Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of appptosis signal-regulating kinase 1

Biochemical Journal

Volumn 373, Issue 3, 2003, Pages 845-853

  Song, Jae J ^a   Lee, Yong J ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Apoptosis signal regulating kinase 1; Glucose deprivation; Glutaredoxin; Glutathione; Metabolic oxidative stress; Thioredoxin

Indexed keywords

DISSOCIATION; ENZYMES; METABOLISM; OXIDATION; REDOX REACTIONS; TOXICITY;

GLUCOSE DEPRIVATION;

BIOCHEMISTRY;

APOPTOSIS SIGNAL REGULATING KINASE 1; BUTHIONINE SULFOXIMINE; GLUCOSE; GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C JUN; SCAVENGER; STRESS ACTIVATED PROTEIN KINASE; THIOREDOXIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISSOCIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENOVIRIDAE; BUTHIONINE SULFOXIMINE; CATALASE; ENZYME ACTIVATION; GENETIC VECTORS; GLUCOSE; HUMANS; MALE; MAP KINASE KINASE KINASE 5; MAP KINASE KINASE KINASES; OXIDATIVE STRESS; OXIDOREDUCTASES; PROTEINS; THIOREDOXIN; TUMOR CELLS, CULTURED;

EID: 0042068217     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030275     Document Type: Article

References (41)

1. Lee, Y. J., Galoforo, S. S., Berns, C. M., Chen, J. C., Davis, B. H., Sim, J. E., Corry, P. M. and Spitz, D. R. (1998) Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells. J. Biol. Chem. 273, 5294-5299
2. Lee, Y. J., Chen, J. C., Amoscato, A. A., Bennouna, J., Spitz, D. R., Suntharalingam, M. and Rhee, J. G. (2001) Protective role of Bcl-2 in metabolic oxidative stress-induced cell death. J. Cell Sci. 114, 677-684
3. Lee, Y. J., Galoforo, S. S., Sim, J. E., Ridnour, L. A., Choi, J., Forman, H. J., Corry, P. M. and Spitz, D. R. (2000) Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in a human breast carcinoma cell line. Free Radical Biol. Med. 28, 575-584
4. 2-terminal kinase. J. Biol. Chem. 273, 29857-29863
5. Toone, W. M., Morgan, B. A. and Jones, N. (2001) Redox control of AP-1-like factors in yeast and beyond. Oncogene 20, 2336-2346
6. 2 sensing through oxidation of the Yap1 transcription factor. EMBO J. 19, 5157-5166
7. Zheng, M., Åslund, F. and Storz, G. (1998) Activation of the OxyR transcription factor by reversible disulfide bond formation. Science 279, 1718-1721
8. Ding, H. and Demple, B. (1997) In vivo kinetics of a redox-regulated transcriptional switch. Proc. Natl. Acad. Sci. U.S.A. 94, 8445-8449
9. Nunoshiba, T., deRojas-Walker, T., Wishnok, J. S., Tannenbaum, S. R. and Demple, B. (1993) Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages. Proc. Natl. Acad. Sci. U.S.A. 90, 9993-9997
10. Hidalgo, E. and Demple, B. (1994) An iron-sulfur center essential for transcriptional activation by the redox-sensing SoxR protein. EMBO J. 13, 138-146
11. Hidalgo, E. and Demple, B. (1996) Activation of SoxR-dependent transcription in vitro by noncatalytic or NifS-mediated assembly of [2Fe-2S] clusters into apo-SoxR. J. Biol. Chem. 271, 7269-7272
12. Bradley, T. M., Hidalgo, E., Leautaud, V., Ding, H. and Demple, B. (1997) Cysteine-to-alanine replacements in the Escherichia coli SoxR protein and the role of the [2Fe-2S] centers in transcriptional activation. Nucleic Acids Res. 25, 1469-1475
13. Hidalgo, E., Ding, H. and Demple, B. (1997) Redox signal transduction via iron-sulfur clusters in the SoxR transcription activator. Trends Biochem. Sci. 22, 207-210
14. Holmgren, A. (1989) Thioredoxin and glutaredoxin systems. J. Biol. Chem. 264, 13963-13966
15. Padilla, C. A., Martinez-Galiseo, E., Barcena, J. A., Spyrou, G. and Holmgren, A. (1995) Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin. Eur. J. Biochem. 227, 27-34
16. Ichijo, H., Nishida, E., Irie, K., Dijke, P., Saitoh, M., Moriguchi, T., Takagi, M., Matsumoto, K., Miyazono, K. and Gotoh, Y. (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275, 90-94
17. Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K. and Ichijo, H. (1998) Mammalian thioredoxin is direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17, 2596-2606
18. 2. J. Biol. Chem. 277, 46566-46575
19. Chrestensen, C. A., Starke, D. W. and Mieyal, J. J. (2000) Acute cadmium exposure inactivates thioltransferase (glutaredoxin), inhibits intracellular reduction of protein-glutathione mixed disulfides and initiates apoptosis. J. Biol. Chem. 275, 26556-28565
20. Yang, Y., Jao, S. C., Nanduri, S., Starke, D., Mieyal, J. J. and Qin, J. (1998) Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity. Biochemistry 37, 17145-17156
21. Takemoto, T., Zhang, Q.-M. and Yonei, S. (1998) Different mechanisms of thioredoxin in its reduced and oxidized forms in defense against hydrogen peroxide in Escherichia coli. Free Radical Biol. Med. 24, 556-562
22. Ehrhart, J. and Zeevark, G. D. (2001) Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures. J. Neurochem. 77, 1496-1507
23. Hall, A. G. (1999)The role of glutathione in the regulation of apoptosis. Eur. J. Clin. Invest. 29, 238-245
24. Wüllner U., Seyfried, J., Groscurth, P., Beinroth, S., Winter, S., Gleichmann, M., Heneka, M., Löschmann, P. A., Schulz, J. B., Weller, M. et al. (1999) Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function. Brain Res. 826, 53-62
25. Griffith, O. W. (1982) Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, protein inhibitors of glutathione synthesis. J. Biol. Chem. 257, 13704-13712
26. Wilhelm, D., Bender, K., Knebel, A. and Anger, P. (1997) The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol. Cell. Biol. 17, 4792-4800
27. Hardy, S., Kitamura, M., Harris-Stansil, T., Dai, Y. and Phipps, M. L. (1997) Construction of adenovirus vectors through Cre-lox recombination. J. Virol. 71, 1842-1849
28. 2-terminal kinase (JNK) and p38. J. Biol. Chem. 273, 22681-22692
29. Kirsch, J. D., Yi, A.-K., Spitz, D. R. and Krieg, A. M. (2002) Accumulation of glutathione disulfide mediates NF-κB activation during immune stimulation with CpG DNA. Antisense Nucleic Acid Drug Dev. 12, 327-340
30. Tobiume, K., Matsuzawa, A., Takahashi, T., Nishtoh, H., Morita, K., Takeda, K., Minowa, O., Miyazono, K., Noda, T. and Ichijo, H. (2001) ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2, 222-228
31. Blackburn, R. V., Spitz, D. R., Liu, X., Galoforo, S. S., Sim, J. E., Ridnour, L. A., Chen, J. C., Davis, B. H., Corry, P. M. and Lee, Y. J. (1999) Metabolic oxidative stress activates signal transduction and gene expression during glucose deprivation in human tumor cells. Free Radical Biol. Med. 26, 419-430
32. Kamata, H. and Hirata, H. (1999) Redox regulation of cellular signaling. Cell. Signal. 11, 1-14
33. Mitsui, A., Hirakawa, T. and Yodoi, J. (1992) Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin. Biochem. Biophys. Res. Commun. 186, 1220-1226
34. Chandra, J., Samali, A. and Orrenius, S. (2000) Triggering and modulation of apoptosis by oxidative stress. Free Radical Biol. Med. 29, 323-333
35. Sato, N., Iwata, S., Nakamura, K., Hori, T., Mori, K. and Yodoi, J. (1995) Thiol-mediated redox regulation of apoptosis. J. Immunol. 154, 3194-3203
36. Liu, H., Nishitoh, H., Ichijo, H. and Kyriakis, J. M. (2000) Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin. Mol. Cell. Biol. 20, 2198-2208
37. Chang, H. Y., Nishitoh, H., Yang, X., Ichijo, H. and Baltimore, D. (1998) Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 281, 1860-1863
38. Chang, H. Y., Yang, X. and Baltimore, D. (1999) Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proc. Natl. Acad. Sci. U.S.A. 96, 1252-1256
39. Ko, Y. G., Kang, Y. S., Park, H., Seol, W., Kim, J., Kim, T., Park, H. S., Choi, E. J. and Kim, S. (2001) Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm. J. Biol. Chem. 276, 39103-39106
40. Yang, X., Khosravi-Far, R., Chang, H. Y. and Baltimore, D. (1997) Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell (Cambridge, Mass.) 89, 1067-1076
41. Zhang, L., Chen, J. and Fu, H. (1999) Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proc. Natl. Acad. Sci. U.S.A. 96, 8511-8515