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Volumn 130, Issue 1, 2007, Pages 25-35

Multistep Pathogenesis of Autoimmune Disease

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; BIM PROTEIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 7 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN A1; PROTEIN BCL 2; PROTEIN BCL XL; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

EID: 34447098797     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2007.06.033     Document Type: Review
Times cited : (351)

References (101)
  • 3
    • 0033609114 scopus 로고    scopus 로고
    • Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals
    • Araten D.J., Nafa K., Pakdeesuwan K., and Luzzatto L. Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals. Proc. Natl. Acad. Sci. USA 96 (1999) 5209-5214
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5209-5214
    • Araten, D.J.1    Nafa, K.2    Pakdeesuwan, K.3    Luzzatto, L.4
  • 4
    • 18244385722 scopus 로고    scopus 로고
    • Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
    • Bende R.J., Aarts W.M., Riedl R.G., de Jong D., Pals S.T., and van Noesel C.J. Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity. J. Exp. Med. 201 (2005) 1229-1241
    • (2005) J. Exp. Med. , vol.201 , pp. 1229-1241
    • Bende, R.J.1    Aarts, W.M.2    Riedl, R.G.3    de Jong, D.4    Pals, S.T.5    van Noesel, C.J.6
  • 8
    • 64549115221 scopus 로고    scopus 로고
    • Clinical review 93: Autoimmune polyglandular syndrome type 1
    • Betterle C., Greggio N.A., and Volpato M. Clinical review 93: Autoimmune polyglandular syndrome type 1. J. Clin. Endocrinol. Metab. 83 (1998) 1049-1055
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 1049-1055
    • Betterle, C.1    Greggio, N.A.2    Volpato, M.3
  • 9
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature 430 (2004) 257-263
    • (2004) Nature , vol.430 , pp. 257-263
    • Beutler, B.1
  • 11
    • 0014941813 scopus 로고
    • A theory of self-nonself discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively
    • Bretscher P., and Cohn M. A theory of self-nonself discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively. Science 169 (1970) 1042-1049
    • (1970) Science , vol.169 , pp. 1042-1049
    • Bretscher, P.1    Cohn, M.2
  • 13
    • 33749132566 scopus 로고    scopus 로고
    • Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN
    • Buckler J.L., Walsh P.T., Porrett P.M., Choi Y., and Turka L.A. Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN. J. Immunol. 177 (2006) 4262-4266
    • (2006) J. Immunol. , vol.177 , pp. 4262-4266
    • Buckler, J.L.1    Walsh, P.T.2    Porrett, P.M.3    Choi, Y.4    Turka, L.A.5
  • 18
    • 0032769336 scopus 로고    scopus 로고
    • The central and multiple roles of B cells in lupus pathogenesis
    • Chan O.T., Madaio M.P., and Shlomchik M.J. The central and multiple roles of B cells in lupus pathogenesis. Immunol. Rev. 169 (1999) 107-121
    • (1999) Immunol. Rev. , vol.169 , pp. 107-121
    • Chan, O.T.1    Madaio, M.P.2    Shlomchik, M.J.3
  • 19
    • 0029661825 scopus 로고    scopus 로고
    • VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection
    • Chapman C.J., Zhou J.X., Gregory C., Rickinson A.B., and Stevenson F.K. VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection. Blood 88 (1996) 3562-3568
    • (1996) Blood , vol.88 , pp. 3562-3568
    • Chapman, C.J.1    Zhou, J.X.2    Gregory, C.3    Rickinson, A.B.4    Stevenson, F.K.5
  • 20
    • 33646029133 scopus 로고    scopus 로고
    • Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mice
    • Chen C., Li H., Tian Q., Beardall M., Xu Y., Casanova N., and Weigert M. Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mice. J. Immunol. 176 (2006) 5183-5190
    • (2006) J. Immunol. , vol.176 , pp. 5183-5190
    • Chen, C.1    Li, H.2    Tian, Q.3    Beardall, M.4    Xu, Y.5    Casanova, N.6    Weigert, M.7
  • 21
    • 0025875259 scopus 로고
    • Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen P.L., and Eisenberg R.A. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9 (1991) 243-269
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 22
    • 0035284866 scopus 로고    scopus 로고
    • Expression of a V region-less B cell receptor confers a tolerance-like phenotype on transgenic B cells
    • Corcos D., Grandien A., Vazquez A., Dunda O., Lores P., and Bucchini D. Expression of a V region-less B cell receptor confers a tolerance-like phenotype on transgenic B cells. J. Immunol. 166 (2001) 3083-3089
    • (2001) J. Immunol. , vol.166 , pp. 3083-3089
    • Corcos, D.1    Grandien, A.2    Vazquez, A.3    Dunda, O.4    Lores, P.5    Bucchini, D.6
  • 24
    • 1542283724 scopus 로고    scopus 로고
    • VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia
    • Egle A., Harris A.W., Bath M.L., O'Reilly L., and Cory S. VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia. Blood 103 (2004) 2276-2283
    • (2004) Blood , vol.103 , pp. 2276-2283
    • Egle, A.1    Harris, A.W.2    Bath, M.L.3    O'Reilly, L.4    Cory, S.5
  • 26
    • 0037342752 scopus 로고    scopus 로고
    • Somatic gene mutation and human disease other than cancer
    • Erickson R.P. Somatic gene mutation and human disease other than cancer. Mutat. Res. 543 (2003) 125-136
    • (2003) Mutat. Res. , vol.543 , pp. 125-136
    • Erickson, R.P.1
  • 27
    • 34447099218 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease
    • Fairhurst A.M., Wandstrat A.E., and Wakeland E.K. Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease. Adv. Immunol. 92 (2006) 1-69
    • (2006) Adv. Immunol. , vol.92 , pp. 1-69
    • Fairhurst, A.M.1    Wandstrat, A.E.2    Wakeland, E.K.3
  • 29
    • 0034097043 scopus 로고    scopus 로고
    • Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex
    • Fearon D.T., and Carroll M.C. Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Annu. Rev. Immunol. 18 (2000) 393-422
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 393-422
    • Fearon, D.T.1    Carroll, M.C.2
  • 32
    • 0034628560 scopus 로고    scopus 로고
    • How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis
    • Glynne R., Akkaraju S., Healy J.I., Rayner J., Goodnow C.C., and Mack D.H. How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis. Nature 403 (2000) 672-676
    • (2000) Nature , vol.403 , pp. 672-676
    • Glynne, R.1    Akkaraju, S.2    Healy, J.I.3    Rayner, J.4    Goodnow, C.C.5    Mack, D.H.6
  • 33
    • 33745155733 scopus 로고    scopus 로고
    • Immunology. Discriminating microbe from self suffers a double toll
    • Goodnow C.C. Immunology. Discriminating microbe from self suffers a double toll. Science 312 (2006) 1606-1608
    • (2006) Science , vol.312 , pp. 1606-1608
    • Goodnow, C.C.1
  • 34
    • 20444485767 scopus 로고    scopus 로고
    • Cellular and genetic mechanisms of self tolerance and autoimmunity
    • Goodnow C.C., Sprent J., de St Groth B.F., and Vinuesa C.G. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature 435 (2005) 590-597
    • (2005) Nature , vol.435 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2    de St Groth, B.F.3    Vinuesa, C.G.4
  • 38
    • 0036928333 scopus 로고    scopus 로고
    • B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent induction of Rel/NF-kappaB regulated c-myc transcription
    • Grumont R.J., Strasser A., and Gerondakis S. B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent induction of Rel/NF-kappaB regulated c-myc transcription. Mol. Cell 10 (2002) 1283-1294
    • (2002) Mol. Cell , vol.10 , pp. 1283-1294
    • Grumont, R.J.1    Strasser, A.2    Gerondakis, S.3
  • 42
    • 0030045265 scopus 로고    scopus 로고
    • Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue
    • Hussell T., Isaacson P.G., Crabtree J.E., and Spencer J. Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue. J. Pathol. 178 (1996) 122-127
    • (1996) J. Pathol. , vol.178 , pp. 122-127
    • Hussell, T.1    Isaacson, P.G.2    Crabtree, J.E.3    Spencer, J.4
  • 43
    • 0030058657 scopus 로고    scopus 로고
    • The repertoire of T cells shaped by a single MHC/peptide ligand
    • Ignatowicz L., Kappler J., and Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 84 (1996) 521-529
    • (1996) Cell , vol.84 , pp. 521-529
    • Ignatowicz, L.1    Kappler, J.2    Marrack, P.3
  • 44
    • 0028326095 scopus 로고
    • Prevention of nephritis in major histocompatibility complex Class II-deficient MRL-lpr mice
    • Jevnikar A.M., Grusby M.J., and Glimcher L.H. Prevention of nephritis in major histocompatibility complex Class II-deficient MRL-lpr mice. J. Exp. Med. 179 (1994) 1137-1143
    • (1994) J. Exp. Med. , vol.179 , pp. 1137-1143
    • Jevnikar, A.M.1    Grusby, M.J.2    Glimcher, L.H.3
  • 45
    • 25144432460 scopus 로고    scopus 로고
    • Modifier loci condition autoimmunity provoked by Aire deficiency
    • Jiang W., Anderson M.S., Bronson R., Mathis D., and Benoist C. Modifier loci condition autoimmunity provoked by Aire deficiency. J. Exp. Med. 202 (2005) 805-815
    • (2005) J. Exp. Med. , vol.202 , pp. 805-815
    • Jiang, W.1    Anderson, M.S.2    Bronson, R.3    Mathis, D.4    Benoist, C.5
  • 47
    • 0036679733 scopus 로고    scopus 로고
    • It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation
    • Kane L.P., Lin J., and Weiss A. It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. Trends Immunol. 23 (2002) 413-420
    • (2002) Trends Immunol. , vol.23 , pp. 413-420
    • Kane, L.P.1    Lin, J.2    Weiss, A.3
  • 48
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim J.M., Rasmussen J.P., and Rudensky A.Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8 (2007) 191-197
    • (2007) Nat. Immunol. , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 50
    • 29644436116 scopus 로고    scopus 로고
    • A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice
    • Komori H., Furukawa H., Mori S., Ito M.R., Terada M., Zhang M.C., Ishii N., Sakuma N., Nose M., and Ono M. A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice. J. Immunol. 176 (2006) 395-400
    • (2006) J. Immunol. , vol.176 , pp. 395-400
    • Komori, H.1    Furukawa, H.2    Mori, S.3    Ito, M.R.4    Terada, M.5    Zhang, M.C.6    Ishii, N.7    Sakuma, N.8    Nose, M.9    Ono, M.10
  • 51
    • 9644295710 scopus 로고    scopus 로고
    • Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
    • Kovanen P.E., and Leonard W.J. Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol. Rev. 202 (2004) 67-83
    • (2004) Immunol. Rev. , vol.202 , pp. 67-83
    • Kovanen, P.E.1    Leonard, W.J.2
  • 52
    • 0033491193 scopus 로고    scopus 로고
    • CD95(APO-1/Fas)-mediated apoptosis: live and let die
    • Krammer P.H. CD95(APO-1/Fas)-mediated apoptosis: live and let die. Adv. Immunol. 71 (1999) 163-210
    • (1999) Adv. Immunol. , vol.71 , pp. 163-210
    • Krammer, P.H.1
  • 53
    • 0020977018 scopus 로고
    • Immunobiology of tissue transplantation: a return to the passenger leukocyte concept
    • Lafferty K.J., Prowse S.J., Simeoniovic C.J., and Warren H.S. Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. Annu. Rev. Immunol. 1 (1983) 143-173
    • (1983) Annu. Rev. Immunol. , vol.1 , pp. 143-173
    • Lafferty, K.J.1    Prowse, S.J.2    Simeoniovic, C.J.3    Warren, H.S.4
  • 54
    • 33748448717 scopus 로고    scopus 로고
    • Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms
    • Li M.O., Sanjabi S., and Flavell R.A. Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity 25 (2006) 455-471
    • (2006) Immunity , vol.25 , pp. 455-471
    • Li, M.O.1    Sanjabi, S.2    Flavell, R.A.3
  • 57
    • 16244418695 scopus 로고    scopus 로고
    • Genetic lesions in T-cell tolerance and thresholds for autoimmunity
    • Liston A., Lesage S., Gray D.H., Boyd R.L., and Goodnow C.C. Genetic lesions in T-cell tolerance and thresholds for autoimmunity. Immunol. Rev. 204 (2005) 87-101
    • (2005) Immunol. Rev. , vol.204 , pp. 87-101
    • Liston, A.1    Lesage, S.2    Gray, D.H.3    Boyd, R.L.4    Goodnow, C.C.5
  • 58
    • 0029939451 scopus 로고    scopus 로고
    • Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses
    • Ma J., Xu J., Madaio M.P., Peng Q., Zhang J., Grewal I.S., Flavell R.A., and Craft J. Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses. J. Immunol. 157 (1996) 417-426
    • (1996) J. Immunol. , vol.157 , pp. 417-426
    • Ma, J.1    Xu, J.2    Madaio, M.P.3    Peng, Q.4    Zhang, J.5    Grewal, I.S.6    Flavell, R.A.7    Craft, J.8
  • 60
    • 33748465396 scopus 로고    scopus 로고
    • Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor
    • Marie J.C., Liggitt D., and Rudensky A.Y. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25 (2006) 441-454
    • (2006) Immunity , vol.25 , pp. 441-454
    • Marie, J.C.1    Liggitt, D.2    Rudensky, A.Y.3
  • 62
    • 33750369226 scopus 로고    scopus 로고
    • Toll-like receptors in systemic autoimmune disease
    • Marshak-Rothstein A. Toll-like receptors in systemic autoimmune disease. Nat. Rev. Immunol. 6 (2006) 823-835
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 823-835
    • Marshak-Rothstein, A.1
  • 63
    • 0024816443 scopus 로고
    • Differential effect of the autoimmune Yaa and lpr genes on the acceleration of lupus-like syndrome in MRL/MpJ mice
    • Merino R., Shibata T., De Kossodo S., and Izui S. Differential effect of the autoimmune Yaa and lpr genes on the acceleration of lupus-like syndrome in MRL/MpJ mice. Eur. J. Immunol. 19 (1989) 2131-2137
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2131-2137
    • Merino, R.1    Shibata, T.2    De Kossodo, S.3    Izui, S.4
  • 64
    • 0034684682 scopus 로고    scopus 로고
    • Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction
    • Muschen M., Re D., Jungnickel B., Diehl V., Rajewsky K., and Kuppers R. Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction. J. Exp. Med. 192 (2000) 1833-1840
    • (2000) J. Exp. Med. , vol.192 , pp. 1833-1840
    • Muschen, M.1    Re, D.2    Jungnickel, B.3    Diehl, V.4    Rajewsky, K.5    Kuppers, R.6
  • 65
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S., and Golstein P. The Fas death factor. Science 267 (1995) 1449-1456
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 66
    • 33644772836 scopus 로고    scopus 로고
    • CARMA1 is required for Akt-mediated NF-kappaB activation in T cells
    • Narayan P., Holt B., Tosti R., and Kane L.P. CARMA1 is required for Akt-mediated NF-kappaB activation in T cells. Mol. Cell. Biol. 26 (2006) 2327-2336
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2327-2336
    • Narayan, P.1    Holt, B.2    Tosti, R.3    Kane, L.P.4
  • 68
    • 0034969437 scopus 로고    scopus 로고
    • Are rare variants responsible for susceptibility to complex diseases?
    • Pritchard J.K. Are rare variants responsible for susceptibility to complex diseases?. Am. J. Hum. Genet. 69 (2001) 124-137
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 124-137
    • Pritchard, J.K.1
  • 69
    • 0028129894 scopus 로고
    • Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
    • Rathmell J.C., and Goodnow C.C. Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J. Immunol. 153 (1994) 2831-2842
    • (1994) J. Immunol. , vol.153 , pp. 2831-2842
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 72
    • 0035871845 scopus 로고    scopus 로고
    • Anti-Sm B cell differentiation in Ig transgenic MRL/Mp-lpr/lpr mice: altered differentiation and an accelerated response
    • Santulli-Marotto S., Qian Y., Ferguson S., and Clarke S.H. Anti-Sm B cell differentiation in Ig transgenic MRL/Mp-lpr/lpr mice: altered differentiation and an accelerated response. J. Immunol. 166 (2001) 5292-5299
    • (2001) J. Immunol. , vol.166 , pp. 5292-5299
    • Santulli-Marotto, S.1    Qian, Y.2    Ferguson, S.3    Clarke, S.H.4
  • 73
    • 0035995044 scopus 로고    scopus 로고
    • Inhibition of Fas-mediated apoptosis by antigen: implications for lymphomagenesis
    • Schattner E.J., Friedman S.M., and Casali P. Inhibition of Fas-mediated apoptosis by antigen: implications for lymphomagenesis. Autoimmunity 35 (2002) 283-289
    • (2002) Autoimmunity , vol.35 , pp. 283-289
    • Schattner, E.J.1    Friedman, S.M.2    Casali, P.3
  • 78
    • 33750517284 scopus 로고    scopus 로고
    • Autoimmune diseases, asthma and risk of haematological malignancies: a nationwide case-control study in Sweden
    • Soderberg K.C., Jonsson F., Winqvist O., Hagmar L., and Feychting M. Autoimmune diseases, asthma and risk of haematological malignancies: a nationwide case-control study in Sweden. Eur. J. Cancer 42 (2006) 3028-3033
    • (2006) Eur. J. Cancer , vol.42 , pp. 3028-3033
    • Soderberg, K.C.1    Jonsson, F.2    Winqvist, O.3    Hagmar, L.4    Feychting, M.5
  • 79
    • 14944348965 scopus 로고    scopus 로고
    • The role of BH3-only proteins in the immune system
    • Strasser A. The role of BH3-only proteins in the immune system. Nat. Rev. Immunol. 5 (2005) 189-200
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 189-200
    • Strasser, A.1
  • 80
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser A., Harris A.W., Huang D.C., Krammer P.H., and Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14 (1995) 6136-6147
    • (1995) EMBO J. , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krammer, P.H.4    Cory, S.5
  • 81
    • 0035412359 scopus 로고    scopus 로고
    • The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis
    • Straus S.E., Jaffe E.S., Puck J.M., Dale J.K., Elkon K.B., Rosen-Wolff A., Peters A.M., Sneller M.C., Hallahan C.W., Wang J., et al. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood 98 (2001) 194-200
    • (2001) Blood , vol.98 , pp. 194-200
    • Straus, S.E.1    Jaffe, E.S.2    Puck, J.M.3    Dale, J.K.4    Elkon, K.B.5    Rosen-Wolff, A.6    Peters, A.M.7    Sneller, M.C.8    Hallahan, C.W.9    Wang, J.10
  • 82
    • 33645051417 scopus 로고    scopus 로고
    • Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation
    • Suarez F., Lortholary O., Hermine O., and Lecuit M. Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation. Blood 107 (2006) 3034-3044
    • (2006) Blood , vol.107 , pp. 3034-3044
    • Suarez, F.1    Lortholary, O.2    Hermine, O.3    Lecuit, M.4
  • 86
    • 0028945022 scopus 로고
    • Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice
    • Tighe H., Heaphy P., Baird S., Weigle W.O., and Carson D.A. Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice. J. Exp. Med. 181 (1995) 599-606
    • (1995) J. Exp. Med. , vol.181 , pp. 599-606
    • Tighe, H.1    Heaphy, P.2    Baird, S.3    Weigle, W.O.4    Carson, D.A.5
  • 87
    • 0023252262 scopus 로고
    • HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
    • Todd J.A., Bell J.I., and McDevitt H.O. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329 (1987) 599-604
    • (1987) Nature , vol.329 , pp. 599-604
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 89
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse T.J., and Todd J.A. Genetic analysis of autoimmune disease. Cell 85 (1996) 311-318
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 90
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan Y.Y., and Flavell R.A. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 445 (2007) 766-770
    • (2007) Nature , vol.445 , pp. 766-770
    • Wan, Y.Y.1    Flavell, R.A.2
  • 92
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • Williams L.M., and Rudensky A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol. 8 (2007) 277-284
    • (2007) Nat. Immunol. , vol.8 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 93
    • 0032745697 scopus 로고    scopus 로고
    • Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros
    • Winandy S., Wu L., Wang J.H., and Georgopoulos K. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. J. Exp. Med. 190 (1999) 1039-1048
    • (1999) J. Exp. Med. , vol.190 , pp. 1039-1048
    • Winandy, S.1    Wu, L.2    Wang, J.H.3    Georgopoulos, K.4
  • 94
    • 0035927093 scopus 로고    scopus 로고
    • Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands
    • Wong P., Barton G.M., Forbush K.A., and Rudensky A.Y. Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands. J. Exp. Med. 193 (2001) 1179-1187
    • (2001) J. Exp. Med. , vol.193 , pp. 1179-1187
    • Wong, P.1    Barton, G.M.2    Forbush, K.A.3    Rudensky, A.Y.4
  • 95
    • 0032707163 scopus 로고    scopus 로고
    • Population choice in mapping genes for complex diseases
    • Wright A.F., Carothers A.D., and Pirastu M. Population choice in mapping genes for complex diseases. Nat. Genet. 23 (1999) 397-404
    • (1999) Nat. Genet. , vol.23 , pp. 397-404
    • Wright, A.F.1    Carothers, A.D.2    Pirastu, M.3
  • 98
    • 0030935007 scopus 로고    scopus 로고
    • The MHC reactivity of the T cell repertoire prior to positive and negative selection
    • Zerrahn J., Held W., and Raulet D.H. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell 88 (1997) 627-636
    • (1997) Cell , vol.88 , pp. 627-636
    • Zerrahn, J.1    Held, W.2    Raulet, D.H.3
  • 100
    • 33847220736 scopus 로고    scopus 로고
    • Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
    • Zheng Y., Josefowicz S.Z., Kas A., Chu T.T., Gavin M.A., and Rudensky A.Y. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 445 (2007) 936-940
    • (2007) Nature , vol.445 , pp. 936-940
    • Zheng, Y.1    Josefowicz, S.Z.2    Kas, A.3    Chu, T.T.4    Gavin, M.A.5    Rudensky, A.Y.6
  • 101
    • 27844511909 scopus 로고    scopus 로고
    • The risk of lymphoma development in autoimmune diseases: a meta-analysis
    • Zintzaras E., Voulgarelis M., and Moutsopoulos H.M. The risk of lymphoma development in autoimmune diseases: a meta-analysis. Arch. Intern. Med. 165 (2005) 2337-2344
    • (2005) Arch. Intern. Med. , vol.165 , pp. 2337-2344
    • Zintzaras, E.1    Voulgarelis, M.2    Moutsopoulos, H.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.