Angiotensin-Converting Enzyme-2 (ACE2): Comparative Modeling of the Active Site, Specificity Requirements, and Chloride Dependence

Biochemistry

Volumn 42, Issue 45, 2003, Pages 13185-13192

  Guy, Jodie L ^a   Jackson, Richard M ^a   Acharya, K Ravi ^b   Sturrock, Edward D ^c   Hooper, Nigel M ^a   Turner, Anthony J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b University of Bath   (United Kingdom)

^c SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIO-RENAL DISEASES;

CARDIOLOGY; CRYSTAL STRUCTURE; DISEASES; HYDROLYSIS; HYDROPHOBICITY;

ENZYMES;

ANGIOTENSIN; CARBOXYPEPTIDASE; CHLORIDE; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SPECIFICITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; BINDING SITES; CARBOXYPEPTIDASES; CHLORIDES; CHO CELLS; CRICETINAE; HUMANS; HYDROLYSIS; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDYL-DIPEPTIDASE A; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHLORIDE; SUBSTRATE SPECIFICITY; TESTIS;

ANIMALIA;

EID: 0242569193     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035268s     Document Type: Article

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