-
1
-
-
0006443304
-
Hemostasis in the mouse (Mus musculus): A review
-
Tsakiris DA, Scudder L, Hodivala-Dilke K, Hynes RO, Coller BS. Hemostasis in the mouse (Mus musculus): A review. Thromb Haemost 1999; 81: 177-88.
-
(1999)
Thromb Haemost
, vol.81
, pp. 177-188
-
-
Tsakiris, D.A.1
Scudder, L.2
Hodivala-Dilke, K.3
Hynes, R.O.4
Coller, B.S.5
-
2
-
-
0141745002
-
Large-scale, high-throughput screening for coagulation and hematological phenotypes in mice
-
Peters LL, Cheever EM, Ellis HR, Magnani PA, Svenson KL, von Smith R, Bogue MA. Large-scale, high-throughput screening for coagulation and hematological phenotypes in mice. Physiol Genomics 2002; 11: 185-93.
-
(2002)
Physiol Genomics
, vol.11
, pp. 185-193
-
-
Peters, L.L.1
Cheever, E.M.2
Ellis, H.R.3
Magnani, P.A.4
Svenson, K.L.5
von Smith, R.6
Bogue, M.A.7
-
3
-
-
0021669789
-
Species specificity of tissue thromboplastin
-
Janson TL, Stormorken H, Prydz H. Species specificity of tissue thromboplastin. Haemostasis 1984; 14: 440-4.
-
(1984)
Haemostasis
, vol.14
, pp. 440-444
-
-
Janson, T.L.1
Stormorken, H.2
Prydz, H.3
-
4
-
-
0029906976
-
Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3
-
Holmbach K, Danton MJ, Suh TT, Daugherty CC, Degen JL. Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3. EMBO J 1996; 15: 5760-71.
-
(1996)
EMBO J
, vol.15
, pp. 5760-5771
-
-
Holmbach, K.1
Danton, M.J.2
Suh, T.T.3
Daugherty, C.C.4
Degen, J.L.5
-
5
-
-
0034762541
-
A hamster antibody to the mouse fibrinogen gamma chain inhibits platelet-fibrinogen interactions and FXIIIa-mediated fibrin cross-linking, and facilitates thrombolysis
-
Jirouskova M, Smyth SS, Kudryk B, Coller BS. A hamster antibody to the mouse fibrinogen gamma chain inhibits platelet-fibrinogen interactions and FXIIIa-mediated fibrin cross-linking, and facilitates thrombolysis. Thromb Haemost 2001; 86: 1047-56.
-
(2001)
Thromb Haemost
, vol.86
, pp. 1047-1056
-
-
Jirouskova, M.1
Smyth, S.S.2
Kudryk, B.3
Coller, B.S.4
-
6
-
-
85047691114
-
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo
-
Flick MJ, Du X, Witte DP, Jirouskova M, Soloviev DA, Busuttil SJ, Plow EF, Degen JL. Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo. J Clin Invest 2004; 113: 1596-606.
-
(2004)
J Clin Invest
, vol.113
, pp. 1596-1606
-
-
Flick, M.J.1
Du, X.2
Witte, D.P.3
Jirouskova, M.4
Soloviev, D.A.5
Busuttil, S.J.6
Plow, E.F.7
Degen, J.L.8
-
9
-
-
10744231546
-
Cause-effect relation between hyperfibrinogenemia and vascular disease
-
Kerlin B, Cooley BC, Isermann BH, Hernandez I, Sood R, Zogg M, Hendrickson SB, Mosesson MW, Lord S, Weiler H. Cause-effect relation between hyperfibrinogenemia and vascular disease. Blood 2004; 103: 1728-34.
-
(2004)
Blood
, vol.103
, pp. 1728-1734
-
-
Kerlin, B.1
Cooley, B.C.2
Isermann, B.H.3
Hernandez, I.4
Sood, R.5
Zogg, M.6
Hendrickson, S.B.7
Mosesson, M.W.8
Lord, S.9
Weiler, H.10
-
10
-
-
0035572892
-
Characterization of a mouse model for thrombomodulin deficiency
-
Weiler H, Lindner V, Kerlin B, Isermann BH, Hendrickson SB, Cooley BC, Meh DA, Mosesson MW, Shworak NW, Post MJ, Conway EM, Ulfman LH, von Andrian UH, Weitz JI. Characterization of a mouse model for thrombomodulin deficiency. Arterioscler Thromb Vasc Biol 2001; 21: 1531-7.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1531-1537
-
-
Weiler, H.1
Lindner, V.2
Kerlin, B.3
Isermann, B.H.4
Hendrickson, S.B.5
Cooley, B.C.6
Meh, D.A.7
Mosesson, M.W.8
Shworak, N.W.9
Post, M.J.10
Conway, E.M.11
Ulfman, L.H.12
von Andrian, U.H.13
Weitz, J.I.14
-
11
-
-
0032080409
-
A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state
-
Weiler-Guettler H, Christie PD, Beeler DL, Healy AM, Hancock WW, Rayburn H, Edelberg JM, Rosenberg RD. A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state. J Clin Invest 1998; 101: 1983-91.
-
(1998)
J Clin Invest
, vol.101
, pp. 1983-1991
-
-
Weiler-Guettler, H.1
Christie, P.D.2
Beeler, D.L.3
Healy, A.M.4
Hancock, W.W.5
Rayburn, H.6
Edelberg, J.M.7
Rosenberg, R.D.8
-
12
-
-
0035883064
-
Variable protection of beta 3-integrin-deficient mice from thrombosis initiated by different mechanisms
-
Smyth SS, Reis ED, Vaananen H, Zhang W, Coller BS. Variable protection of beta 3-integrin-deficient mice from thrombosis initiated by different mechanisms. Blood 2001; 98: 1055-62.
-
(2001)
Blood
, vol.98
, pp. 1055-1062
-
-
Smyth, S.S.1
Reis, E.D.2
Vaananen, H.3
Zhang, W.4
Coller, B.S.5
-
13
-
-
0033941427
-
Monoclonal antibody designated T2G1 reacts with human fibrin beta-chain but not with the corresponding chain from mouse fibrin
-
Kudryk BJ, Bini A. Monoclonal antibody designated T2G1 reacts with human fibrin beta-chain but not with the corresponding chain from mouse fibrin. Arterioscler Thromb Vasc Biol 2000; 20: 1848-9.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1848-1849
-
-
Kudryk, B.J.1
Bini, A.2
-
14
-
-
0036799775
-
Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse
-
Falati S, Gross P, Merrill-Skoloff G, Furie BC, Furie B. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nat Med 2002; 8: 1175-81.
-
(2002)
Nat Med
, vol.8
, pp. 1175-1181
-
-
Falati, S.1
Gross, P.2
Merrill-Skoloff, G.3
Furie, B.C.4
Furie, B.5
-
15
-
-
0033562859
-
Structure-function analyses of thrombomodulin by gene-targeting in mice: The cytoplasmic domain is not required for normal fetal development
-
Conway EM, Pollefeyt S, Cornelissen J, DeBaere I, Steiner-Mosonyi M, Weitz JI, Weiler-Guettler H, Carmeliet P, Collen D. Structure-function analyses of thrombomodulin by gene-targeting in mice: The cytoplasmic domain is not required for normal fetal development. Blood 1999; 93: 3442-50.
-
(1999)
Blood
, vol.93
, pp. 3442-3450
-
-
Conway, E.M.1
Pollefeyt, S.2
Cornelissen, J.3
DeBaere, I.4
Steiner-Mosonyi, M.5
Weitz, J.I.6
Weiler-Guettler, H.7
Carmeliet, P.8
Collen, D.9
-
16
-
-
0032560579
-
Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice
-
Xue J, Wu Q, Westfield LA, Tuley EA, Lu D, Zhang Q, Shim K, Zheng X, Sadler JE. Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice. Proc Natl Acad Sci USA 1998; 95: 7603-7.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7603-7607
-
-
Xue, J.1
Wu, Q.2
Westfield, L.A.3
Tuley, E.A.4
Lu, D.5
Zhang, Q.6
Shim, K.7
Zheng, X.8
Sadler, J.E.9
-
17
-
-
0032560553
-
Prothrombin deficiency results in embryonic and neonatal lethality in mice
-
Sun WY, Witte DP, Degen JL, Colbert MC, Burkart MC, Holmback K, Xiao Q, Bugge TH, Degen SJ. Prothrombin deficiency results in embryonic and neonatal lethality in mice. Proc Natl Acad Sci USA 1998; 95: 7597-602.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7597-7602
-
-
Sun, W.Y.1
Witte, D.P.2
Degen, J.L.3
Colbert, M.C.4
Burkart, M.C.5
Holmback, K.6
Xiao, Q.7
Bugge, T.H.8
Degen, S.J.9
-
18
-
-
0035659180
-
Influence of the genetic background on platelet function, microparticle and thrombin generation in the common laboratory mouse
-
Zumbach A, Marbet GA, Tsakiris DA. Influence of the genetic background on platelet function, microparticle and thrombin generation in the common laboratory mouse. Platelets 2001; 12: 496-502.
-
(2001)
Platelets
, vol.12
, pp. 496-502
-
-
Zumbach, A.1
Marbet, G.A.2
Tsakiris, D.A.3
-
20
-
-
0347597765
-
Combined deficiency of protease-activated receptor-4 and fibrinogen recapitulates the hemostatic defect but not the embryonic lethality of prothrombin deficiency
-
Camerer E, Duong DN, Hamilton JR, Coughlin SR. Combined deficiency of protease-activated receptor-4 and fibrinogen recapitulates the hemostatic defect but not the embryonic lethality of prothrombin deficiency. Blood 2004; 103: 152-4.
-
(2004)
Blood
, vol.103
, pp. 152-154
-
-
Camerer, E.1
Duong, D.N.2
Hamilton, J.R.3
Coughlin, S.R.4
-
21
-
-
0034921205
-
Protease-activated receptors in vascular biology
-
Coughlin SR. Protease-activated receptors in vascular biology. Thromb Haemost 2001; 86: 298-307.
-
(2001)
Thromb Haemost
, vol.86
, pp. 298-307
-
-
Coughlin, S.R.1
-
22
-
-
0029868041
-
Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein
-
Kounnas MZ, Church FC, Argraves WS, Strickland DK. Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein. J Biol Chem 1996; 271: 6523-9.
-
(1996)
J Biol Chem
, vol.271
, pp. 6523-6529
-
-
Kounnas, M.Z.1
Church, F.C.2
Argraves, W.S.3
Strickland, D.K.4
-
23
-
-
0033807066
-
Complete antithrombin deficiency in mice results in embryonic lethality
-
Ishiguro K, Kojima T, Kadomatsu K, Nakayama Y, Takagi A, Suzuki M, Takeda N, Ito M, Yamamoto K, Matsushita T, Kusugami K, Muramatsu T, Saito H. Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest 2000; 106: 873-8.
-
(2000)
J Clin Invest
, vol.106
, pp. 873-878
-
-
Ishiguro, K.1
Kojima, T.2
Kadomatsu, K.3
Nakayama, Y.4
Takagi, A.5
Suzuki, M.6
Takeda, N.7
Ito, M.8
Yamamoto, K.9
Matsushita, T.10
Kusugami, K.11
Muramatsu, T.12
Saito, H.13
-
24
-
-
10744227151
-
Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin
-
Dewerchin M, Herault JP, Wallays G, Petitou M, Schaeffer P, Millet L, Weitz JI, Moons L, Collen D, Carmeliet P, Herbert JM. Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin. Circ Res 2003; 93: 1120-6.
-
(2003)
Circ Res
, vol.93
, pp. 1120-1126
-
-
Dewerchin, M.1
Herault, J.P.2
Wallays, G.3
Petitou, M.4
Schaeffer, P.5
Millet, L.6
Weitz, J.I.7
Moons, L.8
Collen, D.9
Carmeliet, P.10
Herbert, J.M.11
-
25
-
-
4143096123
-
Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice
-
Aihara K, Azuma H, Akaike M, Ikeda Y, Yamashita M, Sudo T, Hayashi H, Yamada Y, Endoh F, Fujimura M, Yoshida T, Yamaguchi H, Hashizume S, Kato M, Yoshimura K, Yamamoto Y, Kato S, Matsumoto T. Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice. J Biol Chem 2004; 279: 35798-802.
-
(2004)
J Biol Chem
, vol.279
, pp. 35798-35802
-
-
Aihara, K.1
Azuma, H.2
Akaike, M.3
Ikeda, Y.4
Yamashita, M.5
Sudo, T.6
Hayashi, H.7
Yamada, Y.8
Endoh, F.9
Fujimura, M.10
Yoshida, T.11
Yamaguchi, H.12
Hashizume, S.13
Kato, M.14
Yoshimura, K.15
Yamamoto, Y.16
Kato, S.17
Matsumoto, T.18
-
26
-
-
0036155992
-
Heparin cofactor II inhibits arterial thrombosis after endothelial injury
-
He L, Vicente CP, Westrick RJ, Eitzman DT, Tollefsen DM. Heparin cofactor II inhibits arterial thrombosis after endothelial injury. J Clin Invest 2002; 109: 213-9.
-
(2002)
J Clin Invest
, vol.109
, pp. 213-219
-
-
He, L.1
Vicente, C.P.2
Westrick, R.J.3
Eitzman, D.T.4
Tollefsen, D.M.5
-
27
-
-
10244232835
-
Antithrombotic activity of dermatan sulfate in heparin cofactor II-deficient mice
-
Vicente CP, He L, Pavao MS, Tollefsen DM. Antithrombotic activity of dermatan sulfate in heparin cofactor II-deficient mice. Blood 2004; 104: 3965-70.
-
(2004)
Blood
, vol.104
, pp. 3965-3970
-
-
Vicente, C.P.1
He, L.2
Pavao, M.S.3
Tollefsen, D.M.4
-
28
-
-
0141889319
-
The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis
-
Sun H, Yang TL, Yang A, Wang X, Ginsburg D. The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood 2003; 102: 2856-61.
-
(2003)
Blood
, vol.102
, pp. 2856-2861
-
-
Sun, H.1
Yang, T.L.2
Yang, A.3
Wang, X.4
Ginsburg, D.5
-
29
-
-
0141889317
-
Biosynthetic origin and functional significance of murine platelet factor V
-
Yang TL, Pipe SW, Yang A, Ginsburg D. Biosynthetic origin and functional significance of murine platelet factor V. Blood 2003; 102: 2851-5.
-
(2003)
Blood
, vol.102
, pp. 2851-2855
-
-
Yang, T.L.1
Pipe, S.W.2
Yang, A.3
Ginsburg, D.4
-
30
-
-
0029854371
-
Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V
-
Cui J, O'Shea KS, Purkayastha A, Saunders TL, Ginsburg D. Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V. Nature 1996; 384: 66-8.
-
(1996)
Nature
, vol.384
, pp. 66-68
-
-
Cui, J.1
O'Shea, K.S.2
Purkayastha, A.3
Saunders, T.L.4
Ginsburg, D.5
-
31
-
-
0034672363
-
Spontaneous thrombosis in mice carrying the factor V Leiden mutation
-
Cui J, Eitzman DT, Westrick RJ, Christie PD, Xu ZJ, Yang AY, Purkayastha AA, Yang TL, Metz AL, Gallagher KP, Tyson JA, Rosenberg RD, Ginsburg D. Spontaneous thrombosis in mice carrying the factor V Leiden mutation. Blood 2000; 96: 4222-6.
-
(2000)
Blood
, vol.96
, pp. 4222-4226
-
-
Cui, J.1
Eitzman, D.T.2
Westrick, R.J.3
Christie, P.D.4
Xu, Z.J.5
Yang, A.Y.6
Purkayastha, A.A.7
Yang, T.L.8
Metz, A.L.9
Gallagher, K.P.10
Tyson, J.A.11
Rosenberg, R.D.12
Ginsburg, D.13
-
32
-
-
0142245617
-
Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia
-
Kerlin BA, Yan SB, Isermann BH, Brandt JT, Sood R, Basson BR, Joyce DE, Weiler H, Dhainaut JF. Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia. Blood 2003; 102: 3085-92.
-
(2003)
Blood
, vol.102
, pp. 3085-3092
-
-
Kerlin, B.A.1
Yan, S.B.2
Isermann, B.H.3
Brandt, J.T.4
Sood, R.5
Basson, B.R.6
Joyce, D.E.7
Weiler, H.8
Dhainaut, J.F.9
-
33
-
-
2142818618
-
Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII
-
Margaritis P, Arruda VR, Aljamali M, Camire RM, Schlachterman A, High KA. Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII. J Clin Invest 2004; 113: 1025-31.
-
(2004)
J Clin Invest
, vol.113
, pp. 1025-1031
-
-
Margaritis, P.1
Arruda, V.R.2
Aljamali, M.3
Camire, R.M.4
Schlachterman, A.5
High, K.A.6
-
34
-
-
0035955744
-
Elevated function of blood clotting factor VIIa mutants that have enhanced affinity for membranes. Behavior in a diffusion-limited reaction
-
Nelsestuen GL, Stone M, Martinez MB, Harvey SB, Foster D, Kisiel W. Elevated function of blood clotting factor VIIa mutants that have enhanced affinity for membranes. Behavior in a diffusion-limited reaction. J Biol Chem 2001; 276: 39825-31.
-
(2001)
J Biol Chem
, vol.276
, pp. 39825-39831
-
-
Nelsestuen, G.L.1
Stone, M.2
Martinez, M.B.3
Harvey, S.B.4
Foster, D.5
Kisiel, W.6
-
35
-
-
0030775316
-
Mice lacking factor VII develop normally but suffer fatal perinatal bleeding
-
Rosen ED, Chan JC, Idusogie E, Clotman F, Vlasuk G, Luther T, Jalbert J, Albrecht S, Zhong L, Lissens A, Schoojans L, Moons L, Collen D, Castellino FJ, Carmeliet P. Mice lacking factor VII develop normally but suffer fatal perinatal bleeding. Nature 1997; 390: 290-4.
-
(1997)
Nature
, vol.390
, pp. 290-294
-
-
Rosen, E.D.1
Chan, J.C.2
Idusogie, E.3
Clotman, F.4
Vlasuk, G.5
Luther, T.6
Jalbert, J.7
Albrecht, S.8
Zhong, L.9
Lissens, A.10
Schoojans, L.11
Moons, L.12
Collen, D.13
Castellino, F.J.14
Carmeliet, P.15
-
36
-
-
0033557184
-
Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit
-
Chan JC, Carmeliet P, Moons L, Rosen ED, Huang ZF, Broze Jr GJ, Collen D, Castellino FJ. Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit. J Clin Invest 1999; 103: 475-82.
-
(1999)
J Clin Invest
, vol.103
, pp. 475-482
-
-
Chan, J.C.1
Carmeliet, P.2
Moons, L.3
Rosen, E.D.4
Huang, Z.F.5
Broze, G.J.6
Collen, D.7
Castellino, F.J.8
-
37
-
-
0029011723
-
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A
-
Bi L, Lawler AM, Antonarakis SE, High KA, Gearhart JD, Kazazian Jr HH. Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. Nat Genetics 1995; 10: 119-21.
-
(1995)
Nat Genetics
, vol.10
, pp. 119-121
-
-
Bi, L.1
Lawler, A.M.2
Antonarakis, S.E.3
High, K.A.4
Gearhart, J.D.5
Kazazian, H.H.6
-
38
-
-
0032827192
-
Phenotypic expression of murine hemophilia
-
Muchitsch EM, Turecek PL, Zimmermann K, Pichler L, Auer W, Richter G, Gritsch H, Schwarz HP. Phenotypic expression of murine hemophilia. Thromb Haemost 1999; 82: 1371-3.
-
(1999)
Thromb Haemost
, vol.82
, pp. 1371-1373
-
-
Muchitsch, E.M.1
Turecek, P.L.2
Zimmermann, K.3
Pichler, L.4
Auer, W.5
Richter, G.6
Gritsch, H.7
Schwarz, H.P.8
-
39
-
-
0037926885
-
Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency
-
Bovenschen N, Herz J, Grimbergen JM, Lenting PJ, Havekes LM, Mertens K, van Vlijmen JM. Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency. Blood 2003; 101: 3933-9.
-
(2003)
Blood
, vol.101
, pp. 3933-3939
-
-
Bovenschen, N.1
Herz, J.2
Grimbergen, J.M.3
Lenting, P.J.4
Havekes, L.M.5
Mertens, K.6
van Vlijmen, J.M.7
-
40
-
-
0029163527
-
Age-specific regulation of clotting factor IX gene expression in normal and transgenic mice
-
Boland EJ, Liu YC, Walter CA, Herbert DC, Weaker FJ, Odom MW, Jagadeeswaran P. Age-specific regulation of clotting factor IX gene expression in normal and transgenic mice. Blood 1995; 86: 2198-205.
-
(1995)
Blood
, vol.86
, pp. 2198-2205
-
-
Boland, E.J.1
Liu, Y.C.2
Walter, C.A.3
Herbert, D.C.4
Weaker, F.J.5
Odom, M.W.6
Jagadeeswaran, P.7
-
41
-
-
4444335080
-
Creation of a mouse expressing defective human factor IX
-
Jin DY, Zhang TP, Gui T, Stafford DW, Monahan PE. Creation of a mouse expressing defective human factor IX. Blood 2004; 104: 1733-9.
-
(2004)
Blood
, vol.104
, pp. 1733-1739
-
-
Jin, D.Y.1
Zhang, T.P.2
Gui, T.3
Stafford, D.W.4
Monahan, P.E.5
-
42
-
-
7244231207
-
Novel hemophilia B mouse models exhibiting a range of mutations in the Factor IX gene
-
Sabatino DE, Armstrong E, Edmonson S, Liu YL, Pleimes M, Schuettrumpf J, Fitzgerald J, Herzog RW, Arruda VR, High KA. Novel hemophilia B mouse models exhibiting a range of mutations in the Factor IX gene. Blood 2004; 104: 2767-74.
-
(2004)
Blood
, vol.104
, pp. 2767-2774
-
-
Sabatino, D.E.1
Armstrong, E.2
Edmonson, S.3
Liu, Y.L.4
Pleimes, M.5
Schuettrumpf, J.6
Fitzgerald, J.7
Herzog, R.W.8
Arruda, V.R.9
High, K.A.10
-
43
-
-
0031878846
-
Cloning and characterization of a cDNA encoding murine coagulation factor X
-
Liang Z, Cooper A, DeFord ME, Carmeliet P, Collen D, Castellino FJ, Rosen ED. Cloning and characterization of a cDNA encoding murine coagulation factor X. Thromb Haemost 1998; 80: 87-91.
-
(1998)
Thromb Haemost
, vol.80
, pp. 87-91
-
-
Liang, Z.1
Cooper, A.2
DeFord, M.E.3
Carmeliet, P.4
Collen, D.5
Castellino, F.J.6
Rosen, E.D.7
-
44
-
-
0033950264
-
Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice
-
Dewerchin M, Liang Z, Moons L, Carmeliet P, Castellino FJ, Collen D, Rosen ED. Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice. Thromb Haemost 2000; 83: 185-90.
-
(2000)
Thromb Haemost
, vol.83
, pp. 185-190
-
-
Dewerchin, M.1
Liang, Z.2
Moons, L.3
Carmeliet, P.4
Castellino, F.J.5
Collen, D.6
Rosen, E.D.7
-
45
-
-
0037891818
-
In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses
-
Rosen ED, Cornelissen I, Liang Z, Zollman A, Casad M, Roahrig J, Suckow M, Castellino FJ. In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses. J Thromb Haemost 2003; 1: 19-27.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 19-27
-
-
Rosen, E.D.1
Cornelissen, I.2
Liang, Z.3
Zollman, A.4
Casad, M.5
Roahrig, J.6
Suckow, M.7
Castellino, F.J.8
-
46
-
-
0036918577
-
Targeted inactivation of the mouse locus encoding factor XIII-A: Hemostatic abnormalities in mutant mice and characterization of the coagulation deficit
-
Lauer P, Metzner HJ, Zettlmeissl G, Li M, Smith AG, Lathe R, Dickneite G. Targeted inactivation of the mouse locus encoding factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit. Thromb Haemost 2002; 88: 967-74.
-
(2002)
Thromb Haemost
, vol.88
, pp. 967-974
-
-
Lauer, P.1
Metzner, H.J.2
Zettlmeissl, G.3
Li, M.4
Smith, A.G.5
Lathe, R.6
Dickneite, G.7
-
47
-
-
0344305481
-
Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages
-
Koseki-Kuno S, Yamakawa M, Dickneite G, Ichinose A. Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages. Blood 2003; 102: 4410-2.
-
(2003)
Blood
, vol.102
, pp. 4410-4412
-
-
Koseki-Kuno, S.1
Yamakawa, M.2
Dickneite, G.3
Ichinose, A.4
-
48
-
-
0033534406
-
Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase
-
Mohlke KL, Purkayastha AA, Westrick RJ, Smith PL, Petryniak B, Lowe JB, Ginsburg D. Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell 1999; 96: 111-20.
-
(1999)
Cell
, vol.96
, pp. 111-120
-
-
Mohlke, K.L.1
Purkayastha, A.A.2
Westrick, R.J.3
Smith, P.L.4
Petryniak, B.5
Lowe, J.B.6
Ginsburg, D.7
-
49
-
-
0030447890
-
A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11
-
Mohlke KL, Nichols WC, Westrick RJ, Novak EK, Cooney KA, Swank RT, Ginsburg D. A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11. Proc Natl Acad Sci USA 1996; 93: 15352-7.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15352-15357
-
-
Mohlke, K.L.1
Nichols, W.C.2
Westrick, R.J.3
Novak, E.K.4
Cooney, K.A.5
Swank, R.T.6
Ginsburg, D.7
-
50
-
-
0032483024
-
A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis
-
Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Cullere M, Hynes RO, Wagner DD. A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis. Proc Natl Acad Sci USA 1998; 95: 9524-9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9524-9529
-
-
Denis, C.1
Methia, N.2
Frenette, P.S.3
Rayburn, H.4
Ullman-Cullere, M.5
Hynes, R.O.6
Wagner, D.D.7
-
51
-
-
0029853017
-
Activation of factor X by factor VIIa complexed with human-mouse tissue factor chimeras requires human exon 3
-
Fang CH, Lin TC, Guha A, Nemerson Y, Konigsberg WH. Activation of factor X by factor VIIa complexed with human-mouse tissue factor chimeras requires human exon 3. Thromb Haemost 1996; 76: 361-8.
-
(1996)
Thromb Haemost
, vol.76
, pp. 361-368
-
-
Fang, C.H.1
Lin, T.C.2
Guha, A.3
Nemerson, Y.4
Konigsberg, W.H.5
-
52
-
-
4544292323
-
Mouse models in haemostasis and thrombosis
-
Mackman N. Mouse models in haemostasis and thrombosis. Thromb Haemost 2004; 92: 440-3.
-
(2004)
Thromb Haemost
, vol.92
, pp. 440-443
-
-
Mackman, N.1
-
53
-
-
9544227474
-
Role of tissue factor in embryonic blood vessel development
-
Carmeliet P, Mackman N, Moons L, Luther T, Gressens P, Van Vlaenderen I, Demunck H, Kasper M, Breier G, Evrard P, Muller M, Risau W, Edgington T, Collen D. Role of tissue factor in embryonic blood vessel development. Nature 1996; 383: 73-5.
-
(1996)
Nature
, vol.383
, pp. 73-75
-
-
Carmeliet, P.1
Mackman, N.2
Moons, L.3
Luther, T.4
Gressens, P.5
Van Vlaenderen, I.6
Demunck, H.7
Kasper, M.8
Breier, G.9
Evrard, P.10
Muller, M.11
Risau, W.12
Edgington, T.13
Collen, D.14
-
54
-
-
0032006548
-
Low levels of tissue factor are compatible with development and hemostasis in mice
-
Parry GC, Erlich JH, Carmeliet P, Luther T, Mackman N. Low levels of tissue factor are compatible with development and hemostasis in mice. J Clin Invest 1998; 101: 560-9.
-
(1998)
J Clin Invest
, vol.101
, pp. 560-569
-
-
Parry, G.C.1
Erlich, J.H.2
Carmeliet, P.3
Luther, T.4
Mackman, N.5
-
55
-
-
15944383386
-
A balance between tissue factor and tissue factor pathway inhibitor is required for embryonic development and hemostasis in adult mice
-
Pedersen B, Holscher T, Sato Y, Pawlinski R, Mackman N. A balance between tissue factor and tissue factor pathway inhibitor is required for embryonic development and hemostasis in adult mice. Blood 2005; 105: 2777-82.
-
(2005)
Blood
, vol.105
, pp. 2777-2782
-
-
Pedersen, B.1
Holscher, T.2
Sato, Y.3
Pawlinski, R.4
Mackman, N.5
-
56
-
-
0032587854
-
TFPIbeta, a second product from the mouse tissue factor pathway inhibitor (TFPI) gene
-
Chang JY, Monroe DM, Oliver JA, Roberts HR. TFPIbeta, a second product from the mouse tissue factor pathway inhibitor (TFPI) gene. Thromb Haemost 1999; 81: 45-9.
-
(1999)
Thromb Haemost
, vol.81
, pp. 45-49
-
-
Chang, J.Y.1
Monroe, D.M.2
Oliver, J.A.3
Roberts, H.R.4
-
57
-
-
14644397985
-
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity
-
Pinotti M, Bertolucci C, Portaluppi F, Colognesi I, Frigato E, Foa A, Bernardi F. Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity. Arterioscler Thromb Vasc Biol 2005; 25: 646-9.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 646-649
-
-
Pinotti, M.1
Bertolucci, C.2
Portaluppi, F.3
Colognesi, I.4
Frigato, E.5
Foa, A.6
Bernardi, F.7
-
58
-
-
33646360216
-
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1
-
Zheng PS, Reis M, Sparling C, Lee DY, La Pierre DP, Wong CK, Deng Z, Kahai S, Wen J, Yang BB. Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. J Biol Chem 2006; 281: 8175-82.
-
(2006)
J Biol Chem
, vol.281
, pp. 8175-8182
-
-
Zheng, P.S.1
Reis, M.2
Sparling, C.3
Lee, D.Y.4
La Pierre, D.P.5
Wong, C.K.6
Deng, Z.7
Kahai, S.8
Wen, J.9
Yang, B.B.10
-
59
-
-
0030738021
-
Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice
-
Huang ZF, Higuchi D, Lasky N, Broze Jr GJ. Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice. Blood 1997; 90: 944-51.
-
(1997)
Blood
, vol.90
, pp. 944-951
-
-
Huang, Z.F.1
Higuchi, D.2
Lasky, N.3
Broze Jr., G.J.4
-
60
-
-
0037035484
-
Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden
-
Eitzman DT, Westrick RJ, Bi X, Manning SL, Wilkinson JE, Broze GJ, Ginsburg D. Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden. Circulation 2002; 105: 2139-42.
-
(2002)
Circulation
, vol.105
, pp. 2139-2142
-
-
Eitzman, D.T.1
Westrick, R.J.2
Bi, X.3
Manning, S.L.4
Wilkinson, J.E.5
Broze, G.J.6
Ginsburg, D.7
-
61
-
-
0035954299
-
Deficiency of tissue factor pathway inhibitor promotes atherosclerosis and thrombosis in mice
-
Westrick RJ, Bodary PF, Xu Z, Shen YC, Broze GJ, Eitzman DT. Deficiency of tissue factor pathway inhibitor promotes atherosclerosis and thrombosis in mice. Circulation 2001; 103: 3044-6.
-
(2001)
Circulation
, vol.103
, pp. 3044-3046
-
-
Westrick, R.J.1
Bodary, P.F.2
Xu, Z.3
Shen, Y.C.4
Broze, G.J.5
Eitzman, D.T.6
-
63
-
-
0034892611
-
Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis
-
Isermann B, Hendrickson SB, Zogg M, Wing M, Cummiskey M, Kisanuki YY, Yanagisawa M, Weiler H. Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis. J Clin Invest 2001; 108: 537-46.
-
(2001)
J Clin Invest
, vol.108
, pp. 537-546
-
-
Isermann, B.1
Hendrickson, S.B.2
Zogg, M.3
Wing, M.4
Cummiskey, M.5
Kisanuki, Y.Y.6
Yanagisawa, M.7
Weiler, H.8
-
64
-
-
0028876697
-
Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
-
Healy AM, Rayburn HB, Rosenberg RD, Weiler H. Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system. Proc Natl Acad Sci USA 1995; 92: 850-4.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 850-854
-
-
Healy, A.M.1
Rayburn, H.B.2
Rosenberg, R.D.3
Weiler, H.4
-
65
-
-
0037349926
-
The thrombomodulin-protein C system is essential for the maintenance of pregnancy
-
Isermann B, Snood R, Pawlinski R, Zoog M, Kalloway S, Degen JL, Mackman N, Weiler H. The thrombomodulin-protein C system is essential for the maintenance of pregnancy. Nat Med 2003; 9: 331-7.
-
(2003)
Nat Med
, vol.9
, pp. 331-337
-
-
Isermann, B.1
Snood, R.2
Pawlinski, R.3
Zoog, M.4
Kalloway, S.5
Degen, J.L.6
Mackman, N.7
Weiler, H.8
-
66
-
-
0032824727
-
Regulation of murine protein C gene expression in vivo: Effects of tumor necrosis factor-alpha, interleukin-1 and transforming growth factor-beta
-
Yamamoto K, Shimokawa T, Kojima T, Loskutoff DJ, Saito H. Regulation of murine protein C gene expression in vivo: Effects of tumor necrosis factor-alpha, interleukin-1 and transforming growth factor-beta. Thromb Haemost 1999; 82: 1297-301.
-
(1999)
Thromb Haemost
, vol.82
, pp. 1297-1301
-
-
Yamamoto, K.1
Shimokawa, T.2
Kojima, T.3
Loskutoff, D.J.4
Saito, H.5
-
67
-
-
17944396396
-
Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model
-
Fernández JA, Xu X, Liu D, Zlokovic BV, Griffin JH. Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model. Blood Cells Mol Dis 2003; 30: 271-6.
-
(2003)
Blood Cells Mol Dis
, vol.30
, pp. 271-276
-
-
Fernández, J.A.1
Xu, X.2
Liu, D.3
Zlokovic, B.V.4
Griffin, J.H.5
-
68
-
-
0025354415
-
Anti-protein C monoclonal antibody induces thrombus in mice
-
Kurosawa-Ohsawa K, Kimura M, Kume-Iwaki A, Tanaka T, Tanaka S. Anti-protein C monoclonal antibody induces thrombus in mice. Blood 1990; 75: 2156-63.
-
(1990)
Blood
, vol.75
, pp. 2156-2163
-
-
Kurosawa-Ohsawa, K.1
Kimura, M.2
Kume-Iwaki, A.3
Tanaka, T.4
Tanaka, S.5
-
69
-
-
0036719075
-
The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways
-
Conway EM, Van de Wouwer M, Pollefeyt S, Jurk K, Van Aken H, De Vriese A, Weitz JI, Weiler H, Hellings PW, Schaeffer P, Herbert JM, Collen D, Theilmeier G. The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J Exp Med 2002; 196: 565-77.
-
(2002)
J Exp Med
, vol.196
, pp. 565-577
-
-
Conway, E.M.1
Van de Wouwer, M.2
Pollefeyt, S.3
Jurk, K.4
Van Aken, H.5
De Vriese, A.6
Weitz, J.I.7
Weiler, H.8
Hellings, P.W.9
Schaeffer, P.10
Herbert, J.M.11
Collen, D.12
Theilmeier, G.13
-
70
-
-
20944436774
-
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism
-
Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I. The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J Clin Invest 2005; 115: 1267-74.
-
(2005)
J Clin Invest
, vol.115
, pp. 1267-1274
-
-
Abeyama, K.1
Stern, D.M.2
Ito, Y.3
Kawahara, K.4
Yoshimoto, Y.5
Tanaka, M.6
Uchimura, T.7
Ida, N.8
Yamazaki, Y.9
Yamada, S.10
Yamamoto, Y.11
Yamamoto, H.12
Iino, S.13
Taniguchi, N.14
Maruyama, I.15
-
71
-
-
0032532678
-
Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice
-
Jalbert LR, Rosen ED, Moons L, Chan JCY, Carmeliet P, Collen D, Castellino FJ. Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice. J Clin Invest 1998; 102: 1481-8.
-
(1998)
J Clin Invest
, vol.102
, pp. 1481-1488
-
-
Jalbert, L.R.1
Rosen, E.D.2
Moons, L.3
Chan, J.C.Y.4
Carmeliet, P.5
Collen, D.6
Castellino, F.J.7
-
72
-
-
4644240503
-
A protein C deficiency exacerbates inflammatory and hypotensive responses in mice during polymicrobial sepsis in a cecal ligation and puncture model
-
Ganopolsky JG, Castellino FJ. A protein C deficiency exacerbates inflammatory and hypotensive responses in mice during polymicrobial sepsis in a cecal ligation and puncture model. Am J Pathol 2004; 165: 1433-46.
-
(2004)
Am J Pathol
, vol.165
, pp. 1433-1446
-
-
Ganopolsky, J.G.1
Castellino, F.J.2
-
73
-
-
0035136508
-
The characterization of mice with a targeted combined deficiency of protein c and factor XI
-
Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ. The characterization of mice with a targeted combined deficiency of protein c and factor XI. Am J Pathol 2001; 158: 469-79.
-
(2001)
Am J Pathol
, vol.158
, pp. 469-479
-
-
Chan, J.C.1
Ganopolsky, J.G.2
Cornelissen, I.3
Suckow, M.A.4
Sandoval-Cooper, M.J.5
Brown, E.C.6
Noria, F.7
Gailani, D.8
Rosen, E.D.9
Ploplis, V.A.10
Castellino, F.J.11
-
74
-
-
0034041860
-
Combined factor VII/protein C deficiency results in intrauterine death in mice
-
Chan JCY, Cornelissen I, Collen D, Ploplis VA, Castellino FJ. Combined factor VII/protein C deficiency results in intrauterine death in mice. J Clin Invest 2000; 105: 897-903.
-
(2000)
J Clin Invest
, vol.105
, pp. 897-903
-
-
Chan, J.C.Y.1
Cornelissen, I.2
Collen, D.3
Ploplis, V.A.4
Castellino, F.J.5
-
75
-
-
2942720560
-
Structure and functions of the endothelial cell protein C receptor
-
Esmon CT. Structure and functions of the endothelial cell protein C receptor. Crit Care Med 2004; 32 (Suppl. 5): S298-301.
-
(2004)
Crit Care Med
, vol.32
, Issue.SUPPL. 5
-
-
Esmon, C.T.1
-
76
-
-
0034161458
-
Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo
-
Gu JM, Katsuura Y, Ferrell GL, Grammas P, Esmon CT. Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo. Blood 2000; 95: 1687-93.
-
(2000)
Blood
, vol.95
, pp. 1687-1693
-
-
Gu, J.M.1
Katsuura, Y.2
Ferrell, G.L.3
Grammas, P.4
Esmon, C.T.5
-
77
-
-
0036712284
-
Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge
-
Castellino FJ, Liang Z, Volkir SP, Haalboom E, Martin JA, Sandoval-Cooper MJ, Rosen ED. Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge. Thromb Haemost 2002; 88: 462-72.
-
(2002)
Thromb Haemost
, vol.88
, pp. 462-472
-
-
Castellino, F.J.1
Liang, Z.2
Volkir, S.P.3
Haalboom, E.4
Martin, J.A.5
Sandoval-Cooper, M.J.6
Rosen, E.D.7
-
78
-
-
0037044806
-
Disruption of the endothelial protein C receptor gene in mice causes placental thrombosis and early embryonic lethality
-
Gu JM, Crawley JT, Ferrell G, Zhang F, Li W, Esmon NL, Esmon CT. Disruption of the endothelial protein C receptor gene in mice causes placental thrombosis and early embryonic lethality. J Biol Chem 2002; 277: 43335-43.
-
(2002)
J Biol Chem
, vol.277
, pp. 43335-43343
-
-
Gu, J.M.1
Crawley, J.T.2
Ferrell, G.3
Zhang, F.4
Li, W.5
Esmon, N.L.6
Esmon, C.T.7
-
79
-
-
27144449028
-
Extraembryonic expression of EPCR is essential for embryonic viability
-
Li W, Zheng X, Gu JM, Ferrell GL, Brady M, Esmon NL, Esmon CT. Extraembryonic expression of EPCR is essential for embryonic viability. Blood 2005; 106: 2716-22.
-
(2005)
Blood
, vol.106
, pp. 2716-2722
-
-
Li, W.1
Zheng, X.2
Gu, J.M.3
Ferrell, G.L.4
Brady, M.5
Esmon, N.L.6
Esmon, C.T.7
-
80
-
-
25144462156
-
Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin
-
Li W, Zheng X, Gu J, Hunter J, Ferrell GL, Lupu F, Esmon NL, Esmon CT. Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin. J Thromb Haemost 2005; 3: 1351-9.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1351-1359
-
-
Li, W.1
Zheng, X.2
Gu, J.3
Hunter, J.4
Ferrell, G.L.5
Lupu, F.6
Esmon, N.L.7
Esmon, C.T.8
-
81
-
-
0031743385
-
Wallqvist, Dahlback B. Topological studies of the amino terminal modules of vitamin K-dependent protein S using monoclonal antibody epitope mapping and molecular modeling
-
Giri TK, Villoutreix BO, Wallqvist, Dahlback B. Topological studies of the amino terminal modules of vitamin K-dependent protein S using monoclonal antibody epitope mapping and molecular modeling. Thromb Haemost 1998; 80: 798-804.
-
(1998)
Thromb Haemost
, vol.80
, pp. 798-804
-
-
Giri, T.K.1
Villoutreix, B.O.2
-
82
-
-
0034904874
-
Expression of protein S in the murine heart and cultured mouse cardiomyocytes is down-regulated by cytokines
-
Shimokawa T, Yamamoto K, Yamafuji E, Kojima T, Saito H. Expression of protein S in the murine heart and cultured mouse cardiomyocytes is down-regulated by cytokines. Thromb Haemost 2001; 86: 623-9.
-
(2001)
Thromb Haemost
, vol.86
, pp. 623-629
-
-
Shimokawa, T.1
Yamamoto, K.2
Yamafuji, E.3
Kojima, T.4
Saito, H.5
-
83
-
-
0037426374
-
Protein S confers neuronal protection during ischemic/hypoxic injury in mice
-
Liu D, Guo H, Griffin JH, Fernandez JA, Zlokovic BV. Protein S confers neuronal protection during ischemic/hypoxic injury in mice. Circulation 2003; 107: 1791-6.
-
(2003)
Circulation
, vol.107
, pp. 1791-1796
-
-
Liu, D.1
Guo, H.2
Griffin, J.H.3
Fernandez, J.A.4
Zlokovic, B.V.5
-
84
-
-
0032402132
-
Intravascular coagulation activation in a murine model of thrombomodulin deficiency: Effects of lesion size, age, and hypoxia on fibrin deposition
-
Healy AM, Hancock WW, Christie PD, Rayburn HB, Rosenberg RD. Intravascular coagulation activation in a murine model of thrombomodulin deficiency: Effects of lesion size, age, and hypoxia on fibrin deposition. Blood 1998; 92: 4188-97.
-
(1998)
Blood
, vol.92
, pp. 4188-4197
-
-
Healy, A.M.1
Hancock, W.W.2
Christie, P.D.3
Rayburn, H.B.4
Rosenberg, R.D.5
-
85
-
-
0034493782
-
A total fibrinogen deficiency is compatible with the development of pulmonary fibrosis in mice
-
Ploplis VA, Wilberding J, McLennan L, Liang Z, Cornelissen I, DeFord ME, Rosen ED, Castellino FJ. A total fibrinogen deficiency is compatible with the development of pulmonary fibrosis in mice. Am J Pathol 2000; 157: 703-8.
-
(2000)
Am J Pathol
, vol.157
, pp. 703-708
-
-
Ploplis, V.A.1
Wilberding, J.2
McLennan, L.3
Liang, Z.4
Cornelissen, I.5
DeFord, M.E.6
Rosen, E.D.7
Castellino, F.J.8
-
86
-
-
0029147959
-
Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice
-
Suh TT, Holmback K, Jensen NJ, Daugherty CC, Small K, Simon DI, Potter S, Degen JL. Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice. Genes Dev 1995; 9: 2020-33.
-
(1995)
Genes Dev
, vol.9
, pp. 2020-2033
-
-
Suh, T.T.1
Holmback, K.2
Jensen, N.J.3
Daugherty, C.C.4
Small, K.5
Simon, D.I.6
Potter, S.7
Degen, J.L.8
-
87
-
-
2942624713
-
Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction
-
Palumbo JS, Zogg M, Talmage KE, Degen JL, Weiler H, Isermann BH. Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction. J Thromb Haemost 2004; 2: 1368-79.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 1368-1379
-
-
Palumbo, J.S.1
Zogg, M.2
Talmage, K.E.3
Degen, J.L.4
Weiler, H.5
Isermann, B.H.6
-
88
-
-
13244277924
-
Neonatal bleeding and decreased plasma fibrinogen levels in mice modeled after the dysfibrinogen Vlissingen/Frankfurt IV
-
Hogan KA, Merenbloom BK, Kim HS, Lord ST. Neonatal bleeding and decreased plasma fibrinogen levels in mice modeled after the dysfibrinogen Vlissingen/Frankfurt IV. Thromb Haemost 2004; 2: 1484-7.
-
(2004)
Thromb Haemost
, vol.2
, pp. 1484-1487
-
-
Hogan, K.A.1
Merenbloom, B.K.2
Kim, H.S.3
Lord, S.T.4
-
89
-
-
0034977040
-
Synthesis of a mouse model of the dysfibrinogen Vlissingen/Frankfurt IV
-
Hogan KA, Maeda N, Kluckman KD, Lord ST. Synthesis of a mouse model of the dysfibrinogen Vlissingen/Frankfurt IV. Ann NY Acad Sci 2001; 936: 117-21.
-
(2001)
Ann NY Acad Sci
, vol.936
, pp. 117-121
-
-
Hogan, K.A.1
Maeda, N.2
Kluckman, K.D.3
Lord, S.T.4
-
90
-
-
0242663326
-
Control of thrombus embolization and fibronectin internalization by integrin alpha IIb beta 3 engagement of the fibrinogen gamma chain
-
Ni H, Papalia JM, Degen JL, Wagner DD. Control of thrombus embolization and fibronectin internalization by integrin alpha IIb beta 3 engagement of the fibrinogen gamma chain. Blood 2003; 102: 3609-14.
-
(2003)
Blood
, vol.102
, pp. 3609-3614
-
-
Ni, H.1
Papalia, J.M.2
Degen, J.L.3
Wagner, D.D.4
-
91
-
-
1542373667
-
Antibody blockade or mutation of the fibrinogen gamma-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen
-
Jirouskova M, Chereshnev I, Vaananen H, Degen JL, Coller BS. Antibody blockade or mutation of the fibrinogen gamma-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen. Blood 2004; 103: 1995-2002.
-
(2004)
Blood
, vol.103
, pp. 1995-2002
-
-
Jirouskova, M.1
Chereshnev, I.2
Vaananen, H.3
Degen, J.L.4
Coller, B.S.5
-
92
-
-
0034698061
-
Plasminogen is a critical determinant of vascular remodeling in mice
-
Drew AF, Tucker HL, Kombrinck KW, Simon DI, Bugge TH, Degen JL. Plasminogen is a critical determinant of vascular remodeling in mice. Circ Res 2000; 87: 133-9.
-
(2000)
Circ Res
, vol.87
, pp. 133-139
-
-
Drew, A.F.1
Tucker, H.L.2
Kombrinck, K.W.3
Simon, D.I.4
Bugge, T.H.5
Degen, J.L.6
-
93
-
-
0034669975
-
Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells
-
Palumbo JS, Kombrinck KW, Drew AF, Grimes TS, Kiser JH, Degen JL, Bugge TH. Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells. Blood 2000; 96: 3302-9.
-
(2000)
Blood
, vol.96
, pp. 3302-3309
-
-
Palumbo, J.S.1
Kombrinck, K.W.2
Drew, A.F.3
Grimes, T.S.4
Kiser, J.H.5
Degen, J.L.6
Bugge, T.H.7
-
94
-
-
0036894405
-
Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice
-
Palumbo JS, Potter JM, Kaplan LS, Talmage K, Jackson DG, Degen JL. Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice. Cancer Res 2002; 62: 6966-72.
-
(2002)
Cancer Res
, vol.62
, pp. 6966-6972
-
-
Palumbo, J.S.1
Potter, J.M.2
Kaplan, L.S.3
Talmage, K.4
Jackson, D.G.5
Degen, J.L.6
-
95
-
-
0032030912
-
Fibrinogen deficiency is compatible with the development of atherosclerosis in mice
-
Xiao Q, Danton MJ, Witte DP, Kowala MC, Valentine MT, Degen JL. Fibrinogen deficiency is compatible with the development of atherosclerosis in mice. J Clin Invest 1998; 101: 1184-94.
-
(1998)
J Clin Invest
, vol.101
, pp. 1184-1194
-
-
Xiao, Q.1
Danton, M.J.2
Witte, D.P.3
Kowala, M.C.4
Valentine, M.T.5
Degen, J.L.6
-
96
-
-
0037235934
-
Effects of hyperfibrinogenemia on vasculature of C57BL/6 mice with and without atherogenic diet
-
Gulledge AA, McShea C, Schwartz T, Koch G, Lord ST. Effects of hyperfibrinogenemia on vasculature of C57BL/6 mice with and without atherogenic diet. Arterioscler Thromb Vasc Biol 2003; 23: 130-5.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 130-135
-
-
Gulledge, A.A.1
McShea, C.2
Schwartz, T.3
Koch, G.4
Lord, S.T.5
-
97
-
-
0036339952
-
Overexpression of fibrinogen in ApoE*3-Leiden transgenic mice does not influence the progression of diet-induced atherosclerosis
-
Rezaee F, Gijbels MJ, Offerman EH, van der Linden M, De Maat MP, Verheijen JH. Overexpression of fibrinogen in ApoE*3-Leiden transgenic mice does not influence the progression of diet-induced atherosclerosis. Thromb Haemost 2002; 88: 329-34.
-
(2002)
Thromb Haemost
, vol.88
, pp. 329-334
-
-
Rezaee, F.1
Gijbels, M.J.2
Offerman, E.H.3
van der Linden, M.4
De Maat, M.P.5
Verheijen, J.H.6
-
98
-
-
0035878005
-
Wound-healing defects in mice lacking fibrinogen
-
Drew AF, Liu H, Davidson JM, Daugherty CC, Degen JL. Wound-healing defects in mice lacking fibrinogen. Blood 2001; 97: 3691-8.
-
(2001)
Blood
, vol.97
, pp. 3691-3698
-
-
Drew, A.F.1
Liu, H.2
Davidson, J.M.3
Daugherty, C.C.4
Degen, J.L.5
|