-
1
-
-
3042643033
-
The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein
-
Allinson, T., Parkin, E., Turner, A.J. and Hooper, N.M. The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein. Eur. J. Biochem. 2004. 271: 2539-2547.
-
(2004)
Eur. J. Biochem
, vol.271
, pp. 2539-2547
-
-
Allinson, T.1
Parkin, E.2
Turner, A.J.3
Hooper, N.M.4
-
2
-
-
0037468588
-
Aging-related downregulation of neprilysin, a putative β-amyloid-degrading enzyme, in transgenic Tg2576 Alzheimer-like mouse brain is accompanied by an astroglial upregulation in the vicinity of β-amyloid plaques
-
Apelt, J., Ach, K. and Schliebs, R. Aging-related downregulation of neprilysin, a putative β-amyloid-degrading enzyme, in transgenic Tg2576 Alzheimer-like mouse brain is accompanied by an astroglial upregulation in the vicinity of β-amyloid plaques. Neurosci. Lett. 2003. 339: 183-186.
-
(2003)
Neurosci. Lett
, vol.339
, pp. 183-186
-
-
Apelt, J.1
Ach, K.2
Schliebs, R.3
-
3
-
-
0036177440
-
Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus
-
Arndt, J.W., Hao, B., Ramakrishnan, V., Cheng, T., Chan, S.I. and Chan, M.K. Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus. Structure. 2002. 10: 215-224.
-
(2002)
Structure
, vol.10
, pp. 215-224
-
-
Arndt, J.W.1
Hao, B.2
Ramakrishnan, V.3
Cheng, T.4
Chan, S.I.5
Chan, M.K.6
-
4
-
-
0035282893
-
Vasopeptidase inhibitors: An emerging class of cardiovascular drugs
-
Bralet, J. and Schwartz, J.-C. Vasopeptidase inhibitors: an emerging class of cardiovascular drugs. Trends Pharmacol. Sci. 2001. 22: 106-109.
-
(2001)
Trends Pharmacol. Sci
, vol.22
, pp. 106-109
-
-
Bralet, J.1
Schwartz, J.-C.2
-
5
-
-
33645100936
-
Neprilysin participates in skeletal muscle regeneration and is accumulated in abnormal muscle fibres of inclusion body myositis
-
Broccolini, A., Gidaro, T., Morosetti, R., Gliubizzi, C., Servidei, T., Pescatori, M., Tonali, P.A., Ricci, E. and Mirabella, M. Neprilysin participates in skeletal muscle regeneration and is accumulated in abnormal muscle fibres of inclusion body myositis. J. Neurochem. 2006. 96: 777-789.
-
(2006)
J. Neurochem
, vol.96
, pp. 777-789
-
-
Broccolini, A.1
Gidaro, T.2
Morosetti, R.3
Gliubizzi, C.4
Servidei, T.5
Pescatori, M.6
Tonali, P.A.7
Ricci, E.8
Mirabella, M.9
-
6
-
-
0026595567
-
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs
-
Burdick, D., Soreghan, B., Kwon, M., Kosmoski, J., Knauer, M., Henschen, A., Yates, J., Cotman, C. and Glabe, C. Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. J. Biol. Chem. 1992. 267: 546-554.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 546-554
-
-
Burdick, D.1
Soreghan, B.2
Kwon, M.3
Kosmoski, J.4
Knauer, M.5
Henschen, A.6
Yates, J.7
Cotman, C.8
Glabe, C.9
-
7
-
-
0035816661
-
A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao, X. and Sudhof, T.C. A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science. 2001. 293: 115-120.
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
8
-
-
0036794008
-
Declining expression of neprilysin in Alzheimer disease vasculature: Possible involvement in cerebral amyloid angiopathy
-
Carpentier, M., Robitaille, Y., DesGroseillers, L., Boileau, G. and Marcinkiewicz, M. Declining expression of neprilysin in Alzheimer disease vasculature: possible involvement in cerebral amyloid angiopathy. J. Neuropathol. Exp. Neurol. 2002. 61: 849-856.
-
(2002)
J. Neuropathol. Exp. Neurol
, vol.61
, pp. 849-856
-
-
Carpentier, M.1
Robitaille, Y.2
DesGroseillers, L.3
Boileau, G.4
Marcinkiewicz, M.5
-
9
-
-
0036077536
-
β-amyloid catabolism: Roles for neprilysin (NEP) and other metallopeptidases?
-
Carson, J.A. and Turner, A.J. β-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases? J. Neurochem. 2002. 81: 1-8.
-
(2002)
J. Neurochem
, vol.81
, pp. 1-8
-
-
Carson, J.A.1
Turner, A.J.2
-
10
-
-
33646369950
-
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity
-
Chen, F., Hasegawa, H., Schmitt-Ulms, G., Kawarai, T., Bohm, C., Katayama, T., Gu, Y, Sanjo, N., Glista, M., Rogaeva, E., Wakutani, Y., Pardossi-Piquard, R., Ruan, X., Tandon, A., Checler, F., Marambaud, P., Hansen, K., Westaway, D., St George-Hyslop, P. and Fraser, P. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 2006. 440: 1208-1212.
-
(2006)
Nature
, vol.440
, pp. 1208-1212
-
-
Chen, F.1
Hasegawa, H.2
Schmitt-Ulms, G.3
Kawarai, T.4
Bohm, C.5
Katayama, T.6
Gu, Y.7
Sanjo, N.8
Glista, M.9
Rogaeva, E.10
Wakutani, Y.11
Pardossi-Piquard, R.12
Ruan, X.13
Tandon, A.14
Checler, F.15
Marambaud, P.16
Hansen, K.17
Westaway, D.18
St George-Hyslop, P.19
Fraser, P.20
more..
-
11
-
-
33645299023
-
The involvement of lipid rafts in Alzheimer's disease
-
Cordy, J.M., Hooper, N.M., Turner, A.J. The involvement of lipid rafts in Alzheimer's disease. Mol. Membr. Biol. 2006. 23: 111-122.
-
(2006)
Mol. Membr. Biol
, vol.23
, pp. 111-122
-
-
Cordy, J.M.1
Hooper, N.M.2
Turner, A.J.3
-
12
-
-
0037142101
-
Angiotensin-converting enzyme 2 is an essential regulator of heart function
-
Crackower, M.A., Sarao, R., Oudit, G.Y., Yagil, C., Kozieradzki, I., Scanga, S.E., Oliveira-dos-Santos, A.J., da Costa, J., Zhang, L., Pei, Y., Scholey, J., Ferrario, C.M., Manoukian, A.S., Chappell, M.C., Backx, P.H., Yagil, Y. and Penninger, J.M. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002. 417: 799-802.
-
(2002)
Nature
, vol.417
, pp. 799-802
-
-
Crackower, M.A.1
Sarao, R.2
Oudit, G.Y.3
Yagil, C.4
Kozieradzki, I.5
Scanga, S.E.6
Oliveira-dos-Santos, A.J.7
da Costa, J.8
Zhang, L.9
Pei, Y.10
Scholey, J.11
Ferrario, C.M.12
Manoukian, A.S.13
Chappell, M.C.14
Backx, P.H.15
Yagil, Y.16
Penninger, J.M.17
-
13
-
-
0037048716
-
Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors
-
Dales, N.A., Gould, A.E., Brown, J.A., Calderwood, E.F., Guan, B., Minor, C.A., Gavin, J.M., Hales, P., Kaushik, V.K., Stewart, M., Tummino, P.J., Vickers, C.S., Ocain, T.D. and Patane, M.A. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J. Am. Chem. Soc. 2002. 124: 11852-11853.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 11852-11853
-
-
Dales, N.A.1
Gould, A.E.2
Brown, J.A.3
Calderwood, E.F.4
Guan, B.5
Minor, C.A.6
Gavin, J.M.7
Hales, P.8
Kaushik, V.K.9
Stewart, M.10
Tummino, P.J.11
Vickers, C.S.12
Ocain, T.D.13
Patane, M.A.14
-
14
-
-
2442529818
-
Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression
-
Dawson, L.A., Maitland, N.J., Turner, A.J., Usmani, B.A. Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression. Br. J. Cancer. 2004. 90: 1577-1582.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 1577-1582
-
-
Dawson, L.A.1
Maitland, N.J.2
Turner, A.J.3
Usmani, B.A.4
-
15
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
-
Donoghue, M., Hsieh, F., Baronas, E., Godbout, K., Gosselin, M., Stagliano, N., Donovan, M., Woolf, B., Robison, K., Jeyaseelan, R., Breitbart, R.E. and Acton, S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ. Res. 2000. 87: 1-9.
-
(2000)
Circ. Res
, vol.87
, pp. 1-9
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
Godbout, K.4
Gosselin, M.5
Stagliano, N.6
Donovan, M.7
Woolf, B.8
Robison, K.9
Jeyaseelan, R.10
Breitbart, R.E.11
Acton, S.12
-
16
-
-
0035816707
-
Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme
-
Eckman, E.A., Reed, D.K. and Eckman, C.B. Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme. J. Biol. Chem. 2001. 276: 24540-24548.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 24540-24548
-
-
Eckman, E.A.1
Reed, D.K.2
Eckman, C.B.3
-
17
-
-
0037462769
-
Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme
-
Eckman, E.A., Watson, M., Marlow, L., Sambamurti, K. and Eckman, C.B. Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. J. Biol. Chem. 2003. 278: 2081-2084.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 2081-2084
-
-
Eckman, E.A.1
Watson, M.2
Marlow, L.3
Sambamurti, K.4
Eckman, C.B.5
-
18
-
-
0037466757
-
Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: A comparison with neprilysin and endothelinconverting enzyme-1
-
Facchinetti, P., Rose, C., Schwartz, J.C., Ouimet, T. Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: a comparison with neprilysin and endothelinconverting enzyme-1. Neuroscience. 2003. 118: 627-639.
-
(2003)
Neuroscience
, vol.118
, pp. 627-639
-
-
Facchinetti, P.1
Rose, C.2
Schwartz, J.C.3
Ouimet, T.4
-
19
-
-
33744928081
-
Regulation of endothelin-converting enzyme-1 expression in human neuroblastoma cells
-
Fisk, L., Nalivaeva, N.N. and Turner, A.J. Regulation of endothelin-converting enzyme-1 expression in human neuroblastoma cells. Exp. Biol. Med. 2006. 231:1048-53.
-
(2006)
Exp. Biol. Med
, vol.231
, pp. 1048-1053
-
-
Fisk, L.1
Nalivaeva, N.N.2
Turner, A.J.3
-
21
-
-
18444417998
-
-
Francis, R., McGrath, G., Zhang, J., Ruddy, D.A., Sym, M., Apfeld, J., Nicoll, M., Maxwell, M., Hai, B., Ellis, M.C., Parks, A.L., Xu, W., Li, J., Gurney, M., Myers, R.L., Himes, C.S., Hiebsch, R., Ruble, C., Nye, J.S., Curtis, D. Aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev. Cell. 2002. 3: 85-97.
-
Francis, R., McGrath, G., Zhang, J., Ruddy, D.A., Sym, M., Apfeld, J., Nicoll, M., Maxwell, M., Hai, B., Ellis, M.C., Parks, A.L., Xu, W., Li, J., Gurney, M., Myers, R.L., Himes, C.S., Hiebsch, R., Ruble, C., Nye, J.S., Curtis, D. Aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev. Cell. 2002. 3: 85-97.
-
-
-
-
22
-
-
0242569193
-
Angiotensin-converting enzyme-2 (ACE2): Comparative modeling of the active site, specificity requirements, and chloride dependence
-
Guy, J.L., Jackson, R.M., Acharya, K.R., Sturrock, E.D., Hooper, N.M. and Turner, A.J. Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence. Biochemistry. 2003. 42: 13185-13192.
-
(2003)
Biochemistry
, vol.42
, pp. 13185-13192
-
-
Guy, J.L.1
Jackson, R.M.2
Acharya, K.R.3
Sturrock, E.D.4
Hooper, N.M.5
Turner, A.J.6
-
23
-
-
22544481731
-
Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis
-
Guy, J.L., Jackson, R.M., Jensen, H.A., Hooper, N.M. and Turner, A.J. Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis. FEBS J. 2005. 272: 3512-3520.
-
(2005)
FEBS J
, vol.272
, pp. 3512-3520
-
-
Guy, J.L.1
Jackson, R.M.2
Jensen, H.A.3
Hooper, N.M.4
Turner, A.J.5
-
24
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy, J.A. and Higgins, G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science. 1992. 256: 184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
25
-
-
27744587358
-
γ-secretase-independent mechanism of signal transduction by the amyloid precursor protein
-
Hass, M.R. and Yankner, B.A. A γ-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J. Biol. Chem. 2005. 280: 36895-36904.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 36895-36904
-
-
Hass, M.R.1
Yankner, B.A.A.2
-
26
-
-
33745584643
-
-
Hebert, S.S., Serneels, L., Tolia, A., Craessaerts, K., Derks, C., Filippov, M.A., Muller, U. and De Strooper, B. Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO Rep. 2006. May 19; [Epub ahead of print]
-
Hebert, S.S., Serneels, L., Tolia, A., Craessaerts, K., Derks, C., Filippov, M.A., Muller, U. and De Strooper, B. Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO Rep. 2006. May 19; [Epub ahead of print]
-
-
-
-
27
-
-
0038462074
-
-
Hersh, L.B., Yu, J., Zhu, H., Gao, J.T., Mucke, L. and Kindy, M.S. J. Neurochem. 2002. 81 (Suppl. 1): 67.
-
(2002)
J. Neurochem
, vol.81
, Issue.SUPPL. 1
, pp. 67
-
-
Hersh, L.B.1
Yu, J.2
Zhu, H.3
Gao, J.T.4
Mucke, L.5
Kindy, M.S.6
-
28
-
-
34247610570
-
Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction
-
Epub ahead of print, PMID: 16730806
-
Ho, T.Y., Wu, S.L., Chen, J.C., Li, C.C., Hsiang, C.Y. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction. Antiviral Res. 2006. [Epub ahead of print], PMID: 16730806.
-
(2006)
Antiviral Res
-
-
Ho, T.Y.1
Wu, S.L.2
Chen, J.C.3
Li, C.C.4
Hsiang, C.Y.5
-
31
-
-
0023431536
-
Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane
-
Hooper, N.M., Keen, J., Pappin, D.J.C. and Turner, A.J. Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane. Biochem. J. 1987. 247: 85-93.
-
(1987)
Biochem. J
, vol.247
, pp. 85-93
-
-
Hooper, N.M.1
Keen, J.2
Pappin, D.J.C.3
Turner, A.J.4
-
32
-
-
0027513914
-
Membrane peptidases on human osteoblast-like cells in culture: Hydrolysis of calcitonin and hormonal regulation of endopeptidase-24.11
-
Howell, S., Caswell, A.M., Kenny, A.J. and Turner, A.J. Membrane peptidases on human osteoblast-like cells in culture: hydrolysis of calcitonin and hormonal regulation of endopeptidase-24.11. Biochem. J. 1993. 290: 159-164.
-
(1993)
Biochem. J
, vol.290
, pp. 159-164
-
-
Howell, S.1
Caswell, A.M.2
Kenny, A.J.3
Turner, A.J.4
-
33
-
-
0037507256
-
Novel peptide inhibitors of angiotensin-converting enzyme 2
-
Huang, L., Sexton, D.J., Skogerson, K., Devlin, M., Smith, R., Sanyal, I., Parry, T., Kent, R., Enright, J., Wu, Q.-L., Conley, G., DeOliveira, D., Morganelli, L., Ducar, M., Wescott, C.R. and Ladner, R.C. Novel peptide inhibitors of angiotensin-converting enzyme 2. J. Biol. Chem. 2003. 278:15532-15540.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 15532-15540
-
-
Huang, L.1
Sexton, D.J.2
Skogerson, K.3
Devlin, M.4
Smith, R.5
Sanyal, I.6
Parry, T.7
Kent, R.8
Enright, J.9
Wu, Q.-L.10
Conley, G.11
DeOliveira, D.12
Morganelli, L.13
Ducar, M.14
Wescott, C.R.15
Ladner, R.C.16
-
34
-
-
21844460785
-
Angiotensin-converting enzyme 2 protects from severe acute lung failure
-
Imai, Y., Kuba, K., Rao, S., Huan, Y., Guo, F., Guan, B., Yang, P., Sarao, R., Wada, T., Leong-Poi, H., Crackower, M.A., Fukamizu, A., Hui, C.C., Hein, L., Uhlig, S., Slutsky, A.S. Jiang, C. and Penninger, J.M. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature. 2005. 436: 112-116.
-
(2005)
Nature
, vol.436
, pp. 112-116
-
-
Imai, Y.1
Kuba, K.2
Rao, S.3
Huan, Y.4
Guo, F.5
Guan, B.6
Yang, P.7
Sarao, R.8
Wada, T.9
Leong-Poi, H.10
Crackower, M.A.11
Fukamizu, A.12
Hui, C.C.13
Hein, L.14
Uhlig, S.15
Slutsky, A.S.16
Jiang, C.17
Penninger, J.M.18
-
35
-
-
0033621739
-
Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition
-
Iwata, N., Tsubuki, S., Takaki, Y., Watanabe, K., Seikiguchi, M., Hosoki, E., Kawashima-Morishima, M., Lee, H-J., Hama, E., Sekine-Aizawa, Y. and Saido, T.C. Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition. Nat. Med. 2000. 6: 143-150.
-
(2000)
Nat. Med
, vol.6
, pp. 143-150
-
-
Iwata, N.1
Tsubuki, S.2
Takaki, Y.3
Watanabe, K.4
Seikiguchi, M.5
Hosoki, E.6
Kawashima-Morishima, M.7
Lee, H.-J.8
Hama, E.9
Sekine-Aizawa, Y.10
Saido, T.C.11
-
36
-
-
14844327519
-
Prevalence and pathogenic role of cerebrovascular lesions in Alzheimer disease
-
Jellinger, K.A. and Attems, J. Prevalence and pathogenic role of cerebrovascular lesions in Alzheimer disease. J. Neurol. Sci. 2005. 229-230: 37-41.
-
(2005)
J. Neurol. Sci
, vol.229-230
, pp. 37-41
-
-
Jellinger, K.A.1
Attems, J.2
-
37
-
-
0024282457
-
Role of endopeptidase-24.11 in the inactivation of atrial natriuretic peptide
-
Kenny, A.J. and Stephenson, S.L. Role of endopeptidase-24.11 in the inactivation of atrial natriuretic peptide. FEBS Lett. 1988. 232: 1-8.
-
(1988)
FEBS Lett
, vol.232
, pp. 1-8
-
-
Kenny, A.J.1
Stephenson, S.L.2
-
38
-
-
0037434846
-
Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril
-
Kim, H.M., Shin, D.R., Yoo, O.J., Lee, H. and Lee, J.-O. Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril. FEBS Lett. 2003. 538: 65-70.
-
(2003)
FEBS Lett
, vol.538
, pp. 65-70
-
-
Kim, H.M.1
Shin, D.R.2
Yoo, O.J.3
Lee, H.4
Lee, J.-O.5
-
39
-
-
0025352441
-
Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception
-
Kumar, G.K., Runold, M., Ghai, R.D., Cherniack, N.S., Prabhakar, N.R. Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception. Brain Res. 1990. 517: 341-343.
-
(1990)
Brain Res
, vol.517
, pp. 341-343
-
-
Kumar, G.K.1
Runold, M.2
Ghai, R.D.3
Cherniack, N.S.4
Prabhakar, N.R.5
-
40
-
-
0034464347
-
Role of substance P in neutral endopeptidase modulation of hypoxic response of the carotid body
-
Kumar, G.K., Yu, R.K., Overholt, J.L. and Prabhakar, N.R. Role of substance P in neutral endopeptidase modulation of hypoxic response of the carotid body. Adv. Exp. Med. Biol. 2000. 475: 705-713.
-
(2000)
Adv. Exp. Med. Biol
, vol.475
, pp. 705-713
-
-
Kumar, G.K.1
Yu, R.K.2
Overholt, J.L.3
Prabhakar, N.R.4
-
41
-
-
24044444558
-
Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin converting enzyme-2 (ACE2)
-
Lambert, D.W., Yarski, M., Warner, F.J., Thornhill, P., Parkin, E.T., Smith, A.I., Hooper, N.M. and Turner AJ. Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin converting enzyme-2 (ACE2). J. Biol. Chem. 2005. 280: 30113-30119.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 30113-30119
-
-
Lambert, D.W.1
Yarski, M.2
Warner, F.J.3
Thornhill, P.4
Parkin, E.T.5
Smith, A.I.6
Hooper, N.M.7
Turner, A.J.8
-
42
-
-
0023796690
-
Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase
-
Letarte, M., Vera, S., Tran, R., Addis, J.B., Onizuka, R.J., Quackenbush, E.J., Jongeneel, C.V. and McInnes, R.R. Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase. J.. Exp. Med. 1988. 168: 1247-1253.
-
(1988)
J.. Exp. Med
, vol.168
, pp. 1247-1253
-
-
Letarte, M.1
Vera, S.2
Tran, R.3
Addis, J.B.4
Onizuka, R.J.5
Quackenbush, E.J.6
Jongeneel, C.V.7
McInnes, R.R.8
-
43
-
-
24944498409
-
Structure of SARS coronavirus spike receptor-binding domain complexed with receptor
-
Li, F., Li, W., Farzan, M. and Harrison, S.C. Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science. 2005. 309: 1864-1868.
-
(2005)
Science
, vol.309
, pp. 1864-1868
-
-
Li, F.1
Li, W.2
Farzan, M.3
Harrison, S.C.4
-
44
-
-
0344395657
-
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
-
Li, W., Moore, M.J., Vasilieva, N., Sui, J., Wong, S.K., Berne, M.A., Somasundaran, M., Sullivan, J.L., Luzuriaga, K., Greenough, T.C., Choe, H. and Farzan, M. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003. 426: 450-454.
-
(2003)
Nature
, vol.426
, pp. 450-454
-
-
Li, W.1
Moore, M.J.2
Vasilieva, N.3
Sui, J.4
Wong, S.K.5
Berne, M.A.6
Somasundaran, M.7
Sullivan, J.L.8
Luzuriaga, K.9
Greenough, T.C.10
Choe, H.11
Farzan, M.12
-
45
-
-
0037421496
-
No association between polymorphisms in the neprilysin promoter region and Swedish Alzheimer's disease patients
-
Lilius, L., Forsell, C., Axelman, K., Winblad, B., Graff, C. and Tjernberg, L. No association between polymorphisms in the neprilysin promoter region and Swedish Alzheimer's disease patients. Neurosci. Lett. 2003. 337, 111-113.
-
(2003)
Neurosci. Lett
, vol.337
, pp. 111-113
-
-
Lilius, L.1
Forsell, C.2
Axelman, K.3
Winblad, B.4
Graff, C.5
Tjernberg, L.6
-
46
-
-
0018073489
-
High-affinity enkephalin-degrading peptidase in brain is increased after morphine
-
Malfroy, B., Swerts, J.P., Guyon, A., Roques, B.P. and Schwartz, J.-C. High-affinity enkephalin-degrading peptidase in brain is increased after morphine. Nature. 1978. 276: 523-526.
-
(1978)
Nature
, vol.276
, pp. 523-526
-
-
Malfroy, B.1
Swerts, J.P.2
Guyon, A.3
Roques, B.P.4
Schwartz, J.-C.5
-
47
-
-
0037444432
-
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice
-
Marr, R.A., Rockenstein, E., Mukherjee, A., Kindy, M.S., Hersh, L.B., Gage, F.H., Verma, I.M., Masliah, E. Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. J. Neurosci. 2003. 23: 1992-1996.
-
(2003)
J. Neurosci
, vol.23
, pp. 1992-1996
-
-
Marr, R.A.1
Rockenstein, E.2
Mukherjee, A.3
Kindy, M.S.4
Hersh, L.B.5
Gage, F.H.6
Verma, I.M.7
Masliah, E.8
-
48
-
-
0010374240
-
Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli
-
Matsas, R., Fulcher, I.S., Kenny, A.J. and Turner, A.J. Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli. Proc. Natl. Acad. Sci. U.S.A. 1983. 80: 3111-3115.
-
(1983)
Proc. Natl. Acad. Sci. U.S.A
, vol.80
, pp. 3111-3115
-
-
Matsas, R.1
Fulcher, I.S.2
Kenny, A.J.3
Turner, A.J.4
-
49
-
-
0021211465
-
The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11
-
Matsas, R., Turner, A.J. and Kenny, A.J. The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11. Biochem. J. 1984. 223: 433-440.
-
(1984)
Biochem. J
, vol.223
, pp. 433-440
-
-
Matsas, R.1
Turner, A.J.2
Kenny, A.J.3
-
50
-
-
0037144078
-
Aβ42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo
-
Mohajeri, M.H., Wollmer, M.A. and Nitsch, R.M. Aβ42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo. J. Biol. Chem. 2002. 277: 35460-35465.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 35460-35465
-
-
Mohajeri, M.H.1
Wollmer, M.A.2
Nitsch, R.M.3
-
51
-
-
14944380978
-
Effect of hypoxia/ischemia and hypoxic preconditioning/reperfusion on expression of some amyloid-degrading enzymes
-
Nalivaeva, N.N., Fisk, L., Kochkina, E.G., Plesneva, S.A., Zhuravin, I.A., Babusikova, E., Dobrota, D., Turner, A.J. Effect of hypoxia/ischemia and hypoxic preconditioning/reperfusion on expression of some amyloid-degrading enzymes. Ann. N. Y. Acad. Sci. 2004. 1035: 21-33.
-
(2004)
Ann. N. Y. Acad. Sci
, vol.1035
, pp. 21-33
-
-
Nalivaeva, N.N.1
Fisk, L.2
Kochkina, E.G.3
Plesneva, S.A.4
Zhuravin, I.A.5
Babusikova, E.6
Dobrota, D.7
Turner, A.J.8
-
52
-
-
0346195665
-
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
-
Natesh, R., Schwager, S.L.U., Sturrock, E.D. and Acharya, K.R. Crystal structure of the human angiotensin-converting enzyme-lisinopril complex. Nature. 2003. 421: 551-554.
-
(2003)
Nature
, vol.421
, pp. 551-554
-
-
Natesh, R.1
Schwager, S.L.U.2
Sturrock, E.D.3
Acharya, K.R.4
-
53
-
-
0042889311
-
A new wrestler in the battle between alpha- and beta-secretases for cleavage of APP
-
Neve, R.L. A new wrestler in the battle between alpha- and beta-secretases for cleavage of APP. Trends Neurosci. 2003. 26: 461-463.
-
(2003)
Trends Neurosci
, vol.26
, pp. 461-463
-
-
Neve, R.L.1
-
54
-
-
0034681296
-
Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon
-
Oefner, C., D'Arcy, A., Nennig, M., Winkler, F.K. and Dale, G.E. Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon. J. Mol. Biol. 2000. 296: 341-349.
-
(2000)
J. Mol. Biol
, vol.296
, pp. 341-349
-
-
Oefner, C.1
D'Arcy, A.2
Nennig, M.3
Winkler, F.K.4
Dale, G.E.5
-
55
-
-
0031889217
-
Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression
-
Papandreou, C.N., Usmani, B., Geng, Y., Bogenrieder, T., Freeman, R., Wilk, S., Finstad, C.L., Reuter, V.E., Powell, C.T., Scheinberg, D., Magill, C., Scher, H.I., Albino, A.P. and Nanus, D.M. Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression. Nat. Med. 1998. 4: 50-57.
-
(1998)
Nat. Med
, vol.4
, pp. 50-57
-
-
Papandreou, C.N.1
Usmani, B.2
Geng, Y.3
Bogenrieder, T.4
Freeman, R.5
Wilk, S.6
Finstad, C.L.7
Reuter, V.E.8
Powell, C.T.9
Scheinberg, D.10
Magill, C.11
Scher, H.I.12
Albino, A.P.13
Nanus, D.M.14
-
56
-
-
33646117014
-
Neprilysin activity and expression are controlled by nicastrin
-
Pardossi-Piquard, R., Dunys, J., Yu, G., St George-Hyslop, P., Alves da Costa, C. and Checler, F. Neprilysin activity and expression are controlled by nicastrin. J. Neurochem. 2006. 97:1052-1056.
-
(2006)
J. Neurochem
, vol.97
, pp. 1052-1056
-
-
Pardossi-Piquard, R.1
Dunys, J.2
Yu, G.3
St George-Hyslop, P.4
Alves da Costa, C.5
Checler, F.6
-
57
-
-
20444398562
-
-
Pardossi-Piquard, R., Petit, A., Kawarai, T., Sunyach, C., Alves da Costa, C., Vincent, B., Ring, S., D'Adamio, L., Shen, J., Muller, U., St George Hyslop, P.and Checler, F. Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron. 2005. 46: 541-554.
-
Pardossi-Piquard, R., Petit, A., Kawarai, T., Sunyach, C., Alves da Costa, C., Vincent, B., Ring, S., D'Adamio, L., Shen, J., Muller, U., St George Hyslop, P.and Checler, F. Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron. 2005. 46: 541-554.
-
-
-
-
58
-
-
0034488295
-
Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor
-
Passer, B., Pellegrini, L., Russo, C., Siegel, R.M., Lenardo, M.J., Schettini, G., Bachmann, M., Tabaton, M. and D'Adamio, L. Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor. J. Alzheimers Dis. 2000. 2: 289-301.
-
(2000)
J. Alzheimers Dis
, vol.2
, pp. 289-301
-
-
Passer, B.1
Pellegrini, L.2
Russo, C.3
Siegel, R.M.4
Lenardo, M.J.5
Schettini, G.6
Bachmann, M.7
Tabaton, M.8
D'Adamio, L.9
-
59
-
-
0037803570
-
Human and mouse proteases: A comparative genomic approach
-
Puente, X.S., Sanchez, L.M., Overall, C.M. and Lopez-Otin, C. Human and mouse proteases: a comparative genomic approach. Nat. Rev. Genet. 2003. 4: 544-558.
-
(2003)
Nat. Rev. Genet
, vol.4
, pp. 544-558
-
-
Puente, X.S.1
Sanchez, L.M.2
Overall, C.M.3
Lopez-Otin, C.4
-
60
-
-
24944538873
-
Vasopeptidase inhibition for blood pressure control: Emerging experience
-
Quaschning, T. Vasopeptidase inhibition for blood pressure control: emerging experience. Curr. Pharm. Des. 2005. 11: 3293-3299.
-
(2005)
Curr. Pharm. Des
, vol.11
, pp. 3293-3299
-
-
Quaschning, T.1
-
61
-
-
84944039718
-
Intruduction: Metallopeptidases and their clans
-
Barrett, A.J, Rawlings, N.D. and Woessner, J.F, eds, Elsevier Academic Press, London
-
Rawlings, N.D. and Barrett, A.J . Intruduction: metallopeptidases and their clans. In: Handbook of Proteolytic Enzymes, Barrett, A.J., Rawlings, N.D. and Woessner, J.F. (eds), Elsevier Academic Press, London, 2004, pp. 231-268.
-
(2004)
Handbook of Proteolytic Enzymes
, pp. 231-268
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
63
-
-
0021007899
-
Purification of endopeptidase-24.11 ('enkephalinase') from pig brain by immunoadsorbent chromatography
-
Relton, J.M., Gee, N.S., Matsas, R., Turner, A.J. and Kenny, A.J. Purification of endopeptidase-24.11 ('enkephalinase') from pig brain by immunoadsorbent chromatography. Biochem. J. 1983. 215: 5195-23.
-
(1983)
Biochem. J
, vol.215
, pp. 5195-5123
-
-
Relton, J.M.1
Gee, N.S.2
Matsas, R.3
Turner, A.J.4
Kenny, A.J.5
-
64
-
-
0019258298
-
The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice
-
Roques, B.P., Fournié-Zaluski, M.-C., Soroca, E., Lecomte, J.-M., Malfroy, B., Llorens-Cortes, C. and Schwartz, J.-C. The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice. Nature. 1980. 288: 286-288.
-
(1980)
Nature
, vol.288
, pp. 286-288
-
-
Roques, B.P.1
Fournié-Zaluski, M.-C.2
Soroca, E.3
Lecomte, J.-M.4
Malfroy, B.5
Llorens-Cortes, C.6
Schwartz, J.-C.7
-
65
-
-
0034083879
-
Cellular localization of neprilysin in mouse bone tissue and putative role in hydrolysis of osteogenic peptides
-
Ruchon, A.F., Marcinkiewicz, M., Ellefsen, K., Basak, A., Aubin, J., Crine, P., Boileau, G. Cellular localization of neprilysin in mouse bone tissue and putative role in hydrolysis of osteogenic peptides. J. Bone Miner Res. 2000. 15: 1266-1274.
-
(2000)
J. Bone Miner Res
, vol.15
, pp. 1266-1274
-
-
Ruchon, A.F.1
Marcinkiewicz, M.2
Ellefsen, K.3
Basak, A.4
Aubin, J.5
Crine, P.6
Boileau, G.7
-
66
-
-
17644425569
-
Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation
-
Saito, T., Iwata, N., Tsubuki, S., Takaki, Y., Takano, J., Huang, S.M., Suemoto, T., Higuchi, M. and Saido, T.C. Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation. Nat. Med. 2005. 11: 434-439.
-
(2005)
Nat. Med
, vol.11
, pp. 434-439
-
-
Saito, T.1
Iwata, N.2
Tsubuki, S.3
Takaki, Y.4
Takano, J.5
Huang, S.M.6
Suemoto, T.7
Higuchi, M.8
Saido, T.C.9
-
67
-
-
0025777822
-
Neutral endopeptidase 24.11 in rat peripheral tissues: Comparative localization by 'ex vivo' and 'in vitro' autoradiography
-
Sales, N., Dutriez, I., Maziere, B., Ottaviani, M., Roques, B.P. Neutral endopeptidase 24.11 in rat peripheral tissues: comparative localization by 'ex vivo' and 'in vitro' autoradiography. Regul. Pept. 1991. 33: 209-222.
-
(1991)
Regul. Pept
, vol.33
, pp. 209-222
-
-
Sales, N.1
Dutriez, I.2
Maziere, B.3
Ottaviani, M.4
Roques, B.P.5
-
68
-
-
0038163054
-
The preparation and function of the hypertensin-converting enzyme
-
Skeggs, L.T., Kahn, J.R. and Shumway, N.P. J. The preparation and function of the hypertensin-converting enzyme. Exp. Med. 1956. 103: 295-299.
-
(1956)
Exp. Med
, vol.103
, pp. 295-299
-
-
Skeggs, L.T.1
Kahn, J.R.2
Shumway, N.P.J.3
-
69
-
-
0031054674
-
Brain infarction and the clinical expression of Alzheimer disease. The Nun Study
-
Snowdon, D.A., Greiner, L.H., Mortimer, J.A., Riley, K.P., Greiner, PA. and Markesbery, W.R. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA. 1997. 277: 813-817.
-
(1997)
JAMA
, vol.277
, pp. 813-817
-
-
Snowdon, D.A.1
Greiner, L.H.2
Mortimer, J.A.3
Riley, K.P.4
Greiner, P.A.5
Markesbery, W.R.6
-
70
-
-
14844300150
-
Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function
-
Thomas, J.E., Rylett, C.M., Carhan, A., Bland, N.D., Bingham, R.J., Shirras, A.D., Turner, A.J. and Isaac, R.E. Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function. Biochem. J. 2005. 386: 357-366.
-
(2005)
Biochem. J
, vol.386
, pp. 357-366
-
-
Thomas, J.E.1
Rylett, C.M.2
Carhan, A.3
Bland, N.D.4
Bingham, R.J.5
Shirras, A.D.6
Turner, A.J.7
Isaac, R.E.8
-
71
-
-
33745263255
-
Soluble amyloid precursor protein α reduces neuronal injury and improves functional outcome following diffuse traumatic brain injury in rats
-
May 12; [Epub ahead of print
-
Thornton, E., Vink, R,. Blumbergs, P.C. and Van Den Heuvel, C. Soluble amyloid precursor protein α reduces neuronal injury and improves functional outcome following diffuse traumatic brain injury in rats. Brain Res. 2006. May 12; [Epub ahead of print].
-
(2006)
Brain Res
-
-
Thornton, E.1
Vink, R.2
Blumbergs, P.C.3
Van Den Heuvel, C.4
-
72
-
-
0037341501
-
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy
-
Tikellis, C., Johnston, C.I., Forbes, J.M., Burns, W.C., Burrell, L.M., Risvanis, J. and Cooper, M.E. Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy. Hypertension. 2004. 41: 392-397.
-
(2004)
Hypertension
, vol.41
, pp. 392-397
-
-
Tikellis, C.1
Johnston, C.I.2
Forbes, J.M.3
Burns, W.C.4
Burrell, L.M.5
Risvanis, J.6
Cooper, M.E.7
-
73
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
Tipnis, S.R., Hooper, N.M., Hyde, R., Karran, E., Christie, G. and Turner, A.J. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J. Biol. Chem. 2000. 275: 33238-33243.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turner, A.J.6
-
74
-
-
2342418543
-
ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis
-
Towler, P., Staker, B., Prasad, S.G., Menon, S., Tang, J., Parsons, T., Ryan, D., Fisher, M., Williams, D., Dales, N.A., Patane, M.A. and Pantoliano, M.W.. ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis. J. Biol. Chem. 2004. 279: 17996-18007.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 17996-18007
-
-
Towler, P.1
Staker, B.2
Prasad, S.G.3
Menon, S.4
Tang, J.5
Parsons, T.6
Ryan, D.7
Fisher, M.8
Williams, D.9
Dales, N.A.10
Patane, M.A.11
Pantoliano, M.W.12
-
75
-
-
0024422377
-
-
Tran-Paterson, R., Willard, H.F. and Letarte, M. The common acute lymphoblastic leukemia antigen (neutral endopeptidase-3.4.24.11) gene is located on human chromosome 3. Cancer Genet. Cytogenet. 1989. 42: 129-134.
-
Tran-Paterson, R., Willard, H.F. and Letarte, M. The common acute lymphoblastic leukemia antigen (neutral endopeptidase-3.4.24.11) gene is located on human chromosome 3. Cancer Genet. Cytogenet. 1989. 42: 129-134.
-
-
-
-
76
-
-
0036535405
-
The angiotensin-converting enzyme gene family: Genomics and pharmacology
-
Turner, A.J. and Hooper, N.M. The angiotensin-converting enzyme gene family: genomics and pharmacology. Trends Pharmacol. Sci. 2002. 23: 177-183.
-
(2002)
Trends Pharmacol. Sci
, vol.23
, pp. 177-183
-
-
Turner, A.J.1
Hooper, N.M.2
-
77
-
-
0030899822
-
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX
-
Turner, A.J. and Tanzawa, K. Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX. FASEB J. 1997. 11: 355-364.
-
(1997)
FASEB J
, vol.11
, pp. 355-364
-
-
Turner, A.J.1
Tanzawa, K.2
-
78
-
-
14944344493
-
Targeting amyloid-degrading enzymes as therapeutic strategies in neurodegeneration
-
Turner, A.J., Fisk, L. and Nalivaeva, N. N. Targeting amyloid-degrading enzymes as therapeutic strategies in neurodegeneration. Ann. N. Y. Acad. Sci. 2004. 1035: 1-20.
-
(2004)
Ann. N. Y. Acad. Sci
, vol.1035
, pp. 1-20
-
-
Turner, A.J.1
Fisk, L.2
Nalivaeva, N.N.3
-
79
-
-
0035112440
-
The neprilysin (NEP) family of zinc metalloendopeptidases: Genomics and function
-
Turner, A.J., Isaac, R.E. and Coates, D. The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function. Bioessays. 2001. 23: 261-269.
-
(2001)
Bioessays
, vol.23
, pp. 261-269
-
-
Turner, A.J.1
Isaac, R.E.2
Coates, D.3
-
80
-
-
0042634362
-
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
-
Turner, P.R., O'Connor, K., Tate, W.P. and Abraham, W.C. Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog. Neurobiol. 2003. 70: 1-32.
-
(2003)
Prog. Neurobiol
, vol.70
, pp. 1-32
-
-
Turner, P.R.1
O'Connor, K.2
Tate, W.P.3
Abraham, W.C.4
-
81
-
-
0036671726
-
Differential expression of neutral endopeptidase-24.11 (neprilysin) and endothelin-converting enzyme in human prostate cancer cell lines
-
Usmani, B.A., Harden, B., Maitland, N.J. and Turner, A.J. Differential expression of neutral endopeptidase-24.11 (neprilysin) and endothelin-converting enzyme in human prostate cancer cell lines. Clin. Sci. (Lond). 2002. 103 (Suppl 48): 314S-317S.
-
(2002)
Clin. Sci. (Lond)
, vol.103
, Issue.SUPPL. 48
-
-
Usmani, B.A.1
Harden, B.2
Maitland, N.J.3
Turner, A.J.4
-
82
-
-
0033623415
-
Aβ-generating enzymes: Recent advances in β- and γ-secretase research
-
Vassar, R. and Citron M. Aβ-generating enzymes: recent advances in β- and γ-secretase research. Neuron. 2000, 27: 419-422.
-
(2000)
Neuron
, vol.27
, pp. 419-422
-
-
Vassar, R.1
Citron, M.2
-
83
-
-
18544378161
-
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
-
Vickers, C., Hales, P., Kaushik, V., Dick, L., Gavin, J., Tang, J., Godbout, K., Parsons, T., Baronas, E., Hsieh, F., Acton, S., Patane, M., Nichols, A. and Tummino, P. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J. Biol. Chem. 2002. 277: 14838-14843.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 14838-14843
-
-
Vickers, C.1
Hales, P.2
Kaushik, V.3
Dick, L.4
Gavin, J.5
Tang, J.6
Godbout, K.7
Parsons, T.8
Baronas, E.9
Hsieh, F.10
Acton, S.11
Patane, M.12
Nichols, A.13
Tummino, P.14
-
84
-
-
2142815707
-
-
Wen, Y., Onyewuchi, O., Yang, S., Liu, R., Simpkins, J.W. Increased β-secretase activity and expression in rats following transient cerebral ischemia. Brain Res. 2004. 1009: 1-8.
-
Wen, Y., Onyewuchi, O., Yang, S., Liu, R., Simpkins, J.W. Increased β-secretase activity and expression in rats following transient cerebral ischemia. Brain Res. 2004. 1009: 1-8.
-
-
-
-
85
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
-
Wolfe, M.S., Xia, W., Ostaszewski, B.L., Diehl, T.S., Kimberly, W.T. and Selkoe, D.J. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity. Nature. 1999. 398: 513-517.
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
86
-
-
0035846826
-
Reduced neprilysin in high plaque areas of Alzheimer brain: A possible relationship to deficient degradation of β-amyloid peptide
-
Yasojima, K., Akiyama, H., McGeer, E.G. and McGeer, P.L. Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of β-amyloid peptide. Neurosci. Lett. 2001. 297: 97-100.
-
(2001)
Neurosci. Lett
, vol.297
, pp. 97-100
-
-
Yasojima, K.1
Akiyama, H.2
McGeer, E.G.3
McGeer, P.L.4
-
87
-
-
0034618715
-
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
-
Yu, G., Nishimura, M., Arawaka, S., Levitan, D., Zhang, L., Tandon, A., Song, Y.Q., Rogaeva, E., Chen, F., Kawarai, T., Supala, A., Levesque, L., Yu, H., Yang, D.S., Holmes, E., Milman, P., Liang, Y., Zhang, D.M., Xu, D.H., Sato, C., Rogaev, E., Smith, M., Janus, C., Zhang, Y., Aebersold, R., Farrer, L.S., Sorbi, S., Bruni, A., Fraser, P., St George-Hyslop, P. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 2000, 407: 48-54.
-
(2000)
Nature
, vol.407
, pp. 48-54
-
-
Yu, G.1
Nishimura, M.2
Arawaka, S.3
Levitan, D.4
Zhang, L.5
Tandon, A.6
Song, Y.Q.7
Rogaeva, E.8
Chen, F.9
Kawarai, T.10
Supala, A.11
Levesque, L.12
Yu, H.13
Yang, D.S.14
Holmes, E.15
Milman, P.16
Liang, Y.17
Zhang, D.M.18
Xu, D.H.19
Sato, C.20
Rogaev, E.21
Smith, M.22
Janus, C.23
Zhang, Y.24
Aebersold, R.25
Farrer, L.S.26
Sorbi, S.27
Bruni, A.28
Fraser, P.29
St George-Hyslop, P.30
more..
-
88
-
-
0035907347
-
Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys
-
Zhang, H., Wada, J., Hida, K., Tsuchiyama, Y., Hiragushi, K., Shikata, K., Wang, H., Lin, S., Kanwar, Y.S. and Makino, H. Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys. J. Biol. Chem. 2001. 276: 17132-17139.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 17132-17139
-
-
Zhang, H.1
Wada, J.2
Hida, K.3
Tsuchiyama, Y.4
Hiragushi, K.5
Shikata, K.6
Wang, H.7
Lin, S.8
Kanwar, Y.S.9
Makino, H.10
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