Confronting high-throughput protein refolding using high pressure and solution screens

Protein Expression and Purification

Volumn 55, Issue 2, 2007, Pages 209-224

  Qoronfleh, M Walid ^a   Hesterberg, Lyndal K ^b   Seefeldt, Matthew B ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b BaroFold Inc   (United States)

Author keywords

Aggregation; Automation; Fractional factorial screen; High hydrostatic pressure; High throughput; Inclusion bodies; Misfolding; Protein recovery; Protein refolding; Small molecules assisted refolding; Solubilization; Structural genomics

Indexed keywords

RECOMBINANT PROTEIN;

ESCHERICHIA COLI; GENETICS; METABOLISM; PRESSURE; PROTEIN FOLDING; REVIEW; SOLUTION AND SOLUBILITY;

ESCHERICHIA COLI; PRESSURE; PROTEIN FOLDING; RECOMBINANT PROTEINS; SOLUTIONS;

ESCHERICHIA COLI;

EID: 34548456411     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2007.05.014     Document Type: Review

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