196.
    • (1994) Biochim. Biophys. Acta , vol.1198 , pp. 185-196
    • Jalink, K.1    Hordijk, P.L.2    Moolenaar, W.H.3
  • 37
    • 0027219303 scopus 로고
    • A null mutation at the C-Jun locus causes embryonic lethality and retarded cell growth in culture
    • Johnson, R. S., B. van Lingen, V. E. Papaioannou, and B. M. Spiegelman. 1993. A null mutation at the C-Jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev. 7:1309-1317.
    • (1993) Genes Dev. , vol.7 , pp. 1309-1317
    • Johnson, R.S.1    Van Lingen, B.2    Papaioannou, V.E.3    Spiegelman, B.M.4
  • 38
    • 0025941670 scopus 로고
    • 6-methylguanine-DNA-methyltransferasc (MGMT) cDNA in Chinese hamster cells: The role of MGMT in protection against genotoxic effects of alkylating agents
    • 6-methylguanine-DNA-methyltransferasc (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against genotoxic effects of alkylating agents. Carcinogenesis 12:1857-1867.
    • (1991) Carcinogenesis , vol.12 , pp. 1857-1867
    • Kaina, B.1    Fritz, G.2    Mitra, S.3    Coquerelle, T.4
  • 40
    • 0029790979 scopus 로고    scopus 로고
    • Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
    • Knebel, A., H. J. Rahmsdorf. A. Ullrich, and P. Herrlich. 1996. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J. 15:5314-5325.
    • (1996) EMBO J. , vol.15 , pp. 5314-5325
    • Knebel, A.1    Rahmsdorf, H.J.2    Ullrich, A.3    Herrlich, P.4
  • 42
  • 43
    • 0024991008 scopus 로고
    • Preventive action of thioethers towards in vitro DNA binding and mutagenesis in e coli K12 by alkylating agents
    • Kroese, E. D., M. J. Zeilmaker, G. R. Mohn, and J. H. N. Meerman. 1990. Preventive action of thioethers towards in vitro DNA binding and mutagenesis in E coli K12 by alkylating agents. Mutat. Res. 245:67-74.
    • (1990) Mutat. Res. , vol.245 , pp. 67-74
    • Kroese, E.D.1    Zeilmaker, M.J.2    Mohn, G.R.3    Meerman, J.H.N.4
  • 45
    • 0026541143 scopus 로고
    • Activation of extracellular signalregulated kinase, ERK2, by p21ras oncoprotein
    • Leevers, S. J., and C. J. Marshall. 1992. Activation of extracellular signalregulated kinase, ERK2, by p21ras oncoprotein. EMBO J. 11:569-574.
    • (1992) EMBO J. , vol.11 , pp. 569-574
    • Leevers, S.J.1    Marshall, C.J.2
  • 47
    • 0029856557 scopus 로고    scopus 로고
    • Three distinct signalling responses by murine fibroblasts to genotoxic stress
    • Liu, Z. G., R. Baskaran, E. Lea-Chou, L. D. Wood, Y. Chen, M. Karin, and J. Y. J. Wang. 1996. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature 384:273-276.
    • (1996) Nature , vol.384 , pp. 273-276
    • Liu, Z.G.1    Baskaran, R.2    Lea-Chou, E.3    Wood, L.D.4    Chen, Y.5    Karin, M.6    Wang, J.Y.J.7
  • 48
    • 0029034251 scopus 로고
    • ATF-2 contains a phosphorylation-dependent transcriptional activation domain
    • Livingstone, C., G. Patel, and N. Jones. 1995. ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14:1785-1797.
    • (1995) EMBO J. , vol.14 , pp. 1785-1797
    • Livingstone, C.1    Patel, G.2    Jones, N.3
  • 49
    • 0028594069 scopus 로고
    • Glu tathione can rescue the inhibitory effects of nickel on DNA ligation and repair synthesis
    • Lynn, S., F. H. Yew, J.-W. Hwang, M.-J. Tseng, and K. Y. Jan. 1994. Glu tathione can rescue the inhibitory effects of nickel on DNA ligation and repair synthesis. Carcinogenesis 15:2811-2816.
    • (1994) Carcinogenesis , vol.15 , pp. 2811-2816
    • Lynn, S.1    Yew, F.H.2    Hwang, J.-W.3    Tseng, M.-J.4    Jan, K.Y.5
  • 50
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall, C. J. 1995. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 51
    • 0020537304 scopus 로고
    • Selective modification of glutathione metabolism
    • Meister, A. 1983. Selective modification of glutathione metabolism. Science 220:472-477.
    • (1983) Science , vol.220 , pp. 472-477
    • Meister, A.1
  • 52
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis and its reversal. Applications in research and therapy
    • Meister, A. 1991. Glutathione deficiency produced by inhibition of its synthesis and its reversal. Applications in research and therapy. Pharmacol. Ther. 51:155-194.
    • (1991) Pharmacol. Ther. , vol.51 , pp. 155-194
    • Meister, A.1
  • 54
    • 0029070887 scopus 로고
    • Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
    • Minden, A., A. Lin, F.-X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81:1147-1157.
    • (1995) Cell , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.-X.3    Abo, A.4    Karin, M.5
  • 55
    • 0027369091 scopus 로고
    • Roles for oxidative stress and poly(ADP-ribosyl)ation in the killing of cultured hepatocytes by methyl methane-sulfonate
    • Mizumoto, K., P. A. Glascott, Jr., and J. L. Farber. 1993. Roles for oxidative stress and poly(ADP-ribosyl)ation in the killing of cultured hepatocytes by methyl methane-sulfonate. Biochem. Pharmacol. 46:1811-1818.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1811-1818
    • Mizumoto, K.1    Glascott Jr., P.A.2    Farber, J.L.3
  • 56
    • 0028903101 scopus 로고
    • Lysophosphatidic acid signalling
    • Moolenaar, W. H. 1995. Lysophosphatidic acid signalling. Curr. Opin. Cell Biol. 7:203-210.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 203-210
    • Moolenaar, W.H.1
  • 57
    • 0029032202 scopus 로고
    • Lysophosphatidic acid, a multifunctional phospholipid messenger
    • Moolenaar, W. H. 1995. Lysophosphatidic acid, a multifunctional phospholipid messenger. J. Biol. Chem. 270:12949-12952.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12949-12952
    • Moolenaar, W.H.1
  • 58
    • 0025959674 scopus 로고
    • Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun
    • Morgan, J. I., and T. Curran. 1991. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu. Rev. Neurosci. 14:421-451.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 421-451
    • Morgan, J.I.1    Curran, T.2
  • 59
    • 0029039180 scopus 로고
    • Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases
    • Moriguchi, T., H. Kawasaki, S. Matsuda, Y. Gotoh, and E. Nishida. 1995. Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases. J. Biol. Chem. 270:12969-12972.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12969-12972
    • Moriguchi, T.1    Kawasaki, H.2    Matsuda, S.3    Gotoh, Y.4    Nishida, E.5
  • 60
    • 0021210117 scopus 로고
    • Relationship between cell killing, chromosomal aberrations, sisterchromatid exchanges and point mutations induced by monofunctional alkylating agents in Chinese hamster cells
    • Natarajan, A. T., J. W. I. M. Simons, E. W. Vogel, and A. A. van Zeeland. 1984. Relationship between cell killing, chromosomal aberrations, sisterchromatid exchanges and point mutations induced by monofunctional alkylating agents in Chinese hamster cells. Mutat. Res. 128:31-40.
    • (1984) Mutat. Res. , vol.128 , pp. 31-40
    • Natarajan, A.T.1    Simons, J.W.I.M.2    Vogel, E.W.3    Van Zeeland, A.A.4
  • 61
    • 0029101360 scopus 로고
    • An essential role for Rho, Rac, Cdc42 GTPases in cell cycle progression through G1
    • Olson, M. F., A. Ashworth, and A. Hall. 1995. An essential role for Rho, Rac, Cdc42 GTPases in cell cycle progression through G1. Science 269:1270-1272.
    • (1995) Science , vol.269 , pp. 1270-1272
    • Olson, M.F.1    Ashworth, A.2    Hall, A.3
  • 62
    • 0021140925 scopus 로고
    • Alkylation of protein by methyl methanesulfonate and 1-methyl-nitrosourea in vitro
    • Paik, W. K., S. Kim, P. N. Magee, and P. D. Lotlikar. 1984. Alkylation of protein by methyl methanesulfonate and 1-methyl-nitrosourea in vitro. Cancer Lett. 23:9-17.
    • (1984) Cancer Lett. , vol.23 , pp. 9-17
    • Paik, W.K.1    Kim, S.2    Magee, P.N.3    Lotlikar, P.D.4
  • 65
    • 0027392874 scopus 로고
    • Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells
    • Pulverer, B. J., K. Hughes, C. C. Franklin, A. S. Kraft, S. J. Leevers, and J. R. Woodgett. 1993. Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells. Oncogene 8:407-415.
    • (1993) Oncogene , vol.8 , pp. 407-415
    • Pulverer, B.J.1    Hughes, K.2    Franklin, C.C.3    Kraft, A.S.4    Leevers, S.J.5    Woodgett, J.R.6
  • 67
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud, J., S. Gupta, J. S. Rogers, M. Dickens, J. Han, R. J. Ulevitch. and R. J. Davis. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270:7420-7426.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 69
    • 0028558986 scopus 로고
    • Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
    • Sanchez, I., R. T. Hughes, B. J. Mayer, K. Yee, J. R. Woodgett, J. Avruch, J. M. Kyriakis, and L. I. Zon. 1994. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372: 794-798.
    • (1994) Nature , vol.372 , pp. 794-798
    • Sanchez, I.1    Hughes, R.T.2    Mayer, B.J.3    Yee, K.4    Woodgett, J.R.5    Avruch, J.6    Kyriakis, J.M.7    Zon, L.I.8
  • 70
    • 0028818599 scopus 로고
    • Fos is an essential component of the mammalian UV response
    • Schreiber, M., B. Baumann. M. Cotten, P. Angel, and E. F. Wagner. 1995. Fos is an essential component of the mammalian UV response. EMBO J. 14:5338-5349.
    • (1995) EMBO J. , vol.14 , pp. 5338-5349
    • Schreiber, M.1    Baumann, B.2    Cotten, M.3    Angel, P.4    Wagner, E.F.5
  • 71
    • 0345625740 scopus 로고
    • A review of the genotoxicity of 1-ethyl-1-nitrosourea
    • Shibuya, T., and K. Morimoto. 1993. A review of the genotoxicity of 1-ethyl-1-nitrosourea. Mutat. Res. 297:3-38.
    • (1993) Mutat. Res. , vol.297 , pp. 3-38
    • Shibuya, T.1    Morimoto, K.2
  • 72
    • 0016412950 scopus 로고
    • The chemical effects of nucleic acids alkylation and their relation to mutagenesis and carcinogenesis
    • Singer, B. 1975. The chemical effects of nucleic acids alkylation and their relation to mutagenesis and carcinogenesis. Prog. Nucleic Acid Res. Mol. Biol. 15:219-284.
    • (1975) Prog. Nucleic Acid Res. Mol. Biol. , vol.15 , pp. 219-284
    • Singer, B.1
  • 74
    • 0028061674 scopus 로고
    • Signal transduction by tumor necrosis factor mediated by JNK protein kinases
    • Sluss, H. K., T. Barrett, B. Dérijard, and R. J. Davis. 1994. Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol. Cell. Biol. 14:8376-8384.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8376-8384
    • Sluss, H.K.1    Barrett, T.2    Dérijard, B.3    Davis, R.J.4
  • 75
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal, T., B. Binetruy, D. A. Mercola, M. Birrer, and M. Karin. 1991. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494-496.
    • (1991) Nature , vol.354 , pp. 494-496
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 76
  • 78
    • 0029770721 scopus 로고    scopus 로고
    • Activation of Pyk2 by stress signals and coupling with JNK signaling pathway
    • Tokiwa, G., I. Dikic, S. Lev, and J. Schlessinger. 1996. Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science 273:792-794.
    • (1996) Science , vol.273 , pp. 792-794
    • Tokiwa, G.1    Dikic, I.2    Lev, S.3    Schlessinger, J.4
  • 80
    • 0029030855 scopus 로고
    • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-Jun induction in response to genotoxic agents
    • van Dam, H., D. Wilhelm, I. Herr, A. Steffen, P. Herrlich, and P. Angel. 1995. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-Jun induction in response to genotoxic agents. EMBO J. 14:1798-1811.
    • (1995) EMBO J. , vol.14 , pp. 1798-1811
    • Van Dam, H.1    Wilhelm, D.2    Herr, I.3    Steffen, A.4    Herrlich, P.5    Angel, P.6
  • 81
    • 0029145073 scopus 로고
    • Rho family members: Activators of MAP kinase cascades
    • Vojtek, A. B., and J. A. Cooper. 1995. Rho family members: activators of MAP kinase cascades. Cell 82:527-529.
    • (1995) Cell , vol.82 , pp. 527-529
    • Vojtek, A.B.1    Cooper, J.A.2
  • 82
    • 0028130213 scopus 로고
    • Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase
    • Westwick, J. K., C. Weitzel, A. Minden, M. Karin, and D. A. Brenner. 1994. Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269:26396-26401.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26396-26401
    • Westwick, J.K.1    Weitzel, C.2    Minden, A.3    Karin, M.4    Brenner, D.A.5
  • 83
    • 0029125757 scopus 로고
    • Integration of MAP kinase signal transduction pathways at the serum response element
    • Whitmarsh, A. J., P. Shore, A. D. Sharrocks, and R. J. Davis. 1995. Integration of MAP kinase signal transduction pathways at the serum response element. Science 269:403-407.
    • (1995) Science , vol.269 , pp. 403-407
    • Whitmarsh, A.J.1    Shore, P.2    Sharrocks, A.D.3    Davis, R.J.4
  • 85
    • 0028670788 scopus 로고
    • Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
    • Yan, M., T. Dai, J. C. Deak, J. M. Kyriakis, L. I. Zon, J. R. Woodgett, and D. J. Templeton. 1994. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature 372:798-800.
    • (1994) Nature , vol.372 , pp. 798-800
    • Yan, M.1    Dai, T.2    Deak, J.C.3    Kyriakis, J.M.4    Zon, L.I.5    Woodgett, J.R.6    Templeton, D.J.7
  • 86
    • 0025090695 scopus 로고
    • Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: Reversal by suramin
    • Yayon. A., and M. Klagsbrun. 1990. Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin. Proc. Natl. Acad. Sci. USA 87:5346-5350.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5346-5350
    • Yayon, A.1    Klagsbrun, M.2
  • 87
    • 0029147738 scopus 로고
    • Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase pathways that converge on Elk-1
    • Zinck. R., M. A. Cahill, M. Kracht, C. Sachsenmaier, R. A. Hipskind. and A. Nordheim. 1995. Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase pathways that converge on Elk-1. Mol. Cell. Biol. 15:4930-4938.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4930-4938
    • Zinck, R.1    Cahill, M.A.2    Kracht, M.3    Sachsenmaier, C.4    Hipskind, R.A.5    Nordheim, A.6


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