Reduced neprilysin in high plaque areas of Alzheimer brain: A possible relationship to deficient degradation of β-amyloid peptide

Neuroscience Letters

Volumn 297, Issue 2, 2001, Pages 97-100

  Yasojima, Koji ^a   Akiyama, Haruhiko ^b   McGeer, Edith G ^a   McGeer, Patrick L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

CD10; Common acute lymphoblastic leukemia antigen; Enkephalinase; Hippocampus; Microtubule associated protein 2; mRNA; Reverse transcription polymerase chain reaction; Western blots

Indexed keywords

AMYLOID BETA PROTEIN; MEMBRANE METALLOENDOPEPTIDASE; MESSENGER RNA;

ADULT; ALZHEIMER DISEASE; ARTICLE; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SENILE PLAQUE; TEMPORAL CORTEX;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BLOTTING, WESTERN; BRAIN; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEPRILYSIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENILE PLAQUES;

EID: 0035846826     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01675-X     Document Type: Article

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