메뉴 건너뛰기




Volumn 23, Issue 4, 2002, Pages 177-183

The angiotensin-converting enzyme gene family: Genomics and pharmacology

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN I; BRADYKININ; CAPTOPRIL; CERANAPRIL; CILAZAPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ENALAPRILAT; G PROTEIN COUPLED RECEPTOR; METALLOPROTEINASE; RAMIPRIL;

EID: 0036535405     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01994-5     Document Type: Review
Times cited : (362)

References (66)
  • 2
    • 0037834636 scopus 로고    scopus 로고
    • Angiotensin receptors: Distribution, signalling and function
    • (2001) Clin. Sci. , vol.100 , pp. 481-492
    • Dinh, D.T.1
  • 4
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensin converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • (2000) J. Biol. Chem. , vol.275 , pp. 33238-33243
    • Tipnis, S.R.1
  • 5
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    • (2000) Circ. Res. , vol.87
    • Donoghue, M.1
  • 6
    • 0038163054 scopus 로고
    • The preparation and function of the hypertensin-converting enzyme
    • (1956) J. Exp. Med. , vol.103 , pp. 295-299
    • Skeggs, L.T.1
  • 8
    • 1842292171 scopus 로고    scopus 로고
    • The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice
    • (1997) J. Clin. Invest. , vol.99 , pp. 2375-2385
    • Esther, C.R.1
  • 9
    • 0023431536 scopus 로고
    • Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane
    • (1987) Biochem. J. , vol.247 , pp. 85-93
    • Hooper, N.M.1
  • 10
    • 0027247370 scopus 로고
    • Characterization of a secretase activity which releases angiotensin-converting enzyme from the membrane
    • (1993) Biochem. J. , vol.292 , pp. 597-603
    • Oppong, S.Y.1    Hooper, N.M.2
  • 15
    • 0042908657 scopus 로고
    • Molecular cloning of human testicular angiotensin-converting enzyme: The testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 7741-7745
    • Ehlers, M.R.W.1
  • 16
    • 0025824349 scopus 로고
    • Structure of the angiotensin I converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene
    • (1991) J. Biol. Chem. , vol.266 , pp. 15377-15383
    • Hubert, C.1
  • 17
    • 0027175193 scopus 로고
    • Differences in properties and enzymatic specificities between the two active sites of angiotensin I-converting enzyme. Studies with bradykinin and other natural peptides
    • (1993) J. Biol. Chem. , vol.268 , pp. 9496-9503
    • Jaspard, E.1
  • 18
    • 0028967315 scopus 로고
    • The haemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme
    • (1995) J. Biol. Chem. , vol.270 , pp. 3656-3661
    • Rousseau, A.1
  • 19
    • 0035823581 scopus 로고    scopus 로고
    • 1098 is critical for the chloride dependence of human angiotensin I-converting enzyme C-domain catalytic activity
    • (2001) J. Biol. Chem. , vol.276 , pp. 33518-33525
    • Liu, X.1
  • 20
    • 0026643458 scopus 로고
    • The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors
    • (1992) J. Biol. Chem. , vol.267 , pp. 13398-13405
    • Wei, L.1
  • 21
    • 0027051423 scopus 로고
    • Two binding-sites on angiotensin-converting enzyme: Evidence from radioligand binding studies
    • (1992) Mol. Pharmacol. , vol.42 , pp. 286-293
    • Perich, R.B.1
  • 22
    • 0030659835 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer
    • (1997) Biochem. J. , vol.327 , pp. 37-43
    • Parvathy, S.1
  • 23
    • 0032502033 scopus 로고    scopus 로고
    • Alzheimer's amyloid precursor protein α-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: Similarities to the angiotensin converting enzyme secretase
    • (1998) Biochemistry , vol.37 , pp. 1680-1685
    • Parvathy, S.1
  • 25
    • 8044257704 scopus 로고    scopus 로고
    • A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
    • (1997) Nature , vol.385 , pp. 729-733
    • Black, R.A.1
  • 26
    • 8044250278 scopus 로고    scopus 로고
    • Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
    • (1997) Nature , vol.385 , pp. 733-736
    • Moss, M.L.1
  • 28
    • 0032503959 scopus 로고    scopus 로고
    • The secretases that cleave angiotensin converting enzyme and the amyloid precursor protein are distinct from tumour necrosis factor-α convertase
    • (1998) FEBS Lett. , vol.431 , pp. 63-65
    • Parvathy, S.1
  • 29
    • 0033537888 scopus 로고    scopus 로고
    • Unaltered cleavage and secretion of angiotensin-converting enzyme in tumor-necrosis factor-α-converting enzyme-deficient mice
    • (1999) J. Biol. Chem. , vol.274 , pp. 10511-10516
    • Sadhukhan, R.1
  • 30
  • 31
    • 0034194191 scopus 로고    scopus 로고
    • Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites
    • (2000) Biochem. J. , vol.347 , pp. 711-718
    • Woodman, Z.L.1
  • 34
    • 0027970068 scopus 로고
    • Identification of two active site residues in human angiotensin I-converting enzyme
    • (1994) J. Biol. Chem. , vol.269 , pp. 29430-29434
    • Williams, T.A.1
  • 35
    • 0034615567 scopus 로고    scopus 로고
    • Metallocarboxypeptidases and their protein inhibitors. Structure, function and biomedical properties
    • (2000) Biochim. Biophys. Acta , vol.1477 , pp. 284-298
    • Vendrell, J.1
  • 36
    • 85006100126 scopus 로고
    • Carboxypeptidase Taq, a thermostable zinc enzyme, from Thermus aquaticus YT-1: Molecular cloning, sequencing, and expression of the encoding gene in Escherichia coli
    • (1994) Biosci. Biotechnol. Biochem. , vol.58 , pp. 1490-1495
    • Lee, S.-H.1
  • 38
    • 0036179768 scopus 로고    scopus 로고
    • Radioligand binding reveals chymase as the predominant enzyme for mediating tissue conversion of angiotensin I in the normal human heart
    • (2002) Clin. Sci. , vol.102 , pp. 15-21
    • Katugampola, S.D.1    Davenport, A.P.2
  • 41
  • 42
    • 0035016194 scopus 로고    scopus 로고
    • A role for the angiotensin IV/AT4 system in mediating natriuresis in the rat
    • (2001) Peptides , vol.22 , pp. 935-944
    • Hamilton, T.A.1
  • 44
    • 0030921136 scopus 로고    scopus 로고
    • The globin fragment LVV-hemorphin-7 is an endogenous ligand for the AT4 receptor in the brain
    • (1997) J. Neurochem. , vol.68 , pp. 2530-2537
    • Moeller, I.1
  • 45
    • 0032820247 scopus 로고    scopus 로고
    • Angiotensin-(1-7) is a modulator of the human renin-angiotensin system
    • (1999) Hypertension , vol.34 , pp. 296-301
    • Roks, A.J.1
  • 46
    • 0026073830 scopus 로고
    • Angiotensin-(1-7): A member of circulating angiotensin peptides
    • (1991) Hypertension , vol.17 , pp. 131-138
    • Kohara, K.1
  • 48
    • 0033822806 scopus 로고    scopus 로고
    • Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats
    • (2000) Hypertension , vol.36 , pp. 417-422
    • Iyer, S.N.1
  • 50
    • 0035050698 scopus 로고    scopus 로고
    • Angiotensin-(1-7) does not affect vasodilator or TPA responses to bradykinin in human forearm
    • (2001) Hypertension , vol.37 , pp. 1136-1140
    • Wilsdorf, T.1
  • 51
    • 0023727622 scopus 로고
    • Formation of angiotensin-II and other angiotensin peptides from [des-Leu-10]-angiotensin-I in rat lung and kidney
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 4327-4333
    • Drummer, O.H.1
  • 52
    • 0031954590 scopus 로고    scopus 로고
    • N-domain specific substrate and C-domain inhibitors of angiotensin converting enzyme
    • (1998) Hypertension , vol.31 , pp. 912-917
    • Deddish, P.A.1
  • 53
    • 0035955732 scopus 로고    scopus 로고
    • The angiotensin II AT2 receptor is an AT1 receptor antagonist
    • (2001) J. Biol. Chem. , vol.276 , pp. 39721-39726
    • Abdalla, S.1
  • 55
    • 0023117452 scopus 로고
    • Purification and characterization of a peptidyl dipeptidase resembling angiotensin converting enzyme from the electric organ of Torpedo marmorata
    • (1987) J. Neurochem. , vol.48 , pp. 910-916
    • Turner, A.J.1
  • 56
    • 0033387605 scopus 로고    scopus 로고
    • Insect angiotensin-converting enzyme - A processing enzyme with broad substrate specificity and a role in reproduction
    • (1999) Ann. New York Acad. Sci. , vol.897 , pp. 342-347
    • Isaac, R.E.1
  • 57
    • 0032520023 scopus 로고    scopus 로고
    • A novel peptide-processing activity of insect peptidyl-dipeptidase A (angiotensin I-converting enzyme): The hydrolysis of lysyl-arginine and arginyl-arginine from the C-terminus of an insect prohormone peptide
    • (1998) Biochem. J. , vol.330 , pp. 61-65
    • Isaac, R.E.1
  • 58
    • 0033153238 scopus 로고    scopus 로고
    • Hydrolysis by somatic angiotensin-I converting enzyme of basic dipeptides from a cholecystokinin/gastrin and a LH-RH peptide extended at the C-terminus with Gly-Arg/Lys-Arg, but not from diarginyl insulin
    • (1999) Eur. J. Biochem. , vol.262 , pp. 569-574
    • Isaac, R.E.1
  • 59
    • 0029008621 scopus 로고
    • Cloning and expression of an evolutionary conserved single-domain angiotensin-converting enzyme from Drosophila melanogaster
    • (1995) J. Biol. Chem. , vol.270 , pp. 13613-13619
    • Cornel, M.J.1
  • 60
    • 0000049249 scopus 로고    scopus 로고
    • The Acer gene of Drosophila codes for an angiotensin-converting enzyme homologue
    • (1996) Gene , vol.181 , pp. 191-197
    • Taylor, C.A.M.1
  • 61
    • 0032213594 scopus 로고    scopus 로고
    • The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance - Distinct enzymic characteristics and alternative expression during pupal development
    • (1998) Eur. J. Biochem. , vol.257 , pp. 599-606
    • Houard, X.1
  • 62
    • 0034254520 scopus 로고    scopus 로고
    • Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme
    • (2000) Biochemistry , vol.39 , pp. 8963-8969
    • Coates, D.1
  • 63
    • 0033850610 scopus 로고    scopus 로고
    • Exploring the Caenorhabditis elegans and Drosophila melanogaster genomes to understand neuropeptide and peptidase function
    • (2000) Biochem. Soc. Trans. , vol.28 , pp. 464-469
    • Coates, D.1
  • 65
    • 0035907347 scopus 로고    scopus 로고
    • Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys
    • (2001) J. Biol. Chem. , vol.276 , pp. 17132-17139
    • Zhang, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.