메뉴 건너뛰기




Volumn 23, Issue 8, 2002, Pages 413-420

It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR;

EID: 0036679733     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4906(02)02264-0     Document Type: Review
Times cited : (166)

References (81)
  • 5
    • 0027451433 scopus 로고
    • B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance
    • (1993) J. Exp. Med. , vol.178 , pp. 1753-1763
    • Boussiotis, V.A.1
  • 6
    • 0030701952 scopus 로고    scopus 로고
    • Distinct roles for LFA-1 and CD28 during activation of naïve T cells: Adhesion versus costimulation
    • (1997) Immunity , vol.7 , pp. 549-557
    • Bachmann, M.F.1
  • 9
    • 0022458229 scopus 로고
    • Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells
    • (1986) J. Immunol. , vol.137 , pp. 819-825
    • Weiss, A.1
  • 13
    • 0024584166 scopus 로고
    • Kappa B-specific DNA binding proteins: Role in the regulation of human interleukin-2 gene expression
    • (1989) Science , vol.244 , pp. 457-460
    • Hoyos, B.1
  • 14
    • 0024751072 scopus 로고
    • Activation of the interleukin-2 receptor alpha gene: Regulatory role for DNA-protein interactions flanking the kappa B enhancer
    • (1989) New Biol. , vol.1 , pp. 83-92
    • Ballard, D.W.1
  • 15
    • 0024848203 scopus 로고
    • A second sequence element located 3′ to the NF-κB-binding site regulates IL-2 receptor-alpha gene induction
    • (1989) J. Immunol. , vol.143 , pp. 4275-4281
    • Pomerantz, J.L.1
  • 16
    • 0025915550 scopus 로고
    • Physiologic activation of T cells via the T cell receptor induces NF-κB
    • (1991) J. Immunol. , vol.147 , pp. 416-420
    • Jamieson, C.1
  • 17
    • 0026764920 scopus 로고
    • NF-κB subunit regulation in nontransformed CD4+ T lymphocytes
    • (1992) Science , vol.256 , pp. 1452-1456
    • Kang, S.M.1
  • 18
    • 0026061865 scopus 로고
    • Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
    • (1991) Science , vol.251 , pp. 313-316
    • Fraser, J.D.1
  • 20
    • 0026332710 scopus 로고
    • Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element
    • (1991) J. Biol. Chem. , vol.266 , pp. 14179-14182
    • Verweij, C.L.1
  • 21
    • 0026607074 scopus 로고
    • CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation
    • (1992) J. Exp. Med. , vol.175 , pp. 1131-1134
    • Fraser, J.D.1
  • 22
    • 0031001510 scopus 로고    scopus 로고
    • CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4051-4058
    • Shapiro, V.S.1
  • 23
    • 0029000938 scopus 로고
    • RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4260-4271
    • Lai, J.-H.1
  • 24
    • 0030294284 scopus 로고    scopus 로고
    • High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters
    • (1996) Immunity , vol.5 , pp. 479-489
    • Himes, S.R.1
  • 25
    • 0030958177 scopus 로고    scopus 로고
    • Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-κB/Rel transcription factors
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2605-2614
    • Maggirwar, S.B.1
  • 26
    • 0031204429 scopus 로고    scopus 로고
    • Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 element/AP-1 sequence in human T cells
    • (1997) J. Immunol. , vol.159 , pp. 1319-1327
    • McGuire, K.L.1    Iacobelli, M.2
  • 28
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • (1995) Genes Dev. , vol.9 , pp. 1965-1977
    • Kontgen, F.1
  • 29
    • 0037090259 scopus 로고    scopus 로고
    • Molecular mechanisms underlying differential contribution of CD28 versus non-CD28 costimulatory molecules to IL-2 promoter activation
    • (2002) J. Immunol. , vol.168 , pp. 3847-3854
    • Zhou, X.Y.1
  • 30
    • 0033607804 scopus 로고    scopus 로고
    • Functional disparity of distinct CD28 response elements toward mitogenic responses
    • (1999) J. Biol. Chem. , vol.274 , pp. 34369-34374
    • Civil, A.1
  • 31
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1
  • 32
    • 0033621956 scopus 로고    scopus 로고
    • The Rel/NF-κB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2687-2695
    • Chen, C.1
  • 33
    • 0034663779 scopus 로고    scopus 로고
    • The NF-κB cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes
    • (2000) J. Immunol. , vol.165 , pp. 1743-1754
    • Khoshnan, A.1
  • 34
    • 0032534281 scopus 로고    scopus 로고
    • Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: Requirement for CD28 up-regulation of RE/AP
    • (1998) J. Immunol. , vol.161 , pp. 6455-6458
    • Shapiro, V.S.1
  • 35
    • 0034653531 scopus 로고    scopus 로고
    • The role of high-mobility group I(Y) proteins in expression of IL-2 and T cell proliferation
    • (2000) J. Immunol. , vol.164 , pp. 3157-3168
    • Himes, S.R.1
  • 37
    • 0028019261 scopus 로고
    • Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7933-7942
    • Bryan, R.G.1
  • 38
    • 0030851835 scopus 로고    scopus 로고
    • Temporal and subunit-specific modulations of the Rel/NF-κB transcription factors through CD28 costimulation
    • (1997) J. Biol. Chem. , vol.272 , pp. 21774-21783
    • Kahn-Perles, B.1
  • 39
    • 0030209806 scopus 로고    scopus 로고
    • Differential regulation of c-Rel translocation in activated B and T cells
    • (1996) J. Immunol. , vol.157 , pp. 1149-1155
    • Venkataraman, L.1
  • 40
    • 0030907779 scopus 로고    scopus 로고
    • C-Rel is a target of pentoxifylline-mediated inhibition of T lymphocyte activation
    • (1997) Immunity , vol.6 , pp. 165-174
    • Wang, W.1
  • 41
    • 0029977948 scopus 로고    scopus 로고
    • CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6736-6743
    • Harhaj, E.W.1
  • 42
    • 0027970168 scopus 로고
    • CD28 signaling causes a sustained down-regulation of IκBα which can be prevented by the immunosuppressant rapamycin
    • (1994) J. Biol. Chem. , vol.269 , pp. 30077-30080
    • Lai, J.-H.1    Tan, T.-H.2
  • 43
    • 0030899121 scopus 로고    scopus 로고
    • I kappa B epsilon, a novel member of the IκB family, controls RelA and cRel NF-κB activity
    • (1997) EMBO J. , vol.16 , pp. 1413-1426
    • Whiteside, S.T.1
  • 44
    • 0033596123 scopus 로고    scopus 로고
    • Genetic approaches in mice to understand Rel/NF-κB and IκB function: Transgenics and knockouts
    • (1999) Oncogene , vol.18 , pp. 6888-6895
    • Gerondakis, S.1
  • 46
    • 0033571070 scopus 로고    scopus 로고
    • Primary human CD4+ T cells contain heterogeneous IκB kinase complexes: Role in activation of the IL-2 promoter
    • (1999) J. Immunol. , vol.163 , pp. 5444-5452
    • Khoshnan, A.1
  • 47
    • 0033829852 scopus 로고    scopus 로고
    • Mitogen-activated kinase kinase kinase 1 regulates T cell receptor-and CD28-mediated signaling events which lead to NF-κB activation
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2445-2454
    • Tuosto, L.1
  • 48
    • 0034624810 scopus 로고    scopus 로고
    • Somatic mutagenesis studies of NF-κB signaling in human T cells: Evidence for an essential role of IKK γ in NF-κB activation by T-cell costimulatory signals and HTLV-I Tax protein
    • (2000) Oncogene , vol.19 , pp. 1448-1456
    • Harhaj, E.W.1
  • 50
    • 0032808084 scopus 로고    scopus 로고
    • IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases
    • (1999) Int. Immunol. , vol.11 , pp. 1357-1362
    • Shimada, T.1
  • 53
    • 0035339837 scopus 로고    scopus 로고
    • ZAP-70 and SLP-76 regulate protein kinase C-? and NF-κB activation in response to engagement of CD3 and CD28
    • (2001) J. Immunol. , vol.166 , pp. 5654-5664
    • Herndon, T.M.1
  • 55
    • 0034288906 scopus 로고    scopus 로고
    • A novel functional interaction between Vav and PKC? is required for TCR-induced T cell activation
    • (2000) Immunity , vol.12 , pp. 151-160
    • Villalba, M.1
  • 56
    • 0037029653 scopus 로고    scopus 로고
    • Vav1 transduces T cell receptor signals to the activation of phospholipase Cγ1 via phosphoinositide 3-kinase-dependent and -independent pathways
    • (2002) J. Exp. Med. , vol.195 , pp. 1103-1114
    • Reynolds, L.F.1
  • 57
    • 0034073381 scopus 로고    scopus 로고
    • Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IκB kinase complex
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2556-2568
    • Hehner, S.P.1
  • 58
    • 0033082990 scopus 로고    scopus 로고
    • The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-κB acting through the NF-κB-inducing kinase and IκB kinases
    • (1999) Immunity , vol.10 , pp. 271-280
    • Lin, X.1
  • 61
    • 17744371331 scopus 로고    scopus 로고
    • TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
    • (2000) Cell , vol.103 , pp. 1071-1083
    • Dumitru, C.D.1
  • 62
    • 0034662002 scopus 로고    scopus 로고
    • Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-κB-inducing kinase
    • (2000) J. Immunol. , vol.165 , pp. 804-812
    • Yamada, T.1
  • 64
    • 0035221568 scopus 로고    scopus 로고
    • Akt provides the CD28 co-stimulatory signal for upregulation of IL-2 and IFN-γ but not Th2 cytokines
    • (2001) Nat. Immun. , vol.2 , pp. 37-44
    • Kane, L.P.1
  • 65
    • 0035943657 scopus 로고    scopus 로고
    • Complex formation and cooperation of protein kinase C θ and Akt1/protein kinase Bα in the NF-κB transactivation cascade in Jurkat T cells
    • (2001) J. Biol. Chem. , vol.276 , pp. 31627-31634
    • Bauer, B.1
  • 67
    • 0034031401 scopus 로고    scopus 로고
    • Protein kinase C-θ participates in NF-κB activation induced by CD3-CD28 costimulation through selective activation of IκB kinase β
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2933-2940
    • Lin, X.1
  • 68
    • 0036316344 scopus 로고    scopus 로고
    • Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription
    • in press
    • Mol. Cell. Biol.
    • Kane, L.P.1
  • 69
    • 18844473151 scopus 로고    scopus 로고
    • PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
    • (2000) Nature , vol.404 , pp. 402-407
    • Sun, Z.1
  • 70
    • 0033625869 scopus 로고    scopus 로고
    • Protein kinase C?: A new essential superstar on the T-cell stage
    • (2000) Immunol. Today , vol.21 , pp. 567-573
    • Altman, A.1
  • 72
    • 17744386318 scopus 로고    scopus 로고
    • Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure
    • (2001) Cell , vol.104 , pp. 33-42
    • Ruland, J.1
  • 73
  • 74
    • 0035374349 scopus 로고    scopus 로고
    • Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-κB signaling pathway
    • (2001) J. Biol. Chem. , vol.276 , pp. 19012-19019
    • Lucas, P.C.1
  • 75
    • 0037075551 scopus 로고    scopus 로고
    • RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
    • (2002) Nature , vol.416 , pp. 194-199
    • Kobayashi, K.1
  • 76
    • 0033230122 scopus 로고    scopus 로고
    • Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family
    • (1999) BioEssays , vol.21 , pp. 912-921
    • Dimitratos, S.D.1
  • 77
    • 0035843970 scopus 로고    scopus 로고
    • Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-κB activation
    • (2001) FEBS Lett. , vol.496 , pp. 121-127
    • Gaide, O.1
  • 78
    • 0035853841 scopus 로고    scopus 로고
    • CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-κB
    • (2001) J. Biol. Chem. , vol.276 , pp. 11877-11882
    • Bertin, J.1
  • 79
    • 0034672054 scopus 로고    scopus 로고
    • The physical association of protein kinase C ? with a lipid raft-associated inhibitor of κ B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28
    • (2000) J. Immunol. , vol.165 , pp. 6933-6940
    • Khoshnan, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.