Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2)

Biochemical Journal

Volumn 385, Issue 2, 2005, Pages 419-426

  Janvilisri, Tavan ^a   Shahi, Sanjay ^a   Venter, Henrietta ^a   Balakrishnan, Lekshmy ^a   Van Veen, Hendrik W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

ABCG2; Antibiotics; ATP binding cassette transporter (ABC transporter); Breast cancer resistance protein (BCRP); Lactococcus lactis; Primary bile acid; Unconjugated sterol

Indexed keywords

CELL CULTURE; DRUG PRODUCTS; ELECTROSTATICS; PH EFFECTS; POSITIVE IONS; PROTEINS;

ATP-BINDING CASSETTE (ABC); BREAST CANCER RESISTANCE PROTEIN (BCRP); PRIMARY BILE ACIDS; UNCONJUGATED STEROLS;

ANTIBIOTICS;

ABC TRANSPORTER; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; ARGININE; BILE ACID; BREAST CANCER RESISTANCE PROTEIN; CATION; CEFALOTIN; CHOLIC ACID; DEOXYCHOLIC ACID; DIRITHROMYCIN; ERYTHROMYCIN; GLYCOCHENODEOXYCHOLIC ACID; MEPACRINE; METHOTREXATE; OFLOXACIN; RHODAMINE 123; RIFAMPICIN; STEROL; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID; TETRACYCLINE; TETRAMETHYLROSAMINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE MUTATION; LACTOCOCCUS LACTIS; MAMMAL CELL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; PROTON TRANSPORT; WILD TYPE;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; ARGININE; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; ESTRADIOL; GENE EXPRESSION REGULATION; GLYCINE; HUMANS; LACTOCOCCUS LACTIS; METHOTREXATE; MUTATION, MISSENSE; NEOPLASM PROTEINS; RHODAMINE 123; STEROLS;

BACTERIA (MICROORGANISMS); EUKARYOTA; LACTOCOCCUS LACTIS; MAMMALIA; PROKARYOTA;

EID: 12844280511     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040791     Document Type: Article

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