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Volumn 24, Issue 1, 2004, Pages 258-269

Essential Role of STAT3 in Body Weight and Glucose Homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; GENOMIC DNA; INSULIN; MESSENGER RNA; RECOMBINANT LEPTIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR;

EID: 10744232925     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.1.258-269.2004     Document Type: Article
Times cited : (128)

References (46)
  • 2
    • 0032934156 scopus 로고    scopus 로고
    • Functional roles of STAT family proteins: Lessons from knockout mice
    • Akira, S. 1999. Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells 17:138-146.
    • (1999) Stem Cells , vol.17 , pp. 138-146
    • Akira, S.1
  • 3
    • 0034657958 scopus 로고    scopus 로고
    • Roles of STAT3 defined by tissue-specific gene targeting
    • Akira, S. 2000. Roles of STAT3 defined by tissue-specific gene targeting. Oncogene 19:2607-2611.
    • (2000) Oncogene , vol.19 , pp. 2607-2611
    • Akira, S.1
  • 4
    • 0035131190 scopus 로고    scopus 로고
    • Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene activation in the liver
    • Alonzi, T., D. Maritano, B. Gorgoni, G. Rizzuto, C. Libert, and V. Poli. 2001. Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene activation in the liver. Mol. Cell. Biol. 21:1621-1632.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1621-1632
    • Alonzi, T.1    Maritano, D.2    Gorgoni, B.3    Rizzuto, G.4    Libert, C.5    Poli, V.6
  • 11
    • 0032767535 scopus 로고    scopus 로고
    • Identification and function of neonatal Fc receptor in mammary gland of lactating mice
    • Cianga, P., C. Medesan, J. A. Richardson, V. Ghetie, and E. S. Ward. 1999. Identification and function of neonatal Fc receptor in mammary gland of lactating mice. Eur. J. Immunol. 29:2515-2523.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2515-2523
    • Cianga, P.1    Medesan, C.2    Richardson, J.A.3    Ghetie, V.4    Ward, E.S.5
  • 12
    • 0029006437 scopus 로고
    • Tissue-specific expression of the rat insulin 1 gene in vivo requires both the enhancer and promoter regions
    • Dandoy-Dron, F., J. M. Itier, E. Monthioux, D. Bucchini, and J. Jami. 1995. Tissue-specific expression of the rat insulin 1 gene in vivo requires both the enhancer and promoter regions. Differentiation 58:291-295.
    • (1995) Differentiation , vol.58 , pp. 291-295
    • Dandoy-Dron, F.1    Itier, J.M.2    Monthioux, E.3    Bucchini, D.4    Jami, J.5
  • 13
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell, J. E. 1997. STATs and gene regulation. Science 277:1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell, J.E.1
  • 15
    • 0033711946 scopus 로고    scopus 로고
    • Down-regulated STAT3 messenger ribonucleic acid and STAT3 protein in the hypothalamic arcuate nucleus of the obese leptin-deficient (ob/ob) mouse
    • Hakansson-Ovesjo, M. L., M. Collin, and B. Meister. 2000. Down-regulated STAT3 messenger ribonucleic acid and STAT3 protein in the hypothalamic arcuate nucleus of the obese leptin-deficient (ob/ob) mouse. Endocrinology 141:3946-3955.
    • (2000) Endocrinology , vol.141 , pp. 3946-3955
    • Hakansson-Ovesjo, M.L.1    Collin, M.2    Meister, B.3
  • 18
    • 0034198919 scopus 로고    scopus 로고
    • Leptin: A multifunctional hormone
    • Huang, L., and C. Li. 2000. Leptin: a multifunctional hormone. Cell Res. 10:81-92.
    • (2000) Cell Res. , vol.10 , pp. 81-92
    • Huang, L.1    Li, C.2
  • 19
    • 0035794211 scopus 로고    scopus 로고
    • Modulation of circulating leptin levels by its soluble receptor
    • Huang, L., Z. Wang, and C. Li. 2001. Modulation of circulating leptin levels by its soluble receptor. J. Biol. Chem. 276:6343-6349.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6343-6349
    • Huang, L.1    Wang, Z.2    Li, C.3
  • 20
    • 0035313701 scopus 로고    scopus 로고
    • The Stat family in cytokine signaling
    • Ihle, J. N. 2001. The Stat family in cytokine signaling. Curr. Opin. Cell Biol. 13:211-217.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 211-217
    • Ihle, J.N.1
  • 21
    • 0037066787 scopus 로고    scopus 로고
    • Stat3 deficiency in keratinocytes leads to compromised cell migration through hyperphosphorylation of p130Cas
    • Kira, M., S. Sano, S. Takagi, K. Yoshikawa, J. Takeda, and S. Itami. 2002. Stat3 deficiency in keratinocytes leads to compromised cell migration through hyperphosphorylation of p130Cas. J. Biol. Chem. 277:12931-12936.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12931-12936
    • Kira, M.1    Sano, S.2    Takagi, S.3    Yoshikawa, K.4    Takeda, J.5    Itami, S.6
  • 22
    • 0033956846 scopus 로고    scopus 로고
    • The db/db mouse, a model for diabetic dyslipidemia: Molecular characterization and effects of Western diet feeding
    • Kobayashi, K., T. M. Forte, S. Taniguchi, B. Y. Ishida, K. Oka, and L. Chan. 2000. The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding. Metabolism 49:22-31.
    • (2000) Metabolism , vol.49 , pp. 22-31
    • Kobayashi, K.1    Forte, T.M.2    Taniguchi, S.3    Ishida, B.Y.4    Oka, K.5    Chan, L.6
  • 23
    • 0033524937 scopus 로고    scopus 로고
    • Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes
    • Kulkarni, R. N., J. C. Bruning, J. N. Winnay, C. Postic, M. A. Magnuson, and C. R. Kahn. 1999. Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96:329-339.
    • (1999) Cell , vol.96 , pp. 329-339
    • Kulkarni, R.N.1    Bruning, J.C.2    Winnay, J.N.3    Postic, C.4    Magnuson, M.A.5    Kahn, C.R.6
  • 24
    • 0036578921 scopus 로고    scopus 로고
    • β-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass
    • Kulkarni, R. N., M. Holzenberger, D. Q. Shih, U. Ozcan, M. Stoffel, M. A. Magnuson, and C. R. Kahn. 2002. β-Cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass. Nat. Genet. 31:111-115.
    • (2002) Nat. Genet. , vol.31 , pp. 111-115
    • Kulkarni, R.N.1    Holzenberger, M.2    Shih, D.Q.3    Ozcan, U.4    Stoffel, M.5    Magnuson, M.A.6    Kahn, C.R.7
  • 26
  • 27
    • 0033578334 scopus 로고    scopus 로고
    • Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction
    • Li, C., and J. M. Friedman. 1999. Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction. Proc. Natl. Acad. Sci. USA 96:9677-9682.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9677-9682
    • Li, C.1    Friedman, J.M.2
  • 29
    • 0037181624 scopus 로고    scopus 로고
    • New mouse model to study islet transplantation in insulin-dependent diabetes mellitus
    • Mathews, C. E., S. H. Langley, and E. H. Leiter. 2002. New mouse model to study islet transplantation in insulin-dependent diabetes mellitus. Transplantation 73:1333-1336.
    • (2002) Transplantation , vol.73 , pp. 1333-1336
    • Mathews, C.E.1    Langley, S.H.2    Leiter, E.H.3
  • 30
    • 0035370934 scopus 로고    scopus 로고
    • Lose weight STAT: CNTF tops leptin
    • Mattson, M. P. 2001. Lose weight STAT: CNTF tops leptin. Trends Neurosci. 24:313-314.
    • (2001) Trends Neurosci. , vol.24 , pp. 313-314
    • Mattson, M.P.1
  • 31
    • 0032590079 scopus 로고    scopus 로고
    • Interleukin-1β activates a short STAT-3 isoform in clonal insulin-secreting cells
    • Morton, N. M., R. P. de Groot, M. A. Cawthorne, and V. Emilsson. 1999. Interleukin-1β activates a short STAT-3 isoform in clonal insulin-secreting cells. FEBS Lett. 442:57-60.
    • (1999) FEBS Lett. , vol.442 , pp. 57-60
    • Morton, N.M.1    De Groot, R.P.2    Cawthorne, M.A.3    Emilsson, V.4
  • 33
    • 0034242440 scopus 로고    scopus 로고
    • Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice
    • Nagy, T. R., and A. L. Clair. 2000. Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice. Obes. Res. 8:392-398.
    • (2000) Obes. Res. , vol.8 , pp. 392-398
    • Nagy, T.R.1    Clair, A.L.2
  • 36
    • 0033198793 scopus 로고    scopus 로고
    • Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
    • Sano, S., S. Itami, K. Takeda, M. Tarutani, Y. Yamaguchi, H. Miura, K. Yoshikawa, S. Akira, and J. Takeda. 1999. Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J. 18:4657-4668.
    • (1999) EMBO J. , vol.18 , pp. 4657-4668
    • Sano, S.1    Itami, S.2    Takeda, K.3    Tarutani, M.4    Yamaguchi, Y.5    Miura, H.6    Yoshikawa, K.7    Akira, S.8    Takeda, J.9
  • 37
    • 0034868746 scopus 로고    scopus 로고
    • Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival
    • Sano, S., Y. Takahama, T. Sugawara, H. Kosaka, S. Itami, K. Yoshikawa, J. Miyazaki, W. van Ewijk, and J. Takeda. 2001. Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival. Immunity 15:261-273.
    • (2001) Immunity , vol.15 , pp. 261-273
    • Sano, S.1    Takahama, Y.2    Sugawara, T.3    Kosaka, H.4    Itami, S.5    Yoshikawa, K.6    Miyazaki, J.7    Van Ewijk, W.8    Takeda, J.9
  • 38
    • 0036256836 scopus 로고    scopus 로고
    • Series introduction: JAK-STAT signaling in human disease
    • Schindler, C. W. 2002. Series introduction: JAK-STAT signaling in human disease. J. Clin. Investig. 109:1133-1137.
    • (2002) J. Clin. Investig. , vol.109 , pp. 1133-1137
    • Schindler, C.W.1
  • 39
    • 0037148523 scopus 로고    scopus 로고
    • Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult
    • Schweizer, U., J. Gunnersen, C. Karch, S. Wiese, B. Holtmann, IL Takeda, S. Akira, and M. Sendtner. 2002. Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. J. Cell Biol. 156:287-298.
    • (2002) J. Cell Biol. , vol.156 , pp. 287-298
    • Schweizer, U.1    Gunnersen, J.2    Karch, C.3    Wiese, S.4    Holtmann, B.5    Takeda, I.L.6    Akira, S.7    Sendtner, M.8
  • 40
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano, P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21:70-71.
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 41
    • 0035238466 scopus 로고    scopus 로고
    • Multi-functional roles of Stat3 revealed by conditional gene targeting
    • Takeda, K., and S. Akira. 2001. Multi-functional roles of Stat3 revealed by conditional gene targeting. Arch. Immunol. Ther. Exp. 49:279-283.
    • (2001) Arch. Immunol. Ther. Exp. , vol.49 , pp. 279-283
    • Takeda, K.1    Akira, S.2
  • 42
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
    • Takeda, K., B. E. Clausen, T. Kaisho, T. Tsujimura, N. Terada, I. Forster, and S. Akira. 1999. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10:39-49.
    • (1999) Immunity , vol.10 , pp. 39-49
    • Takeda, K.1    Clausen, B.E.2    Kaisho, T.3    Tsujimura, T.4    Terada, N.5    Forster, I.6    Akira, S.7
  • 43
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
    • Takeda, K., T. Kaisho, N. Yoshida, J. Takeda, T. Kishimoto, and S. Akira. 1998. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J. Immunol. 161:4652-4660.
    • (1998) J. Immunol. , vol.161 , pp. 4652-4660
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5    Akira, S.6
  • 45
    • 0029739826 scopus 로고    scopus 로고
    • Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
    • Vaisse, C., J. L. Halaas, C. M. Horvath, J. E. Darnell, Jr., M. Stoffel, and J. M. Friedman. 1996. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat. Genet. 14:95-97.
    • (1996) Nat. Genet. , vol.14 , pp. 95-97
    • Vaisse, C.1    Halaas, J.L.2    Horvath, C.M.3    Darnell Jr., J.E.4    Stoffel, M.5    Friedman, J.M.6
  • 46
    • 0034686028 scopus 로고    scopus 로고
    • Targeted expression of placental lactogen in the β cells of transgenic mice results in β-cell proliferation, islet mass augmentation, and hypoglycemia
    • Vasavada, R. C., A. Garcia-Ocana, W. S. Zawalich, R. L. Sorenson, P. Dann, M. Syed, L. Ogren, F. Talamantes, and A. F. Stewart. 2000. Targeted expression of placental lactogen in the β cells of transgenic mice results in β-cell proliferation, islet mass augmentation, and hypoglycemia. J. Biol. Chem. 275:15399-15406.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15399-15406
    • Vasavada, R.C.1    Garcia-Ocana, A.2    Zawalich, W.S.3    Sorenson, R.L.4    Dann, P.5    Syed, M.6    Ogren, L.7    Talamantes, F.8    Stewart, A.F.9


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