메뉴 건너뛰기




Volumn 39, Issue 5, 2007, Pages 336-340

Alterations of pancreatic beta-cell mass and islet number due to Ins2-controlled expression of Cre recombinase: RIP-Cre revisited; part 2

Author keywords

C57BL 6; Cre recombinase; Cre loxP; Diabetes; Glucose metabolism; Insulin secretion; Islet of Langerhans; Mouse models; Pancreatic beta cell; Transgene

Indexed keywords

CRE RECOMBINASE; INSULIN;

EID: 34249946918     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-976538     Document Type: Article
Times cited : (30)

References (35)
  • 4
    • 25144464664 scopus 로고    scopus 로고
    • Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance
    • Dai C, Huh CG, Thorgeirsson SS, Liu Y. Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance. Am J Pathol 2005; 167: 429-436
    • (2005) Am J Pathol , vol.167 , pp. 429-436
    • Dai, C.1    Huh, C.G.2    Thorgeirsson, S.S.3    Liu, Y.4
  • 5
    • 21344442148 scopus 로고    scopus 로고
    • Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass
    • Roccisana J, Ready V, Vasavada RC, Gonzalez-Pertusa JA, Magnuson MA, Garcia-Ocana A. Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass. Diabetes 2005; 54: 2090-2102
    • (2005) Diabetes , vol.54 , pp. 2090-2102
    • Roccisana, J.1    Ready, V.2    Vasavada, R.C.3    Gonzalez-Pertusa, J.A.4    Magnuson, M.A.5    Garcia-Ocana, A.6
  • 10
    • 3843127483 scopus 로고    scopus 로고
    • Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release
    • Wang L, Coffinier C, Thomas MK, Gresh L, Eddu G, Manor T, Levitsky LL, Yaniv M, Rhoads DB. Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release. Endocrinology 2004; 145: 3941-3949
    • (2004) Endocrinology , vol.145 , pp. 3941-3949
    • Wang, L.1    Coffinier, C.2    Thomas, M.K.3    Gresh, L.4    Eddu, G.5    Manor, T.6    Levitsky, L.L.7    Yaniv, M.8    Rhoads, D.B.9
  • 13
    • 0036578921 scopus 로고    scopus 로고
    • Beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass
    • Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR. Beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. Nat Genet 2002; 31: 111-115
    • (2002) Nat Genet , vol.31 , pp. 111-115
    • Kulkarni, R.N.1    Holzenberger, M.2    Shih, D.Q.3    Ozcan, U.4    Stoffel, M.5    Magnuson, M.A.6    Kahn, C.R.7
  • 14
    • 0033524937 scopus 로고    scopus 로고
    • Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes
    • Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 1999; 96: 329-339
    • (1999) Cell , vol.96 , pp. 329-339
    • Kulkarni, R.N.1    Brüning, J.C.2    Winnay, J.N.3    Postic, C.4    Magnuson, M.A.5    Kahn, C.R.6
  • 16
    • 9644260563 scopus 로고    scopus 로고
    • Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes
    • Lin X, Taguchi A, Park S, Kushner JA, Li F, Li Y, White MF. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes. J Clin Invest 2004; 114: 908-916
    • (2004) J Clin Invest , vol.114 , pp. 908-916
    • Lin, X.1    Taguchi, A.2    Park, S.3    Kushner, J.A.4    Li, F.5    Li, Y.6    White, M.F.7
  • 19
    • 0041970059 scopus 로고    scopus 로고
    • Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS. Of mice and MEN1: insulinomas in a conditional mouse knockout. Mol Cell Biol 2003; 23: 6075-6085
    • Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS. Of mice and MEN1: insulinomas in a conditional mouse knockout. Mol Cell Biol 2003; 23: 6075-6085
  • 20
    • 1842557785 scopus 로고    scopus 로고
    • Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues
    • Biondi CA, Gartside MG, Waring P, Loffler KA, Stark MS, Magnuson MA, Kay GF, Hayward NK. Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues. Mol Cell Biol 2004; 24: 3125-3131
    • (2004) Mol Cell Biol , vol.24 , pp. 3125-3131
    • Biondi, C.A.1    Gartside, M.G.2    Waring, P.3    Loffler, K.A.4    Stark, M.S.5    Magnuson, M.A.6    Kay, G.F.7    Hayward, N.K.8
  • 24
    • 33645217126 scopus 로고    scopus 로고
    • Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes
    • Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J, Magnuson MA, Wu H. Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol 2006; 26: 2772-2781
    • (2006) Mol Cell Biol , vol.26 , pp. 2772-2781
    • Stiles, B.L.1    Kuralwalla-Martinez, C.2    Guo, W.3    Gregorian, C.4    Wang, Y.5    Tian, J.6    Magnuson, M.A.7    Wu, H.8
  • 27
    • 20444428741 scopus 로고    scopus 로고
    • Wang XP, Yang J, Norman MA, Magnussen J, DeMayo FJ, Brunicardi FC. SSTR5 ablation in islet results in alterations in glucose homeostasis in mice. FEBS Lett 2005; 579: 3107-3114
    • Wang XP, Yang J, Norman MA, Magnussen J, DeMayo FJ, Brunicardi FC. SSTR5 ablation in islet results in alterations in glucose homeostasis in mice. FEBS Lett 2005; 579: 3107-3114
  • 28
    • 0033762782 scopus 로고    scopus 로고
    • Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes
    • Silva JP, Kohler M, Graffe, Oldfors A, Magnuson MA, Berggren PO, Larsson NG. Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes. Nat Genet 2000; 26: 336-340
    • (2000) Nat Genet , vol.26 , pp. 336-340
    • Silva, J.P.1    Kohler, M.2    Graffe3    Oldfors, A.4    Magnuson, M.A.5    Berggren, P.O.6    Larsson, N.G.7
  • 30
    • 0019765934 scopus 로고
    • Effect of variations in islet size and shape on glucose-stimulated insulin secretion
    • Reaven EP, Gold G, Walker W, Reaven GM. Effect of variations in islet size and shape on glucose-stimulated insulin secretion. Horm Metab Res 1981; 13: 673-674
    • (1981) Horm Metab Res , vol.13 , pp. 673-674
    • Reaven, E.P.1    Gold, G.2    Walker, W.3    Reaven, G.M.4
  • 31
    • 0016286635 scopus 로고
    • The hyperplastic pancreatic islet as the cause of insulin resistance in obesity
    • Mahler RJ. The hyperplastic pancreatic islet as the cause of insulin resistance in obesity. Horm Metab Res 1974; 4: 172-174
    • (1974) Horm Metab Res , vol.4 , pp. 172-174
    • RJ, M.1
  • 32
    • 0021063044 scopus 로고
    • Temporal changes in pancreatic islet composition in C57BL/6J-db/db (diabetes) mice
    • Gapp DA, Leiter EH, Coleman DL, Schwizer RW. Temporal changes in pancreatic islet composition in C57BL/6J-db/db (diabetes) mice. Diabetologia 1983; 25: 439-443
    • (1983) Diabetologia , vol.25 , pp. 439-443
    • Gapp, D.A.1    Leiter, E.H.2    Coleman, D.L.3    Schwizer, R.W.4
  • 33
    • 23944525524 scopus 로고    scopus 로고
    • Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: Evidence for specificity of impaired beta cell adaptation
    • Hull RL, Kodama K, Utzschneider KM, Can DB, Prigeon RL, Kahn SE. Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation. Diabetologia 2005; 48: 1350-1358
    • (2005) Diabetologia , vol.48 , pp. 1350-1358
    • Hull, R.L.1    Kodama, K.2    Utzschneider, K.M.3    Can, D.B.4    Prigeon, R.L.5    Kahn, S.E.6
  • 34
    • 0034121735 scopus 로고    scopus 로고
    • Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
    • Herrera PL. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000; 127: 2317-2322
    • (2000) Development , vol.127 , pp. 2317-2322
    • PL, H.1
  • 35
    • 0032525981 scopus 로고    scopus 로고
    • Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U, Jonsson J, Jonsson L, Simu K, Edlund H. Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev 1998; 12: 1763-1768
    • (1998) Genes Dev , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.