메뉴 건너뛰기




Volumn 3, Issue 3, 2007, Pages 200-208

Oxidative stress in the pathogenesis/treatment of atherosclerosis

Author keywords

Antioxidants; Atherosclerosis; Oxidative stress; Reactive oxygen species

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; ATORVASTATIN; BIOLOGICAL MARKER; DNA; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ISOPROSTANE DERIVATIVE; LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; XANTHINE OXIDASE;

EID: 34547924845     PISSN: 15734013     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340107781369189     Document Type: Review
Times cited : (2)

References (130)
  • 1
    • 0019812319 scopus 로고
    • Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: Recognition by receptors for acetylated low density lipoproteins
    • Henriksen T, Mahoney EM, Steinberg D. Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins. Proc Nat Acad Sci USA 1981; 78: 6499-6503.
    • (1981) Proc Nat Acad Sci USA , vol.78 , pp. 6499-6503
    • Henriksen, T.1    Mahoney, E.M.2    Steinberg, D.3
  • 2
    • 0037414088 scopus 로고    scopus 로고
    • Antioxidants, statins, and atherosclerosis
    • Gotto AM. Antioxidants, statins, and atherosclerosis. J Am Coll Cardiol 2003; 41: 1205-1210.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1205-1210
    • Gotto, A.M.1
  • 3
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. New Engl J Med 1989; 320: 915-924.
    • (1989) New Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 4
    • 0004968087 scopus 로고
    • Low density lipoprotein undergoes oxidative modification in vivo
    • Palinski W, Rosenfeld ME, Yla-Herttuala S, et al. Low density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci USA 1989; 86: 1372-1376.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1372-1376
    • Palinski, W.1    Rosenfeld, M.E.2    Yla-Herttuala, S.3
  • 5
    • 0037197722 scopus 로고    scopus 로고
    • Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
    • Steinberg D, Witztum JL. Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation 2002: 105: 2107-2111.
    • (2002) Circulation , vol.105 , pp. 2107-2111
    • Steinberg, D.1    Witztum, J.L.2
  • 6
    • 14944363121 scopus 로고    scopus 로고
    • Vitamin E for the treatment of cardiovascular disease: Is there a future?
    • Violi F, Cangemi R, Sabatino G, Pignatelli P. Vitamin E for the treatment of cardiovascular disease: is there a future? Ann N Y Acad Sci 2004; 1031: 292-304.
    • (2004) Ann N Y Acad Sci , vol.1031 , pp. 292-304
    • Violi, F.1    Cangemi, R.2    Sabatino, G.3    Pignatelli, P.4
  • 7
    • 0038160993 scopus 로고    scopus 로고
    • Beyond LDL oxidation: ROS in vascular signal transduction
    • Chen K, Thomas SR, Keaney JF Jr. Beyond LDL oxidation: ROS in vascular signal transduction. Free Radic Biol Med 2003; 35: 117-132.
    • (2003) Free Radic Biol Med , vol.35 , pp. 117-132
    • Chen, K.1    Thomas, S.R.2    Keaney Jr., J.F.3
  • 8
    • 0017305294 scopus 로고
    • The pathogenesis of atherosclerosis (first of two parts)
    • Ross R, Glomset JA. The pathogenesis of atherosclerosis (first of two parts). New Engl J Med 1976; 295: 369-377.
    • (1976) New Engl J Med , vol.295 , pp. 369-377
    • Ross, R.1    Glomset, J.A.2
  • 9
    • 0017184071 scopus 로고
    • The pathogenesis of atherosclerosis (second of two parts)
    • Ross R, Glomset JA. The pathogenesis of atherosclerosis (second of two parts). New Engl J Med 1976; 295: 420-425.
    • (1976) New Engl J Med , vol.295 , pp. 420-425
    • Ross, R.1    Glomset, J.A.2
  • 11
    • 25144453937 scopus 로고    scopus 로고
    • NADPH oxidase and endothelial cell function
    • Ray R, Shah AM. NADPH oxidase and endothelial cell function. Clin Sci (Lond) 2005; 109: 217-226.
    • (2005) Clin Sci (Lond) , vol.109 , pp. 217-226
    • Ray, R.1    Shah, A.M.2
  • 12
    • 0030453086 scopus 로고    scopus 로고
    • Assembly of the phagocyte NADPH oxidase: Molecular interaction of oxidase proteins
    • DeLeo FR, Quinn MT. Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins. J Leukoc Biol 1996; 60: 677-691.
    • (1996) J Leukoc Biol , vol.60 , pp. 677-691
    • DeLeo, F.R.1    Quinn, M.T.2
  • 13
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74: 1141-1148.
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 14
    • 0033897196 scopus 로고    scopus 로고
    • Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells
    • Bayraktutan U, Blayney L, Shah AM. Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells. Arterioscler Thromb Vasc Biol 2000; 20: 1903-1911.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1903-1911
    • Bayraktutan, U.1    Blayney, L.2    Shah, A.M.3
  • 15
    • 0034617071 scopus 로고    scopus 로고
    • A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
    • Gorlach A, Brandes RP, Nguyen K, Amidi M, Dehghani F, Busse R. A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circ Res 2000; 87: 26-32.
    • (2000) Circ Res , vol.87 , pp. 26-32
    • Gorlach, A.1    Brandes, R.P.2    Nguyen, K.3    Amidi, M.4    Dehghani, F.5    Busse, R.6
  • 16
    • 0034617020 scopus 로고    scopus 로고
    • Vascular gp91(phox): Beyond the endothelium
    • Pagano PJ. Vascular gp91(phox): beyond the endothelium. Circ Res 2000: 87: 1-3.
    • (2000) Circ Res , vol.87 , pp. 1-3
    • Pagano, P.J.1
  • 17
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev 2004; 4: 181-189.
    • (2004) Nat Rev , vol.4 , pp. 181-189
    • Lambeth, J.D.1
  • 18
    • 28344444371 scopus 로고    scopus 로고
    • New insights on oxidative stress in the artery wall
    • Stocker R, Keaney JF Jr. New insights on oxidative stress in the artery wall. J Thromb Haemost 2005; 3: 1825-1834.
    • (2005) J Thromb Haemost , vol.3 , pp. 1825-1834
    • Stocker, R.1    Keaney Jr., J.F.2
  • 19
    • 0031443873 scopus 로고    scopus 로고
    • Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
    • Pagano PJ, Clark JK, Cifuentes-Pagano ME, Clark SM, Callis GM, Quinn MT. Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II. Proc Natl Acad Sci USA 1997; 94: 14483-14488.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14483-14488
    • Pagano, P.J.1    Clark, J.K.2    Cifuentes-Pagano, M.E.3    Clark, S.M.4    Callis, G.M.5    Quinn, M.T.6
  • 20
    • 0036954803 scopus 로고    scopus 로고
    • Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
    • Ushio-Fukai M, Tang Y, Fukai T, et al. Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res 2002; 91: 1160-1167.
    • (2002) Circ Res , vol.91 , pp. 1160-1167
    • Ushio-Fukai, M.1    Tang, Y.2    Fukai, T.3
  • 21
    • 0033586639 scopus 로고    scopus 로고
    • Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
    • Warnholtz A, Nickenig G, Schulz E, et al. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation 1999; 99: 2027-2033.
    • (1999) Circulation , vol.99 , pp. 2027-2033
    • Warnholtz, A.1    Nickenig, G.2    Schulz, E.3
  • 22
  • 23
    • 0034640107 scopus 로고    scopus 로고
    • Vascular superoxide production by NAD(P)H oxidase: Association with endothelial dysfunction and clinical risk factors
    • Guzik TJ, West NE, Black E, et al. Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circ Res 2000; 86: E85-90.
    • (2000) Circ Res , vol.86
    • Guzik, T.J.1    West, N.E.2    Black, E.3
  • 24
    • 0037177164 scopus 로고    scopus 로고
    • Superoxide production and expression of nox family proteins in human atherosclerosis
    • Sorescu D, Weiss D, Lassegue B, et al. Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation 2002; 105: 1429-1435.
    • (2002) Circulation , vol.105 , pp. 1429-1435
    • Sorescu, D.1    Weiss, D.2    Lassegue, B.3
  • 25
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik TJ, Mussa S, Gastaldi D, Sadowski J, Ratnatunga C, Pillai R, Channon KM. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 2002; 105: 1656-1662.
    • (2002) Circulation , vol.105 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 26
    • 27444441677 scopus 로고    scopus 로고
    • Nox1 is involved in angiotensin II-mediated hypertension: A study in Nox1-deficient mice
    • Matsuno K, Yamada H, Iwata K, et al. Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation 2005; 112: 2677-2685.
    • (2005) Circulation , vol.112 , pp. 2677-2685
    • Matsuno, K.1    Yamada, H.2    Iwata, K.3
  • 27
    • 3342983728 scopus 로고    scopus 로고
    • gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension
    • Jung O, Schreiber JG, Geiger H, Pedrazzini T, Busse R, Brandes RP. gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension. Circulation 2004; 109: 1795-1801.
    • (2004) Circulation , vol.109 , pp. 1795-1801
    • Jung, O.1    Schreiber, J.G.2    Geiger, H.3    Pedrazzini, T.4    Busse, R.5    Brandes, R.P.6
  • 28
    • 33745066138 scopus 로고    scopus 로고
    • Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: Implication of the NAD(P)H oxidase pathway
    • Otto A, Fontaine J, Tschirhart E, Fontaine D, Berkenboom G. Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: implication of the NAD(P)H oxidase pathway. Br J Pharmacol 2006; 148: 544-552.
    • (2006) Br J Pharmacol , vol.148 , pp. 544-552
    • Otto, A.1    Fontaine, J.2    Tschirhart, E.3    Fontaine, D.4    Berkenboom, G.5
  • 29
    • 2642510689 scopus 로고    scopus 로고
    • Reoxygenation-induced constriction in murine coronary arteries: The role of endothelial NADPH oxidase (gp91phox) and intracellular superoxide
    • Liu JQ, Zelko IN, Folz RJ. Reoxygenation-induced constriction in murine coronary arteries: the role of endothelial NADPH oxidase (gp91phox) and intracellular superoxide. J Biol Chem 2004; 279: 24493-24497.
    • (2004) J Biol Chem , vol.279 , pp. 24493-24497
    • Liu, J.Q.1    Zelko, I.N.2    Folz, R.J.3
  • 30
    • 33746803850 scopus 로고    scopus 로고
    • Nox2 is determinant for ischemia-induced oxidative stress and arterial vasodilatation: A pilot study in patients with hereditary Nox2 deficiency
    • Violi F, Sanguigni V, Loffredo L, et al. Nox2 is determinant for ischemia-induced oxidative stress and arterial vasodilatation: a pilot study in patients with hereditary Nox2 deficiency. Arterioscler Thromb Vasc Biol 2006; 26: e131-132.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26
    • Violi, F.1    Sanguigni, V.2    Loffredo, L.3
  • 31
    • 0028292033 scopus 로고
    • Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
    • Daugherty A, Dunn JL, Rateri DL, Heinecke JW. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J Clin Invest 1994; 94: 437-444.
    • (1994) J Clin Invest , vol.94 , pp. 437-444
    • Daugherty, A.1    Dunn, J.L.2    Rateri, D.L.3    Heinecke, J.W.4
  • 32
    • 0034659164 scopus 로고    scopus 로고
    • Myeloperoxidase-generated oxidants and atherosclerosis
    • Podrez EA, Abu-Soud HM, Hazen SL. Myeloperoxidase-generated oxidants and atherosclerosis. Free Radic Biol Med 2000; 28: 1717-1725.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1717-1725
    • Podrez, E.A.1    Abu-Soud, H.M.2    Hazen, S.L.3
  • 33
    • 0028030788 scopus 로고
    • Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation
    • Hazell LJ, van den Berg JJ, Stocker R. Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation. Biochem J 1994; 302 (Pt 1): 297-304.
    • (1994) Biochem J , vol.302 , Issue.PART 1 , pp. 297-304
    • Hazell, L.J.1    van den Berg, J.J.2    Stocker, R.3
  • 34
    • 0035798684 scopus 로고    scopus 로고
    • Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase
    • Fu X, Kassim SY, Parks WC, Heinecke JW. Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. J Biol Chem 2001; 276: 41279-41287.
    • (2001) J Biol Chem , vol.276 , pp. 41279-41287
    • Fu, X.1    Kassim, S.Y.2    Parks, W.C.3    Heinecke, J.W.4
  • 35
    • 0035108136 scopus 로고    scopus 로고
    • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
    • Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P. Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol 2001; 158: 879-891.
    • (2001) Am J Pathol , vol.158 , pp. 879-891
    • Sugiyama, S.1    Okada, Y.2    Sukhova, G.K.3    Virmani, R.4    Heinecke, J.W.5    Libby, P.6
  • 36
    • 0036493406 scopus 로고    scopus 로고
    • Defects in leukocyte-mediated initiation of lipid peroxidation in plasma as studied in myeloperoxidase-deficient subjects: Systematic identification of multiple endogenous diffusible substrates for myeloperoxidase in plasma
    • Zhang R, Shen Z, Nauseef WM, Hazen SL. Defects in leukocyte-mediated initiation of lipid peroxidation in plasma as studied in myeloperoxidase-deficient subjects: systematic identification of multiple endogenous diffusible substrates for myeloperoxidase in plasma. Blood 2002; 99: 1802-1810.
    • (2002) Blood , vol.99 , pp. 1802-1810
    • Zhang, R.1    Shen, Z.2    Nauseef, W.M.3    Hazen, S.L.4
  • 37
    • 0037195783 scopus 로고    scopus 로고
    • Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation
    • Zhang R, Brennan ML, Shen Z, et al. Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation. J Biol Chem 2002; 277: 46116-46122.
    • (2002) J Biol Chem , vol.277 , pp. 46116-46122
    • Zhang, R.1    Brennan, M.L.2    Shen, Z.3
  • 38
    • 0035824162 scopus 로고    scopus 로고
    • Association between myeloperoxidase levels and risk of coronary artery disease
    • Zhang R, Brennan ML, Fu X, et al. Association between myeloperoxidase levels and risk of coronary artery disease. JAMA 2001; 286: 2136-2142.
    • (2001) JAMA , vol.286 , pp. 2136-2142
    • Zhang, R.1    Brennan, M.L.2    Fu, X.3
  • 40
    • 0034904840 scopus 로고    scopus 로고
    • A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians
    • Nikpoor B, Turecki G, Fournier C, Theroux P, Rouleau GA. A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians. Am Heart J 2001; 142: 336-339.
    • (2001) Am Heart J , vol.142 , pp. 336-339
    • Nikpoor, B.1    Turecki, G.2    Fournier, C.3    Theroux, P.4    Rouleau, G.A.5
  • 41
    • 0043166521 scopus 로고    scopus 로고
    • Statins promote potent systemic antioxidant effects through specific inflammatory pathways
    • Shishehbor MH, Brennan ML, Aviles RJ, et al. Statins promote potent systemic antioxidant effects through specific inflammatory pathways. Circulation 2003; 108: 426-431.
    • (2003) Circulation , vol.108 , pp. 426-431
    • Shishehbor, M.H.1    Brennan, M.L.2    Aviles, R.J.3
  • 42
    • 0037105296 scopus 로고    scopus 로고
    • Structure and function of xanthine oxidoreductase: Where are we now?
    • Harrison R. Structure and function of xanthine oxidoreductase: where are we now? Free Radic Biol Med 2002; 33: 774-797.
    • (2002) Free Radic Biol Med , vol.33 , pp. 774-797
    • Harrison, R.1
  • 43
    • 0021984681 scopus 로고
    • Oxygen-derived free radicals in postischemic tissue injury
    • McCord JM. Oxygen-derived free radicals in postischemic tissue injury. New Engl J Med 1985; 312: 159-163.
    • (1985) New Engl J Med , vol.312 , pp. 159-163
    • McCord, J.M.1
  • 44
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 1993: 91: 2546-2551.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 45
    • 0030750723 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients
    • Cardillo C, Kilcoyne CM, Cannon RO, 3rd, Quyyumi AA, Panza JA. Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients. Hypertension 1997; 30: 57-63.
    • (1997) Hypertension , vol.30 , pp. 57-63
    • Cardillo, C.1    Kilcoyne, C.M.2    Cannon 3rd, R.O.3    Quyyumi, A.A.4    Panza, J.A.5
  • 46
    • 0037469205 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers
    • Guthikonda S, Sinkey C, Barenz T, Haynes WG. Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers. Circulation 2003; 107: 416-421.
    • (2003) Circulation , vol.107 , pp. 416-421
    • Guthikonda, S.1    Sinkey, C.2    Barenz, T.3    Haynes, W.G.4
  • 47
    • 0037453094 scopus 로고    scopus 로고
    • Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: Relation to endothelium-dependent vasodilation
    • Spiekermann S, Landmesser U, Dikalov S, Bredt M, Gamez G, Tatge H, Reepschlager N, Hornig B, Drexler H, Harrison DG. Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 2003; 107: 1383-1389.
    • (2003) Circulation , vol.107 , pp. 1383-1389
    • Spiekermann, S.1    Landmesser, U.2    Dikalov, S.3    Bredt, M.4    Gamez, G.5    Tatge, H.6    Reepschlager, N.7    Hornig, B.8    Drexler, H.9    Harrison, D.G.10
  • 48
    • 0026515846 scopus 로고
    • Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells
    • Dupont GP, Huecksteadt TP, Marshall BC, Ryan US, Michael JR, Hoidal JR. Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells. J Clin Invest 1992: 89: 197-202.
    • (1992) J Clin Invest , vol.89 , pp. 197-202
    • Dupont, G.P.1    Huecksteadt, T.P.2    Marshall, B.C.3    Ryan, U.S.4    Michael, J.R.5    Hoidal, J.R.6
  • 49
    • 0028899207 scopus 로고
    • Conversion of xanthine dehydrogenase to xanthine oxidase in bovine carotid artery endothelial cells induced by activated neutrophils: Involvement of adhesion molecules
    • Wakabayashi Y, Fujita H, Morita I, Kawaguchi H, Murota S. Conversion of xanthine dehydrogenase to xanthine oxidase in bovine carotid artery endothelial cells induced by activated neutrophils: involvement of adhesion molecules. Biochim Biophys Acta 1995; 1265: 103-109.
    • (1995) Biochim Biophys Acta , vol.1265 , pp. 103-109
    • Wakabayashi, Y.1    Fujita, H.2    Morita, I.3    Kawaguchi, H.4    Murota, S.5
  • 50
    • 0029758908 scopus 로고    scopus 로고
    • Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits
    • White CR, Darley-Usmar V, Berrington WR, et al. Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits. Proc Natl Acad Sci USA 1996; 93: 8745-8749.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8745-8749
    • White, C.R.1    Darley-Usmar, V.2    Berrington, W.R.3
  • 51
    • 0035336436 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation
    • Wang Q, Doerschuk CM. The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation. J Immunol 2001; 166: 6877-6884.
    • (2001) J Immunol , vol.166 , pp. 6877-6884
    • Wang, Q.1    Doerschuk, C.M.2
  • 52
    • 0037155054 scopus 로고    scopus 로고
    • Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart
    • Saavedra WF, Paolocci N, St John ME, et al. Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart. Circ Res 2002; 90: 297-304.
    • (2002) Circ Res , vol.90 , pp. 297-304
    • Saavedra, W.F.1    Paolocci, N.2    St John, M.E.3
  • 53
    • 33750475625 scopus 로고    scopus 로고
    • Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells
    • Gutierrez J, Ballinger SW, Darley-Usmar VM, Landar A. Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells. Circ Res 2006; 99: 924-932.
    • (2006) Circ Res , vol.99 , pp. 924-932
    • Gutierrez, J.1    Ballinger, S.W.2    Darley-Usmar, V.M.3    Landar, A.4
  • 54
    • 1842375100 scopus 로고    scopus 로고
    • Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis
    • Quillet-Mary A, Jaffrezou JP, Mansat V, Bordier C, Naval J, Laurent G. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J Biol Chem 1997; 272: 21388-21395.
    • (1997) J Biol Chem , vol.272 , pp. 21388-21395
    • Quillet-Mary, A.1    Jaffrezou, J.P.2    Mansat, V.3    Bordier, C.4    Naval, J.5    Laurent, G.6
  • 55
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci USA 2000; 97: 12222-12226.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12222-12226
    • XL, D.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6    Wu, J.7    Brownlee, M.8
  • 56
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T, Edelstein D, Du XL, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000; 404: 787-790.
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3
  • 57
    • 0037199466 scopus 로고    scopus 로고
    • Mitochondrial integrity and function in atherogenesis
    • Ballinger SW, Patterson C, Knight-Lozano CA, et al. Mitochondrial integrity and function in atherogenesis. Circulation 2002; 106: 544-549.
    • (2002) Circulation , vol.106 , pp. 544-549
    • Ballinger, S.W.1    Patterson, C.2    Knight-Lozano, C.A.3
  • 59
    • 0032482975 scopus 로고    scopus 로고
    • Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
    • Vasquez-Viva J, Kalyanaraman B, Martasek P, et al. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA 1998; 95: 9220-9225.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9220-9225
    • Vasquez-Viva, J.1    Kalyanaraman, B.2    Martasek, P.3
  • 60
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem 1998; 273: 25804-25808.
    • (1998) J Biol Chem , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 61
    • 27444440478 scopus 로고    scopus 로고
    • Oxidative stress and the vascular wall: NADPH oxidases take center stage
    • Keaney JF, Jr. Oxidative stress and the vascular wall: NADPH oxidases take center stage. Circulation 2005; 112: 2585-2588.
    • (2005) Circulation , vol.112 , pp. 2585-2588
    • Keaney Jr., J.F.1
  • 62
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004; 84: 1381-1478.
    • (2004) Physiol Rev , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney Jr, J.F.2
  • 63
    • 0034696590 scopus 로고    scopus 로고
    • Vascular effects following homozygous disruption of p47(phox): An essential component of NADPH oxidase
    • Hsich E, Segal BH, Pagano PJ, et al. Vascular effects following homozygous disruption of p47(phox): An essential component of NADPH oxidase. Circulation 2000; 101: 1234-1236.
    • (2000) Circulation , vol.101 , pp. 1234-1236
    • Hsich, E.1    Segal, B.H.2    Pagano, P.J.3
  • 64
    • 0029133481 scopus 로고
    • Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
    • Pritchard KA Jr, Groszek L, Smalley DM, et al. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res 1995; 77: 510-518.
    • (1995) Circ Res , vol.77 , pp. 510-518
    • Pritchard Jr, K.A.1    Groszek, L.2    Smalley, D.M.3
  • 65
    • 0035814951 scopus 로고    scopus 로고
    • Endothelial regulation of vasomotion in apoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin
    • Laursen JB, Somers M, Kurz S, et al. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation 2001; 103: 1282-1288.
    • (2001) Circulation , vol.103 , pp. 1282-1288
    • Laursen, J.B.1    Somers, M.2    Kurz, S.3
  • 66
    • 0035793616 scopus 로고    scopus 로고
    • Mechanisms underlying endothelial dysfunction in diabetes mellitus
    • Hink U, Li H, Mollnau H, et al. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 2001; 88: E14-22.
    • (2001) Circ Res , vol.88
    • Hink, U.1    Li, H.2    Mollnau, H.3
  • 67
    • 0033913195 scopus 로고    scopus 로고
    • Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation
    • Bloodsworth A, O'Donnell VB, Freeman BA. Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation. Arterioscl Thromb Vasc Biol 2000; 20: 1707-1715.
    • (2000) Arterioscl Thromb Vasc Biol , vol.20 , pp. 1707-1715
    • Bloodsworth, A.1    O'Donnell, V.B.2    Freeman, B.A.3
  • 69
    • 33847612773 scopus 로고    scopus 로고
    • Biomarkers of atherosclerotic plaque instability and rupture
    • Koenig W, Khuseyinova N. Biomarkers of atherosclerotic plaque instability and rupture. Arterioscler Thromb Vasc Biol 2007; 27: 15-26.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 15-26
    • Koenig, W.1    Khuseyinova, N.2
  • 70
    • 0035901607 scopus 로고    scopus 로고
    • Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk
    • Tsimikas S, Witztum JL. Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk. Circulation 2001; 103: 1930-1932.
    • (2001) Circulation , vol.103 , pp. 1930-1932
    • Tsimikas, S.1    Witztum, J.L.2
  • 71
    • 0029898072 scopus 로고    scopus 로고
    • Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2
    • Pratico D, FitzGerald GA. Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2. J Biol Chem 1996; 271: 8919-8924.
    • (1996) J Biol Chem , vol.271 , pp. 8919-8924
    • Pratico, D.1    FitzGerald, G.A.2
  • 72
    • 0031752607 scopus 로고    scopus 로고
    • Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice
    • Pratico D, Tangirala RK, Rader DJ, Rokach J, FitzGerald GA. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nat Med 1998; 4: 1189-1192.
    • (1998) Nat Med , vol.4 , pp. 1189-1192
    • Pratico, D.1    Tangirala, R.K.2    Rader, D.J.3    Rokach, J.4    FitzGerald, G.A.5
  • 73
    • 0030611766 scopus 로고    scopus 로고
    • Localization of distinct F2-isoprostanes in human atherosclerotic lesions
    • Pratico D, Iuliano L, Mauriello A, et al. Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest 1997; 100: 2028-2034.
    • (1997) J Clin Invest , vol.100 , pp. 2028-2034
    • Pratico, D.1    Iuliano, L.2    Mauriello, A.3
  • 75
    • 0037164094 scopus 로고    scopus 로고
    • Platelet activation in obese women: Role of inflammation and oxidant stress
    • Davi G, Guagnano MT, Ciabattoni G, et al. Platelet activation in obese women: role of inflammation and oxidant stress. JAMA 2002; 288: 2008-2014.
    • (2002) JAMA , vol.288 , pp. 2008-2014
    • Davi, G.1    Guagnano, M.T.2    Ciabattoni, G.3
  • 76
    • 0037069383 scopus 로고    scopus 로고
    • Low-density lipoprotein level reduction by the 3-hydroxy-3-methyl-glutaryl coenzyme-A inhibitor simvastatin is accompanied by a related reduction of F2-isoprostane formation in hypercholesterolemic subjects: No further effect of vitamin E
    • De Caterina R, Cipollone F, Filardo FP, et al. Low-density lipoprotein level reduction by the 3-hydroxy-3-methyl-glutaryl coenzyme-A inhibitor simvastatin is accompanied by a related reduction of F2-isoprostane formation in hypercholesterolemic subjects: no further effect of vitamin E. Circulation 2002; 106: 2543-2549.
    • (2002) Circulation , vol.106 , pp. 2543-2549
    • De Caterina, R.1    Cipollone, F.2    Filardo, F.P.3
  • 77
    • 20444434019 scopus 로고    scopus 로고
    • Active smoking and a history of smoking are associated with enhanced prostaglandin F(2alpha), interleukin-6 and F2-isoprostane formation in elderly men
    • Helmersson J, Larsson A, Vessby B, Basu S. Active smoking and a history of smoking are associated with enhanced prostaglandin F(2alpha), interleukin-6 and F2-isoprostane formation in elderly men. Atherosclerosis 2005; 181: 201-207.
    • (2005) Atherosclerosis , vol.181 , pp. 201-207
    • Helmersson, J.1    Larsson, A.2    Vessby, B.3    Basu, S.4
  • 78
    • 6344267152 scopus 로고    scopus 로고
    • Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity
    • Hansel B, Giral P, Nobecourt E, et al. Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity. J Clin Endocrinol Metabol 2004; 89: 4963-4971.
    • (2004) J Clin Endocrinol Metabol , vol.89 , pp. 4963-4971
    • Hansel, B.1    Giral, P.2    Nobecourt, E.3
  • 79
    • 0036829579 scopus 로고    scopus 로고
    • Jones DP, Mody VC, Jr., Carlson JL, Lynn MJ, Sternberg P Jr. Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses. Free Radic Biol Med 2002; 33: 1290-1300.
    • Jones DP, Mody VC, Jr., Carlson JL, Lynn MJ, Sternberg P Jr. Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses. Free Radic Biol Med 2002; 33: 1290-1300.
  • 80
    • 0037414194 scopus 로고    scopus 로고
    • Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy
    • Shishehbor MH, Aviles RJ, Brennan ML, et al. Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA 2003; 289: 1675-1680.
    • (2003) JAMA , vol.289 , pp. 1675-1680
    • Shishehbor, M.H.1    Aviles, R.J.2    Brennan, M.L.3
  • 82
    • 13844297589 scopus 로고    scopus 로고
    • Biomarkers of oxidative stress study II: Are oxidation products of lipids, proteins, and DNA markers of CC14 poisoning?
    • Kadiiska MB, Gladen BC, Baird DD, et al. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CC14 poisoning? Free Radic Biol Med 2005; 38: 698-710.
    • (2005) Free Radic Biol Med , vol.38 , pp. 698-710
    • Kadiiska, M.B.1    Gladen, B.C.2    Baird, D.D.3
  • 84
    • 0037133215 scopus 로고    scopus 로고
    • New tools for coronary risk assessment: What are their advantages and limitations?
    • Pearson TA. New tools for coronary risk assessment: what are their advantages and limitations? Circulation 2002; 105: 886-892.
    • (2002) Circulation , vol.105 , pp. 886-892
    • Pearson, T.A.1
  • 85
    • 0029118174 scopus 로고
    • Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production
    • Ohara Y, Peterson TE, Sayegh HS, et al. Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production. Circulation 1995; 92: 898-903.
    • (1995) Circulation , vol.92 , pp. 898-903
    • Ohara, Y.1    Peterson, T.E.2    Sayegh, H.S.3
  • 86
    • 0031471957 scopus 로고    scopus 로고
    • In vivo formation of 8-Epiprostaglandin F2 alpha is increased in hypercholesterolemia
    • Davi G, Alessandrini P, Mezzetti A, et al. In vivo formation of 8-Epiprostaglandin F2 alpha is increased in hypercholesterolemia. Arterioscler Thromb Vasc Biol 1997; 17: 3230-3235.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3230-3235
    • Davi, G.1    Alessandrini, P.2    Mezzetti, A.3
  • 87
    • 0036247193 scopus 로고    scopus 로고
    • Increased superoxide anion production by platelets in hypercholesterolemic patients
    • Sanguigni V, Pignatelli P, Caccese D, et al. Increased superoxide anion production by platelets in hypercholesterolemic patients. Thromb Haemost 2002; 87: 796-801.
    • (2002) Thromb Haemost , vol.87 , pp. 796-801
    • Sanguigni, V.1    Pignatelli, P.2    Caccese, D.3
  • 88
    • 0034123171 scopus 로고    scopus 로고
    • Interactions of oxidants with vascular signaling systems
    • Wolin MS. Interactions of oxidants with vascular signaling systems. Arterioscler Thromb Vasc Biol 2000; 20: 1430-1442.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1430-1442
    • Wolin, M.S.1
  • 89
    • 34547918018 scopus 로고    scopus 로고
    • Carnevale R, Pignatelli P, Lenti L, et al. LDL are oxidatively modified by platelets via GP91phox and accumulate in human monocytes. FASEB J 2006.
    • Carnevale R, Pignatelli P, Lenti L, et al. LDL are oxidatively modified by platelets via GP91phox and accumulate in human monocytes. FASEB J 2006.
  • 90
    • 0033868728 scopus 로고    scopus 로고
    • Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia
    • Ferro D, Parrotto S, Basili S, Alessandri C, Violi F. Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia. J Am Coll Cardiol 2000; 36: 427-431.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 427-431
    • Ferro, D.1    Parrotto, S.2    Basili, S.3    Alessandri, C.4    Violi, F.5
  • 91
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004; 109: 1118-26.
    • (2004) Circulation , vol.109 , pp. 1118-1126
    • Schonbeck, U.1    Libby, P.2
  • 92
    • 0141841612 scopus 로고    scopus 로고
    • High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study
    • Kinlay S, Schwartz GG, Olsson AG, et al. High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study. Circulation 2003; 108: 1560-1566.
    • (2003) Circulation , vol.108 , pp. 1560-1566
    • Kinlay, S.1    Schwartz, G.G.2    Olsson, A.G.3
  • 93
    • 0034682966 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular complications in diabetes: Isoprostanes as new markers on an old paradigm
    • Mezzetti A, Cipollone F, Cuccurullo F. Oxidative stress and cardiovascular complications in diabetes: isoprostanes as new markers on an old paradigm. Cardiovasc Res 2000; 47: 475-488.
    • (2000) Cardiovasc Res , vol.47 , pp. 475-488
    • Mezzetti, A.1    Cipollone, F.2    Cuccurullo, F.3
  • 94
    • 0032031605 scopus 로고    scopus 로고
    • Timimi FK, Ting HH, Haley EA, Roddy MA, Ganz P, Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am College of Cardiol 1998; 31: 552-557.
    • Timimi FK, Ting HH, Haley EA, Roddy MA, Ganz P, Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am College of Cardiol 1998; 31: 552-557.
  • 95
    • 2442708882 scopus 로고    scopus 로고
    • Should antioxidant status be considered in interventional trials with antioxidants?
    • Violi F, Loffredo L, Musella L, Marcoccia A. Should antioxidant status be considered in interventional trials with antioxidants? Heart 2004; 90: 598-602.
    • (2004) Heart , vol.90 , pp. 598-602
    • Violi, F.1    Loffredo, L.2    Musella, L.3    Marcoccia, A.4
  • 96
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino F, Hishikawa K, Katusic ZS, Luscher TF. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 1997; 96: 25-28.
    • (1997) Circulation , vol.96 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Luscher, T.F.4
  • 97
    • 0035725015 scopus 로고    scopus 로고
    • Beswick PA, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat. Hypertens 2001; 38: 1107-1111.
    • Beswick PA, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat. Hypertens 2001; 38: 1107-1111.
  • 98
    • 0034625073 scopus 로고    scopus 로고
    • Investigation into the sources of superoxide in human blood vessels: Angiotensin II increases superoxide production in human internal mammary arteries
    • Berry C, Hamilton CA, Brosnan MJ, et al. Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation 2000; 101: 2206-2212.
    • (2000) Circulation , vol.101 , pp. 2206-2212
    • Berry, C.1    Hamilton, C.A.2    Brosnan, M.J.3
  • 99
    • 0035843914 scopus 로고    scopus 로고
    • Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice
    • Wang HD, Xu S, Johns DG, Du Y, Quinn MT, Cayatte AJ, Cohen RA. Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice. Circ Res 2001; 88: 947-953.
    • (2001) Circ Res , vol.88 , pp. 947-953
    • Wang, H.D.1    Xu, S.2    Johns, D.G.3    Du, Y.4    Quinn, M.T.5    Cayatte, A.J.6    Cohen, R.A.7
  • 100
    • 2642521178 scopus 로고    scopus 로고
    • Enhanced platelet release of superoxide anion in systemic hypertension: Role of AT1 receptors
    • Germano G, Sanguigni V, Pignatelli P, et al. Enhanced platelet release of superoxide anion in systemic hypertension: role of AT1 receptors. J Hypertens 2004; 22: 1151-1156.
    • (2004) J Hypertens , vol.22 , pp. 1151-1156
    • Germano, G.1    Sanguigni, V.2    Pignatelli, P.3
  • 101
    • 0032499667 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
    • Taddei S, Virdis A, Ghiadoni L, Magagna A, Salvetti A. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation 1998; 97: 2222-2229.
    • (1998) Circulation , vol.97 , pp. 2222-2229
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Salvetti, A.5
  • 102
    • 0037342568 scopus 로고    scopus 로고
    • Obesity and systemic oxidative stress: Clinical correlates of oxidative stress in the Framingham Study
    • Keaney JF Jr, Larson MG, Vasan RS, et al. Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 2003; 23: 434-439.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 434-439
    • Keaney Jr, J.F.1    Larson, M.G.2    Vasan, R.S.3
  • 103
    • 0029002677 scopus 로고
    • Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage
    • Morrow JD, Frei B, Longmire AW, et al. Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. N Engl J Med 1995; 332: 1198-1203.
    • (1995) N Engl J Med , vol.332 , pp. 1198-1203
    • Morrow, J.D.1    Frei, B.2    Longmire, A.W.3
  • 104
    • 0032514728 scopus 로고    scopus 로고
    • Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease
    • Holvoet P, Vanhaecke J, Janssens S, Van de Werf F, Collen D. Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation 1998; 98: 1487-1494.
    • (1998) Circulation , vol.98 , pp. 1487-1494
    • Holvoet, P.1    Vanhaecke, J.2    Janssens, S.3    Van de Werf, F.4    Collen, D.5
  • 105
    • 0033789815 scopus 로고    scopus 로고
    • Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease
    • Toshima S, Hasegawa A, Kurabayashi M, et al. Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease. Arterioscler Thromb Vasc Biol 2000; 20: 2243-2247.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2243-2247
    • Toshima, S.1    Hasegawa, A.2    Kurabayashi, M.3
  • 106
    • 0035901582 scopus 로고    scopus 로고
    • Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes
    • Ehara S, Ueda M, Naruko T, et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 2001; 103: 1955-1960.
    • (2001) Circulation , vol.103 , pp. 1955-1960
    • Ehara, S.1    Ueda, M.2    Naruko, T.3
  • 107
    • 0037388739 scopus 로고    scopus 로고
    • Plasma oxidized LDL: A predictor for acute myocardial infarction?
    • Nordin Fredrikson G, Hedblad B, Berglund G, Nilsson J. Plasma oxidized LDL: a predictor for acute myocardial infarction? J Int Med 2003; 253: 425-429.
    • (2003) J Int Med , vol.253 , pp. 425-429
    • Nordin Fredrikson, G.1    Hedblad, B.2    Berglund, G.3    Nilsson, J.4
  • 108
    • 0035039618 scopus 로고    scopus 로고
    • Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease
    • Holvoet P, Mertens A, Verhamme P, et al. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2001; 21: 844-848.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 844-848
    • Holvoet, P.1    Mertens, A.2    Verhamme, P.3
  • 109
    • 0043235639 scopus 로고    scopus 로고
    • Association of high coronary heart disease risk status with circulating oxidized LDL in the well-functioning elderly: Findings from the Health, Aging, and Body Composition study
    • Holvoet P, Harris TB, Tracy RP, et al. Association of high coronary heart disease risk status with circulating oxidized LDL in the well-functioning elderly: findings from the Health, Aging, and Body Composition study. Arterioscler Thromb Vasc Biol 2003; 23: 1444-1448.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1444-1448
    • Holvoet, P.1    Harris, T.B.2    Tracy, R.P.3
  • 110
    • 23244461410 scopus 로고    scopus 로고
    • Plasma oxidized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population
    • Meisinger C, Baumert J, Khuseyinova N, Loewel H, Koenig W. Plasma oxidized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population. Circulation 2005; 112: 651-657.
    • (2005) Circulation , vol.112 , pp. 651-657
    • Meisinger, C.1    Baumert, J.2    Khuseyinova, N.3    Loewel, H.4    Koenig, W.5
  • 111
    • 33644518681 scopus 로고    scopus 로고
    • Increased plasma markers of oxidative stress are associated with coronary heart disease in males with diabetes mellitus and with 10-year risk in a prospective sample of males
    • Stephens JW, Gable DR, Hurel SJ, Miller GJ, Cooper JA, Humphries SE. Increased plasma markers of oxidative stress are associated with coronary heart disease in males with diabetes mellitus and with 10-year risk in a prospective sample of males. Clin Chem 2006; 52: 446-452.
    • (2006) Clin Chem , vol.52 , pp. 446-452
    • Stephens, J.W.1    Gable, D.R.2    Hurel, S.J.3    Miller, G.J.4    Cooper, J.A.5    Humphries, S.E.6
  • 112
    • 33747872585 scopus 로고    scopus 로고
    • Is plasma oxidized low-density lipoprotein, measured with the widely used antibody 4E6, an independent predictor of coronary heart disease among U.S. men and women?
    • Wu T, Willett WC, Rifai N, Shai I, Manson JE, Rimm EB. Is plasma oxidized low-density lipoprotein, measured with the widely used antibody 4E6, an independent predictor of coronary heart disease among U.S. men and women? J Am Coll Cardiol 2006; 48: 973-979.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 973-979
    • Wu, T.1    Willett, W.C.2    Rifai, N.3    Shai, I.4    Manson, J.E.5    Rimm, E.B.6
  • 113
    • 10744230298 scopus 로고    scopus 로고
    • Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: A matched case-control study
    • Schwedhelm E, Bartling A, Lenzen H, et al. Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study. Circulation 2004; 109: 843-848.
    • (2004) Circulation , vol.109 , pp. 843-848
    • Schwedhelm, E.1    Bartling, A.2    Lenzen, H.3
  • 114
    • 30044434546 scopus 로고    scopus 로고
    • Associations of plasma 8-isoprostane levels with the presence and extent of coronary stenosis in patients with coronary artery disease
    • Wang B, Pan J, Wang L, Zhu H, Yu R, Zou Y. Associations of plasma 8-isoprostane levels with the presence and extent of coronary stenosis in patients with coronary artery disease. Atherosclerosis 2006; 184: 425-430.
    • (2006) Atherosclerosis , vol.184 , pp. 425-430
    • Wang, B.1    Pan, J.2    Wang, L.3    Zhu, H.4    Yu, R.5    Zou, Y.6
  • 115
    • 3042748693 scopus 로고    scopus 로고
    • Established and emerging plasma biomarkers in the prediction of first atherothrombotic events
    • Ridker PM, Brown NJ, Vaughan DE, Harrison DG, Mehta JL, Established and emerging plasma biomarkers in the prediction of first atherothrombotic events. Circulation 2004; 109: IV6-19.
    • (2004) Circulation , vol.109
    • Ridker, P.M.1    Brown, N.J.2    Vaughan, D.E.3    Harrison, D.G.4    Mehta, J.L.5
  • 116
    • 0142057430 scopus 로고    scopus 로고
    • Glutathione peroxidase I activity and cardiovascular events in patients with coronary artery disease
    • Blankenberg S, Rupprecht HJ, Bickel C, et al. Glutathione peroxidase I activity and cardiovascular events in patients with coronary artery disease. N Engl J Med 2003; 349: 1605-1613.
    • (2003) N Engl J Med , vol.349 , pp. 1605-1613
    • Blankenberg, S.1    Rupprecht, H.J.2    Bickel, C.3
  • 117
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 1999; 354: 447-455.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 118
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 154-160.
    • (2000) N Engl J Med , vol.342 , pp. 154-160
    • Yusuf, S.1    Dagenais, G.2    Pogue, J.3    Bosch, J.4    Sleight, P.5
  • 119
    • 0035852471 scopus 로고    scopus 로고
    • Low-dose aspirin and vitamin E in people at cardiovascular risk: A randomised trial in general practice. Collaborative Group of the Primary Prevention Project
    • de Gaetano G. Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Collaborative Group of the Primary Prevention Project. Lancet 2001; 357: 89-95.
    • (2001) Lancet , vol.357 , pp. 89-95
    • de Gaetano, G.1
  • 120
    • 0035489789 scopus 로고    scopus 로고
    • Bioavailability of vitamin E as function of food intake in healthy subjects: Effects on plasma peroxide-scavenging activity and cholesterol-oxidation products
    • Iuliano L, Micheletta F, Maranghi M, Frati G, Diczfalusy U, Violi F. Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. Arterioscler Thromb Vasc Biol 2001; 21: E34-37.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21
    • Iuliano, L.1    Micheletta, F.2    Maranghi, M.3    Frati, G.4    Diczfalusy, U.5    Violi, F.6
  • 121
    • 0038164595 scopus 로고    scopus 로고
    • Timing of antioxidant vitamin ingestion alters postprandial proatherogenic serum markers
    • Carroll MF, Schade DS. Timing of antioxidant vitamin ingestion alters postprandial proatherogenic serum markers. Circulation 2003; 108: 24-31.
    • (2003) Circulation , vol.108 , pp. 24-31
    • Carroll, M.F.1    Schade, D.S.2
  • 122
    • 0030916162 scopus 로고    scopus 로고
    • Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction
    • Rapola JM, Virtamo J, Ripatti S, et al. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 1997; 349: 1715-1720.
    • (1997) Lancet , vol.349 , pp. 1715-1720
    • Rapola, J.M.1    Virtamo, J.2    Ripatti, S.3
  • 123
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
    • Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996; 347: 781-786.
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6
  • 124
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with anti-oxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial
    • Boaz M, Smetana S, Weinstein T, et al. Secondary prevention with anti-oxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000; 356: 1213-1218.
    • (2000) Lancet , vol.356 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3
  • 125
    • 0037031094 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360: 23-33.
    • MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360: 23-33.
  • 126
    • 0037197039 scopus 로고    scopus 로고
    • Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: A randomised trial
    • Fang JC, Kinlay S, Beltrame J, et al. Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial. Lancet 2002; 359: 1108-1113.
    • (2002) Lancet , vol.359 , pp. 1108-1113
    • Fang, J.C.1    Kinlay, S.2    Beltrame, J.3
  • 127
    • 0037465430 scopus 로고    scopus 로고
    • Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: The Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study
    • Salonen RM, Nyyssonen K, Kaikkonen J, et al. Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: the Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study. Circulation 2003; 107: 947-953.
    • (2003) Circulation , vol.107 , pp. 947-953
    • Salonen, R.M.1    Nyyssonen, K.2    Kaikkonen, J.3
  • 128
    • 0033983165 scopus 로고    scopus 로고
    • Vitamin E and heart disease: Basic science to clinical intervention trials
    • Pryor WA. Vitamin E and heart disease: basic science to clinical intervention trials. Free Radic Biol Med 2000; 28: 141-164.
    • (2000) Free Radic Biol Med , vol.28 , pp. 141-164
    • Pryor, W.A.1
  • 129
    • 0037840165 scopus 로고    scopus 로고
    • Use of antioxidant vitamins for the prevention of cardiovascular disease: Meta-analysis of randomised trials
    • Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 2003; 361: 2017-2023.
    • (2003) Lancet , vol.361 , pp. 2017-2023
    • Vivekananthan, D.P.1    Penn, M.S.2    Sapp, S.K.3    Hsu, A.4    Topol, E.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.