-
1
-
-
0037114644
-
Low levels of ABCG2 expression in adult AML blast samples
-
Abbott BL, Colapietro AM, Barnes Y, Marini F, Andreeff M, Sorrentino BP (2002). Low levels of ABCG2 expression in adult AML blast samples. Blood 100: 4594-4601.
-
(2002)
Blood
, vol.100
, pp. 4594-4601
-
-
Abbott, B.L.1
Colapietro, A.M.2
Barnes, Y.3
Marini, F.4
Andreeff, M.5
Sorrentino, B.P.6
-
2
-
-
0037089528
-
A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance
-
Allen JD, Jackson SC, Schinkel AH (2002a). A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance. Cancer Res 62: 2294-2299.
-
(2002)
Cancer Res
, vol.62
, pp. 2294-2299
-
-
Allen, J.D.1
Jackson, S.C.2
Schinkel, A.H.3
-
3
-
-
0000890967
-
Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C
-
Allen JD, Van Loevezijn A, Lakhai JM, Van Der Valk M, Van Tellingen O, Reid G et al. (2002b). Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. Mol Cancer Ther 1: 417-425.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 417-425
-
-
Allen, J.D.1
Van Loevezijn, A.2
Lakhai, J.M.3
Van Der Valk, M.4
Van Tellingen, O.5
Reid, G.6
-
4
-
-
0029820166
-
Characterization of the human ABC superfamily: Isolation and mapping of 21 new genes using the expressed sequence tags database
-
Allikmets R, Gerrand B, Hutchinson A, Dean M (1996). Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. Hum Mol Genet 5: 1649-1655.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1649-1655
-
-
Allikmets, R.1
Gerrand, B.2
Hutchinson, A.3
Dean, M.4
-
5
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, Dean M (1998). A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res 58: 5337-5339.
-
(1998)
Cancer Res
, vol.58
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
6
-
-
23844530574
-
Oligomerization of the human ABC transporter ABCG2: Evaluation of the native protein and chimeric dimers
-
Bhatia A, Schafer HJ, Hrycyna CA (2005). Oligomerization of the human ABC transporter ABCG2: evaluation of the native protein and chimeric dimers. Biochemistry 44: 10893-10904.
-
(2005)
Biochemistry
, vol.44
, pp. 10893-10904
-
-
Bhatia, A.1
Schafer, H.J.2
Hrycyna, C.A.3
-
7
-
-
16844384057
-
The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (gleevec): Implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable brain penetration of imatinib in patients
-
Breedveld P, Pluim D, Cipriani G, Wielinga P, Van Tellingen O, Schinkel AH et al. (2005). The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable brain penetration of imatinib in patients. Cancer Res 65: 2577-2582.
-
(2005)
Cancer Res
, vol.65
, pp. 2577-2582
-
-
Breedveld, P.1
Pluim, D.2
Cipriani, G.3
Wielinga, P.4
Van Tellingen, O.5
Schinkel, A.H.6
-
8
-
-
4143142207
-
Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: Potential role for breast cancer resistance protein in clinical drug-drug interactions
-
Breedveld P, Zelcer N, Pluim D, Sonmezer O, Tibben MM, Beijnen JH et al. (2004). Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. Cancer Res 64: 5804-5811.
-
(2004)
Cancer Res
, vol.64
, pp. 5804-5811
-
-
Breedveld, P.1
Zelcer, N.2
Pluim, D.3
Sonmezer, O.4
Tibben, M.M.5
Beijnen, J.H.6
-
9
-
-
0042354831
-
Transport of methotrexate, methotrexate polyglutamines, and 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport
-
Chen ZS, Robey RW, Belinsky MG, Schvaveleva I, Ren XO, Sugimoto Y et al. (2003). Transport of methotrexate, methotrexate polyglutamines, and 17-(β-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport. Cancer Res 63: 4048-4054.
-
(2003)
Cancer Res
, vol.63
, pp. 4048-4054
-
-
Chen, Z.S.1
Robey, R.W.2
Belinsky, M.G.3
Schvaveleva, I.4
Ren, X.O.5
Sugimoto, Y.6
-
10
-
-
33750478648
-
Multiple drug binding sites on the R482G isoform of the ABCG2 transporter
-
Clark R, Kerr I, Callaghan R (2006). Multiple drug binding sites on the R482G isoform of the ABCG2 transporter. Br J Pharmacol 149: 506-515.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 506-515
-
-
Clark, R.1
Kerr, I.2
Callaghan, R.3
-
11
-
-
0037113346
-
Localisation of breast cancer resistance protein in microvessel endothelium of human brain
-
Cooray HC, Blackmore CG, Maskell L, Barrand MA (2002). Localisation of breast cancer resistance protein in microvessel endothelium of human brain. Neuroreport 13: 2059-2063.
-
(2002)
Neuroreport
, vol.13
, pp. 2059-2063
-
-
Cooray, H.C.1
Blackmore, C.G.2
Maskell, L.3
Barrand, M.A.4
-
12
-
-
1642504340
-
Interaction of the breast cancer resistance protein with plant polyphenols
-
Cooray HC, Janvilisri T, Van Veen HW, Hladky SB, Barrand MA (2004). Interaction of the breast cancer resistance protein with plant polyphenols. Biochem Biophys Res Commun 317: 269-275.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 269-275
-
-
Cooray, H.C.1
Janvilisri, T.2
Van Veen, H.W.3
Hladky, S.B.4
Barrand, M.A.5
-
13
-
-
32044437970
-
Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids
-
Cooray HC, Shahi S, Cahn AP, Van Veen HW, Hladky SB, Barrand MA (2006). Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids. Eur J Pharmacol 531: 25-33.
-
(2006)
Eur J Pharmacol
, vol.531
, pp. 25-33
-
-
Cooray, H.C.1
Shahi, S.2
Cahn, A.P.3
Van Veen, H.W.4
Hladky, S.B.5
Barrand, M.A.6
-
14
-
-
0023897681
-
Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone
-
Dalton WS, Cress AE, Alberts DS, Trent JM (1988). Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone. Cancer Res 48: 1882-1888.
-
(1988)
Cancer Res
, vol.48
, pp. 1882-1888
-
-
Dalton, W.S.1
Cress, A.E.2
Alberts, D.S.3
Trent, J.M.4
-
15
-
-
0032695270
-
Reversal of resistance by GF120918 in cell lines expressing the ABC halftransporter MXR
-
De Bruin M, Miyake K, Litman T, Robey R, Bates SE (1999). Reversal of resistance by GF120918 in cell lines expressing the ABC halftransporter MXR. Cancer Lett 146: 117-126.
-
(1999)
Cancer Lett
, vol.146
, pp. 117-126
-
-
De Bruin, M.1
Miyake, K.2
Litman, T.3
Robey, R.4
Bates, S.E.5
-
16
-
-
18244376403
-
Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters
-
Di Pietro A, Conseil G, Pérez-Victoria JM, Dayan G, Baubichon-Cortay H, Trompier D et al. (2002). Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell Mol Life Sci 59: 307-322.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 307-322
-
-
Di Pietro, A.1
Conseil, G.2
Pérez-Victoria, J.M.3
Dayan, G.4
Baubichon-Cortay, H.5
Trompier, D.6
-
17
-
-
0036772386
-
Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffinembedded material
-
Diestra JE, Scheffer GL, Catala II, Maliepaard M, Schnellens JH, Scheper RJ et al. (2002). Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffinembedded material. J Pathol 198: 213-219.
-
(2002)
J Pathol
, vol.198
, pp. 213-219
-
-
Diestra, J.E.1
Scheffer, G.L.2
Catala, I.I.3
Maliepaard, M.4
Schnellens, J.H.5
Scheper, R.J.6
-
18
-
-
0029144936
-
Gender affects doxorubicin pharmacokinetics in patients with normal liver biochemistry
-
Dobbs NA, Twelves CJ, Gillies H, James CA, Harper PG, Rubens RD (1995). Gender affects doxorubicin pharmacokinetics in patients with normal liver biochemistry. Cancer Chemother Pharmacol 36: 473-476.
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 473-476
-
-
Dobbs, N.A.1
Twelves, C.J.2
Gillies, H.3
James, C.A.4
Harper, P.G.5
Rubens, R.D.6
-
19
-
-
0028837002
-
Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulates in leukaemic blast cells
-
Doyle LA, Ross DD, Sridhara R, Fojo AT, Kaufmann SH, Lee EJ et al. (1995). Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulates in leukaemic blast cells. Br J Cancer 71: 52-58.
-
(1995)
Br J Cancer
, vol.71
, pp. 52-58
-
-
Doyle, L.A.1
Ross, D.D.2
Sridhara, R.3
Fojo, A.T.4
Kaufmann, S.H.5
Lee, E.J.6
-
20
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK et al. (1998). A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 95: 15665-15670.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
-
21
-
-
27144483358
-
Identification of ABCG2 as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists
-
Ebert B, Seidel A, Lampen A (2005). Identification of ABCG2 as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. Carcinogenesis 26: 1754-1763.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1754-1763
-
-
Ebert, B.1
Seidel, A.2
Lampen, A.3
-
22
-
-
12344330537
-
Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference
-
Ee PL, He X, Ross DD, Beck WT (2004a). Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. Mol Cancer Ther 3: 1577-1583.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1577-1583
-
-
Ee, P.L.1
He, X.2
Ross, D.D.3
Beck, W.T.4
-
23
-
-
1242293680
-
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene
-
Ee PL, Kamalakaran S, Tonetii D, He X, Ross DD, Beck WT (2004b). Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene. Cancer Res 64: 1247-1251.
-
(2004)
Cancer Res
, vol.64
, pp. 1247-1251
-
-
Ee, P.L.1
Kamalakaran, S.2
Tonetii, D.3
He, X.4
Ross, D.D.5
Beck, W.T.6
-
24
-
-
33745726722
-
The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding
-
Ejendal KFK, Diop NK, Schweiger LC, Hrycyna CA (2006). The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding. Protein Sci 15: 1597-1607.
-
(2006)
Protein Sci
, vol.15
, pp. 1597-1607
-
-
Ejendal, K.F.K.1
Diop, N.K.2
Schweiger, L.C.3
Hrycyna, C.A.4
-
25
-
-
0036554732
-
Expression of the breast cancer resistance protein in breast cancer
-
Faneyte IF, Kristel PM, Maliepaard M, Scheffer GL, Scheper RJ, Schellens JH et al. (2002). Expression of the breast cancer resistance protein in breast cancer. Clin Cancer Res 8: 1068-1074.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1068-1074
-
-
Faneyte, I.F.1
Kristel, P.M.2
Maliepaard, M.3
Scheffer, G.L.4
Scheper, R.J.5
Schellens, J.H.6
-
26
-
-
33645930969
-
Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues
-
Fetsch PA, Abati A, Litman T, Morisaki K, Honjo Y, Mittal K et al. (2006). Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues. Cancer Lett 235: 84-92.
-
(2006)
Cancer Lett
, vol.235
, pp. 84-92
-
-
Fetsch, P.A.1
Abati, A.2
Litman, T.3
Morisaki, K.4
Honjo, Y.5
Mittal, K.6
-
27
-
-
0344393732
-
Strategies for reversing drug resistance
-
Fojo T, Bates S (2003). Strategies for reversing drug resistance. Oncogene 22: 7512-7523.
-
(2003)
Oncogene
, vol.22
, pp. 7512-7523
-
-
Fojo, T.1
Bates, S.2
-
28
-
-
0034086522
-
Population pharmacokinetic model for topotecan derived from phase I clinical trials
-
Gallo JM, Laub PB, Rowinsky EK, Grochow LB, Baker SD (2000). Population pharmacokinetic model for topotecan derived from phase I clinical trials. J Clin Oncol 18: 2459-2467.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2459-2467
-
-
Gallo, J.M.1
Laub, P.B.2
Rowinsky, E.K.3
Grochow, L.B.4
Baker, S.D.5
-
29
-
-
0031435428
-
Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
-
Goodell MA, Rosenzweig M, Kim H, Marks DF, Demaria M, Paradis G et al. (1997). Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med 3: 1337-1345.
-
(1997)
Nat Med
, vol.3
, pp. 1337-1345
-
-
Goodell, M.A.1
Rosenzweig, M.2
Kim, H.3
Marks, D.F.4
Demaria, M.5
Paradis, G.6
-
30
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman MM, Fojo T, Bates SE (2002). Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2: 48-58.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
31
-
-
0036731990
-
Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permit their transport to the apical surface
-
Graf GA, Li WP, Gerard RD, Gelissen I, White A, Cohen JC et al. (2002). Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permit their transport to the apical surface. J Clin Invest 110: 659-669.
-
(2002)
J Clin Invest
, vol.110
, pp. 659-669
-
-
Graf, G.A.1
Li, W.P.2
Gerard, R.D.3
Gelissen, I.4
White, A.5
Cohen, J.C.6
-
32
-
-
0042143281
-
Targeted prodrug design to optimise drug delivery
-
Han HK, Amidon GL (2000). Targeted prodrug design to optimise drug delivery. AAPS PharmSci 2: E6.
-
(2000)
AAPS PharmSci
, vol.2
-
-
Han, H.K.1
Amidon, G.L.2
-
33
-
-
0036849077
-
The biochemistry and medical significance of the flavonoids
-
Havsteen BH (2002). The biochemistry and medical significance of the flavonoids. Pharmacol Ther 96: 67-202.
-
(2002)
Pharmacol Ther
, vol.96
, pp. 67-202
-
-
Havsteen, B.H.1
-
34
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins CF (1992). ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8: 67-113.
-
(1992)
Annu Rev Cell Biol
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
35
-
-
0035884595
-
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
-
Honjo Y, Hrycyna CA, Yan QW, Medina-Perez WY, Robey RW, Van De Laar A et al. (2001). Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells. Cancer Res 61: 6635-6639.
-
(2001)
Cancer Res
, vol.61
, pp. 6635-6639
-
-
Honjo, Y.1
Hrycyna, C.A.2
Yan, Q.W.3
Medina-Perez, W.Y.4
Robey, R.W.5
Van De Laar, A.6
-
36
-
-
2942586678
-
Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression
-
Ifergan I, Shafran A, Jansen G, Hooijberg JH, Scheffer GL, Assaraf YG (2004). Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. J Biol Chem 279: 25527-25534.
-
(2004)
J Biol Chem
, vol.279
, pp. 25527-25534
-
-
Ifergan, I.1
Shafran, A.2
Jansen, G.3
Hooijberg, J.H.4
Scheffer, G.L.5
Assaraf, Y.G.6
-
37
-
-
0042856460
-
Breast cancer resistance protein exports sulfated estrogens but not free estrogens
-
Imai Y, Asada S, Tsukahara S, Ishikawa E, Tsuruo T, Sugimoto Y (2003). Breast cancer resistance protein exports sulfated estrogens but not free estrogens. Mol Pharmacol 64: 610-618.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 610-618
-
-
Imai, Y.1
Asada, S.2
Tsukahara, S.3
Ishikawa, E.4
Tsuruo, T.5
Sugimoto, Y.6
-
38
-
-
12544251673
-
Estrogen-mediated post transcription down-regulation of breast cancer resistance protein/ABCG2
-
Imai Y, Ishikawa E, Asada S, Sugimoto Y (2005). Estrogen-mediated post transcription down-regulation of breast cancer resistance protein/ABCG2. Cancer Res 65: 596-604.
-
(2005)
Cancer Res
, vol.65
, pp. 596-604
-
-
Imai, Y.1
Ishikawa, E.2
Asada, S.3
Sugimoto, Y.4
-
39
-
-
0036598543
-
C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance
-
Imai Y, Nakane M, Kage K, Tsukahara S, Ishikawa E, Tsuruo T et al. (2002a). C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Mol Cancer Ther 1: 611-616.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 611-616
-
-
Imai, Y.1
Nakane, M.2
Kage, K.3
Tsukahara, S.4
Ishikawa, E.5
Tsuruo, T.6
-
40
-
-
3042569646
-
Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
-
Imai Y, Tsukahara S, Asada S, Sugimoto Y (2004). Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res 64: 4346-4352.
-
(2004)
Cancer Res
, vol.64
, pp. 4346-4352
-
-
Imai, Y.1
Tsukahara, S.2
Asada, S.3
Sugimoto, Y.4
-
41
-
-
0036011103
-
Estrone and 17-β-estradiol reverse breast cancer resistance protein-mediated multidrug resistance
-
Imai Y, Tsukahara S, Ishikawa E, Tsuruo T, Sugimoto Y (2002b). Estrone and 17-β-estradiol reverse breast cancer resistance protein-mediated multidrug resistance. Jpn J Cancer Res 93: 231-235.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 231-235
-
-
Imai, Y.1
Tsukahara, S.2
Ishikawa, E.3
Tsuruo, T.4
Sugimoto, Y.5
-
42
-
-
12844280511
-
Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2)
-
Janvilisri T, Shahi S, Venter H, Balakrishnan L, Van Veen HW (2005). Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2). Biochem J 385: 419-426.
-
(2005)
Biochem J
, vol.385
, pp. 419-426
-
-
Janvilisri, T.1
Shahi, S.2
Venter, H.3
Balakrishnan, L.4
Van Veen, H.W.5
-
43
-
-
0038757689
-
Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis
-
Janvilisri T, Venter H, Shahi S, Reuter G, Balakrishnan L, Van Veen HW (2003). Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. J Biol Chem 278: 20645-20651.
-
(2003)
J Biol Chem
, vol.278
, pp. 20645-20651
-
-
Janvilisri, T.1
Venter, H.2
Shahi, S.3
Reuter, G.4
Balakrishnan, L.5
Van Veen, H.W.6
-
44
-
-
33744548409
-
Metabolites of ginsenosides as novel BCRP inhibitors
-
Jin J, Shahi S, Kang HK, Van Veen HW, Fan TP (2006). Metabolites of ginsenosides as novel BCRP inhibitors. Biochem Biophys Res Commun 345: 1308-1314.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1308-1314
-
-
Jin, J.1
Shahi, S.2
Kang, H.K.3
Van Veen, H.W.4
Fan, T.P.5
-
45
-
-
0037180446
-
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
-
Jonker JW, Buitelaar M, Wagenaar E, Van Der Valk MA, Scheffer GL, Scheper RJ et al. (2002). The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci USA 99: 15649-15654.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15649-15654
-
-
Jonker, J.W.1
Buitelaar, M.2
Wagenaar, E.3
Van Der Valk, M.A.4
Scheffer, G.L.5
Scheper, R.J.6
-
46
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
-
Jonker JW, Merino G, Musters S, Van Herwaarden AE, Bolscher E, Wagenaar E et al. (2005). The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nat Med 11: 127-129.
-
(2005)
Nat Med
, vol.11
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
Van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
-
47
-
-
0034684120
-
Role of breast cancer resistance protein in the bioavailability of fetal penetration of topotecan
-
Jonker JW, Smit JW, Brinkhuis RF, Maliepaard M, Beijnen JH, Schellens JHM et al. (2000). Role of breast cancer resistance protein in the bioavailability of fetal penetration of topotecan. J Natl Cancer Inst 92: 1651-1656.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1651-1656
-
-
Jonker, J.W.1
Smit, J.W.2
Brinkhuis, R.F.3
Maliepaard, M.4
Beijnen, J.H.5
Schellens, J.H.M.6
-
48
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano RL, Ling V (1976). A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 445: 152-162.
-
(1976)
Biochim Biophys Acta
, vol.445
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
49
-
-
0037050736
-
Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization
-
Kage K, Tsukahara S, Sugiyama T, Asada S, Ishikawa E, Tsuruo T et al. (2002). Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization. Int J Cancer 97: 626-630.
-
(2002)
Int J Cancer
, vol.97
, pp. 626-630
-
-
Kage, K.1
Tsukahara, S.2
Sugiyama, T.3
Asada, S.4
Ishikawa, E.5
Tsuruo, T.6
-
50
-
-
0035012619
-
Expression of multidrug resistance-related transporters in human breast carcinoma
-
Kanzaki A, Toi M, Nakayama K, Bando H, Mutoh M, Uchida T et al. (2001). Expression of multidrug resistance-related transporters in human breast carcinoma. Jpn J Cancer Res 92: 452-458.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 452-458
-
-
Kanzaki, A.1
Toi, M.2
Nakayama, K.3
Bando, H.4
Mutoh, M.5
Uchida, T.6
-
51
-
-
0036154828
-
The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
-
Kim M, Turnquist H, Jackson J, Sgagias M, Yan Y, Gong M et al. (2002). The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 8: 22-28.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 22-28
-
-
Kim, M.1
Turnquist, H.2
Jackson, J.3
Sgagias, M.4
Yan, Y.5
Gong, M.6
-
52
-
-
19944399722
-
Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta
-
Kobayashi D, Ieiri I, Hirota T, Takane H, Maegawa S, Kigawa J et al. (2005). Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta. Drug Metab Dispos 33: 94-101.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 94-101
-
-
Kobayashi, D.1
Ieiri, I.2
Hirota, T.3
Takane, H.4
Maegawa, S.5
Kigawa, J.6
-
53
-
-
6344284092
-
Functional analysis of SNP variants of BCRP/ABCG2
-
Kondo C, Suzuki H, Itoda M, Ozawa S, Sawada J, Kobayashi D et al. (2004). Functional analysis of SNP variants of BCRP/ABCG2. Pharm Res 21: 1895-1903.
-
(2004)
Pharm Res
, vol.21
, pp. 1895-1903
-
-
Kondo, C.1
Suzuki, H.2
Itoda, M.3
Ozawa, S.4
Sawada, J.5
Kobayashi, D.6
-
54
-
-
0036019374
-
Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2
-
Kowalski P, Stein U, Scheffer GL, Lage H (2002). Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2. Cancer Gene Ther 9: 579-586.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 579-586
-
-
Kowalski, P.1
Stein, U.2
Scheffer, G.L.3
Lage, H.4
-
55
-
-
0028792273
-
The effects of nonsteroidal antiinflammatory drugs on methotrexate (MTX) pharmacokinetics: Impairment of renal clearance of MTX at weekly maintenance doses but not at 7.5mg
-
Kremer JM, Hamilton RA (1995). The effects of nonsteroidal antiinflammatory drugs on methotrexate (MTX) pharmacokinetics: impairment of renal clearance of MTX at weekly maintenance doses but not at 7.5mg. J Rheumatol 22: 2072-2077.
-
(1995)
J Rheumatol
, vol.22
, pp. 2072-2077
-
-
Kremer, J.M.1
Hamilton, R.A.2
-
56
-
-
0033799839
-
Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs
-
Krishna R, Mayer LD (2000). Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm Sci 11: 265-283.
-
(2000)
Eur J Pharm Sci
, vol.11
, pp. 265-283
-
-
Krishna, R.1
Mayer, L.D.2
-
57
-
-
2642526992
-
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
-
Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE et al. (2004). The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem 279: 24218-24225.
-
(2004)
J Biol Chem
, vol.279
, pp. 24218-24225
-
-
Krishnamurthy, P.1
Ross, D.D.2
Nakanishi, T.3
Bailey-Dell, K.4
Zhou, S.5
Mercer, K.E.6
-
59
-
-
0036644903
-
Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and p-glycoprotein inhibitor GF120918
-
Kruijtzer CMF, Beijnen JH, Rosing H, Ten Bokkel Huinink WW, Schot M, Jewell RC et al. (2002). Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and p-glycoprotein inhibitor GF120918. J Clin Oncol 20: 2943-2950.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2943-2950
-
-
Kruijtzer, C.M.F.1
Beijnen, J.H.2
Rosing, H.3
Ten Bokkel Huinink, W.W.4
Schot, M.5
Jewell, R.C.6
-
60
-
-
33846664466
-
ATP-binding cassette, subfamily G (ABCG family)
-
Kusuhara H, Sugiyama Y (2006). ATP-binding cassette, subfamily G (ABCG family). Pflugers Arch Eur J Physiol 453: 735-744.
-
(2006)
Pflugers Arch Eur J Physiol
, vol.453
, pp. 735-744
-
-
Kusuhara, H.1
Sugiyama, Y.2
-
61
-
-
0141888537
-
The role of ABC transporters in clinical practice
-
Leonard GD, Fojo T, Bates SE (2003). The role of ABC transporters in clinical practice. Oncologist 8: 411-424.
-
(2003)
Oncologist
, vol.8
, pp. 411-424
-
-
Leonard, G.D.1
Fojo, T.2
Bates, S.E.3
-
62
-
-
17544368685
-
Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
-
Leslie EM, Deeley RG, Cole SPC (2005). Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Tox Appl Pharmacol 204: 216-237.
-
(2005)
Tox Appl Pharmacol
, vol.204
, pp. 216-237
-
-
Leslie, E.M.1
Deeley, R.G.2
Cole, S.P.C.3
-
63
-
-
0035033774
-
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids
-
Leslie EM, Mao Q, Oleschuk CJ, Deeley RG, Cole SPC (2001). Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids. Mol Pharmacol 59: 1171-1180.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 1171-1180
-
-
Leslie, E.M.1
Mao, Q.2
Oleschuk, C.J.3
Deeley, R.G.4
Cole, S.P.C.5
-
64
-
-
20144362553
-
Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference
-
Li WT, Zhou GY, Song XR, Chi WL, Ren RM, Wang XW (2005). Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference. Neoplasma 52: 219-224.
-
(2005)
Neoplasma
, vol.52
, pp. 219-224
-
-
Li, W.T.1
Zhou, G.Y.2
Song, X.R.3
Chi, W.L.4
Ren, R.M.5
Wang, X.W.6
-
65
-
-
0034081847
-
The multidrug-resistant phenotype associated with over-expression of the new ABC half-transporter, MXR (ABCG2)
-
Litman T, Brangi M, Hudson E, Fetsch P, Abati A, Ross DD et al. (2000). The multidrug-resistant phenotype associated with over-expression of the new ABC half-transporter, MXR (ABCG2). J Cell Sci 113: 2011-2021.
-
(2000)
J Cell Sci
, vol.113
, pp. 2011-2021
-
-
Litman, T.1
Brangi, M.2
Hudson, E.3
Fetsch, P.4
Abati, A.5
Ross, D.D.6
-
66
-
-
18644367250
-
Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2
-
Litman T, Jensen U, Hansen A, Covitz K, Zhan Z, Fetsch P et al. (2002). Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2. Biochim Biophys Acta 1565: 6-16.
-
(2002)
Biochim Biophys Acta
, vol.1565
, pp. 6-16
-
-
Litman, T.1
Jensen, U.2
Hansen, A.3
Covitz, K.4
Zhan, Z.5
Fetsch, P.6
-
67
-
-
0037412250
-
ABCG subfamily of human ATP-binding cassette proteins
-
Lorkowski S, Cullen P (2002). ABCG subfamily of human ATP-binding cassette proteins. Pure Appl Chem 74: 2057-2081.
-
(2002)
Pure Appl Chem
, vol.74
, pp. 2057-2081
-
-
Lorkowski, S.1
Cullen, P.2
-
68
-
-
0035870289
-
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
-
Maliepaard M, Scheffer GL, Faneyte IF, Van Gastelen MA, Pijnenborg ACLM, Schinkel AH et al. (2001). Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res 61: 3458-3464.
-
(2001)
Cancer Res
, vol.61
, pp. 3458-3464
-
-
Maliepaard, M.1
Scheffer, G.L.2
Faneyte, I.F.3
Van Gastelen, M.A.4
Pijnenborg, A.C.L.M.5
Schinkel, A.H.6
-
69
-
-
0033568540
-
Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line
-
Maliepaard M, Van Gastelen MA, De Jong LA, Pluim D, Van Waardenburg RC, Ruevekamp-Helmer MC et al. (1999). Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line. Cancer Res 59: 4559-4563.
-
(1999)
Cancer Res
, vol.59
, pp. 4559-4563
-
-
Maliepaard, M.1
Van Gastelen, M.A.2
De Jong, L.A.3
Pluim, D.4
Van Waardenburg, R.C.5
Ruevekamp-Helmer, M.C.6
-
70
-
-
27644480743
-
Role of the breast cancer resistance protein (ABCG2) in drug transport
-
Mao Q, Unadkat JD (2005). Role of the breast cancer resistance protein (ABCG2) in drug transport. AAPS J 7: E118-E133.
-
(2005)
AAPS J
, vol.7
-
-
Mao, Q.1
Unadkat, J.D.2
-
71
-
-
33750446035
-
Purification and 3D structural analysis of oligomeric human multidrug transporters ABCG2
-
McDevitt CA, Collins RF, Conway M, Modok S, Storm J, Kerr ID et al. (2006). Purification and 3D structural analysis of oligomeric human multidrug transporters ABCG2. Structure 14: 1623-1632.
-
(2006)
Structure
, vol.14
, pp. 1623-1632
-
-
McDevitt, C.A.1
Collins, R.F.2
Conway, M.3
Modok, S.4
Storm, J.5
Kerr, I.D.6
-
72
-
-
17844372454
-
Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver
-
Merino G, Van Herwaarden AE, Wagenaar E, Jonker JW, Schinkel AH (2005). Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver. Mol Pharmacol 67: 1765-1771.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1765-1771
-
-
Merino, G.1
Van Herwaarden, A.E.2
Wagenaar, E.3
Jonker, J.W.4
Schinkel, A.H.5
-
73
-
-
0242300543
-
Single amino acid substitutions in the transmembrane domain of breast cancer resistance protein (BCRP) alter cross resistance patterns in the transfectants
-
Miwa M, Tsukahara S, Ishikawa E, Asada S, Imai Y, Sugimoto Y (2003). Single amino acid substitutions in the transmembrane domain of breast cancer resistance protein (BCRP) alter cross resistance patterns in the transfectants. Int J Cancer 107: 757-767.
-
(2003)
Int J Cancer
, vol.107
, pp. 757-767
-
-
Miwa, M.1
Tsukahara, S.2
Ishikawa, E.3
Asada, S.4
Imai, Y.5
Sugimoto, Y.6
-
74
-
-
0032895533
-
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistance cells: Demonstration of homology to ABC transporter genes
-
Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Christensen B et al. (1999). Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistance cells: demonstration of homology to ABC transporter genes. Cancer Res 59: 8-13.
-
(1999)
Cancer Res
, vol.59
, pp. 8-13
-
-
Miyake, K.1
Mickley, L.2
Litman, T.3
Zhan, Z.4
Robey, R.5
Christensen, B.6
-
75
-
-
1242319383
-
Single nucleotide polymorphisms result in impaired membrane localization and reduced ATPase activity in multidrug transporter ABCG2
-
Mizuarai S, Aozasa N, Kotani H (2004). Single nucleotide polymorphisms result in impaired membrane localization and reduced ATPase activity in multidrug transporter ABCG2. Int J Cancer 109: 238-246.
-
(2004)
Int J Cancer
, vol.109
, pp. 238-246
-
-
Mizuarai, S.1
Aozasa, N.2
Kotani, H.3
-
76
-
-
4143107239
-
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2- methylamino-4-(3-pyridylmethyl) benzothiasole (E3040) sulphate in breast cancer resistance protein (Bcrp1/Abcg2) knockout mice
-
Mizuno N, Suzuki M, Kusuhara H, Suzuki H, Takeuchi K, Niwa T et al. (2004). Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2- methylamino-4-(3-pyridylmethyl) benzothiasole (E3040) sulphate in breast cancer resistance protein (Bcrp1/Abcg2) knockout mice. Drug Metab Dispos 32: 898-901.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 898-901
-
-
Mizuno, N.1
Suzuki, M.2
Kusuhara, H.3
Suzuki, H.4
Takeuchi, K.5
Niwa, T.6
-
77
-
-
33644755350
-
Molecular modeling of new camptothecin analogues to circumvent ABCG2-mediated drug resistance in cancer
-
Nakagawa H, Saito H, Ikegami Y, Aida-Hyugaji S, Sawada S, Ishikawa T (2005). Molecular modeling of new camptothecin analogues to circumvent ABCG2-mediated drug resistance in cancer. Cancer Lett 234: 81-89.
-
(2005)
Cancer Lett
, vol.234
, pp. 81-89
-
-
Nakagawa, H.1
Saito, H.2
Ikegami, Y.3
Aida-Hyugaji, S.4
Sawada, S.5
Ishikawa, T.6
-
78
-
-
0026496549
-
Reduced intracellular drug accumulation in the absence of p-glycoprotein (MDR1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells
-
Nakagawa M, Schneider E, Dixon KH, Horton J, Kelley K, Morrow C et al. (1992). Reduced intracellular drug accumulation in the absence of p-glycoprotein (MDR1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells. Cancer Res 52: 6175-6181.
-
(1992)
Cancer Res
, vol.52
, pp. 6175-6181
-
-
Nakagawa, M.1
Schneider, E.2
Dixon, K.H.3
Horton, J.4
Kelley, K.5
Morrow, C.6
-
79
-
-
13944269488
-
Gefitinib ('iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance
-
Nakamura Y, Oka M, Soda H, Shiozawa K, Yoshikawa M, Itoh A et al. (2005). Gefitinib ('iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. Cancer Res 65: 1541-1546.
-
(2005)
Cancer Res
, vol.65
, pp. 1541-1546
-
-
Nakamura, Y.1
Oka, M.2
Soda, H.3
Shiozawa, K.4
Yoshikawa, M.5
Itoh, A.6
-
80
-
-
0345735768
-
Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis
-
Nakanishi T, Doyle LA, Hassel B, Wei Y, Bauer KS, Wu S et al. (2003a). Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis. Mol Pharmacol 64: 1452-1462.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1452-1462
-
-
Nakanishi, T.1
Doyle, L.A.2
Hassel, B.3
Wei, Y.4
Bauer, K.S.5
Wu, S.6
-
81
-
-
0042835753
-
Quantitative analysis of breast cancer resistance protein and cellular resistance to flavopiridol in acute leukemia patients
-
Nakanishi T, Karp JE, Tan M, Doyle LA, Peters T, Yang W et al. (2003b). Quantitative analysis of breast cancer resistance protein and cellular resistance to flavopiridol in acute leukemia patients. Clin Cancer Res 9: 3320-3328.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3320-3328
-
-
Nakanishi, T.1
Karp, J.E.2
Tan, M.3
Doyle, L.A.4
Peters, T.5
Yang, W.6
-
82
-
-
0034789387
-
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells
-
Ozvegy C, Litman T, Szakacs G, Nagy Z, Bates SE, Varadi A et al. (2001). Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells. Biochem Biophys Res Commun 285: 111-117.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 111-117
-
-
Ozvegy, C.1
Litman, T.2
Szakacs, G.3
Nagy, Z.4
Bates, S.E.5
Varadi, A.6
-
83
-
-
0037073730
-
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter
-
Ozvegy C, Varadi A, Sarkadi B (2002). Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. J Biol Chem 277: 47980-47990.
-
(2002)
J Biol Chem
, vol.277
, pp. 47980-47990
-
-
Ozvegy, C.1
Varadi, A.2
Sarkadi, B.3
-
84
-
-
12844255054
-
Single amino acid (482) variants of the ABCG2 multidrug transporter: Major differences in transport capacity and substrate recognition
-
Ozvegy-Laczka C, Koblos G, Sarkadi B, Varadi A (2005). Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Biochim Biophys Acta 1668: 53-63.
-
(2005)
Biochim Biophys Acta
, vol.1668
, pp. 53-63
-
-
Ozvegy-Laczka, C.1
Koblos, G.2
Sarkadi, B.3
Varadi, A.4
-
85
-
-
11844284860
-
Human breast cancer resistance protein (BCRP/ABCG2): Interactions with steroid drugs, hormones, the dietary carcinogen PhIP, and transport of cimetidine
-
Pavek P, Merino G, Wagenaar E, Bolscher E, Novotna M, Jonker JW et al. (2005). Human breast cancer resistance protein (BCRP/ABCG2): interactions with steroid drugs, hormones, the dietary carcinogen PhIP, and transport of cimetidine. J Pharmacol Exp Ther 312: 144-152.
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 144-152
-
-
Pavek, P.1
Merino, G.2
Wagenaar, E.3
Bolscher, E.4
Novotna, M.5
Jonker, J.W.6
-
86
-
-
33747216808
-
Purification of breast cancer resistance protein ABCG2 and role of arginine-482
-
Pozza A, Perez-Victoria JM, Sardo A, Ahmed-Belkacem A, Di Pietro A (2006). Purification of breast cancer resistance protein ABCG2 and role of arginine-482. Cell Mol Life Sci 63: 1912-1922.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1912-1922
-
-
Pozza, A.1
Perez-Victoria, J.M.2
Sardo, A.3
Ahmed-Belkacem, A.4
Di Pietro, A.5
-
87
-
-
16844372982
-
Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia
-
Raaijmakers MHGP, De Grouw EPLM, Heuver LHH, Van Der Reijden BA, Jansen JH, Scheper RJ et al. (2005). Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia. Clin Cancer Res 11: 2436-2444.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2436-2444
-
-
Raaijmakers, M.H.G.P.1
De Grouw, E.P.L.M.2
Heuver, L.H.H.3
Van Der Reijden, B.A.4
Jansen, J.H.5
Scheper, R.J.6
-
88
-
-
0032535004
-
Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C
-
Rabindran SK, He H, Singh M, Brown E, Collins KI, Annable T et al. (1998). Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res 58: 5850-5858.
-
(1998)
Cancer Res
, vol.58
, pp. 5850-5858
-
-
Rabindran, S.K.1
He, H.2
Singh, M.3
Brown, E.4
Collins, K.I.5
Annable, T.6
-
89
-
-
0033966957
-
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
-
Rabindran SK, Ross DD, Doyle LA, Yang W, Greenberger LM (2000). Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 60: 47-50.
-
(2000)
Cancer Res
, vol.60
, pp. 47-50
-
-
Rabindran, S.K.1
Ross, D.D.2
Doyle, L.A.3
Yang, W.4
Greenberger, L.M.5
-
91
-
-
0035138482
-
Overexpression of the ATP-binding cassette half transporter, ABCG2 (MXR/BCRP/ABCP1), in flavopiridol-resistant human breast cancer cells
-
Robey RW, Medina-Perez WY, Nishiyama K, Lahusen T, Miyake K, Litman T et al. (2001). Overexpression of the ATP-binding cassette half transporter, ABCG2 (MXR/BCRP/ABCP1), in flavopiridol-resistant human breast cancer cells. Clin Cancer Res 7: 145-152.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 145-152
-
-
Robey, R.W.1
Medina-Perez, W.Y.2
Nishiyama, K.3
Lahusen, T.4
Miyake, K.5
Litman, T.6
-
92
-
-
0034234653
-
Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
-
Ross DD, Karp JE, Chen TT, Doyle LA (2000). Expression of breast cancer resistance protein in blast cells from patients with acute leukemia. Blood 96: 365-368.
-
(2000)
Blood
, vol.96
, pp. 365-368
-
-
Ross, D.D.1
Karp, J.E.2
Chen, T.T.3
Doyle, L.A.4
-
93
-
-
0035726216
-
Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia
-
Sargent JM, Williamson CJ, Maliepaard M, Elgie AW, Scheper RJ, Taylor CG (2001). Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia. Br J Haematol 115: 257-262.
-
(2001)
Br J Haematol
, vol.115
, pp. 257-262
-
-
Sargent, J.M.1
Williamson, C.J.2
Maliepaard, M.3
Elgie, A.W.4
Scheper, R.J.5
Taylor, C.G.6
-
94
-
-
33749488939
-
Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
-
Sarkadi B, Homoloya L, Szakacs G, Varadi A (2006). Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 86: 1179-1236.
-
(2006)
Physiol Rev
, vol.86
, pp. 1179-1236
-
-
Sarkadi, B.1
Homoloya, L.2
Szakacs, G.3
Varadi, A.4
-
95
-
-
0036064629
-
Expression of the BCRP gene (ABCG2/MXR/ABCP) in childhood acute lymphoblastic leukaemia
-
Sauerbrey A, Sell W, Steinbach D, Voigt A, Zintl F (2002). Expression of the BCRP gene (ABCG2/MXR/ABCP) in childhood acute lymphoblastic leukaemia. Br J Haematol 118: 147-150.
-
(2002)
Br J Haematol
, vol.118
, pp. 147-150
-
-
Sauerbrey, A.1
Sell, W.2
Steinbach, D.3
Voigt, A.4
Zintl, F.5
-
96
-
-
0037079708
-
The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
-
Scharenberg CW, Harkey MA, Torok-Storb B (2002). The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 99: 507-512.
-
(2002)
Blood
, vol.99
, pp. 507-512
-
-
Scharenberg, C.W.1
Harkey, M.A.2
Torok-Storb, B.3
-
97
-
-
33645993917
-
New light on multidrug binding by an ATP-binding-cassette transporter
-
Shilling RA, Venter H, Velamakanni S, Bapna A, Woebking B, Shahi S et al. (2006). New light on multidrug binding by an ATP-binding-cassette transporter. Trends Pharmacol Sci 27: 195-203.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 195-203
-
-
Shilling, R.A.1
Venter, H.2
Velamakanni, S.3
Bapna, A.4
Woebking, B.5
Shahi, S.6
-
98
-
-
3042651340
-
Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype
-
Sparreboom A, Gelderblom H, Marsh S, Ahluwalia R, Obach R, Principe P et al. (2004). Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype. Clin Pharmacol Ther 76: 38-44.
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 38-44
-
-
Sparreboom, A.1
Gelderblom, H.2
Marsh, S.3
Ahluwalia, R.4
Obach, R.5
Principe, P.6
-
99
-
-
13444288036
-
-
Staud F, Pavek P (2005). Breast cancer resistance protein (BCRP/ABCG2). Int J Biochem Cell Biol 37: 720-725.
-
Staud F, Pavek P (2005). Breast cancer resistance protein (BCRP/ABCG2). Int J Biochem Cell Biol 37: 720-725.
-
-
-
-
100
-
-
0036052296
-
BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia
-
Steinbach D, Sell W, Voigt A, Hermann J, Zintl F, Sauerbrey A (2002). BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia. Leukemia 16: 1443-1447.
-
(2002)
Leukemia
, vol.16
, pp. 1443-1447
-
-
Steinbach, D.1
Sell, W.2
Voigt, A.3
Hermann, J.4
Zintl, F.5
Sauerbrey, A.6
-
101
-
-
5644264888
-
Gefitinib enhances the antitumour activity and oral bioavailability of irinotecan in mice
-
Stewart CF, Leggas M, Schuetz JD, Panetta JC, Cheshire PJ, Peterson J et al. (2004). Gefitinib enhances the antitumour activity and oral bioavailability of irinotecan in mice. Cancer Res 64: 7491-7499.
-
(2004)
Cancer Res
, vol.64
, pp. 7491-7499
-
-
Stewart, C.F.1
Leggas, M.2
Schuetz, J.D.3
Panetta, J.C.4
Cheshire, P.J.5
Peterson, J.6
-
102
-
-
0034665902
-
Hoechst dye efflux reveals a novel CD7+CD34- lymphoid progenitor in human umbilical cord blood
-
Storms RW, Goodell MA, Fisher A, Mulligan RC, Smith C (2000). Hoechst dye efflux reveals a novel CD7+CD34- lymphoid progenitor in human umbilical cord blood. Blood 96: 2125-2133.
-
(2000)
Blood
, vol.96
, pp. 2125-2133
-
-
Storms, R.W.1
Goodell, M.A.2
Fisher, A.3
Mulligan, R.C.4
Smith, C.5
-
103
-
-
0041309866
-
Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists
-
Sugimoto Y, Tsukahara S, Imai Y, Sugimoto Y, Ueda K, Tsuruo T (2003). Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists. Mol Cancer Ther 2: 105-112.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 105-112
-
-
Sugimoto, Y.1
Tsukahara, S.2
Imai, Y.3
Sugimoto, Y.4
Ueda, K.5
Tsuruo, T.6
-
104
-
-
0016840257
-
Transport defects as the physiological basis for eye color mutants of Drosophila melanogaster
-
Sullivan DT, Sullivan MC (1975). Transport defects as the physiological basis for eye color mutants of Drosophila melanogaster. Biochem Genet 13: 603-613.
-
(1975)
Biochem Genet
, vol.13
, pp. 603-613
-
-
Sullivan, D.T.1
Sullivan, M.C.2
-
105
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
Suzuki M, Suzuki H, Sugimoto Y, Sugiyama Y (2003). ABCG2 transports sulfated conjugates of steroids and xenobiotics. J Biol Chem 278: 22644-22649.
-
(2003)
J Biol Chem
, vol.278
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
106
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM (2006). Targeting multidrug resistance in cancer. Nat Rev Drug Disc 5: 219-234.
-
(2006)
Nat Rev Drug Disc
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
107
-
-
9644282955
-
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
-
Tanaka Y, Slitt AL, Leazer TM, Maher JM, Klaassen CD (2005). Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice. Biochem Biophys Res Commun 326: 181-187.
-
(2005)
Biochem Biophys Res Commun
, vol.326
, pp. 181-187
-
-
Tanaka, Y.1
Slitt, A.L.2
Leazer, T.M.3
Maher, J.M.4
Klaassen, C.D.5
-
108
-
-
0025733402
-
Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line
-
Taylor CW, Dalton WS, Parrish PR, Gleason MC, Bellamy WT, Thompson FH et al. (1991). Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line. Br J Cancer 63: 923-929.
-
(1991)
Br J Cancer
, vol.63
, pp. 923-929
-
-
Taylor, C.W.1
Dalton, W.S.2
Parrish, P.R.3
Gleason, M.C.4
Bellamy, W.T.5
Thompson, F.H.6
-
109
-
-
0027548728
-
The transporters associated with antigen presentation
-
Townsend A, Trowsdale J (1993). The transporters associated with antigen presentation. Semin Cell Biol 4: 53-61.
-
(1993)
Semin Cell Biol
, vol.4
, pp. 53-61
-
-
Townsend, A.1
Trowsdale, J.2
-
110
-
-
0033572627
-
Tissue-specific expression of functional isoforms of mouse folylpoly-γ-glutamate synthetase: A basis for targeting folate antimetabolites
-
Turner FB, Andreassi JF, Ferguson J, Titus S, Tse A, Taylor SM et al. (1999). Tissue-specific expression of functional isoforms of mouse folylpoly-γ-glutamate synthetase: a basis for targeting folate antimetabolites. Cancer Res 59: 6074-6079.
-
(1999)
Cancer Res
, vol.59
, pp. 6074-6079
-
-
Turner, F.B.1
Andreassi, J.F.2
Ferguson, J.3
Titus, S.4
Tse, A.5
Taylor, S.M.6
-
111
-
-
0036100195
-
Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)
-
Van Den Heuvel-Eibrink MM, Weimer EA, Prins A, Meijerink JP, Vossebeld PJ, Van Der Holt B et al. (2002). Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML). Leukemia 16: 833-839.
-
(2002)
Leukemia
, vol.16
, pp. 833-839
-
-
Van Den Heuvel-Eibrink, M.M.1
Weimer, E.A.2
Prins, A.3
Meijerink, J.P.4
Vossebeld, P.J.5
Van Der Holt, B.6
-
112
-
-
0037093101
-
Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia
-
Van Der Kolk DM, Vellenga E, Scheffer GL, Muller M, Bates SE, Scheper RJ et al. (2002). Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia. Blood 99: 3763-3770.
-
(2002)
Blood
, vol.99
, pp. 3763-3770
-
-
Van Der Kolk, D.M.1
Vellenga, E.2
Scheffer, G.L.3
Muller, M.4
Bates, S.E.5
Scheper, R.J.6
-
113
-
-
30344444454
-
The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins
-
Van Herwaarden AE, Schinkel AH (2006). The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins. Trends Pharmacol Sci 27: 10-16.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 10-16
-
-
Van Herwaarden, A.E.1
Schinkel, A.H.2
-
114
-
-
0032565840
-
Solid phase synthesis of fumitremorgin, verruculogen and tryprostatin analogs based on a cyclization/cleavage strategy
-
Van Loevezijn A, Van Maarseveen JH, Stegman K, Visser GM, Koomen GJ (1998). Solid phase synthesis of fumitremorgin, verruculogen and tryprostatin analogs based on a cyclization/cleavage strategy. Tetrahedron Lett 39: 4737-4740.
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 4737-4740
-
-
Van Loevezijn, A.1
Van Maarseveen, J.H.2
Stegman, K.3
Visser, G.M.4
Koomen, G.J.5
-
115
-
-
0034212332
-
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism
-
Van Veen HW, Margolles A, Muller M, Higgins CF, Konings WN (2000). The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J 19: 2503-2514.
-
(2000)
EMBO J
, vol.19
, pp. 2503-2514
-
-
Van Veen, H.W.1
Margolles, A.2
Muller, M.3
Higgins, C.F.4
Konings, W.N.5
-
116
-
-
0034234294
-
Methotrexate cross-resistance in a mitoxantrone-selected multidrug-resistant MCF7 breast cancer cell line is attributable to enhanced energy-dependent drug efflux
-
Volk EL, Rohde K, Rhee M, McGuire JJ, Doyle LA, Ross DD et al. (2000). Methotrexate cross-resistance in a mitoxantrone-selected multidrug-resistant MCF7 breast cancer cell line is attributable to enhanced energy-dependent drug efflux. Cancer Res 60: 3514-3521.
-
(2000)
Cancer Res
, vol.60
, pp. 3514-3521
-
-
Volk, E.L.1
Rohde, K.2
Rhee, M.3
McGuire, J.J.4
Doyle, L.A.5
Ross, D.D.6
-
117
-
-
33646390931
-
Regulation of BCRP/ABCG2 expression by progesterone and 17β-estradiol in human placental BeWo cells
-
Wang H, Zhou L, Gupta A, Vethanayagam RR, Zhang Y, Unadkat JD et al. (2005). Regulation of BCRP/ABCG2 expression by progesterone and 17β-estradiol in human placental BeWo cells. Am J Physiol Endocrinol Metab 290: E798-E807.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Wang, H.1
Zhou, L.2
Gupta, A.3
Vethanayagam, R.R.4
Zhang, Y.5
Unadkat, J.D.6
-
118
-
-
2442520293
-
Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2
-
Xu J, Liu Y, Yang Y, Bates SE, Zhang J (2004). Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2. J Biol Chem 279: 19781-19789.
-
(2004)
J Biol Chem
, vol.279
, pp. 19781-19789
-
-
Xu, J.1
Liu, Y.2
Yang, Y.3
Bates, S.E.4
Zhang, J.5
-
119
-
-
4644329144
-
Gefitinib reverses breast cancer resistance protein-mediated drug resistance
-
Yanese K, Tsukahara S, Asada S, Ishikawa E, Imai Y, Sugimoto Y (2004). Gefitinib reverses breast cancer resistance protein-mediated drug resistance. Mol Cancer Ther 3: 1119-1125.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1119-1125
-
-
Yanese, K.1
Tsukahara, S.2
Asada, S.3
Ishikawa, E.4
Imai, Y.5
Sugimoto, Y.6
-
120
-
-
33644758036
-
Functional SNPs of the breast cancer resistance protein; therapeutic effects and inhibitor development
-
Yanese K, Tsukahara S, Mitsuhashi J, Sugimoto Y (2005). Functional SNPs of the breast cancer resistance protein; therapeutic effects and inhibitor development. Cancer Lett 234: 73-80.
-
(2005)
Cancer Lett
, vol.234
, pp. 73-80
-
-
Yanese, K.1
Tsukahara, S.2
Mitsuhashi, J.3
Sugimoto, Y.4
-
121
-
-
22144481699
-
Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein
-
Zhang S, Yang X, Coburn RA, Morris ME (2005). Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein. Biochem Pharmacol 70: 627-639.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 627-639
-
-
Zhang, S.1
Yang, X.2
Coburn, R.A.3
Morris, M.E.4
-
122
-
-
2142711101
-
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
-
Zhang S, Yang X, Morris ME (2004). Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Mol Pharmacol 65: 1208-1216.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 1208-1216
-
-
Zhang, S.1
Yang, X.2
Morris, M.E.3
-
123
-
-
0037125973
-
Bcrp1 gene expression is required for normal numbers of population stem cells in mice and confers relative protection to mitoxantrone in hematopoietic cells in vivo
-
Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD, Sorrentino BP (2002). Bcrp1 gene expression is required for normal numbers of population stem cells in mice and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc Natl Acad Sci USA 99: 12339-12344.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12339-12344
-
-
Zhou, S.1
Morris, J.J.2
Barnes, Y.3
Lan, L.4
Schuetz, J.D.5
Sorrentino, B.P.6
-
124
-
-
0034795256
-
The ABC transporter Bcrp1/Abcg2 is expressed in a variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ et al. (2001). The ABC transporter Bcrp1/Abcg2 is expressed in a variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7: 1028-1034.
-
(2001)
Nat Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
-
125
-
-
15244352173
-
Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels
-
Zhou S, Zong Y, Ney PA, Nair G, Stewart CF, Sorrentino BP (2005). Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels. Blood 105: 2571-2576.
-
(2005)
Blood
, vol.105
, pp. 2571-2576
-
-
Zhou, S.1
Zong, Y.2
Ney, P.A.3
Nair, G.4
Stewart, C.F.5
Sorrentino, B.P.6
|